AACR Annual Meeting 2013

C A L L F O R A B S T R A C T S

Abstract Submission Deadline: November 15, 2012 www.AACR.org

A N N U A LMEETING

2013

“Personalizing Cancer Care Through Discovery Science”

April 6-10, 2013Walter E. WashingtonConvention CenterWashington, DC

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ANNuAl MEETiNg 2013

PRogRAM, EDuCATioN, AND ExhibiTS CoMMiTTEES

2013 AACR Annual

Meeting Scientific

Program Committee

Chairperson

José Baselga

Co-Chairpersons

Cory Abate-Shen

James P. Allison

René Bernards

Lewis C. Cantley

Andrew J. Dannenberg

James R. Downing

Jeffrey A. Engelman

Keith T. Flaherty

Peter W. Laird

Michael J. Luzzio

Elaine Mardis

Yusuke Nakamura

William R. Sellers

Phillip A. Sharp

M. Celeste Simon

Eileen P. White

Program Committee

Members

Angelika B. Amon

Samuel Aparicio

Carlos L. Arteaga

Laura D. Attardi

Alberto Bardelli

Dafna Bar-Sagi

Nina Bhardwaj

Jean-Yves Blay

Peter J. Campbell

James R. Cerhan

Arul M. Chinnaiyan

Karen Cichowski

Ezra E. W. Cohen

Joseph F. Costello

Tom Curran

Riccardo Dalla-Favera

Steven K. Davidsen

Johann S. de Bono

Phillip A. Dennis

Titia de Lange

Hugues de Thé

J. Alan Diehl

Brian J. Druker

Stephen W. Fesik

Thomas F. Gajewski

Maura L. Gillison

William M. Grady

Philip D. Greenberg

Sean Grimmond

Kristian Helin

James G. Herman

Thomas J. Hudson

Patrick Humbert

Luisa Iruela-Arispe

Peter K. Jackson

Pasi A. Jänne

Randall S. Johnson

Yibin Kang

Michael B. Kastan

Nicholas J. Keen

Thomas W. Kensler

Guido Kroemer

Jin Soo Lee

John P. Leonard

Ross L. Levine

A. Thomas Look

Patricia M. LoRusso

Scott W. Lowe

John M. Maris

Wells A. Messersmith

Kohei Miyazono

Robert A. Mook, Jr.

Stephen D. Nimer

Garry P. Nolan

Ramon E. Parsons

Charles M. Perou

Kornelia Polyak

Neal Rosen

Martine F. Roussel

David M. Sabatini

Yardena Samuels

Charles L. Sawyers

Robert D. Schreiber

Kevin M. Shannon

Jerry W. Shay

Alice T. Shaw

David B. Solit

Margaret R. Spitz

Kimberly Stegmaier

Josep Tabernero

David E. Uehling

Matthew G. Vander Heiden

Laura J. van ‘t Veer

Karen H. Vousden

Timothy C. Wang

Education Committee

Co-Chairpersons

Lewis C. CantleyJeffrey A. EngelmanPeter W. LairdElaine MardisM. Celeste Simon

Education Committee

Members

Ron BoseJames E. BradnerRobert J. Coffey, Jr.Andrew J. DannenbergNancy E. DavidsonKeith T. FlahertyElsa R. FloresSanjiv GambhirAmato J. GiacciaMargaret A. GoodellLuisa Iruela-ArispeKimberly J. JohnsonRaghu Kalluri

Albert C. LockhartDavid C. LydenCynthia X. MaUrsula A. MatulonisAri M. MelnickGordon B. MillsTony S. K. MokWilliam G. NelsonJacqueline PaytonHelen M. Piwnica-WormsEllen PuréAndrea L. RichardsonSandra W. RyeomYardena SamuelsChris Sander

Ralph ScullyKimberly D. SiegmundNancy A. SpeckMuneesh TewariDavid A. TuvesonCornelia M. UlrichGiske UrsinToshikazu UshijimaMatthew G. Vander HeidenRobert H. VonderheideKaren H. VousdenGeoffrey M. WahlMatthew J. WalterZena Werb Kwok-Kin Wong

Exhibits Committee

Chairperson

Ethan Dmitrovsky

Exhibits Committee

Members

Edward Chu

Nicholas C. Dracopoli

Elizabeth A. Grimm

Patricia M. LoRusso

Patricia S. Steeg

Chris Takimoto

Clinical Trials Committee

Appointments pending

AACR ANNUAL MEETING 2013 Abstract Submission Deadline: November 15, 2012

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AACR Officers

President

Frank McCormickPresident-Elect

Charles L. SawyersTreasurer

William N. HaitPast President

Judy E. GarberChief Executive OfficerMargaret Foti

Board of Directors

Until 2013Todd R. GolubJennifer Rubin GrandisSir David P. LaneKornelia PolyakOwen N. Witte

Until 2014Joan S. BruggeArul M. ChinnaiyanThomas A. SellersLaura J. van ‘t VeerKristiina Vuori

Until 2015Kenneth C. AndersonLewis C. CantleyMichelle M. Le BeauBenjamin G. NeelKaren H. Vousden

Table of ContentsIFC AACR Annual Meeting 2013inside Program, Education, and Exhibits Committeesfrontcover

4 Letter from the President and Program Committee Chairperson

6-11 Program in Progress

6 Plenary Sessions

7 Major Symposia

8 Current Concepts Sessions

9 Forums and Meet-the-Expert Sessions

10 Professional Advancement Sessions

12-25 Guidelines for Preparation and Submission of Abstracts

12 What You Need to Submit an Abstract

13 Procedure for Submitting Abstracts

14 Late-Breaking Abstracts

16 Abstract Sponsorship Regulations

18 Spotlight on Clinical Research

20 Abstract Categories

26 Membership Categories

27 Financial Support for Attendance

28 Housing

29 Travel

30 AACRcentral

32 Mobile Technology at the Annual Meeting

33 Annual Meeting Print Publications

34 Registration

37 Housing Form

38 Hotel List

40 Hotel Map

IBC General Informationinside back cover 1

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AACR ANNUAL MEETING 2013 Abstract Submission Deadline: November 15, 2012 2

“Overall, the meeting wasinspirational and should lead to many fruitful collaborations.It's a unique opportunity for thecancer research community tocommunicate ideas acrosscancer disciplines… ”


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Why You Should Attend

It has been said around the world that the AACR Annual Meeting drives the canceragenda. This meeting brings together the best and latest findings in all major areas ofcancer research. Through plenary sessions, symposia, forums, educational sessions,methods workshops, poster presentations, conversations with experts, and networking,attendees walk away with a wealth of new information, more connections, and renewedenergy, inspiration, and focus in their work. A past attendee notes: “Overall, the meetingwas inspirational and should lead to many fruitful collaborations. It's a unique opportunityfor the cancer research community to communicate ideas across cancer disciplines…”

Last year, nearly 17,000 participants from 70 countries gathered to discuss over 6,100abstracts and to hear invited presentations from 750 speakers on new and significantdiscoveries in basic science, translational research, clinical trials, and populationsciences. The 2012 Annual Meeting featured:

• 6,162 proffered papers presented in 210 poster sessions and 30 minisymposia

• 267 sessions accredited for continuing medical education for a total of 45.5 AMA PRA Category 1 Credits™

• 50 educational sessions and methods workshops for those seeking a foundation ofknowledge in rapidly developing areas

• 14 professional advancement activities covering topics such as grant writing, gettingyour research published, and the mentor-mentee relationship

• 843 webcasts of the scientific talks available to attendees and subscribers

• 458 exhibiting companies in 779 booths at the exhibition

• Over 21 trillion media impressions resulting from press coverage of hot topics in manymajor outlets including The Wall Street Journal, The New York Times, HealthDay, Yahoo!News, Associated Press, The Los Angeles Times, USA Today, U.S. News & WorldReport, Huffington Post, Gizmodo, Reuters, The Economist, and more

What You Can’t Afford to Miss

Be a part of the AACR Annual Meeting 2013 so you won’t miss:

• The premier meeting in cancer research where you are among the best and thebrightest in the cancer field from around the world

• Participation in abstract submissions and presentations

• The latest developments in basic science, translational research, clinical trials, andpopulation sciences

• Our online itinerary planner that allows you to search and schedule the topics,speakers, and posters that are of interest to you

• A multitude of networking events and professional development activities, plus theannual Cancer and Biomedical Research Career Fair



Dear Members, Colleagues, and Friends of the AACR,

It is our pleasure to announce and invite you to attend the 104th Annual Meeting of the AmericanAssociation for Cancer Research, to be held April 6-10, 2013, in Washington, DC. As always, this AACRAnnual Meeting will highlight the latest and most exciting discoveries in every area of cancer research, andit will provide a unique opportunity for investigators from all over the world to meet and interact. Being inWashington, DC, at this time will give us a special opportunity for our collective voices to be heard, andseveral sessions and events will emphasize the vital importance of reaffirming our Nation’s commitment tothe conquest of cancer.

The Annual Meeting scientific program will feature daily plenary sessions, major symposia, minisymposia,forums, educational sessions, methods workshops, poster sessions, “Meet-the-Expert” sessions, “CurrentConcepts in Organ Site Research” sessions, “Current Concepts in Diagnostics and Therapeutics” sessions,and an exciting new series of sessions focused on “Current Concepts in Epidemiology and Prevention.”Based on the huge success of last year’s sessions on cutting-edge, science-based clinical trials, we areagain planning to hold several sessions featuring presentations of new data on cutting-edge clinical trialsalong with commentaries on the implications of these trials for improved patient care. We will also befeaturing a poster session on “Clinical Trials in Progress.” In addition, for the second year, we are planning atrack devoted to regulatory science and policy.

This multidisciplinary program is being developed through the devoted efforts of our team ofCo-Chairpersons, whose names are listed in this publication. Together, we are assembling an outstandingroster of speakers who will update participants on their latest research findings. Along with the hundreds ofinvited talks, we will feature over 6,000 proffered papers from researchers all over the world. We want tothank the Program Committee Co-Chairpersons for their incredible expertise and guidance in shaping aninnovative program that will be enjoyable as well as educational.

With the accelerating pace of discoveries in the basic, translational, and clinical sciences, due in large partto the advent of new technologies, cancer researchers are making rapid progress that is having significantpatient benefit. It is clear that in the near future even greater opportunities for the prevention, management,and cures for all types of cancer will abound. We are confident that attending the AACR Annual Meeting willgive you renewed energy, inspiration, and focus in your work.

Please register early and submit your abstract by the November 15, 2012, deadline.

We look forward to seeing you in Washington, DC.

Sincerely,

Frank McCormick, Ph.D., F.R.S., D.Sc. José Baselga, M.D., Ph.D.

AACR President, 2012-2013 Chairperson, 2013 Program Committee


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Plenary Sessions

Opening Plenary Session

Sunday, April 7, 2013

Chairperson: José Baselga,

Massachusetts General Hospital

Cancer Center, Boston, MA

Speakers:

Hans Clevers, Hubrecht Institute,

Utrecht, The Netherlands

Charles M. Perou, University of North

Carolina at Chapel Hill, Chapel Hill, NC

Siddhartha Mukherjee, Columbia

University, New York, NY

Additional speaker to be announced

Epigenetics

Chairperson to be announced

Speakers:

Peter W. Laird, University of Southern

California, Los Angeles, CA

Anjana Rao, La Jolla Institute for

Allergy and Immunology, La Jolla, CA

Robert A. Copeland, Epizyme, Inc.,

Cambridge, MA

Cancer Evolution and Resistance

Chairperson: Jeffrey A. Engelman,

Massachusetts General Hospital,

Boston, MA

Speakers:

Jeffrey A. Engelman

Neal Rosen, Memorial Sloan-Kettering

Cancer Center, New York, NY

Todd R. Golub, Broad Institute of MIT

and Harvard, Cambridge, MA

René Bernards, The Netherlands

Cancer Institute, Amsterdam,

The Netherlands

PROgRAM iN PROgRESS

2013On Saturday, April 6, 2013, a full program of Educational Sessions, MethodsWorkshops, Meet-the-Expert Sessions, and Award Lectures will be presented beginningat 8:00 a.m. The Opening Ceremony and Opening Plenary Session will take place onSunday morning, April 7. The meeting will conclude on Wednesday, April 10. The 2013Program in Progress follows.

Regular updates to the program will be posted on the AACR website (www.aacr.org/AACR2013).



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Adaptive Signaling in Resistance

The Bayard D. Clarkson

Symposium on Stem Cells

and Cancer: Stem Cell Biology

and Therapeutics

Biological and Clinical

Implications of Premalignant

Cancer Lesions

Blood-Based Molecular Analysis

of Cancer

Context-Dependent Functions of

Ras/Raf in Cancer

Developmental Pathways and

Cancer

Emerging Technologies in

Cancer Research

Expanding the Druggable Genome

Genetic Mechanisms for

Resistance and the

Implications/Resistance to

Targeted Therapies

Genomic Characterization of

Mouse Models

The Global Cancer Crisis: Needs

and Opportunities for Prevention

Imaging in Cancer Research

Infections and Cancer:

Can We Cure Cancer

Through Vaccinations?

Innate Sensing in the Tumor

Microenvironment

The Interface Between

Development and Cancer Using

Model Organisms

Large-Scale Genomic Studies of

Human Cancer

Metabolic and Epigenetic

Interactions in Cancer

Metabolic Vulnerabilities of

Cancer Cells

Mitotic Checkpoints Driving

Cancer Therapeutic Strategies

Mutations in Epigenetic Readers,

Writers, and Erasers

New Approaches to

Drug Discovery

New Vaccine Strategies

Noncoding RNAs

Obesity, Energy Balance, and

Metabolism

Ras and Metabolism

The Ruth Sager Memorial

Symposium: Cancer

Heterogeneity

The Stanley J. Korsmeyer

Memorial Symposium: Targeting

Cell Death Pathways for Cancer

Therapy

Strategies to Overcoming Drug

Resistance

Stress Response Pathways in

Cancer

Synthetic Lethality and Its

Discovery

Target Validation by Chemical

Probes/Designer Chemical

Probes and Phenotypic Approach

to Drug Discovery

Targeting the Stroma

Use of Next-Generation

Sequencing: Implementation of

Clinical Genomics

Major Symposia



Current Concepts in Organ Site Research

Bone Metastasis

The Breast Cancer Genome

and Its Implications for Therapy

Classification and

Pathogenesis of Liver Cancers

Druggable Targets in

Ewing’s Sarcoma

Emerging Targets in the

Treatment of Lung Cancer

Epigenetic Mechanisms in

Gastrointestinal Differentiation

and Malignant Transformation

Esophageal Cancer

Genetic Determinants of Brain

Metastasis

Gynecologic Cancer

Latent Metastasis

Lymphoid Malignancies

Melanoma

Myeloid Malignancies

Nervous System Tumors

Pancreatic Adenocarcinoma

Pediatric Tumors

Prostate Cancer: The Dilemma

of Overdiagnosis and

Overtreatment

Targeting Lymphoid

Malignancies: Working from the

Outside In

Current Concepts in Diagnostics andTherapeutics

Advances in Antibody-Drug

Conjugates

Aging, Telomeres, and Cancer

Avatar: Individualized Human

Cancer Models in Mice

Chemical Engineering of

Biologics

Genomics-Driven Immune

Therapeutics

Metformin, Diabetes, and

Cancer

Next-Generation Therapeutic

Modeling in Mice

Novel Mechanisms of

Mutations

Translational Research

Breakthroughs

Current Concepts in Epidemiology andPrevention

Clinical Trials with Functional

Foods

Epigenetic Mechanisms of

Cancer Risk

Human Papillomavirus:

Beyond Cervical Cancer

PROgRAM iN PROgRESS

2013


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Forums

Cancer in the Adolescent and

Young Adult Population

Clinical Trials Based on

Mutations versus Histology

Circulating Tumor Cells versus

Serum DNA

Drug Discovery in Industry,

Academia, and Government—

What Is the Track Record?

Genome-Wide Association

Studies: What We Have

Learned, Future Directions,

Next Generation

Human Variation and Its

Impact on Drug Development

The Role of Stroma in

Pancreatic Cancer

Stem Cells in Cancer

The Utility of Cell Line

Screens for Drug Sensitivities

Meet-the-ExpertSessions

Speakers to be announced



PROgRAM iN PROgRESS

2013

Professional Advancement Sessions

Professional Advancement Sessionshave long been an integral part ofthe AACR Annual Meetingexperience, representing ourdedication to the education, training,and career advancement of cancerresearchers. Sessions are organizedto provide important skills toinvestigators at all levels, from highschool students to senior faculty.We invite you to participate insessions that will enrich your career.

For AACR members, all 2013Professional Advancement Sessionsare free with your Annual Meetingregistration (except for the GrantWriting Workshop) and are an addedbenefit of your membership.

For nonmembers, there is anadditional fee of $45 ($95 for theGrant Writing Workshop) forattendance at each session. If youare not an AACR member, westrongly encourage you to join andtake advantage of the many benefitsof membership, which includeattendance at these sessions.

Advance registration is onlyavailable for the Grant WritingWorkshop. Participation for all othersessions is on a first-come,first-served basis, and space islimited. Nonmembers are required topay on site.

Professional Advancement Sessionsat the Annual Meeting 2013 willinclude the following, with more tobe added soon. For sessionupdates, visit www.aacr.org/pas.

Careers in Clinical andTranslational Cancer ResearchRoundtable

16th Annual Grant Writing WorkshopSaturday, April 6, 2013 12:00 p.m. to 5:00 p.m.Organized by the Associate MemberCouncil (AMC)

This intensive half-day workshopfeatures keynote presentations, amock study section, and ample timefor roundtable discussions withsenior scientists. This session isaimed towards Associate Membersand nonmember graduate students,medical students and residents, andclinical and postdoctoral fellowswith limited or no experience inpreparing grant applications. Lunchwill be provided. Preregistration isstrongly encouraged; there is a $45 registration fee for AACRmembers and a $95 registration feefor nonmembers. To register for theGrant Writing Workshop, check theappropriate box on the OfficialRegistration Form on page 35 orregister online beginning September 27, 2012.

Three additional ProfessionalAdvancement Sessions organized

by the Associate Member Councilwill be announced. Each will beaimed towards the professionalneeds of Associate Members andnonmember graduate students,medical students and residents, andclinical and postdoctoral fellows,and will focus on topics of particularinterest to early-career scientists.

Career Paths in Cancer DrugDevelopmentOrganized by the Chemistry inCancer Research Working Group(CICR) Young Chemists Committee

Navigating the Road to a SuccessfulCareer in Cancer ResearchOrganized by Minorities in CancerResearch (MICR)

Career Mentoring SessionOrganized by Women in CancerResearch (WICR)

Eighth Annual UndergraduateStudent Caucus and Poster CompetitionOrganized by the AACR ScienceEducation Committee

This exciting session givesundergraduates the opportunity tolearn more about current research in the cancer field, hear frominvestigators about educationalpathways and career development,explore career options in the cancerfield, and compete for monetaryprizes while presenting theirresearch. Undergraduates at alllevels as well as postbaccalaureatestudents are welcome to participate.E-mail [email protected] more information. Visitwww.aacr.org/uscpc to downloadthe registration form.


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Special Program for High School Students: The Conquest of Cancer and theNext Generation of Cancer Researchers

This free, interactive program isdesigned to inspire students topursue careers in cancer researchand the biomedical sciences.Students learn about cancer fromthe experts while interacting withscientists, physicians, and theirpeers. The program includeslectures, tours of the exhibits and

poster areas with mentors, and anetworking lunch. Local studentsand children and/or students ofAACR members and of otherAnnual Meeting registrants arewelcome to register. Visitwww.aacr.org/hs to download the High School Program Registration Form.

Related Career Advancement Sessions

Meet the Research Pioneersessions are organized by theAssociate Member Council (AMC)and are intended for early-careerscientists. These sessions providea special opportunity to meetesteemed researchers in a smallgroup setting to discuss theircareer path and their vision for thefuture of their particular field ofinterest. Last year’s speakersincluded Drs. Beverly A. Teicher,Hans Clevers, Lisa M. Coussens,and Jonathan D. Licht. Sessionswill take place in the AACRAmphitheater in AACRcentral.Limited seating is available on afirst-come, first-served basis.

Career Conversations areinformal networking anddiscussion sessions designed forearly-career scientists. Sessionstake place in the AssociateMember Resource and CareerCenter in AACRcentral and limitedseating is available. Visitwww.aacr.org/AACR2013 forsession updates.

AnnualCareer Fair

The AACR 6th Annual Cancer and BiomedicalResearch Career Fair will be held on Saturday, April 6, 2013. Recruiters from academia, industry,and government will meet and connect withresearchers and clinicians at all career levels.The Career Fair is free to all job seekers.Recruiters will have free access to interviewrooms during the 2013 Career Fair andthroughout the Annual Meeting. Please visitwww.aacr.org/careerfair for more information.

For session updates, visit www.aacr.org/pas.



gUiDEliNES FOR PREPARATiON AND SUBMiSSiON OF ABSTRACTS

Before you submit your abstractonline at www.aacr.org/AACR2013,you must have the following:

1) Web Browser: Microsoft InternetExplorer 7.0 or Higher. The AACROnline Abstract Submission Systemhas been optimized for use with thenewest features only available inInternet Explorer version 7.0.(Download atwww.microsoft.com/windows/ie.)Browsers should be set to enableJavaScript and to accept cookies.Users who need assistance inproperly updating and configuringtheir browsers should contactAbstract Submission CustomerService at (217) 398-1792 [email protected].

2) Sponsor Permission andInformation. Each abstract must besponsored by an Active, Emeritus,Honorary, Associate, or AffilateAACR member. You will be asked toprovide the name or membernumber of the AACR member whohas agreed to sponsor yourabstract; you must secure thepermission of the sponsor beforesubmitting the abstract. Each AACRmember in good standing (duespaid for the current year) maysponsor one abstract. Please keepin mind that as a result of thisrestriction, each abstract submittedmust have a different membersponsor. For details, see the“Abstract Sponsorship Regulations”on page 16 of this Call for Abstracts.

3) Payment Information:Submission Fee. Each abstractsubmitted must be accompanied by

a $60 abstract submission fee. Youwill be asked to provide valid creditcard information to cover paymentof the fee, or you may send a checkto the address provided in thepayment section of the OnlineAbstract Submission System(include the Abstract ControlNumber on your check). Yoursubmission will not be completeuntil payment is verified. Thesubmission fee is nonrefundableregardless of the final disposition ofthe abstract. Receipts may beobtained by contacting the AACR [email protected].

4) Financial Relationships ofCo-Authors. Per ACCMEregulations, the AACR must collectinformation on the financialrelationships of all meetingpresenters and abstract authors.You will be asked to disclose yourfinancial relationships and thefinancial relationships of all of yourco-authors. For more information onfinancial relationships, visitwww.aacr.org/home/scientists/meetings–workshops/cme.aspx.

5) Abstract Category andSubclassification. You must selecta category and subclassification for your abstract. See pages 20-25for details.

6) Chemical Structure Statement.You will be asked to state whetherchemical compounds were used togenerate the data in the abstractand, if so, whether you intend todisclose the chemical structureduring your presentation at themeeting.

What You Need to Submit an Abstract


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AACR Online Abstract Submission System

Authors must submit abstractsfor presentation at the AnnualMeeting 2013 using the AACROnline Abstract SubmissionSystem, which will be availableat www.aacr.org/AACR2013beginning Monday October 1,2012. You can create, modify,and submit abstracts until theNovember 15, 2012, abstractdeadline. Complete instructionson the use of the AACR OnlineAbstract Submission Systemwill be provided on the website.

Abstract Control Number

An Abstract Control Number willbe assigned to each abstractsubmitted online and will belisted on all e-mailcorrespondence regarding theabstract. Please refer to theAbstract Control Number in anyabstract communications.

Length of Abstracts

The combined length of theabstract body, title, and tablesmay not exceed 2,600characters, not including spacesand the author list. Tables countfor 800 characters against thelimit. Submission cannot becompleted for abstracts thatexceed this limit.

Copyright Transfer/Permissionto Record/AbstractPresentation

On behalf of all authors, thecorresponding author mustagree to:

1) Transfer copyright of theabstract to the AACR forpublication;

2) Grant the AACR permission torecord the audio portion (ifany) of the abstractpresentation and to collect allrevenue from subsequentsales; and

3) Confirm that an author willattend the Annual Meeting topresent the abstract.

Abstract Deadline

The deadline for abstractsubmissions is 11:59 p.m. U.S. Eastern Time, Thursday,November 15, 2012. Abstractssubmitted in any form after thedeadline will not be consideredby the Program Committee.

Note: Submitting an abstract forpresentation at the AACRAnnual Meeting 2013 does notconstitute registration for themeeting. Abstract presentersmust register to attend themeeting by using the formenclosed in this publication orby registering online atwww.aacr.org/AACR2013.

The AACR will not beresponsible for the acceptanceand processing of revisedabstracts that are not submittedin compliance with the postedregulations. No changes may bemade in abstracts after theNovember 15, 2012, deadline.

Procedure for Submitting Abstracts




Late-Breaking Abstract Deadline

The deadline for late-breakingabstracts is Monday, January 28,2013. Abstracts detailing highlysignificant and timely findings in anyarea of cancer research that werenot available at the time of theregular abstract deadline will beconsidered by the AACR AnnualMeeting Program Committee forpresentation at the AACR AnnualMeeting 2013. Only those abstractsthat are deemed to be of highscientific priority will be accepted.

A special subcommittee of theProgram Committee will evaluatethe merit of late-breaking abstracts.Each late-breaking abstract must besponsored by an AACR member.Abstract submission fees andsponsorship regulations also applyto late-breaking abstracts.

Deadline for Withdrawal ofAbstracts

The AACR cannot comply with anyrequest for withdrawal of anabstract that will delay thepublication of the Proceedings.However, requests to withdrawabstracts will be accepted throughFriday, January 25, 2013. Requeststo withdraw late-breaking abstractswill be accepted throughWednesday, March 6, 2013.Withdrawal requests must sent bye-mail to [email protected] requests must include

the abstract control number and titleas well as an explanation of thereason for withdrawal.

Presentation of Abstracts at theAACR Annual Meeting

Because the Proceedings of theAACR is intended to represent asummary of all of the abstractpresentations at the AnnualMeeting, every abstract that hasbeen accepted for publication in theProceedings of the AACR must alsobe presented at the meeting.Specifically, the author listed as thepresenter for an abstractsubmission must attend the sessionin which the abstract is scheduledto discuss in detail the researchoutlined in the published abstract,according to the specific guidelinesof the session. If, due to unforeseencircumstances, the designatedpresenter is unavailable to attendthe session to present the abstract,he or she must contact the AACRProgram Development Departmentat (215) 440-9300 [email protected] to designate aco-author to serve as the presenter.If no authors are available to presentthe abstract, the presenter mustwithdraw the abstract immediatelyby contacting the AACR ProgramDevelopment Department.

Failure to comply with theseregulations pertaining to abstractpresentation may result in actionsincluding:

• The withdrawal of the abstractfrom the session

• The removal of the abstract fromthe online Proceedings

• The loss of future sponsorshipprivileges for the sponsor of theabstract

• The loss of future abstractsubmission/authorship privilegesfor the presenter of the abstract

late-Breaking Abstracts


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1. Each abstract submitted for presentationat the AACR Annual Meeting must besponsored by an Active, Emeritus,Honorary, Associate, or Affiliate AACR member.

2. Active, Emeritus, and Honorary membersmay use their sponsorship privilege in oneof two ways: (a) the sponsor may be oneof the authors of the abstract; or (b) thesponsor may use his or her privilege onbehalf of the authors, who may be eithermembers or nonmembers of AACR.

3. An Associate or Affiliate Member in goodstanding may sponsor his or her ownabstract provided that: (a) he or she is thepresenter of the abstract; and (b) anActive, Emeritus, or Honorary Member ingood standing endorses the work. Byendorsing an abstract, a member does notlose his or her own sponsorship privilege.

4. The sponsor must be a member of AACRin good standing. Membership dues musthave been paid through the current yearby the time of the submission of theabstract in order for the member to serveas the sponsor of an abstract for theupcoming Annual Meeting. As Honoraryand Emeritus members are exempt fromthe payment of dues, this regulation doesnot apply to them. Student members arenot eligible to sponsor an abstract.

5. Each member of AACR may sponsor oneabstract for the November 15, 2012,regular deadline and one abstract for theJanuary 28, 2013, late-breaking deadline.(Members must have their 2013 dues paidbefore sponsoring a late-breaking abstract.)

6. Permission to list an Active, Emeritus, orHonorary AACR member as a sponsor orendorser must be obtained prior toselecting the sponsor/endorser in theOnline Abstract Submission System.Individuals listed as sponsors orendorsers of abstracts will receive aconfirmation of sponsorship orendorsement via e-mail or fax. Sponsorsand endorsers are strongly encouraged toreview the confirmation e-mail or fax toensure that the correct abstract title,author, etc., has been indicated.

7. The sponsor is obligated to ascertain thatall authors are aware of and agree to thecontent of the abstract. Sponsorship ofan abstract implies support for the dataand the interpretations contained therein.Individuals who wish to apply for AACRmembership and sponsor their ownabstract must submit their completeapplication for membership no later thanNovember 8, 2012 for regular abstractsor by January 21, 2013, for late-breakingabstracts. Membership questions may bedirected to [email protected].

COMPLIANCE WITH THESEREGULATIONS IS THE RESPONSIBILITYOF THE AUTHORS. Adherence to theserules will be strictly enforced. Violations willresult in the rejection of the abstract by theProgram Committee.


Abstract SponsorshipRegulations


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Disclosure of Chemical Structures

At the time of abstract submission,the submitting author is required tostate whether chemical compoundswere used in the scientific work togenerate the data in the profferedpaper. Chemical compounds aredefined as low-molecular-weight(generally <1000 g/mol) organic orinorganic molecules, peptides, orproteins/nucleic acids co-crystallizedwith low-molecular-weight molecules.

If chemical compounds were used,the corresponding author is furtherrequired to indicate whether thecomplete chemical structures of thecompounds used will be disclosedat the time of presentation at themeeting. The chemical structuresare not required to be included atthe time of abstract submission;rather, an indication of the intent todisclose any such structures at thetime of presentation is required.

The Program Committee will thenevaluate the information provided bythe corresponding author anddetermine the acceptability of theproffered paper for presentation.Those who do not intend to disclosechemical structures may have theirabstracts rejected for participation;however, a limited number of theseabstracts may be accepted forpresentation if deemed to be ofsufficient scientific merit.

Content of Abstracts

Authors who submit abstractsconfirm that they have notpreviously published these data,that they have not previouslypresented them at another largenational annual scientific meeting,and that they are not planning topresent or publish them prior to the dates of the AACR AnnualMeeting 2013.

Each abstract should contain: (a) anintroductory sentence indicating thepurposes of the study; (b) a briefdescription of pertinentexperimental procedures; (c) asummary of the new, unpublisheddata; and (d) a statement of theconclusions.

Authors must accept soleresponsibility for the statements intheir abstracts. Abstracts should becarefully proofread to avoid errors inthe published literature. Americanspelling should be used throughout;for more information regardingAmerican spelling, please refer toScientific Style and Format: TheCSE Manual for Authors, Editors,and Publishers, Seventh Edition(Council of Science Editors, 2006).




The AACR Annual Meeting is thepremier event for presentingcutting-edge cancer research coveringthe spectrum of science from thebench to the clinic. The AnnualMeeting 2012 reinforced the AACR’slong-standing commitment ofhighlighting the best science-basedclinical research by featuring anunprecedented four clinical trialssessions. These sessions were verywell received, often attractingstanding-room-only crowds. Basedupon this success, in 2013 we willcontinue to provide many opportunitiesfor our attendees to feature theirclinical research in Clinical TrialsSymposia, poster sessions, and theClinical Trials in Progress postersession. This Symposium presentationformat, which is detailed below,provides the scientific context in whichthe clinical trials are designed andperformed.

Cutting-edge clinical trials selected fororal presentation will consist ofseparate talks: one featuring the trial

data and one explaining the sciencedriving the clinical trials. In addition toproviding a greater understanding ofthe science, this format providesincreased opportunities forpresentation. Presenters of selectedabstracts will be asked to describe thescience informing the development ofthe novel agent and/or diagnostic andthe clinical trial.

A specially appointed committee willreview and select abstracts focused onpreclinical research and Phase I, II, andIII clinical trials in treatment andprevention to be highlighted asproffered oral presentations. All clinicaltrials-related abstracts submittedwithin the Clinical Research (CL)category and any preclinicalsubcategory that has significant

translational implications will beconsidered for inclusion in this seriesof sessions focused on clinical trials.

Abstracts submitted for both theregular or the late-breaking deadlineswill be considered by the ProgramCommittee. Placeholder abstracts maybe submitted by the January 28late-breaking abstract deadline forclinical trials that only have preliminarydata at the time of submission withfinal results to be submitted by March1, 2013. The process for submitting aplaceholder is detailed on page 19.

Spotlight on Clinical Research


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Placeholder Abstracts for Clinical Trials

In an effort to ensure that the latestand most exciting new data in clinicaltrials is presented at the AnnualMeeting 2013, the AACR hasimplemented a special policy for thesubmission of late-breaking abstractsof clinical trials for which onlypreliminary data are available at thetime of the late-breaking abstractdeadline of January 28, 2013.

To be eligible for consideration, thefollowing guidelines must be strictlyfollowed:

• Abbreviated abstracts must besubmitted by the late-breakingabstract submission deadline ofJanuary 28, 2013, and must alsocomply with the rules specified fortheir submission.

• A placeholder abstract category(PL01: Phase I Clinical Trial Data:Placeholder; PL02: Phase II ClinicalTrial Data: Placeholder, or PL03:Phase III Clinical Trials Data:Placeholder) must be selected in theonline abstract submitter.

• Abstracts must include the followinginformation:

• Objectives of the study

• Methodology

• Preliminary data or an indicationof the type of results anticipated.(This is especially applicable toclinical trials that are about to be closed.)

• Completed abstracts including alldata—that is, Results andConclusions—must be submitted bythe final deadline of March 1, 2013.

The submission of abstracts inaccordance with these guidelinesdoes not guarantee acceptance bythe special subcommittee. Alllate-breaking and placeholderabstracts must be submitted online.Complete instructions for preparingand submitting these abstracts will beavailable in January 2013 atwww.aacr.org/AACR2013.

Clinical Trials in Progress PosterSession

Abstracts submitted to the ClinicalTrials in Progress (CL15) categoryshould summarize promising ongoingtrials that have not yet yielded finalresults. A designated area of theposter hall will be dedicated to thepresentation and discussion ofabstracts accepted to this category.

Press Coverage at AACR Annual Meetings

Growing interest by the general publicin all areas of cancer research,especially patient-centered clinicalinformation, has led to an increase inpress coverage at AACR AnnualMeetings.

• Over 110 press representatives werepresent onsite, and nearly 30attended by teleconference

• More than 21 trillion mediaimpressions resulted from presscoverage of hot topics in 2012, upfrom 3 billion in 2011

• There was press coverage of theOpening Plenary and other PlenarySessions in major media outletsincluding The Wall Street Journal,The New York Times, TimeMagazine, Los Angeles Times, USAToday, NBC Today Show Online,

ABC World News Tonight, CBSEvening News, U.S. News & WorldReport, The Washington Post, CNN,BBC, Nature, Oncology Times, and more

• Major outlets featured extensivepress coverage of clinical trials such as BATTLE and STAR, whichwere presented in major scientificsessions




MCB Molecular and Cellular Biology

MCB1 Cell Growth Signaling Pathways Growth factorsReceptorsCell signalingTumor-stromal cell interactionsCell-cell interactionsCell and tissue kineticsProtein and lipid kinasesProtein and lipid phosphatasesGTPases, their regulators, and effectorsUbiquitin and ubiquitin-like proteinsProtein acetylationProtein traffickingCell polaritySignaling and new technologiesOther

MCB2 Cell Death Transcriptional control of apoptosisCell death receptors/apoptotic signaling pathwaysCaspasesEffectors of apoptosisRegulators of apoptosisEnhancement of apoptosis by chemotherapeutic agents

Survival factorsbcl-2 family proteins: Anti- and proapoptoticAutophagy and cell deathNecrosis and necroptosisOther

MCB3 Molecular Genetics Molecular marker studiesFunctional identification of new cancer genesCloning of cancer genesMolecular cytogeneticsMutation detection methodsOther

MCB4 Oncogenes and Tumor Suppressor Genes Oncogene growth factors and their receptorsTumor suppressor genesCytoplasmic signal transducers (ras, raf, MAPK regulators, apoptosis regulators, etc.)

Nuclear oncoproteins and tumor suppressor genesGenotype/phenotype correlationsOther

MCB5 Gene Regulation and Transcription Factors Gene expressionChromatin structure and functionMechanisms of transcriptionOncogenic transcription factorsPromoters and enhancers of transcriptionProtein-protein interactions in transcriptionfactor function

RNA interferenceTranscriptional control of cell differentiationPosttranscriptional and translational controlRegulation of transcription factor functionOther

Abstract Categories 2013

The 2013 abstract categories, along with their related subcategoriesand subclassifications, are presented for your information in thissection. When you use the Online Abstract Submission System,these options are available for your selection. Authors are asked tochoose the appropriate category, subcategory, and subclassificationthat best describe the scientific content of the abstract and theparticular scientific audience you wish to reach. This information willbe used as a guide by the members of the Program Committee intheir review of abstracts and planning of sessions at the 2013Annual Meeting. Please note that these abstract categories may ormay not be used as Annual Meeting session titles. There is someintentional duplication of topics across categories. Before makingyour selection, please scan the entire list for the most appropriateabstract category, subcategory, and subclassification.


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MCB6 Epigenetics Chromatin structure and functionDNA methylationDNA methylation inhibitorsEpigenetic changes as molecularmarkers of cancer

Gene silencingGenomic imprintingHistone acetylationHistone methylationOther

MCB7 Cell Cycle Control of cell cycle progressionCell cycle checkpointsCyclinsCDKs and CDK inhibitorsMitosisCytokinesisPhosphorylation and proteolysis in cell cycle control

Negative cell cycle regulatorsQuiescenceDNA synthesisTelomeres and telomeraseOther

MCB8 DNA Damage and Repair Gene amplificationNon-homologous end joiningHomologous recombinationTranscription-coupled repairChromosomal structuralalterations/translocations

Genomic instabilityMechanisms of genomic alterationsViral mechanisms affecting DNA damage and repair

Other

MCB9 Metabolism and CancerAutophagySignaling pathways that regulate metabolism

Metabolic pathwaysMitochondrial functionEnergy kineticsMetabolic interactions betweenepithelial and stromal cells

Warburg effectOther

MCB10 Genomics Genomic profiling of tumorsComputational tools and databasesFunctional genomicsHigh-throughput biology Large-scale approaches to cancer gene discovery

Single cell cancer genomicsTumor evolutionOther

MCB11 Bioinformatics and ComputationalMolecular Biology Gene expression profilingSequence analysisNew algorithmsUnique database resourcesMolecular modelingNew software for data analysisMathematical modelingApplication of bioinformatics to cancer biology

Other

MCB12 Innovative Technologies in Cancer Research Tumor microdissection SequencingMicroarraysProteomicsMetabolomicsImagingOther

MCB13 microRNAs and Other Noncoding RNAs miRNA regulation of cancer biologymiRNAs as tumor suppressors/oncogenes

miRNA profiling in cancerEpigenetic control of miRNA expression

Ultraconserved region-derived small RNAs

Noncoding RNAsGenetics of miRNA and/or other noncoding RNAs

miRNA-based diagnosticsmiRNA-based therapeuticsOther

MCB14 Cancer Systems Biology Integrative cancer biologySynthetic biologyNetwork biologyBiological systems engineeringComplex dynamical systemsComputational systems biologySystems modelingControl theoryOther

MCB15 Cellular Stress Responses Oxidative stressAnoikisSenescenceAgingTelomere shorteningHypoxiaUnfolded protein responseOther

TB Tumor Biology

TB1 Cell Culture and Animal Models of Cancer Mouse models of human cancerHuman-in-mouse models of human cancer

3-D and tissue recombinant modelsNoninvasive imaging in animal modelsDevelopmental phenotypes of cancer genes

Model organisms in drug discoveryZebrafish models of cancerOther animal and cell models of cancer

Other

TB2 Stem Cell Biology/Cancer Stem Cells/Developmental Oncobiology Adult stem cellsEmbryonic stem cellsStem cell markersStem-cell-based therapiesCancer stem cellsDevelopmental pathways in cancerOther

TB3 Tumor Adhesion Cell adhesion and extracellular matrixCell-cell adhesionIn vitro models of tumor adhesionReconstituted basement membrane 3-D models

Drug resistanceOther

TB4 Tumor Metastasis Biomarkers of tumor metastasisDetection of occult metastasesEpithelial/mesenchymal transitionExpression profiling of tumor progression and metastasis

Imaging of tumor progression and metastasis

Metastasis and the tumormicroenvironment

Metastasis-promoting genesMetastasis suppressor genesCTC/DTC detection Premetastatic niche Comparisons of the tumor stem cell niche at the primary versus the metastatic site

Other



TB5 Angiogenesis, Vasculogenesis,Microcirculation, and Cellular Microenvironment Angiogenesis inhibitorsEndothelial cell functions in vitro and in vivo

Host-tumor interactionsMolecular mechanisms of angiogenesis

Novel pro- and antiangiogenic factorsTumor microcirculation and the microenvironment

Antiangiogenic kinase inhibitorsMetronomic therapyPericyte biologyResistance to angiogenesis inhibitorsVEGF/VEGF receptorsVasculogenesis Other

TB6 Tumor Microenvironment Immunity and the microenvironment Epigenetic responses to and from the microenvironment

Extracellular matrix and integrinsChemokines in the microenvironmentDrug targets in the microenvironmentGene expression in the microenvironment

Inflammatory cells as regulators of tumor growth

Immune cells in the tumor microenvironment

Proteases and inhibitors in the microenvironment

Organ-specific microenvironmentsRegulators in body fluids (plasma,CSF, ductal secretions)

Tumor-stromal interactionsTumor/wound relationshipsMicrobiomeMechanotransduction (ECM stiffness)Tumor dormancy Tumor-immune system interactionsMicrovessicles/exosomes, including gap junctions

Microenvironment-induced therapeutic resistance

Other

TB7 In Vivo ImagingImaging of molecular and cellular events in tumors and tumor cells

Imaging of molecular and cellular events in the tumor microenvironment

Imaging in animal modelsImaging the immune responseImaging tumor metabolismNew targets for imagingApplication of imaging technology to the clinic

Advanced nanotechnology and imaging

Other

TB8 Pediatric Cancer - Basic Science (See also CL4: Pediatric Cancer -Clinical Investigations.)Preclinical pediatric researchGenetics/genomics/epigenetics of pediatric cancer

Stem cells and tumors of the developing nervous system

Targeting developmental signaling pathways in cancer

Animal models of pediatric diseasePediatric cancer cell death mechanisms and regulation

Pediatric cancer biomarkersOther

TB9 Radiation Biology(See also CL10: Radiation Oncology.)ATM/ATRCell cycle and apoptosis in radiation responses

Cytokines in radiation responseDNA damage and repair and mutagenesis

Molecular modulators of radiation response

Oncogenes and tumor suppressor genes in radiation responses

Photobiology/photodynamic therapyRadiation-induced biochemical alterations

Radiation-induced gene expressionRadiation resistanceRadioprotectors and radiosensitizersRadiation-activated signaling pathways

Other

TB10 Migration and InvasionMigrationInvasionPolarityActin cytoskeletonMicrotubulesAmeboid and mesenchymal migrationCollective migrationModels of migration and invasionGenes that regulate migration and invasion

Other

CG Carcinogenesis

CG1 Carcinogenesis – Chemical, Viral, and Radiation Immune suppression and carcinogenesis

Animal and in vitro models for carcinogenesis

DNA damage and repairMolecular carcinogenesisChemical carcinogenesisEnvironmental carcinogenesisViral-induced transformationHost-virus interactionsHormonal carcinogenesisRadiation carcinogenesis

MutagenesisPredictive assays for carcinogenicityPremalignant lesionsReactive oxygen studies/oxidative stress

Signal transductionToxicologyTumor promotionOther

CH Cancer Chemistry

CH1 Drug Discovery and Design Drug designLead identification Lead optimizationNatural productsChemoinformatics, in silico screening, and computational methods

High-throughput screening (assays and libraries)

Basic and applied nanotechnology and therapeutics

Synthesis, metabolism, and disposition

Drug deliveryOther

CH2 Structural and Chemical Biology Small molecule, protein, and nucleic acid interactions

X-ray and NMR structuresChemical genetics, genomics, and glycomics

Target identification, small molecule probes, and libraries

Nanotechnology in chemical biologyOther

CH3 Proteomics, Metabolomics, andBiological Mass Spectrometry Proteomics and biomarker discoveryProteomics and signaling networksBiological mass spectrometry and systems biology

Other

CH4 Chemical Aspects ofCarcinogenesisNucleic acid damageCarcinogen metabolism and disposition

Oxidative stress and inflammationOther

CH5 Imaging Agents andRadiotherapeuticsImaging agents and radiotherapeuticsOther

CH6 Drug DeliveryBasic and applied nanotechnology and therapeutics

Other


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CL Clinical Research

CL1 Translational Research – MolecularBiology in the Clinic Cytogenetics and clinical molecular genetics

Minimal residual diseaseMolecular classification of tumorsMolecular diagnosticsLaboratory correlates/new agents that target signal transduction pathways, growth factors, and cell cycle progression

Functional and molecular imagingTumor staging: Correlation of clinical and molecular markers

Other

CL2 Phase I Clinical Trials and ClinicalPharmacology(See also ET5: Pharmacology,Pharmacogenetics, andPharmacogenomics.)Clinical drug resistanceBiodistribution/toxicologyPharmacogenetics/genomics and therapeutic responses

PharmacokineticsSurrogates of drug responseMechanism-based and off-target toxicity models

Other

CL3 Phase II and Phase III Adult ClinicalTrials (Organ Site-specific) (See also CL4: Pediatric Cancer -Clinical Investigations; CL5: ClinicalResearch in the Elderly; CL6: ClinicalResearch in Minorities and MedicallyUnderserved Populations; and CL10:Radiation Oncology.) AIDS-related malignanciesBladder cancerBrain and central nervous system cancers

Breast cancerColorectal cancerGastric cancerHead and neck cancerLeukemia and MDSLiver cancerLymphomaLung cancerMelanoma and skin cancerMyelomaOvarian and other gynecological cancers

Pancreatic cancerPeripheral nervous system cancers and endocrine tumors

Prostate and other genitourinary tract cancers

Renal cancerSarcomaThyroid cancerOther

CL4 Pediatric Cancer – ClinicalInvestigations(See also TB8: Pediatric Cancer - BasicScience; and CL3: Phase II andPhase III Adult Clinical Trials.)Pediatric phase I, II, and III clinical trials

Translational studies in childrenDevelopmental therapeutics in pediatric oncology (drug development and discovery)

Pediatric drug toxicity and/or resistance

Pediatric cancer behavioral scienceImmunoRx/transplant studiesLate effects/survivorshipOther

CL5 Clinical Research in the Elderly (See also CL3: Phase II andPhase III Adult Clinical Trials.)Organ site-specific phase I, II, and III clinical trials

Aging, immunity, and cancerOutcomes researchPharmacologic considerations Other

CL6 Clinical Research in Minorities andMedically Underserved Populations(See also CL3: Phase II andPhase III Adult Clinical Trials.)Organ site-specific phase I, II, and III clinical trials

Aging, immunity, and cancerOutcomes researchPharmacologic considerations Other

CL7 Biostatistics in Clinical Trials Design and analysis of clinical trialsNew study designs: Theory, methodology, and modeling

Biostatistical methods in translational studies

Meta-analysisComparative effectiveness research and cost-effective studies

Other

CL8 Ethics in Clinical TrialsEthics in clinical trialsOther

CL9 Clinical Immunology/BiologicalTherapy (See IM2: Cancer Immunotherapy,Preclinical and Clinical.)

CL10 Radiation Oncology(See also TB9: Radiation Biology; and CL3: Phase II and Phase III Adult Clinical Trials.)Modification of radiation sensitivityRadiation resistanceClinical radiotherapeutic studiesCombination therapies/organ site-specific phase I, II, and III clinical trials

Radiation-induced late effects/second cancers

Other

CL11 Clinical Endocrinology(See EN2: Clinical Endocrinology.)

CL12 Supportive Care and SurvivorshipResearch Biology of cell and tissue damageLate effectsInteractions with other comorbiditiesInterventions to reduce neurocognitive dysfunction

Psycho-oncologyTranslational survivorship researchTransdisciplinary survivorship research Supportive care, palliation, and pain management

Outcomes researchOther

CL13 Molecular Biomarkers forDiagnosis, Prognosis, and PredictionDiagnostic/early detection biomarkers Prognostic/metastasis biomarkers Biomarkers predictive of therapeutic benefit

Other

CL14 Regulatory Science Clinical trial design Combination clinical trial strategies Endpoint validationBiomarker validationCodevelopment of therapeutics and diagnostics

Codevelopment of investigational agents

Molecular signatures of response and toxicity

Quantitative data modeling Retrospective analysesPatient-reported outcomesClinical trial accrualToxicology modelsSafety biomarkers and assaysOther

CL15 Clinical Trials in Progress Phase I clinical trialsPhase II clinical trialsPhase III clinical trialsOther



EN Endocrinology

EN1 Molecular and PreclinicalEndocrinology (See also EN2: Clinical Endocrinology.)Growth factors and receptorsHormonal controlHormone signaling and inhibitorsNuclear receptors: Structure and function

Preclinical studies of endocrine-related cancers

Retinoids and receptorsReceptors and signal transductionSteroid hormone receptorsOther

EN2 Clinical Endocrinology (See also ENI: Molecular and Preclinical Endocrinology.)Retinoid-based cancer therapyHormone receptors and diagnosis/prognosis

Hormone synthesis, metabolism, and inhibitors

Neuroendocrine and other endocrine factors

Endocrine-related cancers (breast, ectopic hormone-related cancers, gynecological cancers, prostate/genitourinary cancers)

Other

EP Epidemiology

EP1 Epidemiology/Methodology Alcohol, smoking, and other lifestyle factors

Diet, physical activity, and obesityDescriptive epidemiology, cancer incidence, mortality, clusters, and secular trends

Health disparities researchEnvironmental and occupational epidemiology

Risk prediction models for incidence, prognosis, and/or mortality

Infection and immune factorsPharmacoepidemiologyPsychosocial and behavioral epidemiology

Cancer survivorshipCancer screeningPrimary and secondary intervention studies

Health services and comparative effectiveness research

Statistical and epidemiological methodology

Hormonal and reproductive factorsOther

EP2 Genetic and Molecular Epidemiology Familial and hereditary cancersPathway and candidate gene studies of risk or prognosis

Genome-wide association studies/Post-GWAS studies

Next-generation sequencing in epidemiology studies(whole genome, exome, targeted, or fine-mapping; RNAseq)

Functional studies of genetic variantsGene-gene and gene-environment interactions

Biomarkers of endogenous or exogenous exposures

Biomarkers of risk and prognosisPharmacogenomicsEpigenetic epidemiologyEpidemiology of premalignant conditions

Epidemiology of tumor molecular heterogeneity

Omics technologies in epidemiology studies (gene expression profiling, proteomics, metabolics)

Emerging areas in molecular epidemiology: Microbiome, exposome, other

Novel methods and bioinformatics approaches in molecular epidemiology studies

Other

ET Experimental and Molecular Therapeutics

ET1 Drug Discovery Biochemical modulators of the therapeutic index

Combination chemotherapyDifferentiation therapyNovel assay technologyAntibody technologiesNew targetsNovel drug delivery systemsThe tumor microenvironment in innovative cancer drug development

Other

ET2 Mechanisms of Drug ActionCell cycle mechanisms of anticancer drug action

Cellular responses to anticancer drugsInteractions of new agents with radiation

Role of microenvironment in therapeutic responses

Other

ET3 New Molecular TargetsIdentification of molecular targetsCell death pathways and treatmentFunctional and molecular imaging to assess targeted drug action

Modulation of DNA repairMolecular classification of tumors for diagnostics, prognostics, and therapeutic outcomes

New in vitro and in vivo models for targets

Other

ET4 Drug ResistanceBiochemistry of membrane metabolism and transport

Drug resistance in molecular targeted therapies

Drug transport and metabolismGlutathione metabolismNon-P-glycoprotein multidrug resistance

Novel mechanismsP-glycoprotein structure and functionRegulation of gene expression in drug resistance

Reversal of drug resistanceOther

ET5 Pharmacology, Pharmacogenetics,and Pharmacogenomics(See also CL2: Phase I Clinical Trialsand Clinical Pharmacology.)Cellular pharmacologyMolecular pharmacologyPharmacogenetics and therapeutic response

PharmacogenomicsPharmacokinetics and pharmacodynamics

Preclinical toxicologyOther

ET6 Small Molecule Therapeutic AgentsAlkylating agentsAntifolatesDNA-reactive agentsNovel antitumor agentsPlatinum complexesProteasome inhibitorsHDAC and methyltransferase inhibitorsTopoisomerasesTubulin agentsTyrosine kinase and phosphatase inhibitors

Other


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ET7 Biological Therapeutic Agents(See also IM2: Cancer Immunotherapy,Preclinical and Clinical.)AntireceptorsApoptosis: Therapeutic manipulationGrowth factor receptors and other surface antigens as targets for therapy

Oncogenes, tumor suppressor genes, and gene products as targets for therapy

Protein kinases and phosphatasesas targets for therapy

The role of microenvironment in therapeutic response

Other

ET8 Gene and Vector-Based Therapy Vector systems and targeting strategies

Cell-type-specific expression regulation of suicide genes

Immune modulatorsAntisense moleculesNonbiological delivery systemsProgenitor cell targetingGene therapy and radiation studiesOther

ET9 Preclinical RadiotherapeuticsMolecular targets of radiation response

Normal tissue/cellular stress responses to radiation

Radioprotectors and radiosensitizersModification of radiation sensitivityCombination therapies/organ site-specific phase I, II, and IIIclinical trials

Radiation-induced late effects/second cancers

Other

IM immunology

IM1 Tumor ImmunobiologyTumor antigensInnate immunity to tumorsTumor antigen processing/presentation

Lymphocyte response to tumorsImmune regulationImmune cells in the tumor microenvironment

Tumor-induced immune suppressionLymphocyte traffickingImmunobiology of the tumor microenvironment

Molecular mechanisms of tumor-driven immune suppression

Novel animal modelsInflammation and cancerInflammation and cancer riskInflammation and cancer progressionSystems biology approach to tumor immunity

Other

IM2 Cancer Immunotherapy, Preclinical and Clinical (See also ET7: Biological Therapeutic Agents.)Monoclonal antibodiesVaccines (oncolytic and prophylactic)Cancer biotherapies, including antitumor vaccines

CytokinesAdoptive T-cell transferImmunomodulatory agents and interventions

Modifiers of the tumor microenvironment

Combination therapiesImmune monitoring/clinical correlatesRegulation of immune responses in patients with cancer

Other

PR Prevention Research

PR1 Preclinical Prevention StudiesAnimal models in preventionCellular modelsBiological and biochemical mechanisms in prevention

Biomarkers and intervention studiesMolecular markers in prevention research

Chemoprevention studiesMolecular targets for cancer prevention and development of new agents

Diet and cancerOther

PR2 Clinical Prevention Studies Biomarkers and intervention studiesCancer surveillance and screening studies

Chemoprevention clinical trialsGenomics and proteomics in cancer risk and response assessment

Application of molecular pathology in clinical prevention

Prevention and treatment of premalignant lesions (intraepithelial neoplasia)

Genetic markers as surrogate endpoints in prevention trials

Translational models of chemoprevention

Prevention of second cancersProphylactic surgery in cancer prevention

Recruitment of special populations in clinical prevention trials

International clinical prevention studiesOther

PR3 Behavioral and Social Science inCancer Prevention Research Behavioral science and cancer prevention

Screening and early detectionTobacco: Use, effects, prevention, and cessation

Recruitment/retention/adherence in clinical research

Obesity, diet, physical activity, and energy balance

Quality of life/late effects/survivorshipPrevention behaviors (sun exposure, other)

Cancer communication and decision making

Psycho-neuroimmunology and related factors

Genetic testing and counselingDiffusion and information dissemination

Health disparities researchHealth economics, policy, and outcomes

Other



AACR Membership Categories are described below. Apply formembership online through myAACR at http://myaacr.aacr.orgor download an application atwww.aacr.org/membership.

Special membership rates areavailable for candidates located incountries with emerging economiesas designated by the World Bank.For a complete list of countries withemerging economies, please visitwww.aacr.org/home/membership-/international-interests.aspx.

Contact the AACR MembershipDepartment with any questionsat (215) 440-9300 [email protected].

Active Membership is open toinvestigators worldwide who haveestablished a record of scholarlyactivity resulting in originalpeer-reviewed articles inpublications relevant to cancerresearch and biomedical science.

Affiliate Membership is open toqualified individuals who are healthprofessionals working in support ofcancer research and biomedicalscience; survivors and advocateswho are members of organizationswhose mission includes theadvancement of cancer research;educators; or other professionalswho are interested in and/or makesubstantial contributions to thecancer field.

Associate Membership is open tograduate students; medicalstudents and residents; and clinicaland postdoctoral fellows who areenrolled in education or trainingprograms that could lead to careersin cancer research and the relatedsciences.

Student Membership is open topersons who have manifested aninterest in cancer and the relatedbiomedical sciences and who areenrolled in a program leading to ahigh school diploma or a bachelor’sdegree.

Emeritus Membership is open toexisting Active members who havereached the age of 70 years, whoare disabled, or are retired.

Sustaining Membership is open toorganizations in recognition ofannual payment of dues and othersubstantial contributions in supportof the mission, purposes, andactivities of the Association. Annualdues are determined by thesustaining member level.

Honorary Membership is open todistinguished individuals who havemade extraordinary contributions tothe advancement of cancerresearch either through outstandingpersonal scientific activity orthrough exceptional leadership incancer research. (Candidates forHonorary membership are invitedthrough a special selectionprocess.)

AACR MEMBERShiPCATEgORiES


27

FiNANCiAl SUPPORTFOR ATTENDANCE

AACR Scholar-in-TrainingAwardsApproximately 200 awards of $400to $2,000 (depending on recipient’slocation in U.S. or country ofresidence) are available to firstauthors and presenters ofmeritorious abstracts through thesupport of various foundations andcorporations. Only AACR membersare eligible to apply for these awards.Nonmembers are encouraged toapply for membership.

The AACR Scholar-in-TrainingAwards are open to AACR memberswho are graduate students, medicalstudents and residents, clinicalfellows or equivalent, andpostdoctoral fellows who aretraveling from any country in theworld. To be considered, noapplication is necessary; eligibleindividuals should check theappropriate box in the OnlineAbstract Submission System andsubmit their abstracts by theNovember 15, 2012, deadline.

Through the generosity of itssupporters and grants from theNational Cancer Institute, the AACRis pleased to provide financialsupport to meritorious early-careerscientists residing anywhere in theworld, and also to members ofminority groups residing in theUnited States or Canada that havebeen traditionally underrepresentedin cancer and biomedical researchto assist them in attending theAACR Annual Meeting. Detailedinformation about these awardprograms, including eligibility andselection criteria, can be found byvisiting www.aacr.org/AACR2013and clicking on the FinancialSupport for Attendance link.

Minorities in Cancer Research (MiCR)-Sponsored AwardsMinorities in Cancer Research(MICR) – a membership group withinAACR – is working to increase the

number, participation, visibility, andrecognition of minority scientists incancer research. The AACRMinority-Serving Institution Facultyand Minority Scholar Awards aretwo of several programs sponsoredby MICR in support of its mission.These awards are generouslysupported by the National CancerInstitute Center to Reduce CancerHealth Disparities. To learn more,please visit www.aacr.org/micr orsend an e-mail to [email protected].

AACR Minority-Serving InstitutionFaculty Scholar in CancerResearch: The AACRMinority-Serving Institution FacultyScholar in Cancer Research Awardsare intended to increase thescientific knowledge base of facultymembers at minority-servinginstitutions, to encourage them intheir research, and to assist ininspiring their students to pursuecareers in cancer research. Theseawards are available to full-timefaculty members of minority-servinginstitutions (as defined by the U.S.Department of Education) who arescientists at the level of assistantprofessor or above and who areengaged in meritorious basic,clinical, translational, orepidemiological cancer research.Only citizens or permanentresidents of the United States orCanada may receive one of theseawards. For details or to submit ordownload an application, visitwww.aacr.org/msi. Applicationdeadline: November 30, 2012.

AACR Minority Scholar in CancerResearch: The AACR MinorityScholar in Cancer Research Awardsare intended to enhance theeducation and training of minorityresearchers and increase thevisibility and recognition ofminorities involved in cancerresearch. Eligible scientists arefull-time predoctoral (graduate ormedical) students, medicalresidents, postdoctoral and clinicalfellows, and junior faculty who are

either engaged in cancer researchor have training that could lead tocontributions in the field. Onlycitizens or permanent residents ofthe United States or Canada mayreceive one of these awards. Fordetails or to submit or download anapplication, visit www.aacr.org/msa.Application deadline: November30, 2012.

AACR-Women in Cancer Research (WiCR)Scholar AwardsAACR-WICR Scholar Awards areawarded to members of Women inCancer Research who are full-timescientists-in-training. Graduatestudents, medical students,residents, clinical fellows orequivalent, or postdoctoral fellowswho are presenters of meritoriousscientific papers at the AACRAnnual Meeting are eligible. To learnmore about WICR and this awardprogram, please visitwww.aacr.org/wicr or send ane-mail to [email protected]. Applicationdeadline: November 30, 2012.

AACR-Thomas J. BardosScience Education Awardsfor Undergraduate StudentsIn keeping with the Association’sefforts to promote the educationand training of the next generationof able and dedicated scientists, theAACR is pleased to provideAACR-Thomas J. Bardos ScienceEducation Awards forUndergraduate Students. Thesetravel awards provide third-yearundergraduates with the funds toparticipate in two consecutiveAACR Annual Meetings. To learnmore about this award program,please visit www.aacr.org/bardos or send an e-mail [email protected] deadline: November 30, 2012.



Housing for the AACR Annual Meeting2013 will open at 9:00 a.m. EasternTime on Tuesday, September 25,2012. Please see pages 38-39 of thispublication for a listing of the officialconference hotels. The deadline formaking hotel reservations isWednesday, February 20, 2013. Afterthe deadline, registrants will berequired to make their own housingarrangements. It is strongly suggestedthat room reservations be guaranteedwith a major credit card.

hotel ReservationsYou may reserve your hotel room inone of the following ways:

Online: Visit the AACR AnnualMeeting website atwww.aacr.org/AACR2013 to reserveyour hotel room online. Please notethat you must supply a credit card inorder to reserve a room online. Youwill find descriptions, amenityinformation, and photographs foreach AACR official hotel. Additionally,a map showing the location of allhotels and the Walter E. WashingtonConvention Center is also availableon the AACR Housing website. Visitthe AACR Housing website to getup-to-the-minute availability andreceive immediate confirmation ofyour hotel reservation.

Phone: AACR Housing agents will beavailable to accept reservations aswell as provide information on theAACR official hotels Monday throughFriday from 9:00 a.m. to 9:00 p.m.Eastern Time. You will be required tosupply a credit card if reserving yourhotel room by phone. Once yourreservation is complete, you willreceive immediate confirmation bye-mail or fax. AACR Housing can bereached toll-free in the U.S. andCanada at (888) 381-7166 or forinternational callers at (415)979-2262. When calling AACRHousing be certain to have thefollowing information:

• Arrival and departure dates

• Hotel preferences

• Credit card number

• Your address, phone number, fax number, and e-mail address

• Any special requests

Fax: Complete the Attendee HousingForm found on page 37 and fax it toAACR Housing at (415) 293-4397.When faxing the Attendee HousingForm please be certain to indicate sixchoices. Please allow 24 hours forconfirmation of your reservation. Yourconfirmation will be sent via e-mail ifan e-mail address is provided on theAttendee Housing Form. If no e-mailaddress is provided, yourconfirmation will be faxed. If you donot provide either an e-mail addressor a fax number your confirmationwill be mailed.

Mail: Complete the Attendee Housing Form found on page 37 andmail to the address indicated on theform. Be certain to include either acredit card number or a check toguarantee your reservation. Pleasebe certain to indicate six choices.Your confirmation will be sent viae-mail if an e-mail address isprovided on the Attendee HousingForm. If no e-mail address isprovided, your confirmation will befaxed if a fax number is provided. Ifyou do not provide either an e-mailaddress or a fax number yourconfirmation will be mailed.

guaranteeReservations must be guaranteedwith either a major credit card (Amex,VISA, or MasterCard) or a check inthe amount of $300 per guestroomand $700 per suite. Make checkspayable to Convention ManagementResources, Inc.

Changes andCancellationsChanges and cancellations can be made:

• Online at the AACR Housing website atwww.aacr.org/AACR2013 (for reservations guaranteed with credit card only)

• By faxing your change orcancellation to (415) 293-4397

• By e-mailing your change or cancellation [email protected]

• By calling AACR Housing at (888) 381-7166 or (415) 979-2262

Your credit card will be charged onenight’s room plus tax or your checkwill be forfeited if you cancel yourreservation less than 72 hours beforeyour confirmed arrival date. If you failto arrive on the date confirmed byAACR Housing, your credit card willbe charged one night’s room plus taxor your check will be forfeited. Allsubsequent nights of the reservationwill be cancelled.

Note: It is common practice for hotelsto charge an organization for roomsthat are cancelled or released at thelast minute. The AACR asks that roomreservations and cancellations bemade with care to avoid thesecharges, which will increase the costof the Annual Meeting.

group ReservationsOrganizations wishing to hold a blockof rooms must use the Group HousingForm, which can be obtained byvisiting www.aacr.org/AACR2013 andclicking on the Housing link.Exhibitors may request rooms in theAACR Room Block and must submitan Exhibitor Room Block RequestForm or an Exhibitor Rooming ListForm, which can be accessed fromwww.aacr.org/AACR2013. Pleaseadhere to all rules and regulations tofacilitate processing. Confirmation willbe e-mailed.

hospitality SuitesSuites are for sleeping purposes onlyand may not be used for meetings orevents without prior written permissionfrom AACR. For those types of events,please complete the AACR AffiliateEvent Space Request Form. If youwould like a copy of this form, pleasecontact AACR Housing at (888)381-7166, (415) 979-2262, or viae-mail at [email protected]

Housing Opens Tuesday, September 25, 2012hOUSiNg


29

By Air

Washington, DC, is served bythree major airports: ReaganNational Airport (DCA), DullesInternational Airport (IAD), andBaltimore WashingtonInternational Airport (BWI).Reagan National Airport is 20-45minutes from Walter E.Washington Convention Centerand area downtown hotels. BothIAD and BWI are 45-75 minutesfrom Walter E. WashingtonConvention Center and areadowntown hotels.

Special meeting discounts areavailable on United and AmericanAirlines. Support your associationby using the special promotionalcodes and take advantage of theearly discount savings.Reservations may be madethrough United or American.

You may also book travel throughGant Travel, AACR’s official travelagency. Travel booked throughGant for Annual Meeting 2013 willqualify for a drawing for $500.00in United Airline travel funds touse towards future travel. Drawingwill be based on tickets issuedthrough Gant Travel for the AnnualMeeting and the winner will benotified at the Annual Meeting.Terms and conditions apply.

gant Travel Desk

E-mail: [email protected]

Toll-free: (800) 255-8664; Outside the U.S. and Canada:(630) 227-3873.

Gant is open from 7:30 a.m. to6:00 p.m. U.S. Central Time,Monday through Friday.

A $25 fee applies foragent-assisted reservations. Bookonline for one low fee of $7.

United offers discounts from 2%to 10% off applicable fares.Discounts apply on United Airlinesand flights operated by United orother airlines branded UnitedExpress, Lufthansa, and AllNippon Airways. Provide Z-code:ZNG4 and Agreement Code:559683. Reservations may bebooked through Gant or Unitedvia www.united.com. Unitedreservations can be reached at(800) 521-4041. A fee applies forphone reservations only. Termsand conditions apply.

Save 9% off American’s lowestapplicable fares when you bookand ticket 60 days or more inadvance (agent-assisted only viaGant or American). Book onlineand you will receive a 5%discount on applicable publishedfares via www.aa.com. Providecode: A1533BU. Discounts applyon American, American Eagle,AmericanConnections, andoneworld Alliance Partners only.American reservations can bereached at (800) 433-1790, and afee applies for phonereservations. Terms andconditions apply.

By Train

Amtrak offers a 10% discount offthe best available rail fare toWashington, DC, between April 3, 2013 and April 13, 2013.To book your reservation, callAmtrak at (800) 872-7245 orcontact your local travel agent.Convention travel cannot bebooked via Internet. Please besure to refer to Convention FareCode X16L-953 when makingyour reservation. This offer is notvalid on the Auto Train and AcelaService. Fare is valid on AmtrakRegional for all departures sevendays a week, except for holiday

blackouts. Offer valid with Sleepers,Business Class, or First Class seatswith payment of the full applicableaccommodation charges.

ground Transportation

The AACR has contracted withWashington Flyer Super Shuttle tooffer shuttle service betweenDCA, IAD, BWI, and the Walter E. Washington ConventionCenter and convention hotelsduring the meeting. For airportshuttle service information andreservations, call 1 (800) BLUEVAN or 1 (800) 258-3826 andmention code AACR1 to thereservation agent to receive 5%off a round-trip transfer. Fulldetails on how to reserve theWashington Flyer Super Shuttle are available at:http://groups.supershuttle.com/aacr.html. To avoid wait time andreceive the discount, advancereservations are required.

Public Transportation: The Metroand other regional train and businformation can be obtained byvisiting the WashingtonMetropolitan Area Transit Authorityat http://www.wmata.com.

Assistance forinternational Travelers

An official letter of invitation isavailable through the onlineregistration system. Contact theAmerican Consulate in yourcountry to review the currentregulations for travel to the UnitedStates. Please begin the visaapplication process as early aspossible. Information is availableon the U.S. Department of Statewebsite at www.travel.state.gov.You may also contact the AACR at (215) 440-9300 [email protected] with questions.

TRAvEl


AACR Membership Centers

The AACR Membership Centersprovide a place where members canobtain information regarding theirmembership, join Associationgroups within AACR, update contactinformation, pay annual dues,transfer categories of membership,and become familiar with newmembership services. Nonmembersare encouraged to visit theMembership Center to submit anapplication for membership. AACR is also eager to support theexchange of knowledge andresearch with investigators who are located in countries withemerging economies. (Significantlyreduced membership dues areavailable for these investigators.)Visit the Membership Centerslocated in AACRcentral and theRegistration area to learn moreabout these and other opportunitiesavailable through AACR.

MiCR Networking and Resource Center

The Minorities in Cancer Research(MICR) Networking and ResourceCenter, located in AACRcentral,hosts exciting meet-and-greetopportunities with prominentinvestigators and provides meetingattendees with a comfortable andsocial environment for networkingone-on-one and in small groups. AllMICR members and Annual Meetingregistrants are encouraged to visitthe MICR Networking and ResourceCenter to learn about AACR andMICR programs, awards, funding,and more.

WiCR Networking and Resource Center

The Women in Cancer Research(WICR) Networking and ResourceCenter, located in AACRcentral,hosts an exciting meet-and-greetopportunity with prominent

investigators and provides meetingattendees with a comfortable andsocial environment for networking.All WICR members and AnnualMeeting registrants are encouragedto visit the WICR Networking andResource Center to learn aboutAACR and WICR programs, awards,funding, and more.

Meet the Mentor: Undergraduate Focus

The AACR Science EducationCommittee is pleased to present aseries of informal lectures aimedspecifically towards undergraduatestudents presented by outstandinginvestigators. Discussion topicsinclude, but are not limited to,guidance on professionaldevelopment, advice on careerpaths, and the pursuit of a career incancer research. These interactiveand informative sessions will takeplace in the Amphitheater located inAACRcentral.


Whether you're catching up on e-mail in theInternet Café or networking with colleagues inone of several resource rooms, you'll findAACRcentral to be an integral part of your AnnualMeeting experience. Located in the heart of theExhibit Hall, AACRcentral brings togethervaluable services and resources for the benefit ofAnnual Meeting attendees. While you're there, besure to stop by the AACR exhibit booth to speakwith knowledgeable AACR staff, learn moreabout our programs and events, become amember, or pick up one of our acclaimed journals.

AACRcentral


31

Associate MemberResource and Career Center

The Associate Member Resourceand Career Center, organized by theAssociate Member Council (AMC), isopen to graduate students, medicalstudents and residents, andpostdoctoral and clinical fellowsregardless of membership status.The Center provides a place forearly-career scientists to connectwith colleagues; plan their time atthe meeting; and learn aboutfunding, employment, and fellowshipopportunities. Attendees can alsoparticipate in Career Conversationssessions, informal networking anddiscussion sessions designed forearly-career scientists. Limitedseating is available on a first-come,first-served basis. Visitwww.aacr.org/AACR2013 forsession updates. Scholar-in-TrainingAwardees can also pick up theirchecks and welcome packet at this location.

AACR Amphitheater

The AACR Amphitheater hosts avariety of sessions, including Meetthe AACR President; Meet the AACRCEO; Meet the Mentor, organized bythe Science Education Committeefor undergraduate students; and theMeet the Research Pioneer sessionsorganized by the Associate MemberCouncil (AMC). These sessionsprovide a special opportunity tomeet esteemed researchers in asmall group setting to discuss theircareer path and their vision for thefuture of their field. Last year’sspeakers included Drs. Beverly A.Teicher, Hans Clevers, Lisa M.Coussens, and Jonathan D. Licht.Limited seating is available on afirst-come, first-served basis for all programs.

AACR CancerCareers.orgCenter

The CancerCareers.org Center iswhere researchers and clinicians atall career levels come for the rightopportunities and where recruitersfrom academia, industry, andgovernment can meet and recruitthe right talent. Visit the Center atthe 2013 Annual Meeting or onlineanytime at www.CancerCareers.org.


The AACR is dedicated to bringingyou the latest innovations in mobiletechnology to enhance and facilitateyour Annual Meeting experience. Weare pleased to offer the followingtechnology products and services.

Free Wireless Internet Access.Wireless internet access will beavailable to meeting attendees in theWalter E. Washington ConventionCenter.

Online Proceedings/ItineraryPlanner. Search all Annual Meetingpresentations (including all profferedabstracts) by author/speaker, titleword, and keyword and create apersonal itinerary for the meeting.

Mobile Itineraries. Personalitineraries created in the ItineraryPlanner can be exported as aniCalendar file into users’ personalOutlook, Google Calendar, or AppleiCal applications. Itineraries are alsoavailable as an HTML page that canbe e-mailed to users’ smartphones(iPhone, Palm Pre/Centro, HTCTouch Pro, and BlackberryCurve/Storm/Pearl) for use during themeeting.

Mobile Proceedings. The digitaledition of the Proceedings willcontain abstracts of all profferedpapers accepted for presentation aswell as the extended abstractssubmitted by invited speakers. Theabstracts will be available in mobiand e-pub file formats for downloadto the Amazon Kindle, iPad, iPhone,iPod Touch, Sony Reader, and theBarnes & Noble Nook.

Proceedings CD-ROM. Search andbrowse all Annual Meeting abstractpresentations by author/speaker, titleword, keyword, and session type.

Please note that, beginning in 2013,the Annual Meeting CD-ROM willonly be available for purchase. Toobtain a copy of the CD-ROM at themeeting, you must check theappropriate box on the registrationform. (Order by February 6, 2013 toguarantee availability.) The cost of theCD-ROM will be $10.

Annual Meeting 2013 ProgramGuide App. Carry the Annual Meetingwith you wherever you go—with orwithout a network connection. TheProgram Guide App is available innative versions to serve users ofiPhone, iPad, and Android devices(including the Kindle Fire) as well as abrowser-based version for use onmost web-enabled smartphones and tablets.

The Program Guide App offers thefollowing features:

• Native Storage. Once downloaded,all App content and functionality isstored natively on your Apple orAndroid device and can beaccessed without an Internetconnection. (Note: The browser-based version of the App is amobile-optimized website andrequires an Internet connection.The performance of the mobile webversion will depend on the speedand strength of the user's Internetconnection.)

• Meeting Abstracts. The full text ofmore than 6,100 abstracts will bestored natively in the Apple andAndroid Apps, so you can accessthe poster session andminisymposium presentationswherever you are.

• Happening Soon. Have a freemoment? Get a quick list of the

sessions starting in the next 30minutes while at the meeting.

• Personal Itinerary. Sessions can bebookmarked and saved to youritinerary folder to create a personalschedule for the meeting. You canalso sync your itinerary to your localdevice calendar.

• Search/Browse. You can search orbrowse Annual Meeting sessionsby type, title, and topic. You canalso search or browse the completelist of invited and profferedpresentations—including the fulltext of abstract presentations—bykeyword or presenter. AnnualMeeting exhibitors can also besearched or browsed by companyname or product category.

• Maps. Detailed floor plans of allAnnual Meeting venues—includingthe complete exhibit hall and posterarea map as well as the hotel andbus route map—are stored nativelyin the App for easy browsing.

NEW IN 2013: From the SessionView, you can open a floor planthat highlights the assignedsession room for easier navigation.

• Attendee Information. Look up the locations and hours ofcritical Annual Meeting services,including shuttle bus routes, theInternet Café, the coat and bagcheck, and the child care/nursingmothers room.

Annual Meeting 2013 Webcast.Complete Scientific SessionsAvailable Online. As in previousyears, the AACR will make theOpening Ceremony, the majorPlenary Sessions, and the AwardLectures available free as streamingvideo. In addition, attendees can


MOBilE TEChNOlOgY ATThE ANNUAl MEETiNg


33

purchase exclusive online streamingaccess to the audio and slides of allscientific sessions presented at theAACR Annual Meeting 2013.*

The Annual Meeting Webcast includesthe following features:

• Presentation slides synchronizedwith recorded audio presentations

• Speakers’ mouse movementscaptured and included in playback

• Available on compatible mobiledevices and smartphones such asiPad, iPod Touch, iPhone, andAndroid devices

• Presentations searchable by session title, presentation title, andspeaker name

• Exclusive access to online content for15 months after the Annual Meeting

Purchase individual access to theAACR Annual Meeting 2013 byselecting the Premium Package atregistration and get the lowest rates.See page 36 for pricing.

*Participation in the AACR AnnualMeeting Webcast is left to thediscretion of each speaker. As aresult, some presentations may not beavailable for webcast, and somewebcast presentations may not

include all slides. Access is grantedvia individual username andpassword.

AACR Video App. Audio recordingsof all AACR press conferences arenow available for free through theAACR Video app. Download the appnow (available for the iPhone, iPad,and Android devices) to learn aboutrecent developments and discoveriesin basic and translational cancerresearch. Learn more at:www.aacr.org/videoapp.

ANNUAl MEETiNg PRiNT PUBliCATiONS

Final Program

NEW IN 2013: Available by Request Only

The Annual Meeting Final Program willcontain the dates, times, titles,speakers, locations, and descriptionsfor all presentations and will beprovided to all registrants at theAnnual Meeting. At the request ofAnnual Meeting attendees who preferto use the online Itinerary Planner orthe Program Guide App to navigatethe Annual Meeting, the AACR isoffering the Print Program by requestonly in 2013. There is no charge forthe Print Program, but in order toreceive a copy you must request it bychecking the appropriate box on theregistration form. To ensure that youreceive your print Program, you mustregister for the meeting by February11, 2013. Additional print copies willbe available for late registrants on afirst-come, first-served basis.

Proceedings

The Proceedings of the AACR willcontain abstracts of all profferedpapers accepted for presentation aswell as the extended abstractssubmitted by invited speakers. Toobtain a copy of the print Proceedingsbefore or at the meeting, you mustorder by February 6, 2013, and checkthe appropriate box on theregistration form. The cost is $55 for acopy of the Proceedings to be mailedto you (approximately four weeksbefore the meeting) or $40 for a copyto be picked up at the meeting. Afterthe Annual Meeting, remaining copieswill be available for $75 plus shipping.

Education Book

The Education Book will containstate-of-the-art overviews fromspeakers in the Educational Sessionsand Methods Workshops taking placeon Saturday, April 6. It will beavailable free online athttp://educationbook.aacrjournals.orgafter the meeting, but attendees canalso obtain a free print copy onsite byrequest. Check the appropriate boxon the registration form to reserve acopy.


AACR ANNUAL MEETING 2013 abstract submission Deadline: november 15, 2012 34

Three Convenient Ways to Register:

Online: Visit www.aacr.org/AACR2013 and click on thelink for online registration.

Fax: Complete the AACR Official Registration Form on pages 35-36 and fax it to (708) 344-4444.

Mail: Complete the AACR Official Registration Form on pages 35-36 and mail it to:AACR Annual Meeting 2013CompuSystemsP.O. Box 6271 • Broadview, IL 60155-6271

PaymentsRegistration forms submitted without full payment cannotbe processed and will be returned. Government or otherpurchase orders cannot be accepted. All fees must be paidin U.S. currency drawn on a U.S. bank. Please note thatpaying the abstract submission fee does not constituteregistration for the meeting.

Cancellation/RefundRequest for refunds must be made in writing to the AACR.There will be a $75 processing fee applied to refundsrequested by March 1, 2013. No refunds can be made after March 1.

Onsite RegistrationRegistration will open on Friday, April 5, at the Walter E.Washington Convention Center. Advance registrants mayalso pick up their materials at the Renaissance Washingtonand Grand Hyatt Washington, April 5-7.

Friday, April 5 3:00 p.m.-7:00 p.m.Saturday, April 6 7:00 a.m.-5:00 p.m.Sunday, April 7 6:30 a.m.-5:00 p.m.Monday, April 8 6:30 a.m.-5:00 p.m.Tuesday, April 9 6:30 a.m.-5:00 p.m.Wednesday, April 10 6:30 a.m.-12:00 p.m.

Eligibility for Registration at AACR Member RatesIndividuals interested in registering at the early registrationrate must submit membership applications no later thanDecember 14, 2012. Individuals who are interested injoining the AACR and registering at the advance memberrate must submit membership applications no later thanJanuary 31, 2013. Only individuals who are listed on themembership rolls as of March 5, 2013, will be accorded theprivilege of registering for the AACR Annual Meeting 2013at the member rates noted on the registration form in thispublication. If upon review of membership application acandidate is deemed ineligible for the membershipcategory to which he or she has applied, then the

candidate will need to register in advance at thenonmember rate.

Spouse/Guest RegistrationA special reduced $50 Spouse/Guest fee is available forsocial activities and entry to the exhibits and poster areaonly. Spouse/guest registration does not admit individualsto the scientific sessions outside the Exhibit Hall.Arrangements for spouses/guests to attend a singlescientific session can be made at the Onsite RegistrationDesk. Please note that the spouse/guest registration fee isnot available to scientists in the cancer field.

CredentialsAll advance registrants will receive an Express BadgePickup confirmation via e-mail approximately one weekprior to the start of the conference. Please bring this noticewith you to the AACR Annual Meeting 2013 in Washingtonand you may proceed to the Advance Registration countersfor fast pick up of your registration credentials. Your badgewill provide you with access to the scientific sessions aswell as the exhibit floor.

Group RegistrationsAll group registrations (15 or more people) can be sent bymail, fax, or e-mail to:

Group Registration/AACR Annual Meeting 2013CompuSystemsP.O. Box 6271 • Broadview, IL 60155-6271Attn: Lisa ScarbroughFax: (708) 344-4444E-mail: [email protected]

Group registration forms and guidelines can be found atwww.aacr.org/AACR2013. Group registrations must includehousing forms for each registrant within the AACR groupblock. Group registrations will not be processed without anAACR Group Housing Form or notification of location ofhousing outside of the AACR block. Travel agencies or anythird parties must include registration forms that arecompletely filled out with each registrant’s membershipstatus, mailing address, telephone, fax, and e-mail address.All changes in group registrations must be submitted inwriting prior to March 19, 2013. If these changes alter thetotal amount due for the group, a reconciliation of theamount due must be made with CompuSystems no laterthan March 23, 2013. Registration materials forpreregistered groups will be available for pickup atpreassigned times on Friday, April 5, 2013, at theregistration counters at the Walter E. WashingtonConvention Center.

RegistRation Advance Registration opens September 27, 2012

Early Registration deadline December 21, 2012

Advance Registration deadline February 11, 2013

Registration deadline to receive Proceedings by mail February 6, 2013

Deadline for cancellation to receive registration refund,

less processing fee of $75 March 1, 2013

Registrant information

Is this a new address that should be updated in the AACR database?q Yes q NoAre you an AACR Member? q No q Yes Membership # ____________

q Dr.q Mr.q Ms.

Degree (check all that apply): q M.D. q Ph.D. q Pharm.D. q D.Sc. q Other (specify) __________________

Last/Family Name First Name/Middle Initial

Position/Title

Department/Division

Institution/Company

Street Address (Note: Meeting publications cannot be delivered to a P.O. box.)

City State or Province Zip/Postal Code

Country (if not U.S.)

Telephone Fax

E-mail

Assistant’s Name

Assistant’s E-mail

Spouse/Guest name, if registering

q Check this box if you require special accommodations to fully participate in the meeting. Describe briefly below:

_____________________________________________________

_____________________________________________________

AACR Career fair – Saturday, April 6See page 11 for details.

q Yes, I plan to attend. q No, I do not plan to attend.

16th Annual grant Writing WorkshopSaturday, April 6, 12:00 p.m.-5:00 p.m.

Preregistration for this annual five-hour session, aimed towardsgraduate students, medical students and residents, and clinical andpostdoctoral fellows with limited or no grant writing experience, isstrongly encouraged. (Please check the appropriate box under OtherProducts and Services.) See page 10 for details.

q AACR MEMBERS $45q NONMEMBERS $95

Nonmember Predoctoral Student SectionThis section must be completed if you wish to register as anonmember predoctoral student. Forms without certification will notbe processed.

NONMEMBER PREDOCTORAL STUDENT CERTIFICATION

“I certify that the above named student is presently enrolled at thisuniversity and working toward a doctoral degree in a field related tocancer research.”

Name (Registrar, Dean or Dept. Head)

Signature (Registrar, Dean or Dept. Head)

Title

University

AACR foundation for the Prevention and Cure of Cancer*I would like to make a tax-deductible gift to support the work andmission of the AACR.

q $10 q $25 q $50 q $100*See other side of this form to add to registration total.

Additional Registrant information(Required Fields)

Primary Field of Research (please check only one):

q Behavioral Scienceq Biochemistry and Biophysicsq Biostatistics/Bioinformaticsq Carcinogenesisq Cellular Biologyq Chemistryq Clinical Research/Trialsq Computational Biologyq Endocrinologyq Epidemiologyq Other (please specify)______________________________________

Work Setting (please check only one):

q Academiaq Association/Professional Org.q Foundation/

Advocacy Organizationq Governmentq Hospital/Clinicq Other (please specify)______________________________________

Scientific Research Focus: q Basic q Translational q Clinicalq Epidemiological q Behavioral Science

Race or Ethnic Background (check only one):

q Caucasian q African American or Black q Hispanic or Latino q Asian q Native American q Alaskan Native q Native Hawaiian/Pacific Islander q Other

Gender: q Male q Female

Information concerning gender and ethnic background is requestedonly to enable the AACR to ensure that its programs are serving allmembers of its diverse cancer research community.

q AACR will add you to our e-mail list for conference information. Check here if you do not want your e-mail address added to our list.

q Genetics and Genomicsq Immunologyq Molecular Biologyq Preclinical Pharmacology

and Experimental/Molecular Therapeutics

q Prevention Researchq Research Administration/

Business Developmentq Virology

q Industry/Private Sectorq NCI Designated Cancer Centerq Nonprofit Research Centerq Pressq Private Practiceq Vendor

AACR OffiCiAl RegiStRAtiON fORm2013To register online, visit www.aacr.org/AACR2013.

Please print or type on both sides of this form



Proceedings of the AACR and Print Program Options

Print Proceedings. The Proceedings and the Itinerary Planner willbe available free online approximately 1 month prior to the meeting.Registrants who wish to purchase a print Proceedings must checkthe appropriate box under Other Products and Services. Registrantscan pick up a copy of the print Proceedings onsite at a cost of $40;alternatively, registrants in the U.S. can have a copy of the printProceedings mailed to them at a cost of $55 (mailed copies must beordered by February 6, 2013).

NEW: CD-ROM Proceedings Available for Purchase. Beginning in2013, the Annual Meeting Proceedings on CD-ROM will only beavailable for purchase. To obtain a copy of the CD-ROM at themeeting, you must check the appropriate box under Other Productsand Services. (Order by February 6, 2013 to guarantee availability.)The cost of the CD-ROM will be $10.

NEW: Print Program Available by Request Only. Annual Meetingprogram information is freely available through the online ItineraryPlanner, the Program Guide App, and the printed Pocket Calendar.The options below refer to the complete printed Program(approximately 680 pages):

q I do not want to receive a printed Programq I will use the printed Program and plan to pick up a copy onsite.

AACR education Book

The AACR Education Book will be available free online in May 2013(see page 33 of this publication). Print copies will also be availablefree onsite. Quantities are limited and are available on a first-come,first-served basis. Please select only ONE:q I will use the online Education Book and do not plan to pick up a

printed copy.q I plan to pick up a print copy of the Education Book

at the meeting.

Other Products and Servicesq Grant Writing Workshop $_____ $_____ $_____

q Mail copy of printed Proceedingswithin U.S. (MP)† $ 55 $ 55 $ 55

q Pick up copy of printed Proceedingsat Annual Meeting (PP)† $ 40 $ 40 $ 40

q Proceedings on CD-ROM (CDP)† $ 10 $ 10 $ 10

q Tax-deductible gift to AACR Foundation(from other side of form) $_____ $_____ $_____

SUBTOTAL $_____ $_____ $_____†Must be ordered by February 6, 2013 to guarantee availability. Mailed print Proceedingsavailable only to registrants in the U.S.

SUBTOTAL FROMREGISTRATION CATEGORIES ABOVE $_____ $_____ $_____

TOTAL ENCLOSED OR CHARGED $_____ $_____ $_____

method of Payment

q Check or money order enclosed, payable to American Association for Cancer Research, in U.S. currency, drawn on a U.S. bank.

q VISA q MasterCard q American Express

Card Number Expiration Date

Signature

Return by Mail: AACR Annual Meeting 2013CompuSystemsP.O. Box 6271 • Broadview, IL 60155-6271

Fax: (708) 344-4444Courier Delivery: AACR Annual Meeting 2013

2805 S. 25th Ave. • Broadview, IL 60155

AACR Annual meeting Registration Categories

AACR OffiCiAl RegiStRAtiON fORm2013

Please print or type on both sides of this form. Forms without payment will not be processed.

PREMIUM PACKAGE(Includes full individual access to the Annual Meeting 2013Webcast; see page 32 for details.) By Dec. 22- Feb. 12 Dec. 21 Feb. 11 & AfterMEMBER RATESq Active Member (MEM)* $ 609 $ 689 $ 804q Associate Member (MAS)* $ 414 $ 439 $ 519q Affiliate Member (AFM)* $ 509 $ 544 $ 629q Student Member (STU)* $ 179 $ 184 $ 194q Emeritus Member (EMM) $ 194 $ 204 $ 214

NONMEMBER RATESq Nonprofit (NNP) $ 984 $1,064 $1,189q Industry (NIN) $1,154 $1,224 $1,349q Predoctoral Student (NPR) $ 564 $ 589 $ 669

SUBTOTAL $_____ $_____ $_____

*Refer to page 26 for membership application submission deadlines toreceive member registration rates.

STANDARD PACKAGE(Does not include webcast access.)

By Dec. 22- Feb. 12 Dec. 21 Feb. 11 & AfterMEMBER RATESq Active Member (MEM)* $ 510 $ 590 $ 705q Associate Member (MAS)* $ 315 $ 340 $ 420q Affiliate Member (AFM)* $ 410 $ 445 $ 530q Student Member (STU)* $ 80 $ 85 $ 95q Emeritus Member (EMM) $ 95 $ 105 $ 115

NONMEMBER RATESq Nonprofit (NNP) $ 835 $ 915 $1,040q Industry (NIN) $ 955 $1,025 $1,150q Predoctoral Student (NPR) $ 415 $ 440 $ 520q Spouse/Guest (SPO) $ 50 $ 50 $ 50

(social activities and exhibits only)

SUBTOTAL $_____ $_____ $_____

37

AACR OFFiCiAl hOUSiNg FORM 2013

To book your hotel reservation online, visit www.aacr.org/AACR2013.

hotel confirmations should be:

q�E-mailed q Mailed q Faxed to: _____________________________

(Please type or print clearly)

Last/Family Name First Name/Middle Initial

Organization

Street Address

City State or Province Zip/Postal Code

Country (if not U.S.)

Telephone Fax

E-mail

Mobile

Room Occupants

Last/Family Name

First Name

Share with (list all occupants if applicable)

hotel Preferences

(Please fill in all six choices):

Hotel requests will be honored on a first-come, first-served,space-available basis. Submit your request as soon as possible forthe best chance of receiving one of your six choices. See page 38 for choices.

1. ____________________________________________________________

2. ____________________________________________________________

3. ____________________________________________________________

4. ____________________________________________________________

5. ____________________________________________________________

6. ____________________________________________________________

If you are a member of a Hotel Frequent Guest Program and wouldlike to receive appropriate credit, please indicate the hotel chain andnumber below:

Hotel Chain

Membership Number

Arrival, Departure, and Room Type

Arrival Date Departure Date

Room Type:q��Single (1 bed/1person) q Double (1 bed/2 people)q��Double/Double (2 beds/2 people) q Triple (2 beds/3 people)q��Quad (2 beds/4 people)q��Suite (If checked, an AACR Housing consultant will contact you.)

Bed type, smoking requests, and other preferences will be on arequest basis only. All requests are forwarded to the hotel for theirconsideration, and are not confirmed prior to check-in.

q��Non-smoking q Smoking

Special Needs (specify): _______________________________

_____________________________________________________

guarantee information

(No reservation will be processed without a guarantee.)

All reservations must be guaranteed with a valid credit card or acheck in the amount of $300 for a guestroom and $700 for a suite.

q��Enclosed is my check (U.S. funds) payable to Convention Management Resources Inc. Check # ______________________

q VISA q MasterCard q American Express

Credit Card Number Exp. Date

Name on Card

Signature of Cardholder

Cancellation

You may cancel your reservation at least 72 hours prior to your arrivaldate. You will be charged a penalty if your reservation is cancelledwith less than 72 hours notice.

Don’t be a no-show!

If you fail to arrive at your reserved hotel on your confirmed arrivaldate, you will lose your room for all nights of your reservation and youwill be charged a no-show fee. Please contact AACR Housing if youwish to change your arrival/departure dates.

Mail to:

AACR Housing: Annual Meeting 201333 New Montgomery, Suite 1100San Francisco, CA 94105

Fax: (415) 293-4397To speak to a Housing Representative call:(888) 381-7166 (U.S. & Canada) or (415) 979-2262;Monday-Friday 9:00 a.m.-9:00 p.m., Eastern Time


1 Grand Hyatt Washington, DC $305/$305 $330/$355 Y 0.6 miles Y Y No charge $10.00 Indoor 3 1 6:00 a.m.- N $30.00 $40.00 1000 H Street NW 1:00 a.m.

2 Renaissance Washington, DC $305/$305 $325/$345 Y 0.2 miles Y Y No charge No charge N 2 2 6:00 a.m.- N $33.00 $40.00 999 9th Street NW 1:00 a.m.

3 Comfort Inn $179/$179 $189/$189 Y 0.4 miles Y Y No charge No charge N N N N C* N $30.00 Convention Center1201 13th Street NW

4 Embassy Suites DC $279/$279 $304/$329 N 0.4 miles Y Y No charge No charge Indoor 1 1 11:00 a.m.- A** N $35.00 Convention Center 12:00 a.m.900 10th Street NW

5 Four Points by Sheraton $269/$269 $289/$309 Y 0.4 miles Y Y No charge No charge Indoor 1 1 6:00 a.m.- N N $38.00 Washington, DC Downtown 11:00 p.m.1201 K Street NW

6 Hampton Inn Washington $259/$259 $269/$279 Y 0.2 miles Y Y No charge No charge Indoor N 1 N A** N $34.00 Convention Center901 6th Street NW

7 Henley Park Hotel $269/$269 N/A / N/A Y 0.1 miles Y Y No charge No charge N 1 1 24 hrs. N N $33.00 926 Massachusetts Avenue NW

8 Hotel Monaco $289/$289 N/A / N/A Y 0.7 miles Y Y No charge No charge N 1 1 24 hrs. N N $40.00 Washington, DC700 F Street NW

9 Washington Marriott at $295/$295 $315/$335 Y 0.6 miles Y Y No charge No charge Indoor 1 1 6:00 a.m.- N N $47.20 Metro Center 12:00 a.m.775 12th Street NW

10 Morrison-Clark Inn $245/$245 N/A / N/A Y 0.3 miles Y Y No charge No charge N 1 1 7:00 a.m.- N N $33.00 1015 L Street NW 10:00 a.m.

5:00 p.m.- 11:00 p.m.

11 Donovan House, $289/$289 $319/$349 Y 0.5 miles Y Y No charge No charge Outdoor 1 1 6:00 a.m.- N N $42.00 a Kimpton Hotel 10:00 a.m.1155 14th Street NW 12:00 p.m.-

2:00 p.m.5:00 p.m.-10:00 p.m.

12 Hamilton Crowne Plaza $272/$272 $292/$292 Y 0.5 miles Y Y No charge No charge N 1 1 6:00 a.m.- N N $38.00 1001 14th Street NW 11:00 p.m.

13 Residence Inn $259/$259 $279/ N/A Y 0.5 miles Y Y No charge No charge N N N N A** N $28.00 Washington, DC/Vermont Avenue1199 Vermont Avenue NW

14 The Madison $259/$259 $289/$319 Y 0.7 miles Y Y No charge No charge N 1 1 6:00 a.m.- N N $40.00 1177 15th Street NW 11:00 p.m.

15 Washington Plaza Hotel $233/$233 $253/ N/A Y 1.3 miles Y Y No charge No charge Outdoor 1 1 N N $25.00 $30.00 10 Thomas Circle NW

16 JW Marriott Washington, DC $319/$319 $339/$359 Y 1 mile Y Y No charge No charge Indoor 3 1 24 hrs. N N $47.20 1331 Pennsylvania Avenue NW

17 Beacon Hotel & $242/$242 $262/ N/A Y 0.9 miles Y Y No charge No charge N 1 2 7:00 a.m.- N N $33.00 Corporate Quarters 10:00 p.m.1615 Rhode Island Avenue NW

18 DoubleTree by Hilton Hotel $232/$232 $252/$272 Y 0.9 miles Y Y No charge No charge N 1 1 6:00 a.m.- N N $35.00 Washington, DC 10:00 p.m.1515 Rhode Island Avenue NW

19 Hotel Helix $249/$249 $269/$289 Y 1 mile Y N No charge No charge N 1 1 7:00 a.m.- N N $38.00 1430 Rhode Island Avenue NW 10:00 a.m.

5:00 p.m.- 10:00 p.m.

20 Hotel Rouge $249/$249 $269/$289 Y 1.2 miles Y N No charge No charge N 1 1 7:00 a.m.- N N $33.00 1315 16th Street NW 10:00 a.m.

5:00 p.m.- 10:00 p.m.

21 The Mayflower Renaissance $315/$315 $335/$355 Y 1.1 miles Y Y No charge No charge N 1 1 6:00 a.m.- N N $45.00 1127 Connecticut Avenue NW 2:00 p.m.

5:00 p.m.- 1:00 a.m.

Headqu arters

Convention Center

Thomas Circle

White House East

Scott Circle

hotelsMap Number

Business Center

Smoke-Free Hotel

Coffee Maker

Bars

Comp. Breakfast

Single/Double

Rate

Triple/Quad

Rate

Distance from

Convention

Center

High-Speed

Internet

Onsite

Fitness Center

Indoor/Outdoor

Pool

Room Service

Self Parking

Valet Parking

Restaurants

*Continental**AmericanPlease Note: This information was accurate as of June 2012. Fees and amenities listed are subject to change without notice.

38 AACR Annual Meeting 2013 Abstract Submission Deadline: November 15, 2012


22 Hotel Palomar Washington, DC $279/$279 $299/$319 Y 1.4 miles Y Y No charge No charge Indoor 1 1 24 hrs. N $41.00 $41.00 2121 P Street NW

23 The Dupont Hotel $255/$255 $275/$285 Y 1.3 miles Y N No charge No charge N 1 1 7:00 a.m.- N N $32.00 1500 New Hampshire 10:00 p.m.Avenue NW

24 The Fairfax at Embassy Row $279/$279 N/A / N/A Y 1.5 miles Y Y No charge No charge N 1 N 24 hrs. N N $40.00 2100 Massachusetts Avenue NW

25 Topaz Hotel $249/$249 $269/$289 Y 0.9 miles Y Y No charge N N 1 1 7:00 a.m.- N $41.00 $41.00 1733 N Street NW 10:00 a.m.

5:00 p.m.- 10:00 p.m.

26 Hotel George $255/$255 N/A / N/A Y 1.1 miles Y Y No charge No charge N 1 1 6:00 a.m.- N N $43.0015 E Street NW 10:00 p.m.

27 Hyatt Regency Washington $275/$275 $300/$325 Y 1.2 miles Y Y No charge No charge Indoor 1 1 24 hrs. N N $45.00on Capitol Hill400 New Jersey Avenue NW

28 Liaison Capitol Hill $259/$259 $289/$319 Y 1.2 miles Y Y No charge No charge Outdoor 1 1 6:00 a.m.- N N $48.00415 Jew Jersey Avenue NW 12:00 a.m.

29 Phoenix Park Hotel $239/$239 $269/ N/A Y 1.4 miles Y Y No charge No charge N 1 1 7:00 a.m.- N N $37.00520 North Capitol Street NW 11:00 p.m.

30 Washington Court Hotel $265/$265 $285/$305 Y 1.2 miles Y Y No charge No charge N 1 1 6:00 a.m.- N N $43.00525 New Jersey Avenue NW 10:00 p.m.

31 One Washington Circle Hotel $239/$239 $259/$279 Y 1.6 miles Y Y No charge No charge N 1 1 6:00 a.m.- N N $35.00One Washington Circle NW 10:00 a.m.

11:00 a.m.- 2:00 p.m.5:00 p.m.- 10:00 p.m.

32 Melrose Hotel $245/$245 $265/$285 Y 1.7 miles Y Y No charge No charge N 1 1 24 hrs. N N $40.00Washington, DC2430 Pennsylvania Avenue NW

33 Holiday Inn Capitol Hotel $209/$209 $229/$229 N 1.6 miles Y Y No charge No charge Outdoor 1 1 7:00 a.m.- N $34.00 N550 C Street SW 10:00 p.m.

34 L'Enfant Plaza Hotel $249/$249 $269/$289 Y 1.8 miles Y Y No charge No charge Outdoor 1 1 6:00 a.m.- N $40.00 $42.00480 L'Enfant Plaza SW 11:00 p.m.

35 Mandarin Oriental, $315/$315 N/A / N/A Y 1.7 miles Y N No charge No charge Indoor 2 1 24 hrs. N N $45.00Washington DC1330 Maryland Avenue SW

36 Embassy Suites $259/$259 $269/$279 N 1.8 miles Y Y No charge No charge Indoor 1 1 12:00 p.m.- A** $35.68 NWashington, DC Downtown 10:00 p.m.1250 22nd Street NW

37 Fairmont Washington, DC $267/$267 $297/$327 N 1.9 miles Y Y $14.95 $15.00 Indoor 1 1 24 hrs. N N $45.002401 M Street NW

38 Park Hyatt Washington $267/$267 N/A / N/A N 2.0 miles Y N Wired No charge Indoor 1 1 24 hrs. N N $41.501201 24th Street NW No charge

39 St. Gregory Luxury $242/$242 N/A / N/A Y 1.4 miles Y Y No charge No charge N 1 1 7:00 a.m.- N N $33.00Hotel & Suites 10:00 a.m.2033 M Street NW 11:00 a.m.-

4:00 p.m.5:00 p.m.- 11:00 p.m.

40 The Westin Georgetown, $265/$265 $285/ N/A Y 1.9 miles Y Y No charge No charge Outdoor 1 1 24 hrs. N $34.00 $40.00Washington DC2350 M Street NW

41 Washington Marriott $269/$269 $289/$309 Y 1.8 miles Y Y No charge No charge Indoor 1 1 6:30 a.m.- N $36.00 $40.001221 22nd Street NW 11:00 p.m.

42 Renaissance Washington, DC $279/$279 $299/$319 Y 1.7 miles Y Y No charge No charge N 1 1 7:00 a.m.- N N $35.00Dupont Circle Hotel 12:00 a.m.1143 New Hampshire Avenue NW

Dupont Circle

Capitol Hill

Washington Circle

South West/Waterfront area

West End

hotelsMap Number

Business Center

Smoke-Free Hotel

Coffee Maker

Bars

Comp. Breakfast

Single/Double

Rate

Triple/Quad

Rate

Distance from

Convention

Center

High-Speed

Internet

Onsite

Fitness Center

Indoor/Outdoor

Pool

Room Service

Self Parking

Valet Parking

Restaurants

39



hOTEl MAP


AACR Scientific Achievement AwardsSince 1961, the AACR has presented more than 295 prizes,awards, and lectureships to recognize the scientific achievementsof scientists and physicians whocollectively have made significantcontributions to the understanding,diagnosis, prevention, and treatmentof cancer. The AACR encourages you to nominate a deservingcolleague for one of 13 ScientificAchievement Awards to be presented at the Annual Meeting2013. Details about the eligibilitycriteria and nomination process forthese honors can be found at:www.aacr.org/ScientificAwards.

Continuing Medical Education (CME) Credits

Continuing Medical Education Credits will be available. Details will be available atwww.aacr.org/AACR2013, in theAnnual Meeting 2013 Program, and at the CME Desk on site at the meeting.

Exhibit ShowThe 2013 AACR Exhibit Show willgather a wide array of companiesfrom around the world with the latestin products and services in laboratoryand clinical research. The exhibits,located adjacent to the postersessions, make a significantcontribution to the educational valueof the meeting. Special areas ofinterest, including the not-for-profitsection and Publishers Row, will befeatured on the show floor. Visit theExhibitor Spotlight Theater whereexhibitors have the opportunity toprovide a 60-minute presentation onnew products or services in anintimate setting to a targetedaudience. A complete schedule ofpresentations will be available on theAnnual Meeting website and in theExhibitor Directory.

Exhibitor-Hosted Refreshment Breaksprovide attendees with anopportunity to connect with other

attendees and exhibiting companies.Complimentary coffee, tea, softdrinks, and a variety of snacks will beoffered at specified times on eachday that exhibits are open.

Please add time to your overallschedule to visit the Show Floor,where over 450 exhibiting companieswill be on hand to showcase theirproducts and services. Be sure tovisit the AACR website for anupdated list of exhibitors.

If your company would like to exhibitand receive the many benefits ofexhibiting, please contact LisaMcGlashen, Exhibits Manager, at(215) 440-9300 or by e-mail [email protected].

Support OpportunitiesThe AACR welcomes support fromcorporations, foundations, and otherorganizations that share its mission toprevent and cure cancer and that areinterested in helping to defray thecosts of presenting this importantinternational meeting on cancerresearch. Numerous benefits areprovided in recognition of theirgenerous financial assistance. A widearray of support opportunities isavailable for many of the componentsof the scientific program (i.e., PlenarySessions, Symposia, Forums, CurrentConcepts Sessions, MethodsWorkshops, Educational Sessions,Meet-the-Expert Sessions,constituency programs, etc.), as wellas the Program, Proceedings, andother Annual Meeting publications,the Internet Café, social events suchas coffee breaks, the AnnualPresident’s Reception, and more. Fora complete list of supportopportunities as well as an outline oftheir many benefits, please contactBert Thomas, Director, CorporateAlliances, at (215) 446-7159 or viae-mail at [email protected].

Space for Special FunctionsThe AACR will consider requests forspace for special functions orreceptions in the hotels listed on

pages 38-39 of this publication.These requests will be handled on afirst-come, first-served basis. Anycorporation that wishes to entertainduring the Annual Meeting must bean exhibitor at the meeting. Spacerequest forms are available on theAACR website and are included in theExhibitor Services Manual.

Note: Outside educationalprograms, including company-sponsored symposia, will not bepermitted at any time during theAACR Annual Meeting 2013.

Assistance for PhysicallyChallenged RegistrantsThe AACR Annual Meeting isaccessible to all attendees. Registrantswith special requirements fortransportation, hotel accommodations,or other facilities connected with themeeting should notify the AACR inadvance by checking the appropriatebox when registering and providing thenecessary details or by e-mailing theMeetings and Exhibits DepartmentStaff at [email protected]. In addition,a list of organizations in Washingtonthat offer special equipment or servicesfor the physically challenged will beposted at www.aacr.org/AACR2013 inJanuary 2013.

Child CareThe AACR will provide professionalchild care services at reduced ratessubsidized by the Association forinfants and children ages 6 months to12 years during the Annual Meeting.The exact hours, location, and costsof this service will be available inJanuary 2013 on the AACR website.

Nursing Mothers SuiteAnnual Meeting participants who arealso nursing mothers will find theNursing Mothers Suite to be aprivate, comfortable, and secureenvironment in which to nourish andnurture their babies. AACR-Women inCancer Research is pleased tosponsor this important service.Additional information will be postedat www.aacr.org/AACR2013.

gENERAl iNfoRMATioN

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CALL FOR ABSTRACTS Abstract Submission Deadline: November 15, 2012 www.AACR.org

A N N U A LMEETING

2013

April 6-10, 2013Walter E. Washington Convention Center

Washington, DC

615 Chestnut Street, 17th FloorPhiladelphia, PA, 19106-4404

(215)440-9300 • Fax: (215)440-9185Email: [email protected]

See inside for the latest Annual Meeting information:• Instructions for abstract submission• Detailed program in progress• Financial support for attendees• Meeting registration instructions• Housing reservations• Early registration rates

13AM_CFA_covers_Layout 1 8/29/12 11:10 AM Page 1

Documents

AACR Annual Meeting 2013