Slide 2 AP Biology 2006-2007 Cellular Respiration Harvesting Chemical Energy ATP Slide 3 AP Biology 2006-2007 The Point is to Make ATP! ATP Whats the point? Whoa! HOT stuff! Slide 4 AP Biology Harvesting stored energy Energy is stored in organic molecules ____________________________________ ____________ eat these organic molecules food digest organic molecules to get ____________________________________ controlled release of energy burning fuels in a series of step-by-step enzyme-controlled reactions Slide 5 AP Biology Harvesting energy stored in glucose Glucose is the model ____________________________________ C 6 H 12 O 6 6O 2 6CO 2 6H 2 OATP + ++ CO 2 + H 2 O + heat fuel (carbohydrates) COMBUSTION = making a lot of heat energy by burning fuels in one step RESPIRATION = making ATP (& less heat) by burning fuels in many small steps CO 2 + H 2 O + ATP (+ heat) ATP glucose glucose + oxygen carbon + water + energy dioxide respiration O2O2 O2O2 enzymes + heat Slide 6 AP Biology How do we harvest energy from fuels? Digest large molecules into smaller ones break bonds & move electrons from one molecule to another as electrons move they carry energy with them that energy is stored in another bond, released as heat, or harvested to make ATP e-e- ++ e-e- + loses e-gains e-oxidizedreduced REDOX e-e- Slide 7 AP Biology How do we move electrons in biology? Moving electrons in living systems electrons cannot move alone in cells electrons move as part of H atom _____________________________________ p e + H + H + loses e-gains e-oxidizedreduced oxidationreduction C 6 H 12 O 6 6O 2 6CO 2 6H 2 OATP +++ oxidation reduction H Slide 8 AP Biology Coupling oxidation & reduction REDOX reactions in respiration release energy as break down organic molecules break C-C bonds strip off electrons from C-H bonds by removing H atoms C 6 H 12 O 6 CO 2 = __________________________ electrons attracted to more electronegative atoms in biology, the most electronegative atom? O 2 H 2 O = _______________________________ __________________________________________ __________________________________________ __ C 6 H 12 O 6 6O 2 6CO 2 6H 2 OATP +++ oxidation reduction O2O2 Slide 9 AP Biology Oxidation & reduction Oxidation ______________ Reduction ______________ C 6 H 12 O 6 6O 2 6CO 2 6H 2 OATP +++ oxidation reduction Slide 10 AP Biology Moving electrons in respiration __________________ move electrons by shuttling H atoms around NAD + NADH (reduced) FAD +2 FADH 2 (reduced) + H reduction oxidation P OO OO O OO P OO OO O OO C C O NH 2 N+N+ H adenine ribose sugar phosphates NAD + nicotinamide Vitamin B3 niacin P OO OO O OO P OO OO O OO C C O NH 2 N+N+ H H NADH carries electrons as a reduced molecule reducing power! like $$ in the bank Slide 11 AP Biology Overview of cellular respiration 4 metabolic stages _______________________ 1. ______________________ respiration without O 2 in cytosol _______________________ respiration using O 2 in mitochondria 2. ______________________ 3. ______________________ 4. ______________________ C 6 H 12 O 6 6O 2 6CO 2 6H 2 OATP +++ (+ heat ) Slide 12 AP Biology 2006-2007 The Point is to Make ATP! ATP Whats the point? Slide 13 AP Biology ___________________ __________________ conformational changes bond P i to ADP to make ATP __________________ allow the H + to flow down concentration gradient through ATP synthase ADP + P i ATP H+H+ ADP + P i H+H+ H+H+ H+H+ H+H+ H+H+ H+H+ H+H+ H+H+ And how do we do that? ATP Slide 14 AP Biology 2006-2007 H+H+ ADP + P i H+H+ H+H+ H+H+ H+H+ H+H+ H+H+ H+H+ H+H+ ATP Got the Energy? Ask Questions!