Advanced Wound Care Market Forecast 2015-2025

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Advanced Wound Care Market Forecast 2015-2025

Prospects for Leading Companies in Wound Care Biologics, Moist Wound Care and Wound Care Devices

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Contents 1. Report Overview 1.1 Global Advanced Wound Care Market Overview

1.2 Overview of Findings

1.3 Structure of the Report

1.4 Global Advanced Wound Care Market Segmentation

1.5 Why You Should Read This Report

1.6 How This Report Delivers

1.7 Key Questions Answered by This Analytical Report

1.8 Who is This Report For?

1.9 Methodology

1.10 Frequently Asked Questions (FAQ)

1.11 Associated Visiongain Report

1.12 About Visiongain

2. Introduction to Wound and Wound Care 2.1 An Introduction to Skin, Wound and Wound Healing

2.1.1 Acute Wounds

2.1.2 Chronic Wounds

2.1.3 Burns

2.1.4 The Phases of Wound Healing

2.1.4.1 The inflammatory Phase

2.1.4.2 The Proliferation Phase

2.1.4.3 The Fibroblastic Phase

2.1.4.4 The Maturation Phase

2.2 An Introduction to Wound Care

2.2.1 The Role of Wound Dressing

2.2.2 Wound Care: A Journey through History

2.3 Classification of Wound Care Therapies

2.3.1 Traditional Wound Care

2.3.1.1 Composite Dressings

2.3.1.2 Absorptive Dressings

2.3.1.3 Gauze Dressings

2.3.1.4 Contact Layers

2.3.1.5 Compression Therapy

2.3.2 Advanced Wound Care

2.3.2.1 Moist Wound Care

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Contents 2.3.2.1.1 Foam Dressings

2.3.2.1.2 Hydrocolloid Dressings

2.3.2.1.3 Alginate Dressings

2.3.2.1.4 Hydrogel Dressings

2.3.2.2 Wound Care Devices

2.3.2.2.1 Negative Pressure Wound Therapy (NPWT)

2.3.2.2.2 Ultrasound for Wound Therapy

2.3.2.3 Wound Care Biologics

2.3.2.3.1 Skin Replacement Therapies

2.3.2.3.2 Collagen Based Therapies

2.3.2.3.3 Cell Based Therapies

2.4 Regulation of Medical Devices

2.4.1 The US Approval and Regulation System

2.4.2 The EU Approval and Regulation System

2.4.2.1 Post-marketing Surveillance in the EU

3. Advanced Wound Care: World Market 2015-2025 3.1 Wound Care: Global Market Overview

3.2 The World Advanced Wound Care Market

3.3 World Advanced Wound Care Market: Sales Forecast 2015-2025

3.4 Changing Market Shares by Segment 2015-2025

3.5 Advanced Wound Care Market: Drivers and Restraints 2015-2025

4. Moist Wound Care Market 2015-2025 4.1 Moist Wound Care Market Overview

4.2 Moist Wound Care: Market Forecast 2015-2025

4.3 Market Share of Moist Wound Care Products by Type

4.4 Foam Dressing: Market Forecast, 2014-2025

4.5 Leading Products in the Foam Dressing Market

4.5.1 Lyofoam (Mölnlycke)

4.5.2 Allevyn (Smith & Nephew)

4.5.3 Biatain (Coloplast)

4.6 Hydrocolloid Dressing: Market Forecast, 2014-2025

4.7 Leading Products in the Hydrocolloid Dressing Market

4.7.1 DuoDerm (ConvaTec)

4.7.2 Tegaderm Hydrocolloid (3M)

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Contents 4.8 Alginate Dressing: Market Forecast, 2014-2025

4.9 Leading Products in the Alginate Dressing Market

4.9.1 Sorbsan (Aspen)

4.9.2 Kaltostat (ConvaTec)

4.10 Hydrogel Dressing: Market Forecast, 2014-2025

4.11 Leading Products in the Hydrogel Dressing Market

4.11.1 IntraSite (Smith & Nephew)

4.11.2 Purilon (Coloplast)

4.12 Other Moist Wound Dressing: Market Forecast, 2014-2025

4.13 Leading Products in the Other Moist Wound Dressing Market

4.13.1 Aquacel (ConvaTec)

4.13.2 Xtrasorb HCS (Derma Sciences)

4.14 Moist Wound Care Pipeline Analysis 2015-2025

4.14.1 ProNOx1 (EdixoMed)

4.15 SWOT Analysis of the Moist Wound Care Market, 2015-2025

4.15.1 Strengths

4.15.1.1 Greater Effectiveness Compared with Traditional Wound Care

4.15.1.2 Large Range of Available Products

4.15.2 Weaknesses

4.15.2.1 A Diminishing R&D Pipeline

4.15.2.2 Lower Effectiveness in Comparison to Some Devices and Biologics

4.15.3 Opportunities

4.15.3.1 More Affordable Compared to Other Devices and Biologics

4.15.3.2 Increasing Prevalence of Chronic Wounds

4.15.4 Threats

4.15.4.1 The Threat of Emerging Technologies

4.15.4.2 Decreasing R&D Funding will Impact on Innovation

5. Wound Care Devices Market 2015-2025 5.1 Wound Care Devices Market Overview

5.2 Wound Care Devices: Market Forecast 2015-2025

5.3 Market Share of Leading Wound Care Devices by Type

5.4 Negative Pressure Wound Therapy (NPWT): Market Forecast, 2014-2025

5.5 Leading Products in the NPWT Market

5.5.1 V.A.C. Therapy (KCI)

5.5.2 Renasys (Smith & Nephew)

5.5.3 SNaP (Spiracur)

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Contents 5.5.4 Other NPWT Devices

5.6 Ultrasound Wound Therapy: Market Forecast, 2014-2025

5.7 Leading Products in the Ultrasound Wound Therapy Market

5.7.1 MIST Therapy (Celleration)

5.7.2 Other Ultrasound Devices

5.8 Other Wound Care Devices: Market Forecast, 2014-2025

5.9 Leading Products in the Other Wound Care Device Market

5.9.1 Micro-Z Mini DC Stimulator (Prizm Medical)

5.10 Wound Care Devices Pipeline Analysis 2015-2025

5.10.1 dermaPACE (Sanuwave Health)

5.10.2 Red Light Wave Therapy (Lightwave Technologies)

5.11 SWOT Analysis of the Wound Care Devices Market, 2015-2025

5.11.1 Strengths

5.11.1.1 Continuous Innovation and a Strong R&D pipeline

5.11.1.2 Higher Effectiveness Compared with Other Treatments

5.11.2 Weaknesses

5.11.2.1 The Dominance of Negative Pressure Wound Therapy

5.11.2.2 An Oligopolistic Market


5.11.3.1 Decreasing Prices will Drive Market Growth

5.11.3.2 Increasing Prevalence of Chronic Wounds

5.11.4 Threats

5.11.4.1 Litigation: A Threat to Innovation

6. Wound Care Biologics Market 2015-2025 6.1 Wound Care Biologics Market Overview

6.2 Wound Care Biologics: Market Forecast 2015-2025

6.3 Market Share of Leading Wound Care Biologics by Type

6.4 Skin Replacement Therapy: Market Forecast, 2014-2025

6.5 Leading Products in the Skin Replacement Therapy Market

6.5.1 Apligraf (Organogenesis)

6.5.2 Dermagraft (Organogenesis)

6.5.3 EpiFix (MiMedX)

6.5.4 Graftjacket (KCI)

6.5.5 Other Skin Replacement Therapies

6.6 Collagen Based Therapy: Market Forecast, 2014-2025

6.7 Leading Products in the Collagen Based Therapy Market

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Contents 6.7.1 BioStep (Smith & Nephew)

6.7.2 SkinTemp (Human BioScience)

6.7.3 Promogran (Systagenix)

6.7.4 Other Collagen Based Therapies

6.8 Cell Therapy: Market Forecast, 2014-2025

6.9 Leading Products in the Cell Therapy Market

6.9.1 Regranex (Smith & Nephew)

6.9.2 Aurix System (Nuo Therapeutics)

6.9.3 Other Cell Therapies

6.10 Other Biologics: Market Forecast, 2014-2025

6.11 Leading Products in the Other Biologic Therapy Market

6.11.1 Santyl (Smith & Nephew)

6.12 Wound Care Biologics Pipeline Analysis 2015-2025

6.12.1 CureXcell (Macrocure)

6.12.2 Skin Cell Gun (Mc Gowan Institute for Regenerative Medicine: University of Pittsburgh)

6.12.3 Mesenchymal Stem Cells (Nara University)

6.12.4 Phytochemical Tissue Bonding (Harvard University Institute of Photomedicine)

6.12.5 HP802-247 (Smith & Nephew)

6.12.6 DermaFuse (Missouri S&T and Mo-Sci Corporation)

6.12.7 e-Skin (UC Berkeley)

6.12.8 Automated Artificial Skin Production (Fraunhofer Institute)

6.12.9 Collagen Based Wound Therapy (Cornell University)

6.12.10 ReCell (Avita Medical)

6.13 SWOT Analysis of the Wound Care Biologics Market, 2015-2025

6.13.1 Strengths

6.13.1.1 Fresh Innovations Producing New Technologies

6.13.1.2 Greater Effectiveness of Biologics

6.13.1.3 Rich R&D Pipeline: A Driver for Market Growth

6.13.2 Weaknesses

6.13.2.1 Barriers to Entry: High

6.13.2.2 The Dominance of Small Biotech Companies

6.13.2.3 Price: A Potential Restraint to Reimbursement


6.13.3.1 The Prospect of Diagnostic Testing

6.13.3.2 Rising Prevalence of Chronic Wounds

6.13.3.3 Stem Cells for the Treatment of Multiple Indications

6.13.4 Threats

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Contents 6.13.4.1 The Competition from Moist Wound Care and Devices

6.13.4.2 High Risk: A Strong Deterrent

7. Leading National Markets 2015-2025 7.1 Geographical Breakdown of the World Advanced Wound Care Market

7.2 World Advanced Wound Care Market: Regional Forecast 2015-2025

7.2.1 How Will Regional Market Shares Change to 2025?

7.3 The US Advanced Wound Care Market 2015-2025

7.3.1 US Advanced Wound Care Market Forecast 2015-2025

7.3.2 US Advanced Wound Care Market: Trends and Developments

7.4 The EU5 Advanced Wound Care Market 2015-2025

7.4.1 EU5 Advanced Wound Care Market Forecast 2015-2025

7.4.1.1 German Advanced Wound Care Market Forecast 2015-2025

7.4.1.2 French Advanced Wound Care Market Forecast 2015-2025

7.4.1.3 UK Advanced Wound Care Market Forecast 2015-2025

7.4.1.4 Spanish Advanced Wound Care Market Forecast 2015-2025

7.4.1.5 Italian Advanced Wound Care Market Forecast 2015-2025

7.5 The Japanese Advanced Wound Care Market 2015-2025

7.5.1 Japanese Advanced Wound Care Market Forecast 2015-2025

7.5.2 Japanese Advanced Wound Care Market: Trends and Developments

7.6 The Chinese Advanced Wound Care Market 2015-2025

7.6.1 Chinese Advanced Wound Care Market Forecast 2015-2025

7.6.2 Chinese Advanced Wound Care Market: Trends and Developments

7.7 The Indian Advanced Wound Care Market 2015-2025

7.7.1 Indian Advanced Wound Care Market Forecast 2015-2025

7.7.2 Indian Advanced Wound Care Market: Trends and Developments

7.8 The Russian Advanced Wound Care Market 2015-2025

7.8.1 Russian Advanced Wound Care Market Forecast 2015-2025

7.8.2 Russian Advanced Wound Care Market: Trends and Developments

7.9 The Brazilian Advanced Wound Care Market 2015-2025

7.9.1 Brazilian Advanced Wound Care Market Forecast 2015-2025

7.9.2 The Evolving Brazilian NPWT Market

7.9.3 Multinationals to Expand in Brazil

7.10 The South Korean Advanced Wound Care Market 2015-2025

7.10.1 South Korean Advanced Wound Care Market Forecast 2015-2025

7.10.2 South Korean Advanced Wound Care Market: Trends and Developments

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Contents 8. Leading Companies in the Advanced Wound Care Market 8.1 Smith & Nephew

8.1.1 Smith & Nephew: Advanced Wound Care Product Portfolio

8.1.2 Smith & Nephew: Financial Overview

8.1.3 Smith & Nephew: Products in Development

8.2 Acelity (KCI, Systagenix and LifeCell)

8.2.1 Acelity: Advanced Wound Care Product Portfolio

8.2.2 Acelity: Financial Overview

8.2.3 Acelity: Recent Developments

8.2.3.1 KCI to Pay Wake Forest University after Settling Patent Dispute

8.2.3.2 KCI Forming Partnership with B. Braun Medical

8.3 Mölnlycke

8.3.1 Mölnlycke: Advanced Wound Care Product Portfolio

8.3.2 Mölnlycke: Financial Overview

8.3.3 Mölnlycke: Recent Developments

8.4 ConvaTec

8.4.1 ConvaTec: Advanced Wound Care Product Portfolio

8.4.2 ConvaTec: Financial Overview

8.4.3 ConvaTec: Recent Developments

8.4.3.1 Patent Dispute with Smith & Nephew

8.4.3.2 ConvaTec for Sale?

8.5 Coloplast

8.5.1 Coloplast: Advanced Wound Care Product Portfolio

8.5.2 Coloplast: Financial Overview

8.6 Organogenesis

8.6.1 Organogenesis: Advanced Wound Care Product Portfolio

8.6.2 Organogenesis: Financial Overview

8.6.3 The End of Lawsuit between MiMedx

9.9 Research Interviews 9.1 Interview with Mr Nissim Mashiach, President and Chief Executive Officer, MacroCure, Tenafly,

New Jersey, US

9.1.1 On the Current State of the Advanced Wound Care Market

9.1.2 On the Fate of the Moist Wound Care Sector

9.1.3 MacroCure’s Place in the Advanced Wound Care Market

9.1.4 On the Company’s Growth Strategy and European Expansion

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Contents 9.1.5 The Multi-Faceted Nature of Wound Care and Wound Healing

9.1.6 On the Challenges Facing the Advanced Wound Care Market

9.1.7 Possible Use of Advanced Wound Care Therapies for Other Indications

9.1.8 Views on the Future Prospects of the Market

9.2 Interview with Mr David Navazio, Chief Executive Officer, Gentell, Bristol, Pennsylvania, US

9.2.1 Providing a “Total Solution”

9.2.2 On the Importance of Education

9.2.3 On Drivers and Restraints of the Market

9.2.4 Higher Growth Rate than Industry Average

9.2.5 Higher Revenues from Collagen Products

9.2.6 Entering the EU and Latin American Markets

10. Conclusions 10.1 The World Advanced Wound Care Market in 2014 and 2015

10.1.1 Current Leading Advanced Wound Care Segments

10.1.2 Leading Advanced Wound Care Companies

10.1.3 Leading Regional Markets

10.2 World Advanced Wound Care Market Forecast 2015-2025

10.3 The Future of the Advanced Wound Care Market?

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Advanced Wound Care Market Forecast 2015-2025: Prospects for Leading Companies in Wound Care Biologics, Moist Wound Care and Wound Care Devices

dressings, especially foam dressings. Multinationals will also find it difficult to compete with

cheaper generic products.

Visiongain forecasts the revenue from hydrocolloid dressings to reach $1,439m in 2019 (Table 4.3

and Figure 4.6), growing at a CAGR of 2.5% from 2014. This market is dominated by multinational

companies such as 3M, ConvaTec, Smith &Nephew and Coloplast who have been in the market

for a long time. Visiongain predicts even slower growth in the second half of the forecast period,

with the market growing to $1,613m in 2025, at a CAGR of 1.9% from 2019 to 2025.

Table 4.3 Hydrocolloid Dressing Market Forecast: Revenues ($m), AGR (%), CAGR (%), 2014-2025

2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025Hydrocolloid Dressing ($m)

1,272 1,308 1,342 1,375 1,408 1,439 1,470 1,499 1,529 1,558 1,586 1,613

AGR (%) 2.8 2.6 2.5 2.4 2.2 2.1 2.0 2.0 1.9 1.8 1.7CAGR (%, 2014-2019 & 2019-2025)

2.5 1.9

CAGR (%, 2014-2025) 2.2

Figure 4.6 Hydrocolloid Dressing Market Forecast: Revenue ($m), AGR (%), 2014-2025

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Source: visiongain 2015




Figure 6.6 Collagen Based Therapy Market Forecast: Revenue ($m), AGR (%), 2014-2025

6.7 Leading Products in the Collagen Based Therapy Market

6.7.1 BioStep (Smith & Nephew)

Biostep is a collagen matrix dressing that deactivates excess metalloproteases (MMPs) and has a

6-day wear time for prolonged control of the wound environment. The matrix also contains alginate

for absorbing exudates, and carboxymethylcellulose to ensure close contact with the wound. The

gelling actions also provide a cooling, soothing effect for enhanced patient comfort.

Two main functions of Biostep include:

• MMP Targeting: contains both type 1 and denatured (gelatin) porcine-derived collagen,

and attracts and serves as sacrificial substrates for many MMPs

• MMP Deactivation: contains EDTA which permanently deactivates excess MMPs,

providing prolonged, targeted MMP control without altering the activity of essential growth

factors

Biostep Ag has a further antibacterial activity of silver to help control contaminated and colonised

wounds.

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Table 7.8 Spanish Advanced Wound Care Market Forecast: Revenues ($m), AGR (%), CAGR (%), 2014-2025

2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025Spain ($m) 206 216 227 239 250 262 274 286 299 312 326 340AGR (%) 4.8 5.2 5.2 4.8 4.8 4.6 4.4 4.4 4.4 4.4 4.3CAGR (%, 2014-2019 & 2019-2025)

5.0 4.4

CAGR (%, 2014-2025) 4.7

Figure 7.15 Spanish Advanced Wound Care Market Forecast: Revenues ($m), AGR (%), 2014-2025

7.4.1.5 Italian Advanced Wound Care Market Forecast 2015-2025

High public debt, inflation, and a weakening of the Euro have led to a decrease in Italy’s

Purchasing Power Parity (PPP) GDP in the last few years. The political and economic instability

also has negatively impacted the Italian healthcare system as a whole.

The Italian medical device market traditionally dependents on imported products. The payment

delay from the public sector is the main barrier that threatening small medical device companies

On the other hand, the adoption of the latest EU Directive on delayed payments may make it a

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Figure 8.6 Organogenesis: Advanced Wound Care Revenue ($m), AGR (%), 2014-2025

8.6.3 The End of Lawsuit between MiMedx

In February 2015, Organogenesis announced that MiMedx, another skin allograft manufacturer,

has dismissed a lawsuit against the Organogenesis. According to the company, they informed

MiMedx that Organogenesis will seek sanctions against MiMedx and its counsel unless the case is

dismissed before 5th February.

The case was filed on the last day of 2014, and dismissed after one month. MiMedx claimed that

Organogenesis was engaged in malicious actions which resulted in MiMedx‘s EpiFix removed from

the Federal Supply Schedule (FSS) of the Veterans Administration in June 2013. EpiFix was later

added back to the list. Although the lawsuit was withdrawn, MiMedx announced that the company

"continues to believe that Organogenesis has engaged in misconduct against MiMedx."

In August 2014, Organogenesis also announced that the company has been awarded VA’s FSS

Contract for Apligraf. This five-year contract will streamline the purchasing process for Veterans

Affairs Medical Centers to gain easier access to Apligraf.

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Business

Advanced Wound Care Market Forecast 2015-2025