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3T NeuroImaging

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3T NeuroImaging. Primate Chair. Jennifer Pryweller. Sponsor: Dr. Calum Avison, Vanderbilt University Institute of Imaging Science. Philips 3T Achieva. Visual Cortex. fMRI brain scan BOLD. Objectives. CPU Cortex/LabView. monitor. visual task. IR camera. audio tone. juice - PowerPoint PPT Presentation

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Page 1: 3T NeuroImaging
Page 2: 3T NeuroImaging

Philips 3T Achieva

Visual Cortex

fMRI brain scan BOLD

Page 3: 3T NeuroImaging

MONK

RF signal

audiotone

juicecontroller

juicedispenser

solenoidEMG

neuronAP

fMRI BOLD

visualtask

IRcamera

CPUCortex/LabView

monitor

Page 4: 3T NeuroImaging

• Non-human primate of choice:

• anatomical & physiological likeness

• ease of maintaining & breeding in captivity

• No harm / minimize discomfort

• IACUC (Institutional Animal Care and Use Committee)

• IRB (Institutional Review Board) approval

• Ethics Research Training (exam #1102055)

Page 5: 3T NeuroImaging

Wim Vanduffel (2001)

Mark Pinsk (2004)

Crist Instruments (current)

Page 6: 3T NeuroImaging

Improvements: mechanical design, materials selection, audio reinforcement, component

integration

Page 7: 3T NeuroImaging

General Property ASTM Test Typical Value

Specific Gravity D792 1.2

Tensile Strength Yield D638 8,900 - 9,000

Tensile Modulus D638 340,000

Izod Impact - Notched D256 12-16

Hardness - Rockwell D785 M70

Deflection Temp @ 264psi D648 270

Deflection Temp @ 66 psi D648 280

Co. Thermal Expansion D696 3.7X10-5

General Property ASTM Test Typical Value

  Specific Gravity  D792 1.19

  Tensile Strength Yield D638 10,000

  Tensile Modulus D638 400,000

  Izod Impact - Notched D256 0.4

  Hardness - Rockwell D785 M94

  Deflection Temp @ 264psi D648 210

  Deflection Temp @ 66 psi D648 239

  Co. Thermal Expansion D696 3.4X10-5

Polycarbonate material properties

Acrylic material properties

Page 8: 3T NeuroImaging

Max. Available Diameter Polycarbonate Acrylic

Applied Plastics Co 8” 8”

Industrial Plastic Supply, Inc 4” 24”

Inplex LLC 3.5” n/a

McMaster-Carr** 8” (± .04) 18” (± .08)

Modern Plastics 8” (± .03) 6”

Scandia Plastics Inc 8” n/a

US Plastics 4” 12”

Tubing Availability

**preferred company

Page 9: 3T NeuroImaging

CAST ACRYLIC (LUCITE) TUBE

outside diameter: 15”16” 18”

Length 24"Length Tolerance +.25"Inside Diameter 14-3/4"Outside Diameter 15"Outside Diameter Tolerance ±.08"Wall Thickness .125"Wall Thickness Tolerance ±.02"Acrylic Material Cast AcrylicPart No. 84865K317

Cost: $311.42

Length 24"Length Tolerance +.25"Inside Diameter 15-1/2"Outside Diameter 16"Outside Diameter Tolerance ±.08"Wall Thickness .25"Wall Thickness Tolerance ±.025"Acrylic Material Cast AcrylicPart No. 84865K418

Cost: $438.64 

Length 48"Length Tolerance +.25"Inside Diameter 15-1/2"Outside Diameter 16"Outside Diameter Tolerance ±.08"Wall Thickness .25"Wall Thickness Tolerance ±.018"Acrylic Material Cast AcrylicPart No. 84865K438

Cost: $871.70 

Length 48"Length Tolerance +.25"Inside Diameter 17-1/2"Outside Diameter 18"Outside Diameter Tolerance ±.08"Wall Thickness .25"Wall Thickness Tolerance ±.018"Acrylic Material Cast AcrylicPart No. 84865K439

Cost: $884.35

Length 24"Length Tolerance +.25"Inside Diameter 17-1/2"Outside Diameter 18"Outside Diameter Tolerance ±.08"Wall Thickness .25"Wall Thickness Tolerance ±.025"Acrylic Material Cast AcrylicPart No. 84865K419

Cost: $444.95

Source: www.mcmaster.com

Page 10: 3T NeuroImaging

grate/perforated slab of steel or aluminum

disposable, removable lining across bottom

vertices glued and waterproof

recessed ¼”, 20 thread screws

rapid prototyping

machine

¼”, 20 thread, nylon screws

aluminum, brass, plastic stainless steel

appr

oxim

ate

piano hinge along tube (?)

Page 11: 3T NeuroImaging

= isocenter, 23.255cm from base

Philips 3T Achieva

8.255

45.72

15.00

26.942

23.255

3.969

41.751

NOT DRAWN TO SCALE

Based on our measurements of the bohr…

Tube (15” diameter) radius = 19.05cm

Tube (16” diameter) radius = 20.32cm

Tube (18” diameter) radius = 22.86cm

Page 12: 3T NeuroImaging

Philips 3T Achieva

NOT DRAWN TO SCALE

Page 13: 3T NeuroImaging

Philips 3T Achieva

NOT DRAWN TO SCALE

Page 14: 3T NeuroImaging

Units = inches

Page 15: 3T NeuroImaging

Units = inches

Page 16: 3T NeuroImaging

Units = inches

Page 17: 3T NeuroImaging

• Mechanical design model, checking with Princeton

• Macaque measurements: 6.5-8.5kg, 28-32” prone

• Chair: landmark, loading, attach

• chair weight• final design revisions• machine the chair

• Mock scanner environment• Monkey training• RF coil selection & construction• Functional components: QFDs & selection

Page 18: 3T NeuroImaging