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Targeted Natural Antioxidants
We all want to look like
this
We’re all going to look like
this
Global Anti Aging Market:
$138B*
Anti-aging Skin Care Market
$22.5B**
Values for 2015 *Transparency market Research **Assumption based on Euromonitor
Research shows skin anti-aging cosmetics
Don’t actually
work.Jacquelyn Levin et al J Clin Aesthet Dermatol. 2010 Feb; 3(2): 22–41.
http://phys.org/news/2011-02-anti-aging-skin-creams-dermatologists.html http://www.webmd.com/beauty/aging/hope-in-jar-do-skin-creams-work
Skin cells have a component
called Mitochondria
Mitochondria produce the energy that skin cells need
but are easily damaged by oxidation, they swell up, burst and the cell dies.
Oxidation
This whole sequence of events is one of the main causes of skin
aging (~90%)Krutmann J, Schroeder P. Role of mitochondria in photoaging of human skin: the defective powerhouse model. J Investig Dermatol Symp Proc. 2009;14(1):44-9.
Menon GK, Dal farra C, Botto JM, Domloge N. Mitochondria: a new focus as an anti-aging target in skin care. J Cosmet Dermatol. 2010;9(2):122-31.
Unfortunately, most antioxidants
very low cell penetration
require high doses
are not effective
The few antioxidant molecules that enter the cell are not accumulated by mitochondria.
You cannot hit a target if you are not aiming for it.
Natural
AntioxidantGuidance
System
We linked a chemical “Guidance System” to natural antioxidants to target them
to mitochondria.
5000x We measured up to
greater accumulation in mitochondria
Targeted antioxidant
Products with untargeted antioxidants
MitoDIETS vs MitoQIn Vitro laboratory testing confirmed that MitoDIETS:
95x better protection against mitochondrial rupture
2-3x better safety profile on mitochondria
95x better protection against mitochondrial oxidation
promoted by free iron
Premium Anti-aging Skin Care Products Total $15B*
4.3% Growth Rate
* Euromonitor data: 14 most relevant markets for 2014- accounting for 50% of the total market. For Anti-Ageing and Premium Health Care Products only
B2B supply of MitoDIETS antioxidant active ingredients to Cosmetic Companies.
MitoDIETS is a Platform Technology:Human Health (Liver Diseases $10.4 B)
Veterinary (Pet Supplements $1.46B)
Why Cosmetics then?
High Demand for fast solution.Time to market 3 years
YEAR 2Q1 Q2 Q3 Q4
Efficacy Tests
€92.4kFormulation + Shelf Life Tests €18.5k
Operating Expenses €352k
YEAR 3Q1 Q2 Q3 Q4
Operating Expenses €442.8k
Total Investment €1.76M
IP Protection
50k
Scale up Production €150k Scale up Production €250k
YEAR 1Q1 Q2 Q3 Q4
Safety Tests
€92.4k
IP Protection
15k
Scale up optimization
€54k
Roadmap
MEET OUR TEAM
António SantosBusiness
Development
José DuarteMarketing &
Communication
Fernanda BorgesPhD.
Scientific Advisor
Paulo OliveiraPhD.
Scientific Advisor
MitoDIETS will provide targeted natural antioxidants
that will enable game changing anti-aging skin care products for the cosmetic industry.
We all want to look like
thiswww.mitodiets.eu
