ABSTRACTS. The greatest number of cysts found in sections of the above· mentioned muscles of a horse was forty-five, and the greatest number observed in a section was seven. Fatty degeneration was observed in the muscles of horses dying from horse-sickness, pernicious an::emia, piroplasmosis, and tox::emia, the degeneration in these cases being attributed to the effect of the toxins produced in these diseases. In some instances the intermuscular tissue was <:edematous (horse-sickness cases). No changes were noted in the peripheral nerves, with the exception of three horses affected with dourine, in which a neuritis was found to exist. Horses affected with dourine showed little or no sarcosporidial infection. Symptoms characteristic of lamziekte in cattle were not observed in the sheep and horses from which the muscular and nerve tissues were collected and examined. (J. Walker, Seventh and Eighth Reports of the Director 0/ Veterinary Research, Union cif South Afrti:a, 1920, pp. 397.424.) AN AUTOGENOUS VACCINE FOR STRANGLES. THE autogenous vaccine recommended in this article has at least two virtues, namely, that it is quickly prepared and that no very complicated technique is entailed. The method is as follows :- Strangles pus from the selected patient is collected in a clean receptacle, well shaken, and stirred with twice its volume of ether to break up all coarse particles. When the mixture has become homogenous six times its volume of the following solution is added:- Iodine . I gm. Potassium Iodide 4 gms. Distilled Water 1000 cc. This solution is preferably to be added in three or four portions at intervals, the whole process of adding and mixing occupying about an hour. Tlte whole is now filtered through several layers of sterile gauze and collected in a sterile flask. The filtrate constitutes the finished vaccine and may be used after an hour's interval. There is no reason why a similar polyvalent autogenous vaccine should not be prepared from material collected from several animals. It is suggested that serial injections of increasing doses be adopted, extending over a period of six days at least, and intramuscular injection into the middle of the side of the neck is advised. The doses employed by the author were: first day I cc., second day 1"5 cc., third day 2 cc., fourth, fifth, and sixth days 2·5 cc. This method produces no untoward symptoms, either local or systemic, although a slight elevation of temperature is not uncommon. The author quotes four cases in which the course of the disease was favourably influenced, and is convinced that although the method effects no magical cures it is at least valuable in that it reduces the tendency to chronic sequel::e. It has at least the virtue of being perfectly harmless. (Monbet, Rev. Vet., T. LXXIII., 19 21 , pp. 338-345.

An Autogenous Vaccine for Strangles

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Page 1: An Autogenous Vaccine for Strangles

ABSTRACTS.

The greatest number of cysts found in sections of the above· mentioned muscles of a horse was forty-five, and the greatest number observed in a section was seven.

Fatty degeneration was observed in the muscles of horses dying from horse-sickness, pernicious an::emia, piroplasmosis, and tox::emia, the degeneration in these cases being attributed to the effect of the toxins produced in these diseases. In some instances the intermuscular tissue was <:edematous (horse-sickness cases).

No changes were noted in the peripheral nerves, with the exception of three horses affected with dourine, in which a neuritis was found to exist.

Horses affected with dourine showed little or no sarcosporidial infection. Symptoms characteristic of lamziekte in cattle were not observed in the

sheep and horses from which the muscular and nerve tissues were collected and examined. (J. Walker, Seventh and Eighth Reports of the Director 0/ Veterinary Research, Union cif South Afrti:a, 1920, pp. 397.424.)

AN AUTOGENOUS VACCINE FOR STRANGLES.

THE autogenous vaccine recommended in this article has at least two virtues, namely, that it is quickly prepared and that no very complicated technique is entailed. The method is as follows :-

Strangles pus from the selected patient is collected in a clean receptacle, well shaken, and stirred with twice its volume of ether to break up all coarse particles. When the mixture has become homogenous six times its volume of the following solution is added:-

Iodine . I gm. Potassium Iodide 4 gms. Distilled Water 1000 cc.

This solution is preferably to be added in three or four portions at intervals, the whole process of adding and mixing occupying about an hour. Tlte whole is now filtered through several layers of sterile gauze and collected in a sterile flask. The filtrate constitutes the finished vaccine and may be used after an hour's interval. There is no reason why a similar polyvalent autogenous vaccine should not be prepared from material collected from several animals.

It is suggested that serial injections of increasing doses be adopted, extending over a period of six days at least, and intramuscular injection into the middle of the side of the neck is advised. The doses employed by the author were: first day I cc., second day 1"5 cc., third day 2 cc., fourth, fifth, and sixth days 2·5 cc. This method produces no untoward symptoms, either local or systemic, although a slight elevation of temperature is not uncommon.

The author quotes four cases in which the course of the disease was favourably influenced, and is convinced that although the method effects no magical cures it is at least valuable in that it reduces the tendency to chronic sequel::e. It has at least the virtue of being perfectly harmless. (Monbet, Rev. Vet., T. LXXIII., 1921 , pp. 338-345.