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Decreased O2 fow to thekidney
• Proximal tubule & Medullamost afected
Renal Dysplasia • MC Cystic Disease ankmass in newborns
• Newborn w/ a unilateral
mass Juvenile Polycystic Disease • Potter’s
acies
• Olio!ydramnios
• "#$ Can’t sur%i%e
Adult Polycystic Disease • "D ilateral disease
• '(N can lead to berryaneurysms )bloody brain*
o +Worst headacheever”
• "ssoc, w/ M-P
•
Diabetic gloerulopathy
'yaline arteriosclerosis
Proteinuria .,/01!r
Caused by !y2ertension
!inial "hange Disease
MCC o Ne2!rotic syndromein c!ildrenDue to ($cell 2roduction
ocytokines,
3oss o neati%e c!are ont!e 4M
'y2oalbuminemia causin Ca
5used 2odocyte eet
(x6 im2ro%e w/corticosteroids
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Progressive "resenticgloerulonephritis
Can occur ater takin2enicillin
'ematuria7 #C casts
Proressi%e renal ailure
4enerali8ed 2al2able2ur2ura
2$"NC"s#oodpastures syndroe
'emo2tysis ollowed byacute renal ailure
'ematuria7 2roteinuria and#C casts
3inear 95
94 anti$basementmembrane
Di$use proli%erativegloerulonephritis
MC ty2e o lomerulone2!ritisin 2atients wit! :3;
P!oto2!obia and stifness in
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Alport &yndroe • ? linked recessi%e
• Mutation o (y2e 9-Collaen
• :ensorineural !earin lossand ocular abnormalities
• Neati%e 95 and ;MAcute Post+&treptococcal #* •
(y2e 999 #xn
• :mokey colored urine
• :ube2it!elial de2osits95ranular
• ollows stre2 " in,
• "nti$DN"ase "b’s
• #C cast)ype ' !P#* • "ssociated w/ '- & 'C-
• :ubendot!elial 95 ranular
de2osits• (ram$(rack
)ype ', &-. gloerulonephritis • "nti$dsDN" "b’s
• >ire loo2in
• 4ranular 95
'gA gloerulopathy • .pisodic !ematuria
• "ssociated w/ 'enoc!$:c!onlein 2ur2ura, )(y2e 999*
• 'ematuria and #C cast
• O%erall MC ty2e
!edullary &ponge /idney • :triations in 2a2illary
ducts
• disco%ered w/ 9-P
• #ecurrent @(9’s and renalstones
Juvenile autosoal recessivepolycystic kidney disease
• Potter’s ace$ low set earbroad base nose etcA
• Olio!ydramnios
• "#$ PB'D ene mutation
• Cysts also in li%er&taghorn "alculus • C!ronic
urinary (ract
inections• 3"#4; stones causin
!ydrone2!rosis• (ri2le 2!os2!ate crystal
• Caused by a Proteusspecies
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0
• "lkaline urine
Acute Drug+induced )'* • ;osino2!ilia/;osino2!ils
inurine
• (y2e 9 & 9- 'y2ersens #xn
• :terile 2yruia )NO bacteriaand >C cast*
• Occurs ater takin2enicillin ty2e dru orN:"9D:
• Post (x rom acute sinusitisRenal )1 • -ery common in
Nati%e
"mericans• :terile 2yruia
• Bidney is MC extra2ulmonary site
Wils )uor • @nilateral abdominal massin c!ild w/
!y2ertension
• '(N due to renin secretionrom tumor
• MC 2rimary renal tumor inB9D:
• "borti%e lomeruli
• mesono2!reic mesoderm
Renal "ell "arcinoa • MCC is :mokin
• Microsco2ic !ematuria
• E$Ft! decade o lieAngioyolipoa • "ssociated w/
Mental
#etardation & (uberous:clerosis
• ilateral :olid Mass)ransitional "ell "arcinoa • "niline
dye ex2osure
• "fects #enal 2el%is
• :mokin MCC
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• P!anacetin abuse alsocause
• "nalesic abuse
*ephritic &yndroe • #C cast B;G Hndins
• Proteinuria is IJm/day
*ephrotic &yndroe • 5atty casts are B;G Hndin
• 'y2erc!olesterolemiaAcute pyelonephritis • 5e%er
• >C casts
• -esicoureteral reux!alignant 3)* • 5lea$bitten kidney
)2in2oint
!emorr!aes on corticalsurace*
• 'yaline arteriolosclerosis
• Necroti8in lomerulitis
!edullary segent o% )A- • Most susce2tible to9sc!emia
"alciu Phosphate &tones • MC stone in
c!ildrenassociated w/ increaseddiary
Orthostatic proteinuria • 5unctional 2roteinuria
t!atoccurs w/ standin
• mailmenDi$use !ebranous#loerulopath
(!ick 4M
5atty Cast w/ MalteseCrosses
2nd !"" o ne2!roticsyndrome in adults
:ub;P9t!elial de2osits o9C’s
:P9B; "ND DOM;a22earance
4ranular 95
"ssoc, w/ '- andCa2to2ril )"C;i*
(y2e 999 'y2ersen #xn,
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"hronic R.*A- (A'-4R. • "cellular >"?G cast
• @N and Cr )renal a8o*
• P(' )Ca* ) -it D*
• P!os2!orus
•
Renal papillary *ecrosis • C!ronic
dru$inducedtubulointerstitial ne!ritis
• rin deormities in t!ekidneyK absence or renal2a2illae
• 59?;D s2eciHc ra%ity
