HIDDEN DANGERS OFYOUR MORNING SHOWER

You wouldn't knowingly bathe in toxins every morning - - or set out to ravage your lungs and sinuses, irritate your allergies, aggravate your skin, or...perhaps most horrifying of all...willingly increase your risk of cancer...would you? Of course not. But the fact is, the chlorine in your shower water is a powerful toxin - - deadly to bacteria and fungi, and poison for your body. You absorb 6 to 100 times more chlorine in a shower than you do by drinking the same water!!! 2/3 of chlorine consumption comes from the shower. When you take a 5 minute shower its equal to drinking chlorinated water for 30 days. That is how quickly the body absorbs chlorine into the body. When we're under that hot water, our pores open up and soak up the chlorine. With the shower system, you not only don't have to worry about the chlorine, but it also runs the water through a magnet so you get energized water that goes directly into the body. A warm shower opens up your pores, causing your skin to act like a sponge. As a result, you not only inhale the clarion vapors, you also absorb them through your skin, directly into your bloodstream - - at a rate that's more than 6 times higher than drinking. In terms of cumulative damage to your health, showering in chlorinated water is one of the most dangerous risks you take every day. Inthe short-term, chlorinated shower water irritates your eyes, your sinuses, your throat, your skin, and your lungs. Long-term risks include excessive free radical formation (which makes you age faster), higher vulnerability to genetic mutation and cancer development, difficulty metabolizing cholesterol and hardened arteries. Showering in chlorine-treated water is a serious risk - - but it is also one of the very few risks you can immediately erase. And it is up to you to protect yourself.

For almost 100 years, chlorine has been added to disinfect our municipal water supply. The level of chlorine in your area depends on thequality of your water supply, but even if there's no noticeable taste or smell, the chlorine is present, as are the byproducts of chlorination,which include some of the most potent carcinogens known.Research conducted jointly at Harvard University and the Medical College of Wisconsin found that chlorinated water was the direct cause of 9% of all bladder cancers and 15% of all rectal cancers in the U.S.There is also evidence that chlorine destroys protein in your body. As I am sure you are already aware, this disinfectant bleach dries your skin, causes damaged and brittle hair and burns your eyes. But what you may not be aware of is that if you suffer from any of the following chlorinated water makes your condition worse: Asthma—sinus conditions--Allergies--Skin rashes--Emphysema and that's just for starters. The evidence is clear. The risks are tremendous. The advice is simple:

Stop chlorinating your body. You no longer have to gamble with your health on contaminated shower water. Not only can you effectively remove the chlorinebyproducts from your shower water - - you can also significantly reduce lead, hydrogen sulfide (rotten egg smell), iron oxides and sediments. Simply replace your existing showerhead with the Nikken Shower System. Nikken now adds Magnetic Water Technology to its Advanced Chlorine Filtration to create the ultimate shower system. This is the only product on the market to combine these two water technologies. The Nikken Shower System offers you maximum protection from both crystallization and chlorine. Nikken's Magnetic Water Technology improves water simply and naturally, to help reduce the crystallization, which occurs through normal water usage. This prevents scaling inside pipes and fixtures and can lessen the deposit left on hair and skin.Nikken's Advanced Chlorine Filtration uses the only non-carbon shower filtration to remove both free-radical chlorine and most types of combined chlorine. And with a choice of two settings on the deluxe showerhead, you can alternate between a regular spray and pulsating jets for an invigorating shower massage.Nikken’s PiMag Water Filtration System creates water virtually free of organic matter – chlorine, heavy metal contaminations, etc.Nikken’s Shower system has a filter that takes out the chlorine and other sediments. It also helps remove lead, "rotten egg smell", iron oxides and sediments.1Water You DrinkCan Make or Break Your HealthIf someone were to ask, “Is water important to your health?” we would most likely answer, “Of course” and add, “I know we’re supposed to drink about 8 glasses a day.” Some people may even follow these recommendations, but far more are satisfied with just parroting back this basic knowledge. We typically minimize the real importance of water. Maybe water is not flashy enough yet water deserves top billing where health is concerned. The practitioners and organizations, which emphasize the importance of water, deserve our applause. If our consciousness and consumption of water can be raised we will have taken a gigantic step in preventative care.According to Rudolph Ballantine, M.D., author of Radical Healing (1999), “It is a significant advancement in biological science that we are beginning to see water as not merely an inert medicine in which compounds float but as something alive with complex molecules, changing and charged with information. The more we learn about water, the more obvious it will become that a good quantity and quality of water is a cornerstone of sound health.”

Exactly How Important is Water Really?CONSIDER THIS:- We are composed of 70% water (some sources say up to 80%) Think about that…. we are mostly water- Brain cells are 75-85% water. The right kind of water improves the mind and brain. Doesn’t it stand to reason that there has to be something hugely special about this substance as it relates to our system? Our adaptive mechanism keeps the brain hydrated first, sacrificing other areas if necessary. The brain uses electrical energy that is generated by hydrolysis as the preferred source over the energy provided by blood sugar (glucose).- The water volume that is stored in the disc cores (especially the 5th lumbar disc) supports -75% of the weight of our upper body- 50% of cartilage in joints and discs is made of water- Blood is composed of about 50% water. Every 90 days we build a brand new bloodstream.- OUR TOTAL BODY WATER IS REPLACED ABOUT EVERY 15 DAYS. THINK ABOUT THAT. IN ABOUT 2 WEEKS YOU COULD REPLACE 70% OF YOURSELF WITH SOMETHING HEALTHY AND PURE.- Water is more important than food! The complete role of water in our system is only partially understood. So far we know: Water supplies the body’s tissues with oxygen and nutrients. Water is a solvent not just a transport mechanism. It holds nutritive factors in solution while it delivers necessary components throughout the body.a. Water carries away excess wastes and flushes out toxins.b. Water is a natural diuretic.c. Water metabolizes stored fat and reduces fatty deposits.d. Water controls our body temperature.e. Water is Mother Nature’s greatest beauty tonic.f. Water protects our body’s cells from attacks from diseases, viruses, etc. If cells become water starved they become shriveled up, parched and dry, making it easier for foreign invaders to enter the cells.g. Water is necessary for the chemical reactions in our body to occur through a process of hydrolysis.h. Water flows through our cell membranes generating hydroelectric energy (voltage) that is converted and stored in ourcells as energy (ATP and GTP).i. Water holds our cell contents in their proper structural place, allowing for optimal functioning.What we are just beginning to learn about water (again, 70-80% of who we are) is very exciting! It concerns the energetic properties of water. ‘Dead water’ has lost the subtle energetic quality that nourishes us on a non-physical level.

Since the function of the physical components has been the exclusive focus of biochemists, nutritionists, etc. how we might be taking up the energy of water has been largely overlooked. In Western society we are only beginning to develop technology that allows us to tap into this level of what’s going on. Perhaps the study of the energetics of food, water, etc. will be the science of the new millennium. Pi-water is at the forefront of this endeavor.Water Deficiency SyndromesBy understanding the proportion of water occupying our cells, tissues and organs and the known functions of water, we can already begin to appreciate what might happen if our bodies lack water. But beyond using our imaginations, here are some specifics concerning water deficiency.- 75% of Americans are chronically dehydrated.- In 37% of Americans, the thirst mechanism is so weak that it is often mistaken for hunger.- Even MILD dehydration will slow down one's metabolism as much as 3%.- One glass of water shut down midnight hunger pangs for almost 100% of the dieters studied in a U-Washington study.- Lack of water, the #1 trigger of daytime fatigue.2- Preliminary research indicates that 8-10 glasses of water a day could significantly ease back and joint pain for up to 80% of sufferers.- A mere 2% drop in body water can trigger fuzzy short-term memory, trouble with basic math, and difficulty focusing on the computer screen or on a printed page. Drinking 5 glasses of water daily decreases the risk of colon cancer by 45%, plus it can slash the risk of breast cancer by 79%, and one is 50% less likely to develop bladder cancer. Dehydration is the number one stressor of the human body – or of any living matter. We can be deficient in water just like a vitamin deficiency with specific symptoms resulting from this. And just as the simple treatment for vitamin and mineral deficiencies is to get them into our system, the way to treat water deficiency is by drinking water.Chronic dehydration is a disease producer. When our body is dehydrated the bi-layer membranes that surround cells contract in thickness. It forms a barrier that prevents further dehydration – but which also obstructs the free movement of molecules so that metabolism, exchange of chemicals and elimination of toxins are limited. While usually we consider thirst, dry mouth and skin as signs of dehydration we are now beginning to realize a whole other spectrum of symptoms which signal dehydration, i.e.;- Sinus problems, allergies and breathing difficulties- Joint discomforts, neck pain, etc.- Obesity and digestive problems- Headaches

- Heart problems, high blood pressure, high cholesterol- Stress- Sleep disorders- Impotence- Depression and brain dysfunctionIf we go through the exercise of tracing how water deficiency contributes to these symptoms we will increase our consciousness regarding the absolute need to drink sufficient amounts of healthy water. (We have people like Dr. Batmanhelijid, author of Your Body’s Many Cries for Water to thank for these types of analyses and for stressing the simple medicine of things like proper sleep, proper hydration, etc.)Pain as a symptom of water deficiencyHistamine production increases when dehydration is present. Histamines are active in water management and delivery. Prostaglandin’s, kinins, and PAF are also water intake and distribution managers. The higher the production of these items (in part as a protective response to dehydration) the higher the chances for pain. These chemicals often cause irritation when making contact with the painsensing nerves in the body. Histamine also causes bronchial constriction as the body attempts to conserve the evaporation of water from the lungs. Dyspeptic pain, rheumatoid arthritic pain, anginal pain, migraines, colitis and allergic and asthmatic reactions are all, in part, connected to overproduction of histamines, prostaglandin’s, etc.Asthma and Allergies as symptoms of water deficiencyIn addition to the histamine release, if the body is dehydrated, a protective response is to produce more mucous in the lungs to protect the tissues from drying out further and from loosing more body water through evaporation from the lungs.Neurological symptoms of water deficiencyChronic dehydration causes brain cells to shrink. At 85% water, these cells depend upon water to deliver and help with the formation of neurotransmitters. If this is not occurring, degenerative changes can occur. The more stressed a system becomes due to dehydration the more stress hormones it releases such as endorphins, cortisone release factor, vasopressin, prolactin, renin-angiotensin, etc. While we won’t go into all the effects of these chemicals, we should know that their release creates further stress if not flushed out of the system.Without water, it is easy to get into a cycle of stress, which eventually manifests as things like chronic fatigue, depression, etc. Additionally we see increased problems with information processing, memory loss, confusion, etc. Without adequate water the brain is also depleted of the energy created through hydrolysis. And finally, (from our limited knowledge base thus far) we also know that dehydration causes depletion of tryptophan, which is a necessary

component to the formation of major neurotransmitters like serotonin, tryptamine, melatonin, etc. Tryptophan is also central to sound sleeping patterns.Cardiac symptoms, High Cholesterol & High Blood Pressure - symptoms of water deficiencyAgain, as an adaptive process to conserving water, when the fluid volume in vessels decreases, the vessels tighten up to keep blood moving. Eventually capillary beds shut down. Cholesterol is one agent, which regulates permeability of the cell membrane to water. Increased cholesterol is produced as the body seeks to keep cells lubricated. Also, if we have inadequate water intake prior to eating - as the food enters our intestines it must pull fluid from within the system in order to digest the food. As a result, our overall blood supply becomes more concentrated and less viscous. The first place oxygenatedblood travels, is to the heart and lungs. These areas are the most vulnerable and would be the first to come in contact with deposits left from the ‘concentrated’ blood.3Colitis as a symptom of water deficiencyA hormone/neurotransmitter “motilin” is produced as we drink water. The effect of motilin on the intestinal tract is to produce rhythmic contractions of the intestines. Without this peristalsis we increase the risk of colitis and hiatal hernia.Arthritis as a symptom of water deficiencyWater functions as a lubricant allowing two opposing forces to freely glide over one another during joint movement. In dehydrated cartilage the rate of abrasive damage is increased. Swelling of joints may also occur as the dehydrated system attempts to compensate by expanding vessels around the joint in order to get water into the bone marrow for red blood cell production.By now, you must be wondering, “Am I dehydrated?” Actually most people are. It has been estimated that 80% of our elderly population is water deficient. Our younger people especially need early education and role modeling of water consumption so that lifetime health habits can be established. We would be doing a wonderful service to our future generations and to greatly curbing the exorbitant amount of funds poured into “illness” care.Is There Any One Water That’s Better Than Others?YES! Surface tension seems to be of primary importance in water quality. Scientists are looking towards water treatments that lower the surface tension of the water molecule. Fluids with lower surface tension move freely through the intestinal lining, the capillaries and move freely through extra and intra-cellular spaces, entering the cells and washing away molecular debris. Hard water has a high surface tension while soft water has a low surface tension.

Minimally, we need water that is clean and contains the necessary minerals. If you look at pictures of water droplets in various kinds of water - the differences between pure and polluted water are quite striking. We need the best quality water to maintain the best health. Pure water is a health tonic. Actually, the secret of health lies in internal cleanliness. It means being 100% free of unnecessary deposits.Before we look at what perfect water might be let’s look at what it’s not.Our Current Public Water System- 30% of Americans drink water that violates federal health standards.- A recent ABC news expose revealed over 700 chemicals found in drinking water. 129 of these chemicals posed health threats according to the EPA. Our water may contain radioactive particles, heavy metals, radon, gas solvents, disinfectant by-products and solid particulate such as asbestos. Inorganic minerals, toxins and chemicals can pollute, clog up and turn tissue into ‘stony’formations throughout the body - generating pain, illness and premature aging.- The EPA has also said that the tap water of 30 million Americans contains dangerous levels of lead. More than 90% of water companies don’t use the available technology to remove chemicals and toxins from drinking water. In fact chlorine, fluoride, calcium carbonate, magnesium carbonate and potassium carbonate are often put in the water to ‘purify’ it. These substances are very unhealthy for us.Fluoride- Serious health problems may be caused or worsened with fluorinated water. Cancer, digestive problems, urinary disorders, circulatory diseases, mental and neural impairments, blood dyscrasias, immune system suppression, eye diseases, endocrine disorders, skin, nail and hair problems, bone and joint conditions, teeth and gum disease and birth defects have all been negatively impacted by fluoride use.- 11 associations have stopped endorsing water fluoridation in 1996, including the AMA, the Amer. Cancer Assoc., the Amer. Diabetes Assoc., and the Amer. Psychological Assoc.- The Journal of the AMA in a study of 3,578 seniors living in fluorinated areas found a 41% increase in hip fractures.- The National Library of Medicine has revealed that bone density decreased 45% with fluoride. It is suspected that fluorides leach calcium from skeletal structures. www.johnleemd.net/breaking_news/fluoridation_02.html- The National Academy of Sciences has found that fluorine slows down DNA repair activity.

Chlorine- Since 1900, beginning with large-scale chlorination, the occurrence of heart disease has increased almost 400%. Dr. Price, author if “Coronaries/Cholesterol/Chlorine”, firmly believes free chlorine to be a major contributor to heart disease causing fats in the blood to form deposits.- Highly chlorinated water has resulted in a shift from beneficial HDL to harmful LDL.- 75% of our water is chlorinated. 66 new carcinogenic compounds have been isolated from chlorinated water. Known carcinogens such as chloroform and other trihalomethanes are formed when chlorine reacts with organic compounds in the water. These chlorines accumulate in fatty tissue, such as breast tissue. New evidence suggests that chlorinated water increases the risk of cancer for the roughly 200 million Americans who drink it.Calcium carbonate (lime)- This ingredient is not only used in water purification but in making concrete. Think of our blood vessels. The hardening is most detrimental in the small arteries and vessels of the brain. Not all forms of calcium are beneficial.4Lead- It has been estimated that lead may be contaminating more than 40 million Americans.- A recent study of 5,000 women in the state of California revealed that women who drank tap water had twice as many miscarriages and children with birth defects as those who drank bottled or filtered water. Five other studies reached the same conclusion.TYPES OF WATER WHICH CARRY MAXIMUM BENEFITEffects of Magnetizing WaterResearch has shown the following can be observed after water has been magnetized:1. A decrease in water weight. (An article in the Washington Post reported on a man in Tlacote, Mexico who ‘discovered’ water on his property that was lighter than tap water. This water was effective in the treatment of AIDS, cancer, obesity and high cholesterol. It was dubbed ‘miracle water’.2. No changes in mineral concentrations.3. A decrease in the quantity of nitrogen dissolved. (In fish tanks nitrogen accumulates in stagnant water and uses up oxygen needed by fish. Magnets can be used to fight the microorganism invasion or algae overabundance.4. An increase in the number of crystallization centers. Magnetic fields break up clusters, which lowers the surface tension of water molecules allowing for easier absorption. This is a key feature. In recent years people have been

focusing on ways to produce water with lowered surface tension. Essentially, the water is not as ‘sticky’. Calcium carbonate is electrically neutralized and remains in suspension. The magnetized water dissolves deposits while flowing through pipes, this pertains to industrial pipes as well as to our own ‘internal piping’, gallbladders, urinary tracts and calcium and cholesterol clogged areas.5. Altered binding forces between water molecules and various proteins, salts and minerals appear to endow the water with the ability to dissolve buildups of various types of salts and minerals. This increased mineral solubility also improves the distribution of nutrients throughout the system.6. An increased ability to establish a balanced ph. All enzyme activity and fermentation processes are only possible within a certain pH environment, which magnetic fields help to create. They specifically help with resolving acidic conditions oftentimes seen with chronic diseases.7. An increased enzyme reaction time. Every function of the body is dependent upon enzyme activity. Enzyme activity occurs more efficiently in solutions of lower viscosity.8. An increase in hydrogen ion activity. This softens water without using salt.In accordance with the properties described of magnetized water many experiments and therapeutic results have been reported. For example:- Reduced cholesterol due to decreased build up and hardening of arteries (in as short as three weeks).- Improved digestive functions, decreased gastric acid- Tissue regeneration (a study in Puerto Rico of bed sores washed with magnetized water were healed within 4 to 14 days with no further recurrence).- Improved waste and toxin elimination- Strengthened immune system- Decreased fever- Increased vitality- Re-established metabolic balance- Decreased constipation and cleaner intestinal tract- Kidney and bladder stone reduction & decreased bladder rigidity. Ingestion of 50 ml magnetized water every 10 minutes for 8 to10 times has been effective for the treatment of urinary retention.- Reduced severity of menstrual problems- Reduced dental calculus and gingival inflammation. (A peer reviewed double blind, placebo controlled study in 1998 at the Med. Univ. of S. Carolina showed 64% less calculus, and a 27% lower rate for gingival inflammation. Johnson, Journal of Clinical Periodontology, 25 (1998).- Effective in the treatment of intestinal parasitic disease in children- Increased vegetable growth. Texas A and M University found that squash plants grown with magnetized water produced heavier vegetables.

- Increased productivity of livestock. Experiments with 85 cows revealed extra liter of milk produced daily, easier conception, & increased muscle tone for those cows given magnetized water as part of their diet. Sheep produced more wool and chickens produced more eggs over a longer duration.As a side note, the healing waters of Lourdes and Sedona are said to possess a high magnetic field.5Far-infrared Effects on WaterPhotons stimulate the endocrine system, metabolic processes, enzyme reactions and brain activity. Photons are a component of light.Without photons (energy from the sun’s rays) there is a lowering of cellular energy, glandular insufficiency reduced ability to burn fats and toxins and a reduced ability to absorb oxygen. Far-infrared can be infused into water giving it this same ‘light’ energy and giving it additional vitality. This process occurs with use of a material, which emits waves of 4-14 microns similar to the sun’s far-infrared rays. Just like magnetic deficiency syndrome and water deficiency syndrome, one can also have malillumination syndrome resulting in partial absorption of nutrients, fatigue, depression, suppressed immune function, hair loss, skin damage and other maladies. The greatest amount of the sun’s energy output is in the far-infrared spectrum. This band is not visible to the human eye. They are the safest and most beneficial for the body. It is perhaps not coincidental that photons, at the 4-14 microns wavelength are the closest match to the human cell, which measures 4-14 microns width.All humans send and receive FIR (far-infrared) waves and ours are similar to the resonance of a water molecule. This makes sense since we are 70-80% water that we would be emitting largely the qualities of water. We also know that substances of similar resonance can transfer and absorb energy easily from one another. In some respects, we fortify one another energetically. Perhaps this is one reason that newborns who are held more exhibit healthier growth and development and also why married couples live longer; maybe we will find it isnot just the social benefits of companionship but the energetic benefits as well.FIR waves have been strongly correlated with:- Increased blood flow (due in part to the heat and removal of deposits and toxins)- Reduced muscle spasms- Removal of toxins- Improved lymph flow- Suppressed growth of some cancers- Reduced soreness- Improved enzyme activity- Improved osmosis across the cell wall membrane

- Reduced acidity especially where lactic acid is concerned- Lower acidity also improves the ability of Ca++ to enter the cell which improves intra and extra-cellular communication which has a positive effect on the entire system- Assistance with eradication of anaerobic organisms- Attraction of calcium ions to cell membranes.The vibration of the far-infrared light waves vibrates the water molecules, which allows gases and other toxic materials to be released. When toxins come into contact with the clusters of water they are encapsulated. If they are then vibrated they are released and available to be flushed from the system instead of remaining attached to the water molecule. Although, far infrared is not yet well known in the U.S. for it’s healing capabilities, in Japan there is an Infrared Society composed of MD’s & physical therapists to further the intense research and support of this particular technology.

PI-WATERWhat is it?It is energy water. It is something alive. Essentially, it is a vibrational remedy, imprinted with subtle energy patterns. Pi-water was discovered through the study of botanical physiology. It was originally thought that a hormone was responsible for causing plants to bud. Dr. Yamashita was conducting research, attempting to isolate this hormone, when he discovered that what was causing the flower to bud was not a hormone at all but a very minute amount of ferric ferrous salt. In 1964, Dr. Yamashita, an agricultural scholar furthered his research and found that this substance had other highly beneficial qualities.Inducing this ferric ferrous salt into a high-energy state and infusing it through a ceramic filter process creates -water. A particle is a quantum particle smaller than an electron, neutron and proton. The meson causes the protons and neutrons to exchange energy states with one another, which create energy and electrical charges of it’s own. The amount of ferric ferrous (bivalent and trivalent ferrite) is minute, a quantum particle – essentially such a trace amount that it is only the energetic signature of the substance, which remains. (2x 10-12 mol.) Homeopathy also utilizes the trace signature of the substance. It is theorized that these quantum particles are conductors and are responsible for carrying information and cellular “memories” (previously encoded information) such as natural bio-energetic and healing processes. At an International Symposium on Preventative Oncology held in France in 1998, the participants were very excited about the extraordinary benefits of -water. The following was reported:- It is the closest water to human body water

- It possesses high anti-oxidation properties because of it’s ability to eliminate free radicals6- It provides bio-energy, for example there was an experiment where goldfish were able to live for up to 216 days in a sealed container living off the energy in the water. Under normal circumstances a goldfish would die after about 3 to 5 days in a container sealed in regular water.- It increases the body’s amount of natural killer cells- It enhances anti-body activities- It improves the self-healing activity of body cells – waking up cellular “memories” of health- It carries more oxygen throughout the body, creating an oxygen rich environment which destroys anaerobic organisms (cancer is anaerobic)- It creates minute water clusters which improves the functions of cells and the detoxifying effects of water- It improves cellular adaptation to stress and stressful environments- It neutralizes the pH of water, bringing it to just above 7 which is very close to the pH of the body (few filtration systems manage water pH, as well as magnetic forces , far-infrared wave and infusion)- It enhances the transmission of information throughout the bodyGiven the qualities of Pi-water, one can begin to appreciate its many uses. At this point most of the literature on -water comes from Asian sources. There they have had over 30 years of experience.Agriculturally, Pi-water has been used for cultivating crops without chemicals and for producing larger vegetables. Experiments were done with spinach plants, which are difficult to re-cultivate. With Pi-water, 25 consecutive cultivations were achieved. Comparisons can be made between two identical seedlings/bulbs. The one watered with Pi-water as opposed to regular waterdemonstrates improved health, lowered disease and higher growth rates.Livestock and Animals, have responded with improved meat quality, a decreased level of anaerobic fermentation, an increase in egg production, an improved taste, and lethargic animals became more active, playful and interested in their surroundings.Industrial use has shown that oxidation or rusting was greatly reduced. Dr. Takafumi Tsurumi has collected a series of clinical anecdotes and studies with some astounding results:- Stomach cancer eradication, decrease of brain tumor, improvement in leukemia- Dermatitis improvement, improvement with alopecia- Improvement in diabetes- Improved liver function after hepatitis

- Lowered blood pressure and improvement in cardiac output- Rapid recovery from stroke- Relief of headaches, stiff joints, constipation- Improved overall health- Improved immunity (intake of Pi-water should be increased in the early stages of a cold, flu or virus- AIDS virus reportedly does not seem to multiply in this high-energy environment.Pi-water has been used to store tissue samples instead of placing them in a hormone solution. The structure of the tissues remained intact for over 30 years using this process. In addition to the various medical uses, Pi-water has been used in;Cooking- Soaking meats increases tenderness- Fewer spices were needed as the tastes of foods were intensified.- Cleaning fruits and vegetables with Pi-water removes toxins and prolongs their freshness (many Japanese restaurants use Piwater filtration systems- Un-ripened bananas can be soaked for 30 minutes to sweeten their taste.Gardening- Spraying plants with Pi-water improves their colors- watering with Pi-water increases root growth and foliage. .Pets- Pets exhibit a higher energy level when drinking Pi-water- It is also beneficial as an odor remover when simply sprayed by a spray bottle or if the pet consumes the water. Spraying areas with Pi-water will remove odor possibly making other unnecessary.- Spraying their coat with the water will enhance shinier and cleaner fur.Cleaning- Improved hair cleanliness, as well as skin (Pi-water filtration systems are popularly found in many Japanese hair salons).- Laundry doesn’t yellow as easily.SOLUTION: Pi-Mag Water Filtration System / Energy WaterEveryone should at least be drinking filtered water, preferably also water which is infused with magnetic energy from the earth, farinfrared light waves from the sun and energy from ‘space’. Water should also have organic minerals, such as coral calcium.7• Systems with water softeners, which use sodium, may be troublesome as the increased sodium may be contributing to hypertension. Typically two parts sodium extracts one part magnesium from the water.

• Roughly 2 million water filtration systems are purchased annually. Most of these have a form of carbon filter which does not address the lead deposits found in water.• 85% of Americans are deficient in calcium. We need approximately 1000 mg. Per day. Calcium is important to cellular communication, nerve functioning, heart function, bone stability and development and blood clotting ability. A system, which removes everything in the water without restoring natural substances, is shortchanging you.• Water filtration systems should have at least a 0.4-micron pore filter size to adequately remove microorganisms.• We currently know of no other filtration system, which has magnetic fields, far-infrared waves, maximum filtration, energy and the reinstatement of necessary minerals.• Once you have this technology you should drink 64 oz. per day, at least. Drink at least one glass at room temperature in the morning ½ hr before eating, 1 ½ hrs after eating and at bedtime. This helps to clear the colon, promotes regularity, strengthens the heart, oxygenates the brain, removes lipids and instills tranquility. If you are bottling water the magnetic charge will last forapprox. 3 days providing you don’t rest it against a metallic surface. It can be refrigerated. This water can be used internally as well as externally for things like cleaning eyes, bathing wounds, healing burns, preventing blistering, healing various areas, rinsing hair for maximum cleanliness and therefore growth enhancing, etc.• Not all fluids count for water intake; in fact some actually have a strong diuretic effect. Sodas, coffee, alcohol, and teas have stimulants and dehydrate the system. The CNS stimulants liberate necessary energy from the ATP storage pool. People with Alzheimer’s and children with learning disabilities should avoid caffeine. Orange juice has high potassium which promotes histamine production. It should be monitored for people with asthma, allergies, congestion, etc.• If dyspepsia is present in water, it can restore the mucosal structure; sometimes it can take as little as 10 minutes of sipping water to prevent a dyspeptic episode. Using antacids with aluminum may be contraindicated as it has been strongly implicated as a precipitating factor in Alzheimer’s, (aluminum sulfate is at times used in water purification for city water).• If you are suffering with any of the symptoms associated with water deficiency, properly hydrate yourself. In about 3 weeks you may notice a huge difference. Medications sometimes mask the symptoms of dehydration so be aware of this as well.• To assist with sleeping difficulties drink a glass of water and put a pinch of salt on the tongue, letting it dissolve naturally.

• As stated earlier, practitioners who place an emphasis on this primary component of healing and preventative care should be applauded! They are instrumental in supporting the paradigm shift, which focuses on simple solutions to deal with some major health care issues. Remember that in order to be 100% healthy you must be 100% clean on an internal level.What About Drinking Coca-Cola?1. In many states (in the USA) the highway patrol carries two gallons of Coke in the truck to remove blood from the highway after a car accident.2. You can put a T-bone steak in a bowl of coke and it will be gone in two days.3. To clean a toilet: Pour a can of Coca-Cola into the toilet bowl and .......Let the "real thing" sit for one hour, then flush clean. The citric acid in Coke removes stains from vitreous china.4. To remove rust spots from chrome car bumpers: Rub the bumper with a crumpled-up piece of Reynolds Wrap aluminum foil dipped in Coca-Cola.5. To clean corrosion from car battery terminals: Pour a can of Coca-Cola over the terminals to bubble away the corrosion.6. To loosen a rusted bolt: Applying a cloth soaked in Coca-Cola to the rusted bolt for several minutes.7. To remove grease from clothes: Empty a can of coke into a load of greasy clothes, add detergent, and run through a regular cycle. The Coca-Cola will help loosen grease stains.8. The active ingredient in Coke is phosphoric acid. Its Ph is 2.8. It will dissolve a nail in about 4 days.9. To carry Coca-Cola syrup (the concentrate) the commercial truck must use the Hazardous material place cards reserved for highly corrosive materials.10. The distributors of coke have been using it to clean the engines of their trucks for about 20 years!Water Resources and ReferencesThe following are a vast array of excerpts from reputable magazine, books, pamphlets and governmental publications date as far back as 1980 to 1997 representing the concerns of drinking water pollution and its direct affect on health. As will be immediately apparent, the seriousness of our polluted water challenges have not improved but have, in fact, increased dramatically.. Trouble On Tap (Brochure) Natural Resources Defense Council & US Public Interest Research Group, October 1995“Radioactive drinking water contaminated with radon flows from the taps and shower heads of over 19 million people at levels in excess of EPA’s proposed standard...Radioactive

drinking water contaminated with radon kills…nearly 200 people a year…’Radon has long been known to cause lung cancer in humans’ according to the Nation al Academy of Sciences…EPA has found that radon and its decay products pose significant cancer risks due to ingestion”. Consumers Digest (magazine) Special Report: “How Safe Is Your Water?” May/June 1995 Pages 65-69“Thousands of communities nationwide are facing the same problem; contamination of drinking water that isn’t fully disclosed…Some 30 million Americans were served by water systems that violated one of more public health standards in 1994, according to Carol Browner, Chief of the EPA, water regulators simply can’t keep up with an assault on all fronts. “Cryptosporidium ‘Crypto’ is naturally present in up to 87% of surface water supplies. For most healthy people, crypto is quite unpleasant, attacking the lower intestinal tract with persistent diarrhea. For the ‘Immune-compromised’ this one-celled creature can be devastating; it took an estimated 104 lives in Milwaukee and sickened 400,000. The best method of killing ‘crypto’ is filtration but 20 of the largest water systems don’t use filtration. Crypto and its larger most prevalent cousin Giardia can survive chlorination. The EPA had cited Giardia as the leading cause of waterborne illness.”. Popular SCIENCE (magazine) “How Safe Is Your Water?” October 1996, Pages 63-68“Director of the Waterborne Disease Center at the University of Connecticut Health Center says the main risk is a protozoan, Cryptosporidium parvum, which forms cysts that can cause severe intestinal problems. The EPA does not require that engineers check for Cryptosporidium, citing the cost and technical difficulty of identifying the parasite.” “Richard Mass, Director of the Environmental Quality Institute at the University of North Carolina in Asheville, heads a team that has analyzed water samples from 100,000 American homes. ‘You have a one in six chance that you are being exposed toneurologically damaging levels of lead in your tap water’.”. SELF (magazine) “Is your drinking water safe?” August 1997, pages 156-157“Approximately 50 million Americans, roughly one in five, are exposed to potentially harmful levels of hazardous materials

whenever they open their faucet...a study of tap water samples revealed that 45,000 infants were drinking reconstituted infant formula made with contaminated water. Half of those babies were swallowing four to nine chemicals in every bottle. The most recent EPA estimate is that more than 43 million Americans drink water with high lead levels.”. STATE OF THE WORLD (book) – a World Watch Institute Report on Progress Toward a Sustainable Society, Lester Brown, 1995“In developing countries, 25 million people die every year from pathogens and pollution in contaminated drinking water, and diarrhea, which causes severe dehydration and malnutrition, kills nearly 3 million children under age 5 every year and accounts for one fourth of the deaths in this age group. Humans pathogens that thrive in “aquatic” environments can cause Hepatitis A, salmonella and various diarrheal diseases that are linked to E. Coli, cholera, typhoid, and dysentery.”. MADEMOISELLE (magazine) “What’s in your water?” September 1990, page 121“No matter where you live, you can’t assume the drinking water is safe, says Brian Cohen of the Environmental Working Group. Ironically, chlorine, normally a water safety here because it kills bacteria, produces cancer-causing by-products including trihalomethanes (THMs). According to Kenneth Cantor, Ph.D., an epidemiologist with the National Cancer Institute, consuming even low levels of THMs and other chlorine by-products may, over a period of years, lead to bladder, colon, or rectal cancer. Other potential carcinogens in water include pesticides and fertilizer residues, such as nitrate and atrazine. Then there is lead: exposure to even low levels can cause elevated blood pressure and kidney damage.”. PARENTS (Magazine) “Troubled Waters” March 1996, pages 50-54“All told, 30 million Americans – roughly one in eight – are exposed to potentially harmful microbes, pesticides, lead, or radioactive radon whenever they drink a glass of tap water or take a shower, according to the EPA.”. TOXICS A TO Z (book) - A Guide to everyday Pollution Hazards, John Harle, 1991, page 57

“ The most important of these are a class of organic molecules called trihalomethanes (THMs) of which the most studied is chloroform. THMs are produced when chlorine reacts both with naturally occurring organic matter, and with industrial organic pollutants. Surface water contains more of these materials than ground water. Approximately 80% of the population receiveschlorinated water; 50% receives chlorinated surface water. Chloroform causes cancer in rats and mice.”. GOOD HOUSEKEEPING (Magazine) – “Lead in Your Drinking Water?” March 1987, Page 199“According to the EPA, as many as 40 million unsuspecting Americans may be consuming dangerously high levels of lead (heavy metal) a toxic substance – when they drink water from their faucets. Lead is thought to have the most serious effects on small children, infants, and developing fetuses. Tiny amounts are believed to alter brain development, increasing the risk of behavioral problems and learning disabilities.”. TOXICS A TO Z (Book) – A Guide to Everyday Pollution Hazards, John Harle, 1991, page 58“Lead poisoning is associated with learning impairment, reduced IQ’s and hyperactivity in children; high blood pressure in adults, and underweight and premature newborns. An estimated 10 million children receive significant amounts of lead in their drinking water.” (Page 105) “Lead cadmium, chromium, selenium, nickel, and arsenic have produced mutations in laboratory tests of human and other cells. Exposure to methyl mercury or lead at this time can cause gross deformities in development, including incorrect placement of brain structure, severe cerebral palsy, blindness, and poor or nonexistent language development. Lead exposure in children has been linked to low IQ’s.”. TIME (Magazine) Cover Story “ The Poisoning of America – Those Toxic Chemical Wastes” September 22, 1980, Page 58“ At last count, nearly 50,000 chemicals were on the market… There is a price to pay for an industrial society that has come to rely so heavily on chemicals; almost 35,000 of those used in the US are classified by the EPA as being either definitely or potentially hazardous to human health. The EPA estimates that the US is generating more than 77 billion lbs. Of hazardous

chemical wastes a year and that only 10% are being handled in a safe manner.”. TIME (Magazine) Cover Story “The Poisoning of America ’85 – Toxic Wastes” October 1985 (Same cover as 1980 issue)A letter from the publisher; “The decision to reprise the earlier cover, an unprecedented step for the magazine, was prompted by the heightened sense of urgency about the problem”. A Problem That Cannot Be Buried – The poisoning of America continues. “An environmental emergency” declared the Surgeon General in 1980. ‘A ticking time bomb primed to go off’, warned theEPA…Meanwhile fears about toxic wastes continue to grow. Each day more and more communities discover that they are living near dumps or atop ground that has been contaminated by chemicals whose once strange names and initial, dioxin, vinyl chlorine, PBB and PCB as well as such familiar toxins as lead, mercury and arsenic. THE PROBLEM IS WORSE THAN IT WASFIVE YEARS AGO.”. AMERICA THE POISONED (Book) How Deadly Chemicals are Destroying our Environment, Our Wildlife, Ourselves and HOW WE CAN SURVIVE! Lewis Regenstein, 1982, Pages 168-169Contaminating the Water – Our Nation’s Most Grievous Error – “Our ground waters are threatened by ruinous contamination. This will become the environment horror story of the 80’s…the most grievous error in judgement that we as a Nation has ever made” Eckhardt Beck, Assistant Administrator EPA, July 1980 “Repeated warnings by environmentalists for over a decade have recently been confirmed by various government studies andreports, documenting the contamination of America’s water supplies and systems with cancer causing, health destroying chemicals.”. WOMEN’S DAY (Magazine) Special Report, “Lead and Water Don’t Mix” winter 1995“The US EPA informed Americans in May 1993 that 30 million people face a potential problem with lead in their drinking water. Standard monitoring required by the Safe Drinking

Water Act (SDWA) indicated that 819 medium to large public water utilities were out of compliance with the required maximum lead ‘action level’…the dangers posed by the lead levels were highenough to pose a long-term risk to the mental development of young children.”. IS YOUR WATER SAFE TO DRINK? (Brochure) All the information you need to secure a safe, reliable supply of drinking water for you and your family – Consumer Reports Book Series 1988, Page 50 “In a national survey, lead was found to be more than 5ppb in 906 out of 1200 groundwater samples…Children are sensitive to much lower lead level. Studies have shown that infants and young children are particularly susceptible to lead poisoning,which can lead to permanent brain damage and mental retardation.”. THE SIERRA CLUB GUIDE TO SAFE DRINKING WATER (Book) Scott Alan Lewis, 1996, Page 9 “A variety of toxic chemicals, minerals and metals can contaminate drinking water supplies either as the result of natural processes of the environment or, more commonly, as the result of human activity. Among the metals and inorganic chemical contaminants that threaten drinking water supplies lead, arsenic, mercury, and cadmium are the most important. Lead is commonly used in pipes, faucets, and the solder used to join components of plumbing systems in homes and other buildings.”. USA TODAY (Newspaper) Headline “Lead Taints Blood of 77% of USA’s Population” November 14-16, 1986, Page 1 “77% of the USA’s population – including 66% of all children under 5 years old – have unsafe lead levels in their blood” states Environmental Defense Fund scientist Ellen Silbergeld.. CONSUMER REPORTS (Magazine) “Should You Use A Water Filter?” July 1997, Page 27 “Organic Chemicals in industrial and agricultural areas, herbicides and other organic compounds sometimes wind up in drinking waters. Some organic pollutants are, ironically, by-products of water chlorination systems; Chlorine combines with decaying plant matter to make chloroform and related compounds.”

. ASSOCIATED PRESS (News Release) “Chemicals in drinking water disclosed” February 11, 1988 Washington – The EPA is set to unveil requirements that FOR THE FIRST TIME will provide people with details on what chemicals are found in their drinking water.. CONSUMERS DIGEST (magazine) “Special Report: How Safe is Your Water?” June 1996 Pages 63-68 “Trichloroethylene or TCE is one of the most frequently dumped industrial solvents. TCE is believed to be a carcinogen andposes a number of other risks to humans. Various studies peg the presence of TCE in up to 34% of US water supply sources.Some ailments believed linked to TCE exposure are leukemia, bladder cancer, speech/hearing impairment, anemia, kidney/liver disorders, tumors and various diseases of the nervous system.”“Chemicals from the Tap: What’s Your Risk?”. Chlorine by-products in the water supplies of up to 100 million people are linked to an estimated 10,000 bladder cancers per year . Arsenic, a known human carcinogen is found in significant levels in the tap water of more than 50 million Americans. The radioactive gas radon, which dissolves in water, can be found in the tap water of about 80 million Americans. About 14 million people drink water contaminated with five major toxic herbicides. USA TODAY (Newspaper) Headline: “120 Million may get unsafe drinking water” September 27, 1993 Page 1 “In one of the most comprehensive drinking water studies ever, the Natural Resources Defense Council analyzed EPA records and found ‘In 1991-92, 43% of all water supplies violated federal health standards. There were 250,000 violationsaffecting more than 120 million people.’ ‘More than 900,000 people each year become ill – and as many as 900 die – from water borne disease.’ ‘State and Federal regulations acted on just 3,900 of the 250,000 violations.’ ‘Non-community water systems (hospitals, hotels and schools) had an added 40,000 violations affecting 1.1 million people.’. WATER FIT TO DRINK (Book) A Guide to the hidden hazards of drinking water and what you can do to

ensure a safe, good tasting supply for the home, by Carol Keough, 1980, page 22 “A research team from the Columbia University School of Public Health began looking into the deaths of housewives in seven New York State counties…The team, headed by Dr. Michael Alavanja, examined each female death from cancer of the gastrointestinal or urinary organs in the years 1968 to 1970…The prime suspect in these cancer deaths was chlorine…The scientists found that women in this study who drank chlorinated water ran a 44% greater risk of dying from cancer of the gastrointestinal or urinary tract than those who drank non-chlorinated water.”. SAVE YOUR LIFE (Book) What the Medical Establishment Won’t Tell You, by Michael L. Culbert, 1983, Pages 106-107 “Except for cigarette smoking, we haven’t identified anything else that accounts for potentially as much cancer as drinking water and chlorination’ according to Dr. Robert Harris, Associate Director of the toxic chemical program for the Environmental Defense Fund, a non-profit consumer group. One study funded by the federal EPA found that the death rate from cancer among those who drink chlorinated water was 44% HIGHER than among those who did not drink chlorinated water. A second study indicated an elevated cancer rate in areas where chloroform is higher. ‘Most of the dramatic decline in male potency is due to the exposure of Americans to hazardous substances. 30% appears to be due to manmade chlorinated chemicals found to contaminate the human sperm.’ Evidence from the Medical College of Georgia and the University of Arkansassuggest that between 67% and 83% of all birth defects in the nation are now caused by men. Too, research suggests that lowsperm counts are highly correlated with cancer.”. THINK BEFORE YOU DRINK (Brochure) “The Failure of the Nation’s Drinking Water System to Protect Public Health”, Natural Resources Defense Council, September 1983, Page 1. “ We must think before we drink. Few members of the public are aware that according to the most recent published review of studies of actual cancer cases in the US, a single glass of drinking water contaminants is associated with 10,700 or more bladder and rectal cancers per year – about 30 cancers per day…a recent study by the Federal Centers for

Disease Control and Prevention estimating that 940,000 people become ill each year from consuming contaminated water and that 900 of those people die each year.”. US NEWS AND WORLD REPORT (Magazine) “Just How Safe is Our Drinking Water?” January 19, 1981, Page 65.0 “The Council on Environmental Quality cited new studies linking chlorine, used to treat water consumed by about 75% of the population, with an increased cancer risk. The studies found the risk to drinkers of chlorinated water total higher by 13-93%for rectal cancer, and about 53% for colon and bladder cancer…Chlorine itself is not the culprit but rather is the organic compounds such as chloroform that result when chlorine combines with organic matter in raw water.”. US NEWS AND WORLD REPORT (Magazine “Warning: Your Drinking Water May be Dangerous” January 16, 1984, Page 51“ Chemicals, gasoline, wastes – they’re all contaminating the nation’s water supplies far worse than anyone expected. Unless action is taken quickly to stop the encroachment of these contaminants, authorities warn, the nation will face an enormous health emergency.”. GOOD HOUSEKEEPING (Magazine) “The New Fears and Facts about the Water You Drink.” February 1981, Page 201 “ A clear and present danger – some 40 to 60 million tons of dangerous chemical wastes are produced each year…careless and illegal dumping of poisonous chemical wastes has been widespread…wastes leach into streams that supply community water. Chlorination can cause pollution in itself; chlorine can react with organic matter in the water to form trihalomethanes (THMs), organic compounds such as chloroform – which if taken in excess or over a long period of time – can be harmful. THMs have been shown to cause cancer…thousands of human deaths indicate that over a lifetime chlorinated water may increase the risk of gastrointestinal cancer by up to 50-100%.”Water versus CokeWATER1. 75% of Americans are chronically dehydrated.

2. In 37% of Americans, the thirst mechanism is so weak that it is often mistaken for hunger.3. Even MILD dehydration will slow down one's metabolism as much as 3%.4. One glass of water will shut down midnight hunger pangs for almost 100% of the dieters studied in a U-Washington study.5. Lack of water, the #1 trigger of daytime fatigue.6. Preliminary research indicates that 8-10 glasses of water a day could significantly ease back and joint pain for up to 80% ofsufferers.7. A mere 2% drop in body water can trigger fuzzy short-term memory, trouble with basic math, and difficulty focusing on the computer screen or on a printed page.8. Drinking 5 glasses of water daily decreases the risk of colon cancer by 45%, plus it can slash the risk of breast cancer by 79%, and one is 50% less likely to develop bladder cancer. Are you drinking the amount of water you should every day?COKE1. In many states (in the USA) the highway patrol carries two gallons of Coke in the truck to remove blood from the highway after a car accident.2. You can put a T-bone steak in a bowl of coke and it will be gone in two days.3. To clean a toilet: Pour a can of Coca-Cola into the toilet bowl and let the "real thing" sit for one hour, then flush clean. The citric acid in Coke removes stains.4. To remove rust spots from chrome car bumpers: Rub the bumper with a rumpled-up piece of Reynolds Wrap aluminum foil dipped in Coca-Cola.5. To clean corrosion from car battery terminals: Pour a can of Coca-Cola over the terminals to bubble away the corrosion.6. To loosen a rusted bolt: Applying a cloth soaked in Coca-Cola to the rusted bolt for several minutes.7. To bake a moist ham: Empty a can of Coca-Cola into the baking pan, wrap the ham in aluminum foil, and bake. Thirty minutes before the ham is finished, remove the foil, allowing the drippings to mix with the Coke for a scrumptious brown gravy.8. To remove grease from clothes: Empty a can of coke into a load of greasy clothes, add detergent, and run through a regular cycle.The Coca-Cola will help loosen grease stains. It will also clean road haze from your windshield.For Your Info1. The active ingredient in Coke is phosphoric acid. Its pH is 2.8 (very acidic - cancer can only thrive in an acidic environment in the body). It will dissolve a

nail in about 4 days. Phosphoric acid also leaches calcium from bones and is a major contributor to the rising increase in osteoporosis.2. To carry Coca-Cola syrup (the concentrate) the commercial truck must use the hazardous material place cards reserved for highly corrosive materials.3. The distributors of coke have been using it to clean the engines of their trucks for about 20 years!Now the question is, would you like a glass of water or coke?ADD Research Studyhttp://www.cogreslab.demon.co.uk/Magnetsmed.htmFrom: cogreslab@aol.comDr. Bernard Margolis of Harrisburg, Pennsylvania, reported at the North American Academy of Magnetic Therapy in 1998 that he had treated 30 children with ADD aged 5 to 18, of whom all but two were male. 19 reported significant improvements in the first week, as judged subjectively by their best judges, the parents, one of whom said "It was like night and day with him. He was lovable with magnets and without, he was up for adoption". I carried out a study some years on a small group of hyperactive children. I discovered that these children displayed increasing severity of hyperactivity with increasing nocturnal 50Hz. electric field exposure. One might begin to formulate the hypothesis from these observations that moving electric fields are stressors, as suggested also by Martin Blank of Columbia University, NY, (Blank 1992) and that static magnetic fields are calmant. After all, what has changed on the planet with the advent of our new and convenient technologies is the A.C. electric field. The static magnetic field has always, in the guise of the gentle geomagnetic field of Mother Earth, been with us during our entire evolution. Roger Coghill

ATTENTION/BEHAVIOR ISSUES AND THE USE OF MAGNETIC PRODUCTSFrom: Dr. Barney Margolis' phone number: 717-233-4211 E-mail: docbarney@earthlink.netThe following 14 testimonials were collected by Dr. Margolis, a pediatrician for 36 years from Harrisburg, PA, who conducted an informal trial of magnetic products with a number of his patients with attention and behavior issues. The products used were Nikken’s (1) a magnetic mattress pad, (2) a magnetic pillow, and (3) a 4” round magnet, worn over the upper chest. Each patient used the products for a one week trial. The testimonials were provided by the parents. What he did was offer his patients with ATTENTION PROBLEMS the option of trying magnetics to see if they would help symptoms. They specifically did this during vacation times so it would not interfere with school work. They had the children’s parents fill out questionaires rating physical

behaviors, emotional and attention/memory before using the magnets, while on them and then when taken off of them. 28 children completed the study. The time restraint of one week was basically due to a lack of enough products. Other children were waiting to use them.Of the 28 children who completed this study 19 showed a significant improvement in scores with using magnets. These children all used one or more magnetic products. Of the children who did not respond Dr. Margolis noted that they only used one magnetic product. The question remains as to whether they would have responded if they had used them for longer than a week or used additional products. (1) “With using the magnet, Christopher’s (age 10) mood and behavior was more even throughout the day, instead of the highs and lows on medication. It was new to have him happy and not fighting with us first thing in the morning. His grandmother said that he seemed happier with the magnet. Christopher’s appetite was so much better with the magnet - he ate almost all the time!” (2) “Ian (age 11) used all three magnets: mattress pad, pillow, and disk. During use of magnets Ian appeared to be more calm, rested, and focused. They had almost an immediate effect. For example, on Saturday, Aug. 3rd, after having not used the mattress pad or pillow for one night, Ian displayed rowdy, impulsive behavior and was “out of control.” We placed the disk magnet on his shirt at lunchtime and it calmed him almost immediately. Usually when we go to a restaurant, Ian is unable to sit still and plays with anything and everything within his reach. During the trial period of using the magnets, we went out to dinner on two occasions, and he sat quietly and actually engaged in adult level conversations with us. Although he had previously been “written up” three times for poor behavior this summer by his day camp counselors, during this trial week there were no reports of misbehavior. He received another written warning last week after the trial. We are convinced that the magnets may have a positive effect on Ian’s behavior and are interested in purchasing them to continue the “experiment.” We would appreciate if you would call us with information about how we can purchase the magnets. Thanks for the opportunity to participate in the trial. (3) “Ryan (age 11) was off treatment and medicine one day post-testing (magnetic products trial), and was moving back to pre-testing behavior. Ryan was more cooperative, calm, pleasant to talk to, not argumentative, during testing. He went to bed much easier. (He recognized his own tiredness). Ryan was not a perfect child during testing. He was more typical of his age, but showed more ability to be worked with, reasoned with. He was quite willing to wear the magnet. Our trouble was withtape irritation and sweating. When Ryan is on medication, he seems suppressed, extremely calm. That is nice to have, but I don’t think that’s really our Ryan.

During testing he was not suppressed. He could wind up but we could call him on it and he knew and worked with himself more to settle down. During testing Ryan seemed more like a “normal” little boy without the attention issue that needs direction and encouragement to better his behavior.”(4) “It was like night and day with him. He was lovable with magnets, and without he was up for adoption!” (age 13) (5) “Shaun (age 9) said he didn’t feel as angry after he wore the magnets for 2 days. He told me the same thing after he was on medication for 2 days.”(6) “We started Vincent (age 5) on the mattress pad on Saturday, and by Wednesday he started to improve substantially. His concentration and manner improved, and he did not appear to be as belligerent. He was even asking for some paper to draw on a couple of times, which he rarely enjoys doing. He was able to sit for longer periods of time and work on a project, which again, rarely happens. His attitude and demeanor improved. Sometimes he gets “mouthy,” which, again, did not happen from Wednesday until about Saturday. On Sunday I took the mattress pad off. Almost immediately he was back to his “normal” self the following week.”(7) “After using the mattress pad we viewed a positive change. We feel this will be beneficial to Shannon.”(8) “Sean (age 11) used the mattress and the pillow. He was pretty much the same, but possibly a littlecalmer. When we were exasperated, I sent him to his room to rest on his bed. He seemed calmer after a rest on the magnets. I’m not sure if this is a result of the time on the magnets or the time away from stimulation. Sean would take his magnetic pillow downstairs at times to lay on it while he watched TV. There was a big increase in appetite in the beginning ... that continued through the trial.While on medication, Sean had a little trouble falling asleep at night, but not more than lots of other kids. While on the mattress, he fell asleep quickly, and did sleep in every morning.”(9) “Mike (age 7) showed no visible signs of improvement with the magnets. Please keep us informed of ANY other non-prescriptive alternative. We appreciate your concern and research.”(10) “Paul (age 39, father of Mike) ... the magnet worked very well. It allowed me to sleep soundly atnight and I was significantly more at ease during the day. The magnet reduces irritability and reduces a tendency toward impulsivity. I noticed the changes after wearing the magnet for about 4-6 hours!”(11) “Jen (age 18) went off medication for 4 days before the trial. By the 4th day I was deciding this is it. Back to medication. I didn’t even want to try the

magnet. OBNOXIOUS and BELLIGERENT, her behavior was horrible. Still eating, but very restless and moody. We persevered until Wed. 7/10.When she woke up, she took a shower and we placed the magnet on her chest and hoped for the best. By Wed. evening, things were moving slowly back to normal (whatever that may be). On Thursday she was better than the day before. Did a complete resume (wrote, typed and edited by herself, not with the usual 100 questions that needed to be asked) for a job. Totally impressed friends who have been a part of her growing up years. Thought she was a different child. Judy, my best friend and mother of 3 was amazed how much better she was in tune, focused on herself, and proud of what she had done. On Friday we went for her permit. Very proud of her, how well she was focused.”I think we are headed in the right direction. Jen seemed pleased with herself. Hoping she gets the job at the daycare. First time in a long time she has been happy about herself or anything. Jen continued wearing the magnet until 7/19. A few evenings she chose not to sleep with it on. When she woke up it was quite obvious. It took her longer to get organized and settled. Once showeredand the magnet back in place, things improved. On July 20, Jen decided no more medication; she would like to use the magnet.”(12) “To summarize my feelings about the change: previously he was highly agitated. That word best described his outlook and behavior. The mattress calmed him down considerably, enabling him to deal with matters with much more consideration. Our relationship improved substantially. By the way, I never told him about the qualities of this mattress. He only knows that I bought a new one because the old one was no longer comfortable ... the bed was expensive and I felt that buying it was a bit crazy, but it has turned out to be a great purchase. Hope it continues to provide John with the calm he needs to be more effective in life.”(13) 14 year old Thom was an angry, argumentative, impulsive boy, who was also a bed-wetter. He needed to be told many times to do his chores before they got done and homework time was very unpleasant, with lots of yelling and poor study skills. His younger siblings (ages 6 and 8) were constantly on his nerves, and the battles raged constantly. “Immediately after starting to use the ...products, and getting off of medication, the amazing changes began. In 12 days he wet his bed only twice; his mood was mostly happy. His appetite, which had been suppressed on the medication, came back wonderfully. He has become a warm, friendly child who is no longer angry at the world, and has become complimentary to his mother, and cares about her feelings. His chores are getting done willingly with no hassles; helps sometimes with the cooking and cleaning without being asked. The behavior of his siblings doesn’t bother him anymore, and he is now setting better examples for them. His maturity level has leaped forward, making it possible to have a decent conversation with him. He

actually referred to his science homework as “fun” ... his mother couldn’t believe her ears!” Due to the marvelous way he has responded to the magnets and the happiness he is experiencing, the atmosphere in the home has changed tremendously. His mother, who works full time in the family business, used to dread the time she had to go home because of the stress and tension that Thom’s behavior always caused. Now she looks forward to going home, and is marveling at her “new” son, and enjoying him tremendously.”(14) “Our 11 year old daughter had attention and impulsivity problems, and used to be on medication for those problems, and used to visit her pediatrician every 2-3 months for various reasons. In July she went off the medication and began using (magnetic) products. She has not had to return to the doctor’s office for one year for a routine physical, and has grown 4 inches, gained 15 pounds, and is doing very well in school.”Alzheimer's Research StudiesPEER-REVIEWED SCIENTIFIC STUDIEShttp://www.garynull.com/Documents/magnets.htm#1This article reports on two Alzheimer's patients who experienced significant improvement in visual memory and drawing performance following the external application of electromagnetic fields ranging from 5 to 8 Hz. Improvements were also seen in other cognitive functions, including spatial orientation, mood, shortterm memory, and social interactions.1 Noting that the disorganization of circadian rhythm (the daily biological clock) may be causally related to memory deterioration in old age and possibly to Alzheimer's disease, this article argues that the use of magnetic fields could lead to memory improvement among the elderly by means of resynchronization, or resetting, of the circadian rhythms.2Ankle Sprain Research Studyhttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESResults of this double-blind, placebo-controlled study indicated that treatment with two 30-minute sessions of noninvasive pulsed radiofrequency therapy is effective in significantly decreasing the time required for edema reduction in patients suffering from lateral ankle sprains.4

References4. A.A. Pilla & L. Kloth, "Effect of Pulsed Radio Frequency Therapy on Edema in Ankle Sprains: A Multisite Double-Blind Clinical Study," Second World

Congress for Electricity and Magnetism in Biology and Medicine, 8-13 June 1997, Bologna, Italy, p. 300.Arthritis Research Studieshttp://www.micronauts.com/magnetic.htmA formal study was reported at a Madras conference. Patients with arthritis, spondylosis, and malunion of fractures were treated with pulsed magnetic fields from .01 to 1 Hz.. The polarity and strength was not specified. Near 80% to 85% of the patients recovered and recurrence occurred in only two patients after a two year period.Other Arthritis Research StudiesPEER-REVIEWED SCIENTIFIC STUDYhttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESThis study found that 3 hours of exposure to a 50-Hz magnetic field significantly inhibited experimentally induced inflammation and suppressed arthritis in rats.5 A noteworthy American double-blind, placebo-controlled study on the effects of static magnets on the treatment of arthritis was recently published in the ®MDBR¯Journal of Rheumatology®MDNM¯ (November1997, p. 1200). The study confirms the effectiveness of magnets in relieving the pain of arthritis. Another scientific study of similar rigor is being carried out by Dr. Zimmerman, and is looking at the effects of fixed magnets on low back pain. There is good reason to expect confirmation of what users have been claiming for years--that magnets are an excellent aid to pain relief. This double-blind, placebo-controlled study examined the effects of pulsed electrical fields administered over a period of 4 weeks in the treatment of arthritis of the hand. Results showed significant clinical improvement in patients receiving the therapy relative to controls.7In this general review article on the treatment of patients with psoriatic arthritis with magnetic fields, the authors state that an alternating low-frequency magnetic field (30-40 mT) from such generators as "Polius-1" and "Polius- 101" improves the clinical state of afflicted joints. Such treatments are normally carried out for 30 minutes per day over a period of 15 to 20 days.8This study examined the effects of magnetolaser therapy either itself or in combination with conventional drugs in patients suffering from rheumatoid arthritis. Magnetolaser therapy involved the use of an AMLT-01 device and consisted of 6-minute exposures daily over a total of 14 days. Results showed a marked improvement following the first 3 days of magnetolaser therapy, with the strongest positive effects experienced by patients characterized as suffering from mild to moderate levels of the disease. At the end of the magnetolaser therapy course, 90 percent of patients showed improvement.9 This study examined the effects of low-frequency magnetic fields (from a "Polius-1"

device) in patients 7 to 14 years old suffering from juvenile rheumatoid arthritis. Treatment consisted of 10 daily exposures of 10 to 12 minutes each. Results showed beneficial effects in 58, 76, and 37 percent of patients in each of three experimental groups.10 This study examined the effects of low-frequency and constant magnetic fields in patients suffering from rheumatoid arthritis and osteoarthrosis. Low-frequency magnetic fields were shown to produce beneficial effects in patients with both stage I and II rheumatoid arthritis and with osteoarthrosis deformans, especially with respect to the wrists, knees, and ankles.11REFERENCES5. Y. Mizushima, et al., "Effects of Magnetic Field on Inflammation," Experientia, 31(12), December 15, 1975, p. 1411-1412.7. T. Zizic, et al., "The Treatment of Rheumatoid Arthritis of the Hand with Pulsed Electrical Fields," Second World Congress for Electricity and Magnetism in Biology and Medicine, 8-13 June 1997, Bologna, Italy.8. V.D. Grigor'eva, et al., "Therapeutic Use of Physical Factors in Complex Therapy of Patients with Psoriatic Arthritis," Vopr Kurortol Fizioter Lech Fiz Kult, (6), 1995, p. 48-51.9. B.Y. Drozdovski, et al., "Use of Magnetolaser Therapy with an AMLT-01 Apparatus in Complex Therapy for Rheumatoid Arthritis," Fiz Med, 4(1-2), 1994, p. 101-102.10. E.A. Shlyapok, et al., "Use of Alternating Low-Frequency Magnetic Fields in Combination with Radon Baths for Treatment of Juvenile Rheumatoid Arthritis," Vopr Kurortol Fizioter Lech Fiz Kult, 4, 1992, p. 13-17.11. V.D. Grigor'eva, et al., "Therapeutic Application of Low-Frequency and Constant Magnetic Fields in Patients with Osteoarthritis Deformans and Rheumatoid Arthritis," Vopr Kurortol Fizioter Lech Fiz Kult, 4, 1980, p. 29-35.Low Back Pain and Other Forms of Chronic PainFrom: http://www.tnp.com/encyclopedia/therapy/1/5/A double-blind, placebo controlled crossover trial of 54 individuals with knee or back pain compared an alternating polarity static magnet against a sham magnet.38 Participants used either the real or sham device for 24 hours; then, after a 7 day rest period, used the opposite therapy for another 24 hours.Evaluations showed that use of the real magnet was associated with greater improvements than the sham treatment. A double-blind placebo-controlled crossover study used alternating-pole magnets (defined in section on How to Use Magnet Therapy)on 20 individuals who had chronic low back pain for at least 6 months duration; the average length of time the participants had suffered with back pain was 19 years.6 The study found no improvement relative to the placebo group.

Pelvic Pain A double-blind placebo-controlled study of 14 women with chronic pelvic pain found no significant benefit when magnets were applied to abdominal trigger points for 2 weeks.7 However, statistical analysis showed that a larger study would have been necessary to show whether magnet therapy was effective.Benefits of FIR on Injurieshttp://www.doctorshealthsupply.com/infrared/health_facts.htmI have found several studies that suggest the benefits of using far infrared light on injuries: The American Journal of Geriatrics has published a study in which elderly patients experienced an improvement of pain and disability from degenerative osteoarthritis of the knee. A fully randomized, partially double-blind trial resulted in a pain reduction of more than 50% within the group using the therapy, whereas there was no significant improvement in the placebo group. Studies done with Magnetic Resonance Imaging suggest a more rapid recovery from muscle fatigue, as you can see in the images.Fig. 1. After 30 minutes exercise; dark parts indicate musclefatigue (due to build-up of lactic acid)Fig. 2. Instead of the usual 2-3 hours, the FAR Infrared products help muscles recover within 20 minutes only Based on my colleague's recommendation, and my curiosity, I have tried some of the products personally, and have found benefits on physical ailments, as well as emotional and athletic benefits. At this point, I had decided to look further into the explanation behind the miracle benefits.Staying healthy and youthful - beyond exercise and nutritionDr. Zane Kime, M.D., in his book "Sunlight"6 holds up the findings that sunlight exposure is similar to physical exercise in its effects on the body, as it improves the balance of blood pressure, blood sugar, and an increase in oxygen in the cells, muscle strength, vitality and mental stability. Natural spectrums of light found in sunlight, for example, are essential for bone growth as well as preventing osteoporosis, regulating hormonal functions as well as immune functions. It has occurred to me that light may be a great help to patients who cannot exercise, because of health reasons, age, or lifestyle inhibitions.The Anti-Aging FactorAs we age, we all experience a shift in our hormones, and researchers now feel this change is responsible for many of the maladies we associate with aging, such as menopause, sleeplessness, fatigue, arteriosclerosis, and others. In his research in Pennsylvania at the Thomas Jefferson Medical School, Dr. George Brainard has stated that light affects the hormonal balance of the body, in levels of melatonin, prolactin, cortisone, testosterone, TS4, LH, FSH, T3, and thyroid hormones. John Ott, a modern pioneer in this subject, attributes these affects to a process similar to the photosynthesis process in plants. In this process, light is

converted by the body into electrochemical impulses that are sent to the pineal and pituitary glands, which send the hormones through the body's central nervous system to all the cells of the body. The hormones affected through this process and the functioning of these glands are the growth hormone, thyroid hormone(TSH), adrenocorticotropic hormone (ACTH), prolactin, oxytoxin, melanocyte stimulating hormone (MSH), and anti-diuretic hormone. Therefore, light is essential to the functioning of our entire endocrine system.7 As hormone replacement has mixed results at times, it is possible that in the future, doctors will prescribe light for therapy, in forms such as the FAR Infrared wraps.Common problems associated with lifestyle and aging, such as hypertension and osteoporosis, headaches and digestive problems, are attributed by some scientists to be the result of excess acidity in our system.The American Medical Journal found that in patients with bone loss, alkalizing their system caused a decrease in bone loss. Their conclusion was that our typical American diet is acid-producing.8 The acids deposited in our blood are often stored by the body in forms of cholesterol, fatty acid, uric acid, and othervillains that cause havoc in our system.9 Sang Whang, the author of "Reverse Aging" claims that these excess acids can be eliminated with the use of far infrared products, along with consuming certain alkaline minerals and foods.10 The far infrared resonance heats up the internal temperature of the body, increasing circulation, thus enabling the blood to melt out the acidic toxins that have been deposited for years in one's arteries. A study done on carotid artery buildup showed an increase in blood flow within the artery after two nights of the subject sleeping on the FAR Infrared mattress, for an average of 10 hours a night.11 As a doctor, I cannot recommend the wraps, as they are not FDA approved in this country as therapies for these particular maladies. However, if I were personally a sufferer of hypertension, or chronic arthritis, or any systemic problem, I would use the FAR Infrared mattress or wraps for my own health.Negative IonsThe other element contained within the FAR Infrared technology that I investigated was the negative ions that were claimed to increase with the use of it. Nature's "life enhancing particles", negative ions, are molecules with an extra electron, discovered in 1899 by two scientists named Elster and Geitel. Mice live longer in certain cases when exposed to negative ions. They have been linked to killing germs, and preventing infections. Dr. Igho Hart Kornblueh, a physician, found that patients recovered 57% faster from surgery when exposed to large doses of negative ions. It has also been found that negative ions seem tohelp with allergies, migraines, and sinus problems.12 Although negative ions are plentiful in nature (occurring at almost twice the amount near the ocean or

waterfalls as normal), our environment is sadly lacking these energetic boosters. Dr. William Rea, Chief of surgery at Brookhaven Medical Center in Texas, states that "Most houses don't breathe like they used to". Steel and concrete absorb most of the available negative ions in the atmosphere, and plastics have a positive static charge, so that the amount of negative ions that we receive is extremely minimal. Emotional problems? Blame it on the ions, or the lack of them. The opposite of negative ions, positive ions, are particles with a missing electron. In certain courts, the issue of winds that bring in positive ions has beenused as an excuse for erratic and criminal behavior. On the contrary, negative ions promote alpha brain waves, creating a calming effect. Dr. Albert P. Krueger, an American scientist well respected for his extensive work with ions, discovered that negative ions affect the rate at which serotonin is oxidized in thebloodstream. Serotonin is secreted by the pineal glands and intestines, and affects sleep, mood, nerveimpulses, blood-clotting, and contraction of smooth muscles. It is most popularly associated with feelings of security, peace, and satisfaction. Negative ions have been shown to reduce neurosis and anxiety.13 This may explain why so many people sing in the shower, or why one can't seem to fully wake up without one. When the water falls in the shower, it creates negative ions. Negative ions are also found plentifully around waterfalls and oceans. Vasil'yev, a Russian ion pioneer, showed in the 1970's that ions act on the endings of pulmonary afferent nerve fibers, and alter the functional state of the central nervous system, and through it, the peripheral organs The FAR Infrared material that I research also was shown to increase the rate of negative ions. This should be a relief for all of us who don't live or work at waterfalls or on the ocean shore. The people that I interviewed seemed to notice the calming effect of wearing the wraps, although they weren't told of this effect prior to wearing them.As I approach my upper years, I am elated to use technology such as this to enhance my daily life, and increase my chances of living healthy long past my 90th birthday. I hope that you have the same opportunity.Bone Fracture Research Studieshttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESThis study examined the effects of bone grafting and pulsed electromagnetic fields on a group of 83 adults with ununited fractures. Results showed a successful healing rate of 87 percent in the 38 patients originally treated with bone grafts and PEMF for ununited fractures with wide gaps, synovial pseudarthrosis, and malalignment. A healing rate of 93 percent was shown among the 45 patients who had initially been unsuccessfully treated with PEMF alone and had bone-grafting and were re-treated with pulsing electromagnetic fields.

14 This study examined the effects of pulsing electromagnetic fields on 125 patients suffering from ununited fractures of the tibial diaphysis. Results showed a healing rate of 87 percent.15 Results of this study showed treatment with pulsed electromagnetic fields resulted in an overall success rate of at least 75 percent inpatients suffering from tibial lesions.16 This review article makes the following observations with respect to the use of pulsed electromagnetic fields in treating ununited fractures, failed arthrodeses, and congenital pseudarthroses. The treatment has been shown to be more than 90 percent effective in adult patients. In cases where union does not occur with PEMFs alone after approximately four months, PEMF treatment coupled with fresh bone grafts ensures a maximum failure rate of only 1 to 1.5 percent. For those with delayed union three to four months following fracture, PEMFs appear to be more successful than in patients treated with other conservative methods. For more serious conditions, including infected nonunions, multiple surgical failures, long-standing atrophic lesions, failed knee arthrodeses after removal of infected prostheses, and congenital pseudarthroses, PEMF treatment has exhibited success in most patients.17 Results of this study found that 35 of 44 nonunited scaphoid fractures 6 months or older healed in a mean time of 4.3 months during pulsed electromagnetic field treatment using external coils and a thumb spica cast. 18This double-blind, placebo-controlled study examined the effects of pulsed electromagnetic fields in femoral neck fracture patients undergoing conventional therapy. PEMF treatment was started within two weeks of fracture, and patients were instructed to make use of the electromagnetic device for 8 hours per day over a 90-day period. Results showed beneficial effects relative to controls after 18 months of follow-up.19 This review article on pulsing electromagnetic fields in the treatment of bone fracture observes that the surgically noninvasive outpatient method approved by the FDA in 1979 produced confirmed end results in 1007 ununited fractures and 71 failed arthrodeses, with an overall success rate at Columbia-Presbyterian Medical Center of 81 percent; an international success rate of 79 percent, and asuccess rate with other patients in the U.S. of 76 percent.22 Results of this double-blind study showed significant healing effects of low-frequency pulsing electromagnetic fields in patients treated with femoral intertrochanteric osteotomy for hip degenerative arthritis.25 In this study, 147 patients with fractures of the tibia, femur, and humerus who had failed to benefit from surgery received treatment with external skeletal fixation in situ and pulsed electromagnetic fields. Results indicated an overall success rate of 73 percent. Femur union was seen in 81 percent and tibia union in 75 percent\

26 This study examined the effects of extremely-low-frequency electromagnetic fields (1-1000 Hz, 4 gauss) on new bone fractures of female patients. Results led the authors to suggest that EMF treatment accelerates the early stages of fracture healing.27 This study examined the preventive effects of low-frequency pulsing electromagnetic fields against delayed union in rat fibular osteotomies and diaphyseal tibia fractures in humans. Results indicated such treatment modulated and accelerated fracture union in both groups29 This article discusses the cases of two children with bone malunion following lengthening of congenitally shortened lower legs. Pulsed sinusoidal magnetic field treatment was beneficial for both patients.30 Results of this study showed that 13 of 15 cases of long-bone nonunion treated with pulsed electromagnetic fields in combination with Denham external fixator united within several months.31 Results of this study found electromagnetic field stimulation to be an effective treatment for nonunion among a group of 37 French patients.32 Results of this study found treatment induced pulsing to be beneficial in patients suffering from nonunions unresponsive to surgery.33 In this interview with Dr. C. Andrew L. Bassett, a physician researching the use of pulsed electromagnetic fields for the past 30 years at Columbia University's Orthopedic Research Lab, Dr. Bassett notes that approximately 10,000 of the 12,000-plus orthopedic surgeons in the U.S. have used pulsed electromagnetic fields on at least one patient. Many such surgeons have incorporated the therapy on a more regular basis. He estimates that a total of at least 65,000 patients nationwide have received the treatment, with a probable success rate of between 80 and 90 percent. Use of the treatment has been primarily in patients suffering from nonunited fractures, fusion failures, and pseudoarthrosis 34 Results of this study showed pulsed electromagnetic fields to have beneficial healing effects in patients suffering from difficult to treat and surgically resistant bone nonunions.35 This review article notes that the use of pulsed electromagnetic fields began in 1974, and that 250,000 nonunion patients have received the treatment since. The author argues that success rates are comparable to those of bone grafting, and that PEMF treatment is more cost-effective and free of side effects. The FDA approved PEMF use in 1982, although it remains widely unused due to physician misunderstanding and lack of knowledge concerning the treatment 36 This 7-year study examined data on more than 11,000 cases of nonunions treated with pulsed electromagnetic fields for up to 10 to 12hours per day. Results indicated an overall success rate of 75 percent.

37 This study examined the effects of low-frequency electromagnetic fields (1-1000 Hz) on middle-aged female patients suffering from fresh radius fractures. Results showed significant increases in scintimetric activity surrounding the fracture area after two weeks of EMF treatment relative to controls.38 This study examined the effects of constant magnetic fields in patients suffering from fractures. Results showed that magnetic exposure reduced pain and the onset of edema shortly after trauma. Where edema was already present, the treatment exhibited marked anti-inflammatory effects. The strongest beneficial effects occurred in patients suffering from fractures of the ankle joints.39 Results of this study found that 10 hours per day of electromagnetic stimulation (1.0-1.5 mV) produced complete union in 23of 26 patients receiving the treatment for nonjoined fractures.40 This review article looks at the history of pulsed electromagnetic fields as a means of bone repair. The author argues that success rates have been either superior or equivalent to those of surgery, with PEMF free of side effects and risk.41References14. C.A. Bassett, et al., "Treatment of Therapeutically Resistant Non-unions with Bone Grafts and Pulsing Electromagnetic Fields," Journal of Bone Joint Surg, 64(8), October 1982, p. 1214-1220.15. C.A. Bassett, et al., "Treatment of Ununited Tibial Diaphyseal Fractures with Pulsing Electromagnetic Fields," Journal of Bone Joint Surg, 63(4), April 1981, p. 511-523.16. M.W. Meskens, et al., "Treatment of Delayed Union and Nonunion of the Tibia Pulsed Electromagnetic Fields. A Retrospective Follow-up," Bull Hosp Jt Dis Orthop Inst, 48(2), Fall 1988, p. 170-175.17. C.A. Bassett, "The Development and Application of Pulsed Electromagnetic Fields (PEMFs) for Ununited Fractures and Arthrodeses," Clin Plast Surg, 12(2), April 1985, p. 259-277.18. G.K. Frykman, et al., "Treatment of Nonunited Scaphoid Fractures Pulsed Electromagnetic Field and Cast," Journal of Hand Surg, 11(3), May 1986, p. 344-349.19. E. Betti, et al., "Effect of Electromagnetic Field Stimulation on Fractures of the Femoral Neck. A Prospective Randomized Double-Blind Study," Second World Congress for Electricity and Magnetism in Biology and Medicine, 8-13 June 1997, Bologna, Italy.22. C.A. Bassett, et al., "Pulsing Electromagnetic Field Treatment in Ununited Fractures and Failed Arthrodeses," JAMA, 247(5), February 5, 1982, p. 623-628.

25. G. Borsalino, et al., "Electrical Stimulation of Human Femoral Intertrochanteric Osteotomies. Double-Blind Study," Clin Orthop, (237), December 1988, p. 256-263.26. M. Marcer, et al., "Results of Pulsed Electromagnetic Fields (PEMFs) in Ununited Fractures after External Skeletal Fixation," Clin Orthop, (190), November 1984, p. 260-265.27. O. Wahlstrom, "Stimulation of Fracture Healing with Electromagnetic Fields of Extremely Low Frequency (EMF of ELF)," Clin Orthop, (186), June 1984, p. 293-301.29. G. Fontanesi, et al., "Slow Healing Fractures: Can They be Prevented? (Results of Electrical Stimulation in Fibular Osteotomies in Rats and in Diaphyseal Fractures of the Tibia in Humans)," Italian Journal of Orthop Traumatol, 12(3), September 1986, p. 371-385.30. F. Rajewski & W. Marciniak, "Use of Magnetotherapy for Treatment of Bone Malunion in Limb Lengthening. Preliminary Report," Chir Narzadow Ruchu Ortop Pol, 57(1-3), 1992, p. 247-249.31. R.B. Simonis, et al., "The Treatment of Non-union Pulsed Electromagnetic Fields Combined with a Denham External Fixator," Injury, 15(4), January 1984, p. 255-260.32. L. Sedel, et al., "Acceleration of Repair of Non-unions Electromagnetic Fields," Rev Chir Orthop Reparatrice Appar Mot, 67(1), 1981, p. 11-23.33. J.C. Mulier & F. Spaas, "Out-patient Treatment of Surgically Resistant Non-unions Induced Pulsing Current - Clinical Results," Arch Orthop Trauma Surg, 97(4), 1980, p. 293-297.34. C.A. Bassett, "Conversations with C. Andrew L. Bassett, M.D. Pulsed Electromagnetic Fields. A Noninvasive Therapeutic Modality for Fracture Nonunion (Interview)," Orthop. Review, 15(12), 1986, p. 781-795.35. B.T. O'Connor, "Treatment of Surgically Resistant Non-unions with Pulsed Electromagnetifc Fields," Reconstr Surg Traumatology, 19, 1985, p. 123-132.36. A. Bassett, "Therapeutic Uses of Electric and Magnetic Fields in Orthopedics," in D.O. Carpenter & S. Ayrapetyan, (eds.), Biological Effects of Electric and Magnetic Fields. Volume II: Beneficial and Harmful Effects, San Diego: Academic Press, 1994, p. 13-48.37. A.A. Goldberg, "Computer Analysis of Data on More than 11,000 Cases of Ununited Fracture Submitted for Treatment with Pulsing Electromagnetic Fields," Bioelectrical Repair and Growth Society, Second Annual Meeting, 20-22 September 1982, Oxford, UK, p. 61.38. O. Wahlstrom, "Electromagnetic Fields Used in the Treatment of Fresh Fractures of the Radius," Bioelectrical Repair and Growth Society, Second Annual Meeting, 20-22 September 1982, Oxford, UK, p. 26.

39. G.B. Gromak & G.A. Lacis, "Evaluations of the Efficacy of Using a Constant Magnetic Field in Treatment of Patients with Traumas," in I. Detlav, (ed.), Electromagnetic Therapy of Injuries and Diseases of the Support-Motor Apparatus. International Collection of Papers, Riga, Latvia: Riga Medical Institute, 1987, p. 88-95.40. A.F. Lynch & P. MacAuley, "Treatment of Bone Non-Union Electromagnetic Therapy," Ir Journal of Med Sci, 154(4), 1985, p. 153-155.41. C.A.L. Bassett, "Historical Overview of PEM-Assisted Bone and Tissue Healing," Bioelectromagnetics Society, 10th Annual Meeting, 19-24 June 1988, Stamford, CT, p. 19.Brain Injuries Research Studieshttp://www.micronauts.com/magnetic.htmAt a Madras conference reported were 100 cases who were divided into two groups: one received pulsed magnetic field treatments and the others didn't. The first group showed improvement by clinical assessments and CT scans. The treatments appeared to show an increase in sodium ion flow, reduction in swelling, and a speed-up of tissue repair (compared to normal).Bronchitis Research Studyhttp://www.cogreslab.demon.co.uk/Magnetsmed.htmWith bronchitis static magnets can play a much greater role than is currently the case in conventional medical practice. 24 children aged 5-6 years suffering from chronic bronchitis were exposed to static magnets of 100-300 gauss for 3 hours and for 30 sessions. These were compared with a 16-child control group. In the exposed group cough and dyspnoea decreased and there was a comparable improvement as measured by pneumotachography compared with controls (Yashchenko et al., 1988). Other paediatric studies on patients with Perthes disease using static magnets of 200-400 gauss for up to 24 hours and over periods from 40 days to 6 months reported improvement in hip mobility, analgesic effects, and in the post exposure periods these improvements continued (Degen et al., 1977; Dolganova, Dolganov et al., 1985).Cancer Studieshttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESResults of this study found that prolonged exposure to a 7-tesla uniform static magnetic field for a period of 64 hours inhibited growth of three human tumor cell lines in vitro.43 This study examined the effects of a rotational magnetic field on a group of 51 breast cancer patients. Results showed a significant positive response in 27 of them.44Results of this study indicated that exposure to a rotational magnetic field inhibited Walker's carcinoma tumor growth as much as 90 percent in some cases

.45 Results of this study indicated that pulsed magnetic field stimulation increased the incorporation of antitumor agents into cells, and thus increased antitumor activity shifting the cell cycle to a proliferative from a nonproliferative phase46 Results of this study found that 20-30 sessions of magnetotherapy administered preoperatively exhibited antitumor effects in patientssuffering from lung cancer.47This study examined the effects of microwave resonance therapy (MRT) in patients suffering from various forms of cancer. Results showed that MRT treatment prior to surgery reduced the spread of cancer-associated conditions and reduced the risk associated with surgery in 87 percent of patients. MRT applied postoperatively had beneficial effects in 68 percent.50 Results of this study proved that the combination of weak pulsed electromagnetic fields with antioxidant supplementation is beneficialin the treatment of patients suffering from tongue cancer, improving speech, pain control, and tolerance to chemotherapy51 Results of this controlled study indicated that treatment with a constant magnetic field significantly improved long-term (3-year) survival time in patients undergoing radiation therapy for cancer of the throat. Constant magnetic field therapy consisted of the application of 300 mT for 30 minutes to tumor and metastasizing regions immediately prior to each irradiation.52 Results of this Russian study indicated that the use of whole body eddy magnetic fields, coupled with more conventional cancer therapies (including magnetotherapy) is effective in the treatment of patients suffering from a variety of different malignancies.53 This article reports on the case of a 48-year-old-woman with breast cancer who was treated successfully with magnetotherapy. Infiltration showed a marked decrease following 30 whole body exposures to an eddy magnetic field for 60 minutes. One metastatic node disappeared while the size of others was reduced following 60 such exposures. A total regression of tumor and metastases was seen following the completion of a course of 110 exposures.54 This study examined the effects of whole body magnetic fields (16.5-35 G, 50-165 Hz) on patients suffering from different forms ofcancer. Treatment consisted of 15 cycles, each 1-20 minutes in duration, and was coupled with more traditional cancer therapies. Results showed that the magnetotherapy had overall beneficial effects, particularly with respect to improved immune status and postoperative recovery.55

References

43. R.R. Raylman, et al., "Exposure to Strong Static Magnetic Field Slows the Growth of Human Cancer Cells in Vitro," Bioelectromagnetics, 17(5), 1996, p. 358-3 3.44. N.G. Bakhmutskii, et al., "The Assessment of the Efficacy of the Effect of a Rotational Magnetic Field on the Course of the Tumor Process in Patients with Generalized Breast Cancer," Sov Med, (7), 1991, p. 25-27.45. N.G. Bakhmutskii, et al., "The Growth Dynamics of Walker Carcinosarcoma During Exposure to a Magnetic Eddy Field," Vopr Onkol, 37(6), 1991, p. 705-708.46. Y. Omote, "An Experimental Attempt to Potentiate Therapeutic Effects of Combined Use of Pulsing Magnetic Fields and Antitumor Agents," Nippon Geka Gakkai Zasshi, 89(8), August 1988, p. 1155-1166.47. L.S. Ogorodnikova, et al., "Morphological Criteria of Lung Cancer Regression Under the Effect of Magnetotherapy," Vopr Onkol, 26(1), 1980, p. 28-34.50. D.V. Miasoedov, et al., "Experience with the Use of Microwave Resonance Therapy as a Modifying Factor in Oncological Therapy," Abstracts of the First All-Union Symposium with International Participation, May 10 13, 1989, Kiev, Ukraine, p. 313-315.51. U. Randoll & R.M. Pangan, "The Role of Complex Biophysical-Chemical Therapies for Cancer," Bioelectrochem Bioenerg, 27(3), 1992, p. 341-346.52. V.G. Andreev, et al., "Radiomodifying Effect of a Constant Magnetic Field in Radiation Therapy of Patients with Cancer of the Throat," Fizicheskaia Meditzina, 4(1-2), 1994, p. 92.53. V. Smirnova, "Anti-Tumorigenic Action of an Eddy Magnetic Field," Vrach, 2, 1994, p. 25-26.54. N.G. Bakhmutskii, et al., "A Case of Successful Treatment of a Patient with Breast Cancer Using a Rotating Electromagnetic Field," Soviet Medicine, 8, 1991, p. 86-87.55. V.A. Lubennikov, et al., "First Experience in Using a Whole-Body Magnetic Field Exposure in Treating Cancer Patients," Vopr Onkol, 41(2), 1995, p. 140-141.Magnets, Acupressure Studied to Ease Cancer Therapy 'Hot Flashes'http://www.mc.vanderbilt.edu/reporter/index.html?ID=859Hot flashes, a well-known symptom of menopause, can be a very bothersome side effect of treatment for many breast cancer survivors- and one with few good options for relief.Now, a Vanderbilt University School of Nursing researcher in the Vanderbilt-Ingram Cancer Center is taking a cue from Chinese medicine in an effort to develop a safe, effective strategy to ease cancer therapy-induced hot flashes.

Janet S. Carpenter, Ph.D., assistant professor of Nursing, is investigating magnetic devices placed on strategic acupressure points to gauge their potential ability to relieve hot flashes - periods of overheating, sweating and flushing triggered by fluctuations in hormone levels."Almost two-thirds of women who have been treated for breast cancer have hot flashes," said Carpenter, who published a paper in the journal Cancer last year documenting the prevalence and severity of hot flashes among breast cancer survivors. "In our study, 65 percent said they'd experienced hot flashes in the previous two weeks. In addition, 59 percent said they were extremely severe and 44 percent said they were extremely bothered by them."Using a 24-hour monitoring device, Carpenter and her colleagues at the University of Kentucky also found that women experienced hot flashes throughout the night. Some breast cancer survivors experienced seven to eight hot flashes each night."Even if these women do not wake up, their sleep is probably being disturbed," said Carpenter, who joined Vanderbilt's School of Nursing and Cancer Center last August. "Fatigue can be a significant side effect of cancer treatment. Hot flashes, and the sleep disruption that results, could contribute to that fatigue as well as lead to feelings of depression." Menopausal symptoms including hot flashes but night sweats, vaginal dryness, sleep disturbances and mood alteration are also a significant problem for patients, said Dr. Brenda P. Nicholson, assistant professor of Medicine and breast cancer specialist in theVanderbilt-Ingram Cancer Center. Carpenter's research, which is also aimed at learning more about intensity, initiation and duration of hot flashes among breast cancer survivors, will be very helpful in better defining the extent of the extent of the problem, Nicholson said. In menopause, hot flashes are triggered by natural hormonal fluctuations that occur as the ovaries stop producing the female hormone estrogen. For pre-menopausal breast cancer survivors, hot flashes may be the result of early artificial menopause triggered by chemotherapy and/or radiation therapy. In addition, many women with breast cancer also take the estrogen-like drug tamoxifen for five years after completion of their initial treatment in an effort to prevent cancer recurrence. Tamoxifen commonly causes hot flashes. For healthy women, menopausal symptoms are often alleviated with hormone replacement therapy. However, hormone replacement is not generally recommended for women with a history of breast cancer because of concern that it will increase the risk of recurrence. "Alternatives to hormone replacement, such as plant estrogens, are not well-researched for their safety in any women, but particularly in this group," Carpenter said. Other researchers at Vanderbilt Medical Center have demonstrated effectiveness of magnetic therapy in the treatment of chronic pain

and nausea, Carpenter said, adding that in those cases, placement of the magnets has correlated with acupressure points for those symptoms."There are also acupressure points for hot flashes," she said. "Magnetic therapy has not been studied in the treatment of hot flashes before, but magnetic devices really have no negative side effects in comparison to medications. We also suspect, based on the pain research, that they will act quickly, in a matter of hours. Some medications for hot flashes take three or four weeks to take effect."The Vanderbilt-Ingram Cancer Center is funding the pilot study, which will compare the experiences of 20 women using two different magnetic devices. VUMC's Institutional Review Board, which must authorize any research involving patients, has approved the study. To be eligible, women must have completed or be completing first-time treatment for breast cancer and experiencing hot flashes. After a 24-hour monitoring period, participants will wear six of one type of magnetic devices on acupressure points on their ankles,lower abdomen and lower back for three days, followe by a post-treatment measurement. After a 10-day resting period, they will switch to the other device and follow the same routine. Carpenter is also conducting a survey of 70 breast cancer survivors to learn more about the initiation, duration and intensity of hotflashes. She is recruiting healthy women, ages 50-80, to complete the survey as a comparison group. Women will each receive $5 to complete the survey and return it by mail. The survey takes about 30 minutes to complete, and any ofthe healthy women who are experiencing hot flashes will be asked to keep a two-day diary of their symptoms. To learn more about the intervention study or to participate in the survey, contact Janet Carpenter at 322-0282 or the Vanderbilt- Ingram Cancer Center Information Program at 1-800-811-8480.Cardiovascular/Coronary Heart DiseasePEER-REVIEWED SCIENTIFIC STUDYhttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESResults of this study found that the addition of magnetotherapy to the treatment of patients suffering from ischemic heart disease and osteochondrosis led to clinical improvements.57 Results of this study involving 23 parasystolic children found that low-frequency magnetic field exposure improved humoral and cellular processes involved in the regulation of cardiac rhythm.58 The authors of this study report on their development of a polymagnetic system called Avrora-MK-01 used to administer impulse magnetic fields to diseases of the leg vessels. Results indicated positive effects on peripheral capillaries in 75-82 percent of patients receiving the treatment at a pre-gangrene stage.59 Results of this study showed exposure to low-frequency alternating magnetic fields had beneficial effects in children with primary arterial hypertension, as seen in the attenuation of sympathetic and vagotonic symptoms.60 this study demonstrated

that traveling pulsed magnetic field and magnetic laser treatment produced beneficial effects in patients uffering from the initial stages of essential hypertension.61 n this article, the authors propose a new approach to treating atherosclerosis through the alteration of biophysical properties both ntracellularly and extracellularly. Citing their own preliminary data, they suggest atherosclerotic lesions might be selectively resolved ithout harming normal blood vessels allowing the lesions to take up the magnetically excitable submicron particles and then pplying an external alternating electromagnetic field.62 his study examined the effects of constant MKM2-1 magnets on essential hypertension patients. Results indicated the treatment ecreased arterial pressure in stage II patients, with magnetotherapy being shown to produce beneficial effects on the central emodynamics and microcirculation.63 esults from several recent studies conducted the author are reviewed. Conclusions are that pulsed electromagnetic fields exhibit rotective effects against necrosis from acute ischemia in rats, cerebral infarcts in rabbits, and myocardium infarcts in rats.64 his study examined the effects of extremely high frequency electromagnetic radiation (EHF EMR) in 93 patients suffering ischemic eart disease. EHF treatment consisted of 10 to 15 exposures of the lower end of the sternum from a 'Yav'-1-7,1 device. Treatment as performed five times weekly for a total of 30 minutes per day, with drug therapy being maintained during this period. Positive esults tended to occur after 5 to 6 treatment sessions, with a good or satisfactory response being reported in 82 of 93 patients, and asting as long as 11 months after hospital release.65 his review article concerning the clinical application of electromagnetic fields notes that microwave therapy has been shown to mprove local circulation and vascular tone, increase the volume of functional capillaries, lower hypertension, stimulate protein and arbohydrate metabolism, stimulate the pituitary-adrenal system, produce anti-inflammatory effects, and improve digestive organ unction. Studies have shown decimeter wave therapy capable of stimulating the secretory function of the stomach, as well as blood irculation, respiratory function, and the immune system. Side effects have been reported in both human and animal studies.67 n this study, 30 myocardial infarction patients received millimeter-wave (MW) therapy in the form of 10 exposures of 30 minutes per ay, with a 2-day interruption after the fifth exposure. Patients continued conventional drug treatment during the MW therapy period. etter results were seen in those patients exposed to the MW therapy relative to an equal number of patients receiving conventional reatment only.68 his study examined the effects of millimeter wave therapy in approximately 450 patients suffering from a variety of diseases, ncluding those of the musculoskeletal, digestive, pulmonary, and nervous systems. Treatment consisted of 25-30 minutes per day sing the "Porog-1" apparatus and generally lasted for a period of up to 10 days. Results showed positive effects in over 87

percent of he patients.69 esults of this study found that the use of magnetophore therapy (constant magnets applied to adrenal regions 10 hours per day for 15days) significantly improved symptoms associated with hypertension in about 35 percent of patients studied, with mild improvement een in 30 percent, and no improvement in 35 percent. Patients receiving decimeter-band waves (460 MHz, field intensity of 35-45 W, or 10-15 minutes per day for a total of 15 days) experienced similar results.70 esults of this placebo-controlled study demonstrated a 76-percent effectiveness rate for running impulse magnetic field therapy in a roup of arterial hypertensive patients. Treatment consisted of two 25-minute exposures per day over a period of 10-20 total xposures, at frequencies of 10 or 100 Hz and magnetic field intensity of 3 or 10 mT.71 this study examined the efficacy of the reinfusion of autologous blood following magnetic field exposure in hypertensive patients. Positive effects were found in 92 percent of patients receiving the treatment.73 This double-blind, placebo-controlled study examined the effects of magnetotherapy in patients suffering from first- or second-stage hypertension. A magnetic field of 50 Hz, 15-25 mT was applied to acupuncture points He-Gu and Shen'-Men for 15-20 seconds perday for a total of 9-10 days. Results: The treatment improved headaches in 88 percent of patients, dizziness in 89 percent, and irritability in 88 percent. In general, 95 percent of hypertensive patients experienced beneficial effects from the treatment, and the morbidity rate decreased twofold following one course extended over a period of 5-6 months.74 This placebo-controlled study examined the effects of constant and of running magnetic fields in patients suffering from stage II hypertension. Results found that constant magnetic fields exhibited benefits in 68 percent of patients treated, and running magneticfields were helpful in 78 percent. Only 30 percent of controls showed improvement. Constant magnetic field treatment consisted of constant magnets applied to the inner side of the wrist on each hand for 35-40 minutes daily over a period of 7-10 days. Running magnetic field treatment involved the use of a "Alimp-1" apparatus for 20 minutes per day for a total of 12-15 days.76 This double-blind, placebo-controlled study found that magnetotherapy was effective in the treatment of symptoms associated with stage II hypertension, such as headache, dizziness, and cardiodynia. The therapy consisted of permanent circular magnets (16 mT) applied to the inner forearm for 30-45 minutes per day over a period of 10 sessions.77 This controlled study examined the effects of magnetotherapy in patients suffering from neurocirculatory hypotension (low blood pressure) or hypertension (high blood pressure). Treatment consisted of a running pulsed magnetic field generated an "ALIMP" device (0.5 mT, 300 Hz) administered for 20 minutes per day over a course of 10 days. Patients suffering from hypotension did not benefit significantly from the magnetotherapy. Hypertension patients, however, showed a marked improvement with respect to

symptoms including headache, chest pain, extremity numbness, abnormal systolic and diastolic blood pressure, and work capacity.80 This double-blind, placebo-controlled study found that low-frequency, low-intensity electrostatic fields (40-62 Hz) administered for 12-14 minutes per day helped normalize blood pressure in patients suffering from hypertension.81 This study examined the effects of low-frequency alternating magnetic fields in patients suffering from arteriosclerosis or osteoarthrosis deformans. Treatment involved 10-15 minute daily leg exposures over a total of 15 days. Results showed the treatment to be effective in 80 percent of arteriosclerosis patients and 70 percent of those with osteoarthrosis deformans.82 This study examined the effects of low-frequency magnetic fields (25 mT) in patients suffering atherosclerotic encephalopathy. Treatment involved 10-15 minute daily exposures over a total of 10-15 applications. Results showed clinical improvements with respect to chest pain, vertigo, headache, and other symptoms.83 References 57. M.A. Dudchenko, et al., "The Effect of Combined Treatment with the Use of Magnetotherapy on the Systemic Hemodynamics of Patients with Ischemic Heart Disease and Spinal Osteochondrosis," Lik Sprava, (5), May 1992, p. 40-43. 58. E.M. Vasil'eva, et al., "The Effect of a Low-frequency Magnetic Field on Erythrocyte Membrane Function and on the Prostanoid Level in the Blood Plasma of Children with Parasystolic Arrhythmia," Vopr Kurortol Fizioter Lech Fiz Kult, (2), March-April 1994, p. 18-20. 59. Y.B. Kirillov, et al., "Magnetotherapy in Obliterating Vascular Diseases of the Lower Extremities," Vopr Kurortol Fizioter Lech Fiz Kult, (3), May-June 1992, p. 14-17.60. O.M. Konova & M.A. Khan, "The Effect of a Low-frequency Alternating Magnetic Field on the Autonomic Nervous System in Children with Primary Arterial Hypertension," Vopr Kurortol Fizioter Lech Fiz Kult, (2), March-April, 1996, p. 8-10.61. V.S. Zadionchenko, et al., "Prognostic Criteria of the Efficacy of Magnetic and Magnetic-laser Therapy in Patients with the Initial Stages of Hypertension," Vopr Kurortol Fizioter Lech Fiz Kult, (1), January-February 1997, p. 8-11.62. R.T. Gordon & D. Gordon, "Selective Resolution of Plaques and Treatment of Atherosclerosis Biophysical Alteration of "Cellular" and "Intracellular" Properties," Medical Hypotheses, 7(2), February 1981, p. 217-229.63. S.G. Ivanov, et al., "The Magnetotherapy of Hypertension Patients," Ter Arkh, 62(9), 1990, p. 71-74.64. R. Cadossi, "Protective Effect of Electromagnetic Field Exposure on Acute Soft Tissue Ischaemic Injury," Second World Congress for Electricity and Magnetism in Biology and Medicine, 8-13 June 1997, Bologna, Italy.65. I.E. Ganelina, et al., "Electromagnetic Radiation of Extremely High Frequencies in Complex Therapy for Severe Stenocardia," Millimetrovie Volni v Biologii I Meditcine, (4), 1994, p. 17-21.

67. V.V. Orzeshkovskii, et al., "Clinical Application of Electromagnetic Fields," in I.G. Akoevs & V.V. Tiazhelov, (eds.), Topics of Experimental and Applied Bioelectromagnetics. A Collection of Research Papers, Puschcino, USSR, USSR Academy of Sciences, Biological Sciences Research Center, 1983, p. 139-147.68. N.N. Naumcheva, "Effect of Millimeter Waves on Ischemic Heart Disease Patients," Millimetrovie Volni v Biologii I Meditcine, (3), 1994, p. 62-67.69. A.P. Dovganiuk & A.A. Minenkov, "The Use of Physical Factors in Treating Chronic Arterial Insufficiency of the Lower Limbs," Vopr Kurortol Fizioter Lech Fiz Kult, (5), 1996, p. 7-9.70. V.V. Orzheshovski, et al., "Efficacy of Decimeter-Band Waves and Magnetophore Therapy in Patients with Hypertension," Vrach Delo, (1), 1982, p. 65-67.71. L.L. Orlov, et al., "Indications for Using a New Magnetotherapeutic Method in Arterial Hypertension," Soviet Medicine, (8), 1991, p. 23-24.73. I.G. Alizade, et al., "Magnetic Treatment of Autologous Blood in the Combined Therapy of Hypertensive Patients," Vopr Kurortol Fizioter Lech Fiz Kult, (1), 1994, p. 32-33.74. E.V. Rolovlev, "Treatment of Essential Hypertension Patients an Alternating Magnetic Field Puncture," All-Union Symposium: Laser and Magnetic Therapy in Experimental and Clinical Studies, June 16-18, 1993, Obninsk, Kaluga Region, Russia, p. 221-223.76. S.G. Ivanov, et al., "Use of Magnetic Fields in the Treatment of Hypertensive Disease," Vopr Kurortol Fizioter Lech Fiz Kult, (3), 199377. S.G. Ivanov, "The Comparative Efficacy of Nondrug and Drug Methods of Treating Hypertension," Ter Arkh, 65(1), 1993, p. 44-49.80. L.L. Orlov, et al., "Effect of a Running Pulse Magnetic Field on Some Humoral Indices and Physical Capacity in Patients with Neurocirculatory Hypo- and Hypertension," Biofizika, 41(4), 1996, p. 944-948.81. T.A. Kniazeva, "The Efficacy of Low-Intensity Exposures in Hypertension," Vopr Kurortol Fizioter Lech Fiz Kult, 1, 1994, p. 8-9.82. A.G. Kakulia, "The Use of Sonic Band Magnetic Fields in Various Diseases," Vopr Kurortol Fizioter Lech Fiz Kult, 3, 1982, p. 18-21.83. S.S. Gabrielian, et al., "Use of Low-Frequency Magnetic Fields in the Treatment of Patients with Atherosclerotic Encephalopathy," Vopr Kurortol Fizioter Lech Fiz Kult, 3, 1987, p. 36-39.Journal of Back and Musculoskeletal Rehabilitationhttp://iospress.metapress.com/app/home/contribution.asp?wasp=h83ak04tvqcqxk34gt7r&referrer=parent&backto=searcharticlesresult s,1,1;

Issue: Volume 15, Numbers 2-3/2000 - Pages: 77 - 81 - Michael I. Weintraub A1, Steven P. Cole A2 Neuromagnetic treatment of pain in refractory carpal tunnel syndrome: An electrophysiological and placebo analysis (Carpal Tunnel and Elastomag products) A1 New York Medical College, Departments of Neurology and Medicine, 325 S. Highland Avenue, Briarcliff, NY 10510, USA - A2 Research Designs, Inc., Yorktown Heights, NY, USA Abstract:{\it Objective:} To evaluate the neurobiological effect of constant, subthreshold magnetic field exposure on symptomatic median nerve compression symptoms, neurophysiology and assess the role of placebo. {\it Background:} Conservative treatment of moderate and severe CTS has been variable and often results in surgical decompression at the wrist. {\it Design/methods:} Eight moderately symptomatic and intractable CTS hands constantly wore identical Elastomag wrist support wraps (unmagnetized vs. Magnetized 350 gauss) for one month intervals. Identical wraps were then switched at the second month. Baselineassessments included the neurological exam, VAS scores for burning, numbness and tingling twice a day on a 10 point ordinal scale. CMAP/SNAP was determined at baseline and monthly intervals. Clinical follow-up at end of fourth and eighth weeks was compared to baseline. {\it Results:} The mean pain scores improved in four patients (57%) which also correlated with clinical benefit. Improvement in Tinel and Phalen sign as well as sensory changes wassimilarly noted. Placebo effect was detected in one patient (13%). Electrophysiological improvement in distal latencies in 5/8 hands using magnetic treatment was noted compared to no change or worsening in all placebo cases. {\it Conclusions:} Percutaneous magnetic stimulation induced palliative pain relief, presumably via modulation of the unmyelinated C-fibers. Prior studies have suggested an influence on K+ inward rectification excitability. These observations suggest that wearing magnetized wrist wraps appears to be a novel therapeutic agent. However, the underlying neuropathology tends to be progressive.References:1. K.A. Cseuz, J.E. Thomas, E.H. Lambert, J.G. Love and P.R. Lipscomb, Long-term Results of Operations for Carpal Tunnel Syndrome, Mayo Clin Proc 41 (1966), 232-241.2. G. Omer, Median Nerve Compression at the Wrist, Hand Clin 8 (1992), 317-324.3. K. Nakagawa, Study on Clinical Effects of the Magnetic Necklace, in: TBK Magneto Medical Publication Series I, Beverly Hills (Cal), 1975, pp. 1-12.4. C.Z. Hong, J.C. Lin, L.P. Bender, J.N. Schaeffer, R.J. Mettzer and P. Causin, Magnetic Necklace: Its Therapeutic Effectiveness on Neck and Shoulder Pain, Arch Phys Med Rehab 63 (1982), 462-466.

5. C. Vallbona, C.F. Hazelwood and G. Jurida, Response of Pain to Static Magnetic Fields in Postpolio Patients: A Double- Blind Pilot Study, Arch Phys Med Rehabil 78 (1997), 1200-1203.6. D.N. Dawson, Entrapment Neuropathies of the Upper Extremities, N Eng J Med 329 (1993), 2013-2018.7. A.V. Cavopol, M.J. McLean and R.R. Holcomb, An Explanatory Mechanism for Blockade of Action Potentials in NeuralCells by External Magnetic Fields. Fifteenth Annual Meeting of the Bioelectromagnetics Society. Abstract A-1-6, 1993.8. D.O. Carpenter and S. Ayrapetyan, eds, Biological Effects of Electric and Magnetic Fields, Academic Press, San Diego,1994.9. M.J. McLean, R.R. Holcomb, A.W. Wamil, J.D. Pickett and A.V. Cavopol, Blockade of Sensory Neuron Action Potentialsby a Static Magnetic Field in the 10 mT Rage, Bioelectromag-netics 16 (1995), 20-32.10. M.I. Weintraub, Chronic Submaximal Magnetic Stimulation in Peripheral Neuropathy: Is there a Beneficial TherapeuticRelationship? Amer J Pain Management 8 (1998), 12-16.11. M.I. Weintraub, Magnetic Bio-Stimulation in Painful Diabetic Peripheral Neuropathy: A Novel Intervention. A Randomized,Double-Placebo Crossover Study, Amer J Pain Management 9 (1999), 8-17.12. E.A. Collacott, J.T. Zimmerman, D.W. White and J.P. Rindone, Bipolar Permanent Magnets for the Treatment of ChronicLow Back Pain, JAMA 283 (2000), 1322-1325.13. M. McLean, S. Engstrom and R. Holcomb, Static Magnetic Fields for the Treatment of Pain, Epilepsy and Behavior 2 (2001),S74-S80.Dental Research Studieshttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESThis placebo-controlled study examined the effects of micromagnets in the treatment of periodontal disease. Micromagnetswere attached to the skin over areas of inflammation for a period ranging from 1 to 8 days, with the number of magnets used atonce varying from 1 to 6. The course of treatment lasted as long as 4 weeks. Results indicated that patients receiving themicromagnet therapy experienced earlier and more trouble-free recoveries following oral surgery, as well as less pain relativeto controls.99

This controlled study examined the effects of adjunctive Diapulse electromagnetic therapy on oral surgery recovery. Patientsreceived the therapy once per day beginning between 3 to 5 days prior to oral surgery. Therapy was maintained until the pointof hospital release. Results found the therapy produced significant healing relative to controls, who received conventional treatment only.100This study found that patients suffering from various oral diseases experienced more rapid healing when treated with both conventional therapies and 30 minutes per day of pulsed electromagnetic fields (5 mT, 30 Hz), as opposed to conventional therapies alone.101References99. V.E. Kriokshina, et al., "Use of Micromagnets in Stomatology," Magnitologiia, (1), 1991, p. 17-20.100. L.C. Rhodes, "The Adjunctive Utilization of Diapulse Therapy (Pulsed High Peak Power Electromagnetic Energy) in Accelerating Tissue Healing in Oral Surgery," Q National Dental Association, 40(1), 1981, p. 4-11.101. V. Hillier-Kolarov & N. Pekaric-Nadj, "PEMF Therapy as an Additional Therapy for Oral Diseases," European Bioelectromagnetics Association, 1st Congress, 23-25 January 1992, Brussels, Belgium.Depression Research StudiesDouble-Blind, Magnet Therapy Eases Severe Depressionhttp://www.sciencedaily.com/releases/1999/04/990415064738.htmThe effectiveness of repetitive transcranial magnetic stimulation (rTMS), a refinement of TMS, was tested on 67 patients in a doubleblind study -- in which neither the patients nor the researchers are told who is receiving the treatment and who is receiving the sham.At the end of two weeks, half the patients in the rTMS group showed a 50 percent improvement in their depression ratings. Only onequarter of those in the sham-treated group showed the same improvement. Moreover, half the patients receiving the treatment had no need for further treatment with ECT, while all those receiving the sham treatment required it. "Our findings are very exciting, since term," explained Dr. Ehud Klein of the Faculty of Medicine at the Technion and head of the Department of Psychiatry at Rambam Medical Center in Haifa. "The treatment holds the promise of eliminating the need for ECT therapy in many cases." "It's a landmark work," said Dr. Mark George, Professor of Psychiatry at Medical University of South Carolina, about the Technion research. His view was seconded by Dr. Robert Berman, Assistant Professor of Psychiatry at Yale School of Medicine, who noted that "Dr. Klein's group, which has been at the forefront of developing TMS, now corroborates earlier reports on the effectiveness of TMS with the first largescaleinvestigation."

Other Depression Research Studieshttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED CIENTIFIC STUDIESFollowing are descriptions of 6 recent studies, many of which are double blind studies, published in peer-reviewed scientific journals, on the impact of treatment with magnetic fields on a variety of conditions: This review article examined the literature concerning the use of transcranial magnetic stimulation in the treatment of depression. Results showed the high-frequency, repetitive transcranial magnetic stimulation treatment to be an effective, side-effect free therapy for depression that may hold promise for treating related psychiatric disorders as well.103 Noting that there is good reason to believe the pineal gland is a magnetosensitive system and that application of magnetic fields inexperimental animals has a similar effect to that of acute exposure to light with respect to melatonin secretion, the authors propose that magnetic treatment could be a beneficial new therapy for winter depression in humans.104 This review article notes that transcranial magnetic stimulation has been shown to elicit antidepressant effects, electrically stimulating deep regions of the brain.105 In this theoretical paper, the author argues that deep, low-rate transcranial magnetic stimulation can produce therapeutic effects equivalent to those of electroconvulsive therapy but without the dangerous side effects106 This study examined the effects of millimeter wave (MW) therapy as a supplemental treatment in patients suffering from various types of depression. MW therapy involved the use of a "Yav'-1" apparatus (5.6 mm wavelength, 53 GHz), and consisted of up to 60 minutes of exposure per day, 2 to 3 times per week, for a total of as many as 15 exposures. Results showed that combined MW/conventional treatment produced a complete recovery in over 50 percent of cases studied a significant improvement in 41 percent, and some improvement in 8 percent. Recovery rates among controls (conventional treatment only) were 4, 48, and 41 percent, respectively.108 Results of this study led researchers to conclude that patients suffering from major depression experienced a significant reduction of depressive symptoms following treatment with transcranial magnetic stimulation coupled with standard medication relative to patients taking the medicine. This was true after just three TMS treatments.109103. M.T. Kirkcaldie, et al., Transcranial Magnetic Stimulation as Therapy for Depression and Other Disorders," Aust N Z J Psychiatry, 31(2), April 1997, p. 264-272.104. R. Sandyk, et al., "Magnetic Fields and Seasonality of Affective Illness: Implications for Therapy," International Journal of Neurosci, 58(3-4), June 1991, p. 261-267.

105. C. Haag, et al., "Transcranial Magnetic Stimulation. A Diagnostic Means from Neurology as Therapy in Psychiatry?" Nervenarzt, 68(3), March 1997, p. 274-278.106. T. Zyss, "Will Electroconvulsive Therapy Induce Seizures: Magnetic Brain Stimulation as Hypothesis of a New Psychiatric Therapy," Psychiatry Pol, 26(6), November-December 1992, p. 531-541.107. G.V. Morozov, et al., "Extremely-High Frequency Electromagnetic Radiation in the Treatment of Neurotic Depression in Women," Millimeter Waves in Medicine & Biology. Digest of Papers of the 10th Russian Symposium with International Participation, April 24-26, 1995, Moscow, Russia, p. 49-51.108. G.V. Morozov, et al., "Treatment of Neurotic Depression with a Help of Extremely High Frequency Electromagnetic Radiation," Zh Nevropatol Psikhiatr Im S S Korsakova, 96(6), 1996, p. 28-31.109. A. Conca, et al., "Transcranial Magnetic Stimulation: A Novel Anti-depressive Strategy?" Neuropsychobiology, 34(4), 1996, p. 204-207.Diabetes Research StudiesPEER-REVIEWED SCIENTIFIC STUDIEShttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESIn this study, 320 diabetics received impulsed magnetic field treatment while 100 diabetics (controls) received conservative therapy alone. Results showed beneficial effects with respect to vascular complications in 74 percent of the patients receiving magnetotherapy combined with conservative methods, compared to a 28-percent effectiveness rate among controls.111 This study involving 72 diabetics with purulent wounds found that magnetic fields aided healing significantly.113 References111. I.B. Kirillovm, et al., "Magentotherapy in the Comprehensive Treatment of Vascular Complications of Diabetes Mellitus," Klin Med, 74(5), 1996, p. 39-41.113. R.A. Kuliev & R.F. Babaev, "A Magnetic Field in the Combined Treatment of Suppurative Wounds in Diabetes Mellitus," Vestn Khir Im I I Grek, 148(1), January 1992, p. 33-36.Ear Research Study (Otitis Externa)http://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESThis study examined the effects synchronizing pulse waves in the impaired area when treating patients suffering from acute diffuse otitis externa with low-level magnetic fields in combination with conventional therapies. Patients were divided into three groups. The first received ultrahigh-frequency or very-high-frequency electromagnetic waves. The second received 15-minute daily

exposures to 50-Hz alternating or pulsating 20-mT magnetic fields. The third group of patients were treated switching on the same magnetic fields only during propagation of the pulse wave through the ear vessels. Results showed a 100 percent recovery rate in patients across all three groups, with recovery taking the least amount of time among those in group 3.239References239. V.V. Sunstov, "Treatment of Acute Diffuse Otitis Externa Low-Frequency Magnetic Fields," Vestn Otorinolaringol, 6, 1991, p. 35-38.Effects of Nikken Magnetic Insoles on Diabetic NeuropathyThird Phase of the Weintraub STUDY Summary:http://health.discovery.com/centers/althealth/diabetic.htmlRadio interview with Dr. Michael Weintraub is on audio tape. Through Team Tools: 1-800-667-0198• The Longitudinal Study was carried out with 264 patients with Diabetic Neuropathy took part in a 4 month study in 48 centers in 27 states according to strict randomized double-blind / placebo design• The lead researcher was internationally known Michael Weintraub, M.D., FACP• The results of this study [which have been tabulated and reviewed by NIH], will be reported as the Keynote Address for the annual meeting of the American College of Neurology as well as will appear shortly in the upcoming issues of JAMA (Journal of the American Medical Association).RESULTS:- 90% OF THE PATIENTS REPORTED A POSITIVE OUTCOME, I.E. REDUCTION IN DIABETIC NEUROPATHY SYMPTOMS (numbness, tingling, burning)- REPORTED INCREASE IN MICROCIRCULATION (foot warmth)- REPORTED INCREASE IN BALANCE and COORDINATIONCONCLUSIONS:All Magnetic Insoles are NOT created equalNikken's design was THE ONLY insole that provided consistent resultsUse of these insoles will slow the progression of Diabetic Neuropathy and conditions related to compromised Microcirculation (Diabetic Ulcers, Gangrene)Reduction in foot amputations (approximately 54,000 annually)Endometriosis Research Studyhttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESThis study found that a combined treatment consisting of magnetic-infrared-laser therapy (10-15 min/day ever other day over a period of 10-14 exposures,

then repeated in 2-3 months) and conventional drug therapy proved highly effective in women suffering from endometriosis.119References 119. M. Damirov, et al., "Magnetic-Infared-Laser Therapeutic Apparatus (MILTA) in Treatment of Patients with Endometriosis,"Vrach, 12, 1994, p. 17-19.----------------------------------------------------------------------------------------------------------Dr. William Pawluk, M.D., MSC. President of Advanced Magnetic Research Institute. Assistant Professor at John Hopkins University. Co-author of Magnetic Therapy in Eastern Europe said 45% of women have endometriosis which is one of the leading causes of infertility. Magnets around the pelvic area makes a difference in 25- 35% fertility rate for women who have not conceived for years.Epilepsy Research Studieshttp://www.pslgroup.com/dg/16596e.htmBOCA RATON, FL -- February 17, 2000 -- Jacobson Resonance Enterprises, Inc. reported the results of a double blind, pilot clinical study in epilepsy conducted at the University of Oklahoma Health Sciences Center by principal investigator Kalarickal Oommen, M.D., director of epilepsy research and nationally recognized authority in the treatment and research of epilepsy seizures. The data indicated that treatment with the Jacobson Resonator, utilizing low-intensity and low-frequency magnetic fields, decreased seizure frequency in some patients with intractable partial complex epilepsy significantly and that this modality may be a useful adjunctive treatment in these patients and others. Intractable partial complex epilepsy patients were enrolled in a pilot medical study in a non-randomized and double blind fashion. In the first phase of seven weeks, each patient received either magnetic treatment or no treatment for 40 minutes per treatment per week.In the second phase of seven weeks, the order was reversed for patients receiving no treatment or magnetic field treatment. It was found that 66 percent of the patients had a mean decrease in seizure frequency of 33 percent plus during the study.Dr. Kalarickal Oommen stated, "The results are very encouraging when you compare it to the way anti-epileptic drugs (AEDs) are approved by the FDA. The percentages for some of the recently marketed AEDs and the Vagus Nerve Stimulator were in the 17-25 percent range or under. I believe this is great news, particularly when you consider that patients were only treated once a week and non-invasively."Dr. Jerry Jacobson, Chairman and CEO, stated, "The follow-up study will be double blinded and contain a greater population of patients who will be treated three times per week instead of only once a week. We are hopeful that the

seizure reduction level will thus rise to 50 percent. We are moving quickly with I.R.B. approval for our next phase of the clinical trial and hope to request to the FDA 'expedited review' for approval next year.Epilepsy Research Study http://infoventures.com/emf/currlit/bu11781.htmlThe effects of DC magnetic fields on brains of epilepsy patients were investigated. Application of 1- to 2-mT magnetic fields induced significantly higher levels of epileptiform activity in 6 of 8 patients with drug resistant meso-temporal lobe epilepsy. Removal of the fields appeared to cause epileptiform discharges in some instances, suggesting that the change in field may be more important than application of a magnetic field. The reason for enhanced sensitivity of epilepsy patients to magnetic fields is not known. The authors speculate that it could be related to the existence of biomineralized ferrimagnetic magnetite, which has been found in brain tissues of epileptic and nonepileptic subjects, or it could reflect a direct effect of the field on some aspect of central nervous system activity.Epilepsy Research Studieshttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESThis article reports on the cases of three patients with partial seizures who received treatment with external artificial magnetic fields of low intensity. Such treatment led to a significant attenuation of seizure frequency over a 10-14-month period.121 Experimental results indicated that the administration of modulated electromagnetic fields of 2-30 Hz suppressed epilepsy in rats.122This review article cites one study in particular in which results showed that pretreatment with 30 minutes of exposure to a 75-mT pole strength, DC-powered magnetic field significantly prevented experimentally induced seizures in mice.123 This double-blind, placebo-controlled study examined the effects of 2-hour exposure to weak magnetic fields (0.2-0.7 G, irregularly oscillating 0.026-0.067 Hz) produced 3 pairs of orthogonal Helmholtz coils on pain perception in healthy subjects. Results showed that magnetic treatment significantly reduced the perception of pain.124 This article reports on the case of a severe epileptic who experienced a significant lessening of behavior disturbances and seizure frequency following treatment with low-frequency, external artificial magnetic fields.125 Low-frequency, external artificial magnetic field treatment was shown to significantly reduce seizures in four adult epileptic cases.126References121. P.A. Anninos, et al., "Magnetic Stimulation in the Treatment of Partial Seizures," International Journal of Neurosci, 60(3-4), October 1991, p. 141-171.

122. G.D. Antimonii & R.A. Salamov, "Action of a Modulated Electromagnetic Field on Experimentally Induced Epileptiform Brain Activity in Rats," Biull Eksp Biol Med, 89(2), February 1980, p. 145-148.123. 123. M.J. McLean, et al., "Therapeutic Efficacy of a Static Magnetic Device in Three Animal Seizure Models: Summary of Experience," Second World Congress for Electricity and Magnetism in Biology and Medicine, 8-13 June 1997, Bologna, Italy.124. 124. F. Sartucci, et al., "Human Exposure to Oscillating Magnetic Fields Produces Changes in Pain Perception and Pain- Related Somatosensory Evoked Potentials," Second World Congress for Electricity and Magnetism in Biology and Medicine, 8- 13 June 1997, Bologna, Italy.125. 125. R. Sandyk & P.A. Anninos, "Attenuation of Epilepsy with Application of External Magnetic Fields: A Case Report," International Journal of Neurosci, 66(1-2), September 1992, p. 75-85.126. 126. R. Sandyk & P.A. Anninos, "Magnetic Fields Alter the Circadian Periodicity of Seizures," International Journal of Neurosci, 63(3-4), April 1992, p. 265-274.Eyelid Infection Research Studyhttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESResults of this study indicated that the use of an alternating magnetic field in conjunction with a magnetic ointment containing reduced iron powder had beneficial effects in patients with chronic blepharitis.12References12. V.A. Machekhin, et al., "A New Method for Treating Chronic Blepharitis Using Magnetic Compounds and an Alternating Magnetic Field," Vestn Oftalmol, 109(4), July-September 1993, p. 16-18.Glaucoma Research Studyhttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESIn this study, patients with primary open-angle glaucoma with compensated intraocular pressure were administered magnetotherapy using an ATOS device with 33-mT magnetic field induction. The procedure was administered to a patient in a sitting posture with a magnetic inductor held before the eye. Sessions lasted 10 minutes and each course included 10 sessions. Following 4-5 months of therapy, results showed improved vision acuity 0.16 diopters, on an average of 29 out of 30 eyes with vision acuity below 1.0. 149References149. Bisvas, et al., "Possibilities of Magnetotherapy in Stabilization of Visual Function in Patients with Glaucoma," Vestn Oftalmol, 112(1), Jauary-March 1996, p. 6-8.

Magnet Therapy & Fibromyalgia Pain:New Research from the University Of VirginiaMagnet Therapy Shows Some Potential For Pain Relief - March, 2001Results are inconclusive, but a study of magnet therapy found the controversial treatment reduced fibromyalgia pain intensity enough in one group of study participants to be "clinically meaningful," the researchers said.University of Virginia (UVa) researchers published the results of one of the first clinical research studies conducted on magnet therapy for pain in the February 23, 2001, issue of the Journal of Alternative and Complementary Medicine.Three measures of pain were used: functional status reported by study participants on a standardized fibromyalgia questionnaire used across the U.S., number of tender points on the body, and pain intensity ratings. Data were compiled for 94 fibromyalgia patients randomly divided into four groups. One control group received sham pads containing magnets that had been demagnetized through heat processing. The second control group received only their usual treatment for fibromyalgia. Two other groups received active magnetic pads: one group used Pad A, which provided whole-body exposure to a low, uniformly static magnetic field of negative polarity. The other used Pad B, which exposed subjects to a low static magnetic field that varied spatially and in polarity. The subjects were treated and tracked for six months."When we compared the groups, we did not find significant statistical differences in most of the outcome measures," said Ann Gill Taylor, RN, EdD, co-investigator for the study, professor of nursing, and director and principal investigator of the Center for Study of Complementary and Alternative Therapies at the University of Virginia. "However, we did find a statistically significant difference in pain intensity reduction for one of the active magnet pad groups. The two groups that slept on pads with active magnets generallyshowed the greatest improvements in outcome scores of pain intensity level, number of tender points on the body and functional status after six months."Pad A group exhibited a consistent improvement across all four outcome measures at three and six months. Pad B group showed an improvement in all outcomes at three months, and these improved scores were maintained at six months. The sham pad group and the group receiving only usual care did not exhibit the same improvements. The magnetic fields of the mattresses were tested thoroughly to quantify how much exposure, or dosage, study participants were receiving, the researchers said."Finding any positive results in the groups using the magnets was surprising, given how little we know about how magnets work to reduce pain," said the study's principal investigator Dr. Alan P. Alfano, assistant professor of physical medicine and rehabilitation and medical director of the UVa HealthSouth Rehabilitation Hospital. "The results tell us maybe this therapy works, and that

maybe more research is justified. You can't draw final conclusions from only one study.""To our knowledge, no other studies on magnet therapy have been done in as rigorous a clinical setting as UVa, and this study was the largest conducted so far," Taylor said. "Nevertheless, larger studies are needed to find clear answers about magnets' safety and efficacy in treating pain.""Fibromyalgia is a common rheumatological condition for which there is no generally effective treatment," Alfano explained. "People who have fibromyalgia try everything and magnetic mattress pads are one of the most popular complementary products they try. We did this study because we hoped to provide some useful information for them."In the past decade, people in this country have been using magnets for everything from tennis elbow to carpal tunnel syndrome. They want to do something for their pain that doesn't involve medication or injections, and magnets seem relatively benign. But people don't know how to evaluate magnetic products when considering what to buy," Alfano continued. "There are no standards for magnets yet. So researchers need to find out what dosage, field strength, and period of exposure is proper, what side effects may occur and what conditions benefit most."Two other basic science laboratory studies currently underway at Uva are investigating the effects of pulsed and static magnetic fields on neural processes and functions and the effects of magnetic fields on microvascular capillary blood flow.The study was conducted with partial support from a grant from the U.S. National Institutes of Health Center for Complementary and Alternative Medicine.To see more of the NewsRx.com, or to subscribe, go to http://www.newsrx.comMagnetic Mattress Pad Use in Patients with Fibromyalgia:A Randomized Double-blind Pilot Study.Agatha P. Colbert, M.D. Clinical Assistant Professor of Physical Medicine and Rehabilitation Tufts University School of Medicine, Boston, MA 02111Marko S Markov, Ph.D.Department of OrthopedicsMount Sinai School of Medicine, New YorkMandira Banerji, M.A.Research Assistant, Litterst & Associates, Newton, MAArthur A Pilla, Ph.D.Department of Orthopedics, Mount Sinai School of Medicine, New YorkDepartment of Biomedical Engineering, Columbia University, New YorkAcknowledgements:

Partial support for the project was provided by Magnetherapy, Inc. and by the Horace W. Goldsmith Foundation.The authors wish to honor the late Bill Roper whose encouragement and support made this project possible Please request reprints from the corresponding author:Agatha P.Colbert, M.D.25 Grant Street, Suite 4,Waltham, MA 02453.E-mail: apcolbert@mediaone.netJournal of Back and Musculoskeletal Rehabilitation 13(1999) 19-31ISSN 1053-8127/$8.00 Copyright 1999, IOS Press. All rights reserved.ABSTRACTMagnetic Mattress Pad Use in Patients with Fibromyalgia: a Randomized Double-blind Pilot Study.Objective: To determine if the chronic pain and sleep disturbances experienced by patients with fibromyalgia can be improved by sleeping on a magnetic mattress pad.Design: A double-blind randomized controlled trial.Setting: Patients’ homes and the private practice office of the principal investigator.Patients: Thirty-five female subjects diagnosed with fibromyalgia syndrome were recruited. Thirty met inclusion/exclusion criteria and entered the study. Twenty-five completed it. One was lost to follow-up. Three were withdrawn for protocol violations and one because of an intercurrent hospitalization.Intervention: Sleeping on an experimental (magnetized at a magnet surface field strength of 1100 ± 50 Gauss and delivering 200-600 Gauss to the skin surface or a sham (non-magnetized) mattress pad over a 16 weekperiod.Main Outcome Measures: Visual Analog Scales (VAS) for global wellbeing, pain, sleep, fatigue and tiredness on awakening; Total Myalgic Score; Pain Distribution Drawings; and a modified Fibromyalgia Impact Questionnaire.Results: Subjects sleeping on the experimental mattress pad experienced a significant decrease in pain (p <.05), fatigue (p<.006), total myalgic score (p <.03), and pain distribution drawing (p < .02). Additionally, these subjects showed significant improvement in reported sleep (p <.01) and physical functioning as evidenced from the modified Fibromyalgia Impact Questionnaire (p < .04). Subjects sleeping on the sham mattress pad experienced no significant change in these same outcome measures. Subjects in both the control and experimental groups showed improvement in tiredness on wakening, demonstrating a placebo effect in this parameter. Neither group showed any effect on global wellbeing.

Conclusions: Sleeping on a magnetic mattress pad, with a magnet surface field strength of 1100+-50 Gauss, delivering 200-600 Gauss at the skin surface provides statistically significant and clinically relevant pain relief and sleep improvement in subjects with fibromyalgia. No adverse reactions were noted during the16-week trial period.IntroductionFibromyalgia (FM), characterized by chronic, widespread, musculoskeletal pain and stiffness, disturbed sleep and fatigue, is a common, well-recognized clinical syndrome. Prevalence rates for women are estimated at 3.4%, and for the general population, 2% 1 with an even higher rate among military personnel, ranking second in the list of most frequently self-reported symptoms among Gulf War veterans (19.2 %) 2. The etiology and pathophysiology of this disorder remains uncertain. Current management strategies, both pharmaceutical and non-pharmaceutical, provide limited symptomatic relief. Medications such as the tricyclic antidepressants, benzodiazepines, anti-inflammatory agents, and other CNS active medications have produced meaningful improvement 30% to 50 % of patients3, with unwanted side effects experienced by up to 98%4. Non-medicinal treatments including: aerobic exercise and stress management5, electroacupuncture6, hypnotherapy7, electromyography-biofeedback8, and cognitive behavioral therapy9 provide significant benefit, and have minimal adverse effects, compared with medications, but require active compliance on the part of the patients for lasting relief.Low frequency pulsing electromagnetic fields (EMF), first approved by the Food and Drug Administration (FDA) in 1979, are commonly used to treat recalcitrant bone fractures and soft tissue injuries10,11. Therapeutic permanent magnets are gaining worldwide popularity for self-administered pain control. The standard physical unit of measure for magnetic field strength is Tesla (T). One Tesla is equal to 10,000 Gauss (G). For comparison, the earth’s magnetic field is approximately 0.5 G, while a standard MRI instrument utilizes magnetic fields in the range of 1.5 -2.5 T (15,000 - 25,000 G). Gauss will be used to characterize the magnetic field level employed in this study. Therapeutic devices utilizing permanent magnets are not yet regulated in the United States.A Medline search of the relevant literature in English revealed only three reports of controlled trials in which the therapeutic efficacy of permanent magnets was assessed. A 1982 study of a magnetic necklace for neck and shoulder pain found no difference in therapeutic benefit between groups wearing the sham or the magnetized necklaces12. A more recent double-blind pilot study documented approximately 70% pain reduction in patients with post-polio syndrome, after permanent magnet (surface field strength of 300-500 G) application to painful trigger points for a 45-minute period13. Neuropathic

pain from diabetic neuropathy is also reportedly diminished as a result of wearing magnetic insoles14.A double-blind study at San-Ikukai Hospital in Japan15 demonstrated effective pain control in over 70% of 375 individuals who used static magnetic mattress pads for a variety of musculoskeletal pain complaints. The permanent magnets embedded in the mattress pads had a surface field strength of 750-950 G. In Japan, these devices are regulated for therapeutic efficacy at a minimum surface field strength of 500 G. No adverse effects related to the use of static magnets were reported in any of these studies.In general, permanent magnets used for therapeutic purposes are of two structural types: flexible (made of plastilloy) or hard (ceramic or metal based). Manufacturers characterize their magnetic products by the term "gauss rating", which describes the magnetization energy at the core of the magnet. This designation however, does not specify the therapeutic importance or dosimetry of a magnet as it gives no information about the magnetic field at the magnet’s surface or the amount of magnetic energy delivered to the target tissue. Themagnetic field strength (flux density) of a permanent magnet is measured with a magnetometer or Gauss meter, usually with a Hall effect probe. The flux density decreases exponentially with distance from the magnet’s surface. The actual dosage of magnetic energy delivered to the target tissue(s) depends upon the relative size of the magnet and target and the distance the area to be treated is from the magnet. Since the magnetic field penetrates all tissues in exactly the same manner as in air dosimetry can be estimated, based on magnetic fieldmeasurements in air. The magnetic field strength of mattress pads containing magnets is a function of the magnetization energy, the size, the volume and the shape of a particular magnet, as well as the configuration in which the magnets are placed in a given mattress pad. In addition, when an individual is lying on a foam mattress pad in which ceramic magnets are embedded, other factors, such as the individual’s weight, the compressibility of the mattress foam, or whether the patient is in a side-lying, prone or supine position influence the magnetic dosage delivered to specific areas of the body. All layers of human tissue are equally penetrated by a magnetic field. The only factors that affect the actual magnetic field "seen" by the tissue are its distance from the surface of the magnet and its orientation with respect to that surface.Although, to date, the clinical literature on therapy using permanent magnets is sparse, there is compelling evidence that both electromagnetic and static magnetic fields have physiologically relevant biological effects on the human organism16-25.In light of this background information on therapeutic magnets, and the fact that pharmaceutical management strategies for treating patients with fibromyalgia have limited success and a high incidence of associated adverse effects, this

study was designed to investigate the potential benefits of a magnetic mattress pad for reducing pain and improving sleep in this patient population.SUBJECTS AND METHODSSubjectsThirty-five female subjects with fibromyalgia were recruited from three sources: the principal investigator’s clinical practice, a referring physical therapy group and a local fibromyalgia support group. Thirty subjects metthe inclusion/exclusion criteria and were accepted for participation in the study. Five subjects did not complete the study: one withdrew on her own, one was withdrawn because of an intercurrent psychiatric hospitalization, three others were withdrawn because of protocol violations. (See the Results section for more detail). The average age of the 25 subjects who completed the study was 49.7 years, ranging from 25 to 78 years. The average weight was 166 lbs., ranging from 115 to 216 lbs. Chronic diffuse pain symptoms were present for aminimum of two years in all subjects. Ten subjects were married; 5 were single; 7 divorced; and 3 were unmarried, but living with a partner. Sixteen were employed outside the home. Four were receiving medical disability benefits. See Table 1.Inclusion/exclusion criteriaSubjects were enrolled in the study if they met the American College of Rheumatology’s diagnostic criteria for fibromyalgia syndrome26. Patients had to have a history of pain for greater than three months, present on both the right and left sides of the body, and above and below the waist. Subjects had to agree to start no new pain medications, or additional pain management modalities during the 16-week trial period. Study participants were allowed to continue taking current medications or maintain therapies such as physical therapy, acupuncture, chiropractic or myofascial release, if they had been taking the medications or engaged in the specific therapeutic modality for a minimum of four previous weeks. The medications and therapeutic modalities being used byboth patient groups are given in Tables 2 and 3 respectively. There was no significant difference in the number of subjects in both groups who maintained other therapies (p = .40) or continued to use prescribed medications (p=.087) during this study. It was anticipated that, if the magnetic mattress pad was to be effective, a significant improvement above and beyond that derived from a maintenance pain control program would be evident. Two of the recruited candidates excluded themselves from the study because they had previously experienced a temporary worsening of symptoms while wearing 800 G neodymium magnets on acupuncture points. The other three recruits were excluded because they anticipated prolonged travel or the possibility of starting a new pain medication within the time period of the therapeutic trial. The study was approved by the Tufts University School of Medicine Investigational

Review Board through the Department of Physical Medicine and Rehabilitation. All subjects gave written informed consent.Research designThis was a randomized double-blind pilot study, performed at the patient’s home and at the principal investigator’s private practice office. Subjects were randomly assigned to either the experimental or control group. The mattress pads were shipped directly to the subject’s home. The code was kept by the manufacturer until all data was entered into the computer system, at which time it was sent to the biostatistician who had no contact with the subjects. Neither the principal investigator nor her research assistant saw any of the mattress pads, and both remained blinded observers throughout the clinical assessments and data analysis phases. There was no contact between the code-keeper (manufacturer), the patient, anyone who had contact with the patient or the biostatistician, during the course of this study.At baseline all subjects underwent an initial clinical examination by the principal investigator to confirm the diagnosis of fibromyalgia according to the criteria of the American College of Rheumatology26. Subjects were also seen for two follow-up visits: after two weeks of mattress use and again for a final evaluation at the end of the trial period. All evaluations were performed by the principal investigator to avoid problems with interrater reliability. Each subject mailed in completed weekly visual analog scales for global wellbeing, pain, sleep disturbance, fatigue and tiredness on wakening. Subjects were seen for a final visit after 16 weeks of sleeping on the mattress pad. The research assistant and principal investigator were available by telephone at all times during the study period and the majority of subjects were in weekly communication. Subjects were advised not to discuss issues related to the study if they happened to meet another participant in the study.Therapeutic InterventionSubjects were asked to sleep nightly on either a magnetized mattress pad (experimental) or on a non-magnetized pad (sham) for a 16 week period. Subjects were told to use the mattress pad at night only and not to rest on it during the day. There were no visible or textural differences between the experimental and the sham mattress pads. Both the experimental and sham mattress pads were provided by Magnetherapy, Inc*. Each pad (experimentaland sham) contained 270 domino shaped ceramic pieces, measuring 2.0 x 4.5 x 1 cm. The ceramic pieces were placed 4 cm apart and arranged in a pattern of 15 rows across and 18 rows down. All ceramic pieces were encased in the bottom layer of two layers of hospital grade foam, which were glued together. The entire pad was covered by a quilted cotton case. The total thickness of the mattress pad was 4 cm. The ceramic pieces in the mattress pads of the experimental group were magnetized with a surface field strength of 1100 ± 50

G. With this surface field strength and the positioning of magnets in the pad, it is estimated that between 200- 600 G is delivered to the skin surface at various anatomical sites. This magnetic field level is well within that reported to achieve clinically meaningful therapeutic effects13-15. Magnets were placed such that the field direction facing the body repelled a north seeking compass needle. The sham ceramic pieces were identical in every way to those in the experimental magnets, but were not magnetized. All mattress pads were shipped directly by the manufacturer to each subject’s home. Subjects were asked not to try to determine whether they had the experimental or sham pad. They were instructed to place the pad on their bed according to our directions, as soon as it was delivered. When placed in its proper position, the thickest foam layer of the pad faced upwards, making it difficult to detect magnetization with lightweight items such as paperclips.Outcome measures.The primary outcome measures were related to pain and sleep. Eight variables were studied: five Visual Analog Scales (VAS) i.e., global well-being, pain, sleep disturbance, fatigue and tiredness on wakening; Total Myalgic Score; a Body Pain Distribution Drawing; and a physical functioning score derived from the Fibromyalgia Impact Questionnaire (FIQ) 27.Visual Analog Scales (VAS)Subjects were requested to complete five VAS for global well-being, pain, sleep, fatigue and tiredness on wakening, on a weekly basis, during the 16-week study period. Visual Analog Scales are frequently used to assess these parameters in clinical trials of patients who have fibromyalgia 4,7,9,28,29. Each VAS consisted of a 10 cm. horizontal line anchored at both ends with "0" = no symptoms and "10" = worst possible symptoms. Subjects were asked to place a mark at the point on the scale, which represented their symptom level that day.In an attempt to adjust for the wide fluctuation in day to day symptoms experienced by patients with fibromyalgia, subjects were instructed to complete the VAS on Wednsedays at approximately 10 a.m.. They were specifically requested not to complete the VAS on the weekend. The completed VAS was mailed weekly, in a self-addressed stamped envelope, to the principal investigator’s office. Total Myalgic Score.The American College of Rheumatology requires that pain be reported by the patient in at least 11 of 18 tender points, when the examiner uses 4 kg. of digital pressure (the point at which the thumbnail begins to blanch)26 for a confirmed diagnosis of fibromyalgia. A baseline tender point evaluation, by palpation, was performed on the 18 predesignated anatomic regions by the principal investigator. This examination was done in accordance with the general procedures recommended for the standardized Manual Tender Point Survey 30

and scored on a three point scale. The intensity of tender point pain was scored as "2" for intense pain, "1" for moderate pain and "0" for no pain at these points. The total possible myalgic score was 36 if all the tested tender points were described as "intensely painful". Total myalgic scores were obtained by the principal investigator at the beginning and end of the trial period.Body Pain Drawing.On a body drawing with anterior, posterior and lateral views, subjects were instructed to color, with either red (severe pain) or green (moderate pain), all painful areas. No coloring meant no pain. These drawings were quantified by superimposing a template of 316 contiguous circles, and counting the number of colored circles for a total score. The template was developed by the research assistant and principal investigator. Red circles were scored as "2" and green circles as "1". The baseline drawing score was compared to the endpoint drawing score. The worst possible score, i.e., if every circle has red coloration, is 632. To establish interrater reliability, subsets of data were scored independently by the principal investigator and research assistant. Interraterreliability was computed at r =.72.Physical Functioning.The FIQ27 was developed and validated to assess current health status of women with FM. Item 1, a 10 part question, was used in this study to assess physical functioning in tasks of daily living. The best possible score for this item is 0, meaning that subjects are always able to do the 10 specified tasks of daily living. The worst possible score is 30, meaning they are never able to perform any of the tasks. Subjects were asked to complete the modified FIQ at the beginning and end of the trial period.Daily DiaryIn addition to completing their weekly VAS, subjects were requested to keep a daily diary in which to document any unusual or adverse reactions. Exact number of hours of sleep or hours spent on the mattress pad was not documented.Statistical analysisAll primary outcome measures were compared at the start of the study and at end of the 16th week for all subjects in the treated and sham groups. All outcome data were analyzed using a paired Student’s t test. The analysis of variance F test confirmed there was no significant difference in the variances for all comparisons. The Kolgomorov-Smirnov test confirmed all data sets were normally distributed. Significance was accepted for P= 0.05.RESULTSThirty female subjects met the inclusion/exclusion criteria and were enrolled in the study, which began in March 1997 and was completed in December 1997.

Five subjects did not complete the study. One from the sham group was lost to follow-up; a second also from the control group had an interim psychiatrichospitalization. Three others were withdrawn because of protocol violations. One subject from the experimental group added a new medication for pain control; another from the experimental group was discovered to have.0 been taking morphine from the onset; one subject from the control group was found to be enrolled in an active pain management program. The final number of test subjects who completed the protocol and slept on the mattress pad for 16 weeks was 25; 13 in the experimental and 12 in the control group. Table 1 shows thedemographics of the study participants. There was no significant difference in age, sex, employment, marital status, or months since onset of symptoms, between the experimental and control groups. The only significant variable was weight; the sham subjects were heavier than the real treatment subjects (p=.005). As will be seen, this had no effect on the outcome since the magnetic field level would have been within the 200-600 G range for the sham group had they been treated with active magnets.The means of all outcome data for the control and experimental groups were compared at the start (baseline) and end of treatment at week 16 (endpoint) using the paired Student’s t test. The baseline and endpoint means and standard errors of these data are summarized in Table 4 and presented in Figures 1-4 for all VAS measures except for global wellbeing since there was no significant difference in this clinical outcome for either group at any time point (see Table 4). With the exception of wellbeing in which there was a significant differencebetween the two groups at the start of the study, there was no significant difference between the mean values at baseline for the experimental and control groups. In order to assess the time course of response to treatment with static magnets, outcome data for pain, sleep, tiredness and fatigue were compared at monthly intervals by averaging the weekly means for the experimental and sham groups for each four-week period in the study. These comparisons are shown in figures 5-8. As shown in figure 5, by the 4th week subjects in the experimental group demonstrated a significant reduction in pain (p<.05) and this continued to decrease through week 12, with no significant further improvement by week 16. In contrast, there was no significant change in pain for the control group over the entire 16-week period. Figure 6 indicates a significant sleep improvement (p <.03) in the experimental group by week 12, with still further improvement at week 16 (p <.01). No significant sleep improvement was observed throughout the 16-week study period in the control group. Figure 7 shows a significant improvement in fatigue in the experimentalgroup by week 8, with no further improvement by week 16. The control group showed no significant improvement in fatigue throughout the study period. Tiredness upon awakening improved significantly in both control and

experimental groups by week 12, demonstrating a placebo effect of the magnetic field on this outcome parameter. Tiredness in the experimental group further improved by week 16, whereas there was no further improvement in the control group (figure 8). In addition to the five VAS measures taken weekly, three dependent variables were scored at baseline and endpoint only: Total Myalgic Score, modified FIQ, and Body Pain Drawings. These data were analyzed for significance using the Student’s paired t test and are summarized in Table 4. The Total Myalgic Score in the control group showed no significant change over the 16-week period while the subjects in the experimental group improved significantly from a mean = 30.3 ± 0.99 to a mean = 26.8 ± 1.5 (p<.05). The measure of daily functioning (FIQ) also remained constant for the control subjects across the 16 weeks, while the experimental group improved significantly from mean =7.6 ± 1.8 to a mean =5.3 ± 1.7 (p<.05). The results for the Pain Drawing data were similar to the FIQ. Although Body Pain Drawing Scores for the control subjects dropped somewhat over time, from mean =134 ± 26 to mean =109 ± 23, this was not significant (p=.19). The experimental group improved significantly over time (p<.05) and by endpoint had less reported pain than the sham treatment subjects. As with several of the VAS variables, there was a tendency for subjects in the experimental group to have better scores at the time of group assignment on both the FIQ and Pain Drawing. However, neither difference approached significance (p=.21 and .57 respectively). The correlations of these variables with patient weight were also not significant (r=.32, p=.11;r=.13, p=.52),. Review of the daily diaries and discussion with the subjects revealed that there had been no adverse effects related to the use of the magnetic mattress pad during the trial period. Three of the experimental subjects reported an intensification of their usual FM symptoms, i.e., aches, pains and fatigue, which subsided after the first 7 to 10 days of mattress pad use. One of the sham users noted increased anxiety during the first 2 weeks ofuse.DISCUSSIONThis pilot study was undertaken to determine whether any clinical improvements could be documented in patients with FM as a result of sleeping on a magnetic mattress pad. The results demonstrate that subjects with FM who slept on mattress pads containing permanent magnets delivering 200-600 G to the skin surface, for a 16-week period, when compared to sham controls, experienced statistically significant and clinically relevant pain reduction and sleep improvement. This was evidenced by the self reported improved VAS for pain, sleep, and fatigue, a reduction in the total myalgic score and the subject’s own assessment of her body pain distribution. The diminished pain and enhanced sleep also correlated with improvement in the subject’s functional abilities for performing tasks of daily living as measured by the modified FIQ.

These results are especially salient when compared with drug trials in patients with FM. Major clinical improvement in pain and/or sleep occurs in only 25% of subjects taking tricyclic medications and certain other central nervous system active medications4,28. The efficacy of these medications lessens with time and the incidence of adverse effects is up to 98%3. The placebo effect seen in this study has been reported in other clinical trials of patients with FM29,31,32. Of interest here was the apparent beneficial effect of the firm mattress pad itself. Subjects in both groups reported continued comfort with the hardness of the mattress pad over the first half of the study period correlating with improvement in fatigue on the VAS in both groups. However, this placebo effect leveled off by week 8 in the control subjects, while the experimental group continued to improve over the entire 16- week trial (see Figure 6). Seven of eight outcome measures showed statistically significant improvement in theexperimental group, whereas only one of these eight measures improved significantly in the sham subjects. The only difference between the two groups was the addition of a static magnetic field, suggesting this therapeutic modality was effective for the experimental subjects in this study There is no longer any doubt that weak electromagnetic and static magnetic fields can modulate biochemical processes in biological tissue in a physiologically meaningful manner. Electromagnetic fields in current orthopedic clinical practice have been employed to treat delayed and non-union fractures19,33-36, rotator cuff tendinitis37, spinal fusions38 and avascular necrosis39 and were originally employed for the treatment of infections in the pre-antibiotic era40. Successful double blind clinical studies using non-thermal pulsed radio frequency signals have been reported for chronic wound repair41, acute ankle sprains42, and acute whiplash injuries 43,44. These signals were also shown to increase skin microcirculation in diabetic patients45. There are numerous studies suggesting the mechanism of action of EMF involves ion/ligand binding at regulatory molecules and the increased release of cytokines and even neurotransmitters46-49. At the clinical level EMF are known to reduce edema42 and increase peripheral blood flow45, both of which might be factors in the pain reduction from permanent magnets reported here. However, the exact mechanisms of interaction which result in the pain reduction and sleep improvement observed in this study are still unknown16-25,46,47. The particular magnets used in this study have a surface field strength of approximately 1100 ± 50 G with a dose ofabout 200-600 G being delivered to the subject23-25. This dosage is within the range of reported bioeffects and takes into account the individual’s weight, how much of the body surface contacted the mattress pad and whether the individual was prone, side-lying or supine. The duration of magnetic exposure for any given pain site can not be controlled in such a study. However, it is commonly accepted that magnetic therapy acts as a trigger for a physiologically relevant

biochemical pathway, e.g., peripheral blood circulation and cytokine, release since the magnetic field delivered to tissue is too weak to supply the energy for such processes. Three experimental subjects documented an intensification of their FM symptoms during the first 1 to 2 weeks of mattress pad use. This type of "therapeutic exacerbation", a phenomenon observed by osteopathic physicians, chiropractors, physical therapists and other body workers, is characterized by a temporary worsening of symptoms during the initial weeks of treatment. We are postulating that the small perturbations in the body’s bioelectromagnetic field caused by magnet placement may be evoking the same type of self limited "therapeutic exacerbation". The two recruits who initially excluded themselves from the study had previously experienced an exacerbation of symptoms while using permanent magnets on certain acupuncture points. They reported increased pain, nausea and dizziness while wearing the magnets, but obtained almost immediate relief of the symptoms when the magnets were removed. There are other reports of certain individuals who are particularly sensitive to electromagnetic fields50. This appears to be a subset of the population who should be identified and studied further. The limitations in this exploratory study suggest recommendations for future studies. Stricter selection criteria should be implemented to exclude: subjects who are on morphine-like drugs; subjects who are involved in significant life changes such as marriage or divorce; anyone in the process of settling a medical disability claim; and subjects in whom a psychiatric disorder is a dominant feature. A certain range of weight should also be a selection criterion in order to assure minimal baseline differences between the groups. Subjects should havebaseline VAS scores of at least 4 so as to eliminate a floor effect, i.e., when patient entry scores show low levels of impairment or discomfort, there is little room for measurable improvement. In addition, a lead-in assessment time for the two-week period prior to actually using the mattress pads would provide a more reliable baseline.Actual duration of time spent on the mattress pads and usual sleeping position should be more precisely documented.CONCLUSIONS: The results of this pilot study demonstrate that sleeping for an average of 8 hours per night (prone, supine, or side-lying) on a mattress pad (containing 270 domino shaped ceramic magnets, measuring 2.0 x 4.5 x 1 cm, 4 cm apart and arranged in a pattern of 15 rows across and 18 rows down) which delivers a 200- 600 G static magnetic field, for 16 weeks, provides significant pain relief and sleep improvement in women with FM. Because pharmaceutical agents are associated with a high rate of adverse effects and offer only minimum relief for the majority of patients, we recommend a trial of magnet therapy, as a non-invasive, painless, low risk adjunct to standard medical and physiatric interventions. Further controlled investigation of devices which

incorporate permanent magnets for the treatment of chronic and acute musculoskeletal pain is definitely warranted. A minimum study period of 2 years is recommended to document long-term efficacy, assess the possibility for habituation, and determine optimal dosimetry, including strength of magnetic fields, exposure time and pole orientation. In this manner the efficacy of this promising simple, non-invasive treatment for FM may be properly established.*Magnetherapy, Inc. 950 Congress Avenue, Riviera Beach, FL 33404-6400 (800) 625-9736. Material in this manuscript was presented at the 4th annual meeting of the North American Academy of Magnetic Therapy on January 24, 1998 in Los Angeles, CA and at the 20th annual meeting of the Bioelectromagnetics Society on June 11, 1998 in St. Pete’s Beach, FL.References1. Wolfe F, Ross K, Anderson J, Russell I, Hebert L. The prevalence and characteristics of fibromyalgia in the general population. Arthritis Rheum 1995; 38:19-27.2. The Iowa Persian Gulf Study Group. Self-reported illness and health status among Gulf War veterans. A population-based study. JAMA 1997; 15: 238-245.3. Goldenberg D. Fibromyalgia syndrome a decade later. What have we learned? Arch Intern Med 1999;159:777-85.4. Carette J, Bell MJ, Reynolds WJ, Haraoui B, McCain GA, Bykerk VP et al. Comparison of amitrypline, cyclobenzaprine, and placebo in the treatment of fibromyalgia. A randomized, double-blind clinical trial. Arthritis Rheum 1994; 37:32-40.5. Wigers SH, Stiles TC, Vogel PA. Effects of aerobic exercise versus stress management treatment in fibromyalgia. Scand J Rheumatol 1996; 25: 77-866. Deluze C, Bosia L, Zirbs A, Chantraine A, Vischer TL. Electroacupuncture in fibromyalgia: results of a controlled trial. BMJ 1992; 305:1249-527. Haanen HCM, Hoenderdos HTW,van Romunde LKJ, Hop WCJ, Mallee C, Terwiel JP, et al. Controlled trial of hypnotherapy in the treatment of refractory fibromyalgia. J Rheumatol 1991;18: 72-5.8. Ferraccioli G, Ghirelli L, Scita F, Nolli M, Mozzani M, Fontana, et al. EMG-biofeedback training in fibromyalgia syndrome. J Rheumatol 1987;14: 820-5.9. Goldenberg DL, Kaplan KH, Nadeau MG, Brodeur C, Smith S, Schmid CH. A controlled study of a stress-reduction, cognitive-behavioral treatment program in fibromyalgia. J Musculoskel Pain 1994; 2: 53-66.10. Bassett CAL. Treatment of therapeutically resistant non-union with bone grafts and pulsating electromagnetic fields. Bone Joint Surg 1982;64(8)1214-1220.11. Sisken BF, Walker J. Therapeutic aspects of electromagnetic fields for soft tissue healing. In: Blank M, editor. Electromagnetic Fields. Biological

Interactions and Mechanisms. Washington DC: American Chemical Society, 1995.p.277-87.12. Hong CZ, Lin JC, Bender LF, Schaeffer JN, Meltzer RJ, Causin P. Magnetic necklace: its therapeutic effectiveness on neck and shoulder pain. Arch Phy Med Rehabil 1982;63:462-6.13. Valbona C, Hazlewood CF, Jurida G. Response of pain to static magnetic fields in post-polio patients:a double-blind pilot study. Arch Phys Med Rehabil 1997;78:1200- 3.14. Weintraub MI. Magnetic bio-stimulation in painful diabetic peripheral neuropathy: a novel intervention – a randomized, double-placebo crossover study. Am J Pain Manag 1999;9:8-17.15. Kazuo Shimodaira, San-Ikukai. Summary of a 12 month, double-blind, clinical test of magnetic mattress pads, Tokyo Communication Hospital, Obstetrics and Gynecology, Tokyo, Japan 1990.16. Blank, M, editor. Electromagnetic Fields: Biological Interactions and Mechanisms. Washington DC: American Chemical Society, 1995.17. Markov MS, Pilla AA. Electromagnetic field stimulation of soft tissues. Wounds 1995;7:143-151.18. Bassett CAL. Fundamental and practical aspects of therapeutical uses of pulsed electro- magnetic fields(PEMFs). Critical Review of Biomedical Engineering. 1989:17:451-529.19. Pilla AA. State of the art in electromagnetic therapeutics. In Electricity and Magnetism in Biology and Medicine. M Blank, ed. San Francisco Press 1993.20. Cohen D, Yoram P, Cuffin BN, Schmid SJ, editors. Magnetic Fields Produced by Steady Currents in the Body. Proceedings of the National Academy of Science USA. 1970;77 (3) pp 1447-1451.21. Brighton, C, Pollack, S, editors. Electromagnet in Medicine and Biology. San Francisco: San Fransisco Press, 1991.22. Polk, C, Postow E, editors. Handbook of Biological Effects of Electromagnetic Fields. Boca Raton: CRC Press, 1996.23. Todorov N. Magnetotherapy. Sofia: Medeitzina Physcultura Press, 1982.24. Markov MS, Todorov N. Electromagnetic field stimulation of some physiological processes. StudiaBiophysica 1984; 99: 151-56.25. Markov MS. Biophysical Aspects of the application of electromagnetic fields in orthopedics and traumatology. In Electromagnetic Therapy in Trauma and Diseases of the Support-motor Apparatus. Detlavs, I, ed. Rija : Zinatie Press 1984.26. Wolfe F, Smythe HA, Yunus MB, et al. The American College of Rheumatology 1990 criteria for classification of fibromyalgia: report of the Multicenter Criteria Committee. Arthritis Rheum 1990;

33:160-172.27. Burckhardt CS, Clark SR, Bennett RM. The Fibromyalgia Impact Questionnaire-development and validation. J Rheumatol 1991; 18: 728-33.18.28. Goldenberg DL, Felson DT, Dinerman H: A randomized, controlled trial of amitriptyline and naproxen in the treatment of patients with fibromyalgia. Arthritis Rheum. 1986;29:1371-137729. Moldofsky H, Liu FA, Mously C, Roth-Schechter B, Reynolds WJ The effect of Zolpidem in patient with fibromyalgia: a double-blind, placebo controlled, modified crossover study. J Rheumatol 1996;23:529-33.30. Okifuji A, Turk DC, Sinclair JD, Starz TW, Marcus DA: A standardized manual tender point survey.I.Development and determination of a threshold point for identification of positive tender points in fibromyalgia syndrome. J Rheumatol 1997;24:377-83.31. Carette S, McCain GA, Bell DA, Fam AG. Evaluation of amitriptyline in primary fibrositis: doubleblind, placebo-controlled study. Arthritis Rheum 1986;29:655-659.32. Russell IJ, Fletcher EM, Michalek JE, McBroom PC, Hester GC. Treatment of primary fibrositis/fibromyalgia syndrome with Ibuprofen and alprazolam: a double-blind, placebo-controlled study. Arthritis Rheum 1989;34:552-560.33. Bassett CAL, Pilla AA, Pawluk RJ, A non-surgical salvage of surgically-resistant pseudoarthroses and non-unions by pulsing electromagnetic fields. Clin Orthop 1977;124:117-128.34. Sharrard WJW. A double-blind trial of pulsed electromagnetic fields for delayed union of tibial fractures. J Bone Joint Surg 1990; 72B:347-352.35. Brighton CT. The treatment of non-unions with electricity. J Bone Joint Surg 1981; 63A:847-851.36. Gossling HR, Bernstein RA, Abbott J. Treatment of ununited tibial fractures: A comparison of surgery and pulsed electromagnetic fields (PEMF). Orthopaedics 1992;15:711-719.37. Binder A, Parr G, Hazleman B, Fitton-Jackson S. Pulsed electromagnetic field therapy of persistent rotator cuff tendinitis. Lancet 1984; 8379:695-698.38. Mooney V. A randomized double-blind prospective study of the efficacy of pulsed electromagnetic fields for interbody lumbar fusions. Spine 1990;15:708-711.39. Aaron RK, Lennox D, Bunce GE, Ebert T. The conservative treatment of osteonecrosis of the femoral head. A comparison of core decompression and pulsing electromagnetic fields. Clin Orthop 1989;249:209-216.40. Ginsberg AJ, Ultrashort radiowaves as a therapeutic agent. Med Record 1934;140:651-653.

41. Salzberg CA, Cooper SA, Perez P, Viehbeck MG, Byrne DW. The effects of non-thermal pulsed electromagnetic energy on wound healing of pressure ulcers in spinal cord-injured patients: arandomized, double-blind study. Ostomy Wound Management 1995;41:42-51.42. Pilla AA, Martin DE, Schuett AM, et al., Effect of pulsed radiofrequency therapy on edema from grades I and II ankle sprains: a placebo controlled, randomized, multi-site, double-blind clinical study. J Athl Train 1996; S31:53.43. Foley-Nolan D, Barry C, Coughlan RJ, O’Connor P, Roden D. Pulsed high frequency (27MHz) electromagnetic therapy for persistent neck pain: a double blind placebo-controlled study of 20 patients. Orthopedics 1990;13:445-451.44. Foley-Nolan D, Moore K, Codd M, et al. Low energy high frequency pulsed electromagnetic therapy for acute whiplash injuries: a double blind randomized controlled study. Scan J Rehab Med 1992;24:51-59.45. Mayrovitz H, Larsen P. A preliminary study to evaluate the effect of pulsed radio frequency field treatment on lower extremity peri-ulcer skin microcirculation of diabetic patients. Wounds 1995; 7:90- 93.46. Pilla AA, Muehsam DJ, Markov MS, Sisken BF. EMF signals and ion/ligand binding kinetics: prediction of bioeffective waveform parameters. Bioelectrochemistry and Bioenergetics 1999;48:27-34.47. Muehsam DJ, Pilla AA. The sensitivity of cells and tissues to exogenous fields: effects of target system initial state. Bioelectrochemistry and Bioenergetics 1999;48:35-42.48. Bull AW, Cherng, Jenrow SKA, Liboff AR, Weak magnetostatic fields alter calmodulin-dependent cyclic nucleotide phosphodiesterase activity. In Electricity and Magnetism in Biology and Medicine, M. Blank (ed.), San Francisco Press, 1993, p. 319.49. Nossol B, Buse G, Silny J. Influence of weak static and 50 Hz magnetic fields on the redox activity of cytochrome-c oxidase, Bioelectromagnetics 1993;14:36.50. Starlanyl D, Copeland ME. Fibromyalgia and Chronic Myofascial Pain Syndrome. Oakland: New Harbinger Publications, 1996. p.75. TABLE 1. Baseline demographic characteristics by treatment group.Experimental ControlAge (yrs) 51.15 ± 13.50 48.17 ± 11.09Weight (lbs)* 152.69 ± 37.19 178.33 ± 38.00Months since 34.62 ± 30.81 40.00 ± 12.00diagnosisMarital statusSingle 2 3Married 3 4Other 3 0

Employment statusWorking 10 6Not working 3 6On Medical Disability 1 3*Weight was the only significant variable (p=.005)TABLE 2. Number of subjects in each group using FM related prescribed medications.Medication Experimental ControlAntidepressant 5 7Anti-inflammatory 5 5Anti-psychotic 0 1Anxiolytic 1 6Bladder 0 1Gastrointestinal 2 5Migraine 1 0Muscle relaxant 1 3Narcotic (mild) 0 4Sleep aid 2 2OTHERGuafenesin 0 1TABLE 3. Number of subjects in each group using other therapeutic interventions.Therapy Experimental ControlAcupuncture 5 6Alexander technique 1 0Chiropractic 3 3Craniosacral 4 0Exercise (home program) 4 3Massage 1 2Myofascial release 2 1Myotherapy 2 0Osteopathy 0 1Psychotherapy 1 1Ultrasound 1 0TABLE 4. Overall results from five Visual Analog Scales, Total Myalgic Score, Body Pain DistributionDrawing, and Modified Fibromyalgia Impact Questionnaire by treatment group. Values reported are means ±SEM.Experimental Controln=13 n=12

Start Week 16 PvalueStart Week 16 P valuePain 5.0 ± 0.45 3.4 ± 0.69 .04 5.7 ± 0.79 5.3 ± 0.85 .62Sleep 5.9 ± 0.65 3.5 ± 0.52 .01 6.2 ± 0.80 4.5 ± 0.80 .149Fatigue 6.4 ± 0.60 3.7 ± 0.58 .006 6.9 ± 0.52 5.8 ± 0.71 .176Wellbeing 3.3 ± 0.68 2.6 ± 0.53 .438 5.4 ± 0.73 4.8 ± 0.88 .640Tiredness 6.7 ± 0.80 4.1 ± 0.83 .019 7.3 ± 0.39 5.8 ± 0.75 .043Myalgic Score 30.3 ± 0.99 26.8 ± 1.5 .025 30.6 ± 1.1 30.8 ± 0.61 .821Pain Drawing 116 ± 20 62 ± 12 .015 134 ± 26 109 ± 23 .193FIQ 1 7.6 ± 1.8 5.3 ± 1.7 .033 11.3 ± 2.2 11.6 ± 1.9 .845Figure LegendsFigure 1: Effect on pain of sleeping nightly on a mattress pad delivering 200-600G static magnetic field to female patients with fibromyalgia. Use of a visualanalog scale (VAS) showed mean overall pain decreased significantly by 32% for patients in the experimental group. The mean pain decrease of 7% for the sham treated patients was not significant.Figure 2: Effect on sleep of sleeping nightly on a mattress pad delivering 200-600 G static magnetic field to female patients with fibromyalgia. Use of a visualanalog scale (VAS) showed sleep was significantly improved by 40% for patients in the experimental group. The 27% change for the sham treated patients was not significant.Figure 3: Effect on fatigue of sleeping nightly on a mattress pad delivering 200- 600 G static magnetic field to female patients with fibromyalgia. Use of a visual analog scale (VAS) showed fatigue was significantly decreased by 42% for patients in the experimental group. The 16% change for the sham treated patients was not significant.Figure 4: Effect on tiredness upon awakening of sleeping nightly on a mattresspad delivering 200-600 G static magnetic field to female patients with fibromyalgia. Use of a visual analog scale (VAS) showed tiredness upon awakening decreased by 39% for patients in the experimental group and by 21% for the sham treated patients. These changes were significant in both groups, demonstrating a placebo effect of the magnetic field in this outcome measure , possibly reflecting the added comfort of the mattress pad.Figure 5: Time course of effect of static magnetic field therapy (200-600 G) from mattress pads on pain in fibromyalgia. Each time point represents the mean value for this outcome measure averaged over the prior four-week period. Pain decreased significantly by week 8, with further decreases by week 16 in the experimental group. In contrast there was no significant decrease in pain

throughout the 16-week trial period in the control group. Figure 6: Time course of effect of static magnetic field therapy (200-600 G) from mattress pads on sleep in fibromyalgia. Each time point represents the mean value for this outcome measure averaged over the prior four-week period. Sleep improved significantly by week 16 in the experimental group compared to no change in this outcome measure in the control group throughout the 16-week trial period.Figure 7: Time course of effect of static magnetic field therapy (200-600 G) from mattress pads on fatigue in fibromyalgia. Each time point represents the mean value for this outcome measure averaged over the prior four-week period. Fatigue was significantly less in the experimental group by week 8 and was maintained through week 16. In contrast there was no change in this outcome measure in the control group throughout the 16-week trial period.Figure 8: Time course of effect of static magnetic field therapy (200-600 G) from mattress pads on tiredness upon awakening in fibromyalgia. Each time point represents the mean value for this outcome measure averaged over the prior fourweek period. This measure significantly decreased in both control andexperimental groups by week 8. In addition, both groups continued to decreasesignificantly, at different rates, through week 16. A placebo effect of magneticfield treatment was demonstrated for this outcome measure.16Tiredness (VAS, max=10)012345678StartWeek 16Controln=12Experimentaln=13* p < .04**Time (weeks)2 4 6 8 10 12 14 16 18

Average Monthly Pain (VAS, max=10)234567 ControlExperimental** ** p < .05Time (weeks)2 4 6 8 10 12 14 16 18Mean Monthly Fatigue (VAS, max=10)345678ControlExperimental* *** p < .05Time (weeks)2 4 6 8 10 12 14 16 18Mean Monthly Tiredness (VAS, max=10)345678ControlExperimental*** p < .05Glaucoma Research Study

http://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESIn this study, patients with primary open-angle glaucoma with compensated intraocular pressure were administered magnetotherapyusing an ATOS device with 33-mT magnetic field induction. The procedure was administered to a patient in a sitting posture with a magnetic inductor held before the eye. Sessions lasted 10 minutes and each course included 10 sessions. Following 4-5 months of therapy, results showed improved vision acuity 0.16 diopters, on an average of 29 out of 30 eyes with vision acuity below 1.0. 149References149. Bisvas, et al., "Possibilities of Magnetotherapy in Stabilization of Visual Function in Patients with Glaucoma," Vestn Oftalmol, 112(1), Jauary-March 1996, p. 6-8.Hair Loss Rearch Studieshttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED CIENTIFIC STUDIESThis double-blind, placebo-controlled study examined the effects of pulsed electromagnetic fields on hair loss in men suffering from male pattern baldness. PEMF exposures were administered to the head for 12 minutes and were given weekly or twice weekly over a period of 36 weeks. Results found the PEMF treatment both prevented hair loss and promoted regrowth without side effects.151References151. W.S. Maddin, et al., "The Biological Effects of a Pulsed Electrostatic with Specific Reference to Hair: Electrotrichogenesis," International Journal of Dermatology, 29(6), 1990, p. 446-450.Headache Research Studieshttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESResults of this double-blind, placebo-controlled study demonstrated that the administration of a pulsed magnetic field for less than one hour to headache patients produced significant beneficial effects, as shown subjective patient reports, as well as EEG activity.152 This article reports on the case of an acute migraine patient who was successfully treated with external magnetic fields.153This article examined the effects of millimeter wave therapy in the treatment of 107 patients suffering from headaches of varying causes. Treatment consisted of the Nao-Hu, Bai-Huei, and Hua-Chai acupuncture points being exposed to 5.6- and 4.9-mm wavelengths via the use of "Yav'-1-5.6" or "Electronka-KVCh" devices, respectively. Exposure lasted up to 60 minutes per day over a

course of 10 days. All patients experienced positive results following 3-5 exposures. After one year, 48 percent of patients remained free of headaches, with a significant decrease in another 41 percent.154 This study examined the effects of pulsed electromagnetic fields (20 minutes per day for 15 days) in the treatment of patients suffering from chronic headaches. Results indicated the treatment to be most effective in patients suffering from tension headaches, with 88 percent of such patients reporting positive results. Beneficial results were also experienced patients suffering from migraines (60 percent), cervical migraines (68 percent), and psychogenic headaches (60 percent).155 In this study, 90 headache patients were treated with pulsating electromagnetic fields via large coils to the body for 20 minutes per day for a total of 15 days. Results found the treatment to be either excellent or good for those patients suffering from migraine, tension, and/or cervical headaches. Patients experiencing post-traumatic or cluster headaches did not experience such benefits.156 Results of this study indicated that pulsating electromagnetic fields (12 Hz and 5 mT) were an effective prophylactic treatment for patients suffering from cervical and migraine headaches.157 This placebo-controlled, double-blind study examined the effects of pulsed electromagnetic fields (2-5 Hz and flux densities of 3-4mT) on patients suffering from migraine headaches. PEMFs were administered to the head for 10-15 minutes per day over a period of 30 days. Results showed a mean improvement level of 66 percent in patients receiving the treatment, compared to just 23 percent among controls.158References152. O. Grunner, et al., "Cerebral Use of a Pulsating Magnetic Field in Neuropsychiatry Patients with Long-term Headache," EEG EMG Z Elektroenzephalogr Verwandte Geb, 16(4), December 1985, p. 227-230.153. R. Sandyk, "The Influence of the Pineal Gland on Migraine and Cluster Headaches and Effects of Treatment with picoTesla Magnetic Fields," International Journal of Neurosci, 67(1-4), November-December 1992, p. 145-171.154. B.M. Popov & T.A. Al'shanskaya, "Use of Traditional and Non-traditional Methods in the Treatment of Headache," Millimeter Waves in Medicine and Biology. Digest of Papers of the 11th Russian Symposium with International Participation, April 21-24, 1997, Zvenigorod, Moscow Region, Russia, p.68-71.155. A. Prusinski, et al., "Pulsating Electromagnetic Field in the Therapy of Headache," Hungarian Symposium on Magnetotherapy, 2nd Symposium, May 16-17, 1987, Szekesfehervar, Hungary, p. 163-166.156. A. Prusinksi, et al., "Pulsating Electromagnetic Field in the Therapy of Headache," Journal of Bioelectr., 7(1), 1988, p. 127-128.

157. J. Giczi & A. Guseo, "Treatment of Headache Pulsating Electromagnetic Field a Preliminary Report," Hungarian Symposium on Magnetotherapy, 2nd Symposium, May 16-17, 1987, Szekesfehervar, Hungary, p. 74-76.

158. L. Lazar & A. Farago, "Experiences of Patients Suffering from Migraine-Type Headache Treated with Magnetotherapy," Hungarian Symposium on Magnetotherapy, 2nd Symposium, May 16-17, 1987, Szekesfehervar, Hungary, p. 137-140.

New Finding:Water Can Help Your Heart!Almost every day, new information comes to light on the relationship between water and health. Now, study results published in the American Journal of Epidemiology offer more evidence. The Loma Linda University study followed 20,000 participants over six years, who drank at least 40 ounces of water a day. The results indicate that drinking more water may reduce the risk of heart attach by 45 percent in women and 60 percent for men. The researchers believe that drinking plenty of water could help to prevent life-threatening clots in the bloodstream. Nikken Family Magazine – September/October 2002Hemophilia Research Studyhttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESIn this study, hemophiliacs suffering from joint hemorrhage received millimeter wave (MW) therapy at biologically active points beginning on the first day of hospital release. Adults were treated with an "Electronica-KVCh" device (61 GHz, 5 mW maximum power) and children were treated with a "Porog" device, which generates low-intensity wide-band MMW noise. Exposures in both groups lasted for 20-25 minutes per day and were extended over a period of 10 days. Results indicated the treatment to be more effective than conventional therapy with respect to alleviation of pain, need for medication, and other parameters.159References159. V.V. Aleschenko & I.O. Pisanko, "EHF-Therapy for Hemophylic Arthropathy and Hemarthroses of the Knee Joint," Millimeter Waves in Medicine and Biology. Digest of Papers of the 10th Russian Symposium with International Participation, April 24-26, Moscow, Russia, 1995, p. 61-63.Hepatitis Research Studieshttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESThis double-blind, placebo-controlled study examined the effects of millimeter wave therapy combined with conventional methods in the treatment of viral hepatitis in children. Making use of a "Yav'-1-5,6" or "Yav'-1-7,7" device, MW therapy involved 14-15 exposures of, on average, 30 minutes per day at

wavelengths of either 5.6 or 7.1 mm. Results indicated the combined treatment to be more effective than conventional treatment only, leading to a more rapid restoration of liver function.160 Results of this study showed that the use of magnetic fields was effective in treating patients suffering from viral hepatitis who had previously not benefited from conventional drug therapies.161This study examined the effects of magnetotherapy in children suffering from various forms of viral hepatitis. Magnetotherapy consisted of alternating magnetic fields applied to the liver area daily over a total of 10-15 days. Results indicated magnetotherapy led to more rapid and trouble-free recovery.162References160. A.A. Shul'diakov, et al., "Electromagnetic Radiation of Millimeter Range in Treatment of Children with Acute Viral Hepatitis," Millimeter Waves in Medicine and Biology, 10th Russian Symposium with International Participation, April 24-26, 1995, Moscow, Russia, p. 21-23.161. I.A. Il'inskii, et al., "Experience with the Use of Glucocorticosteroids and Magnetic Fields in the Intensive Therapy of Severe Forms of Viral Hepatitis," Soviet Medicine, 9, 1978, p. 72-74.162. V.V. Krasnov & A.I. Shilenok, "Magnetotherapy of Hepatitis A and B in Children," Pediatriia, 10, 1991, p. 54-57.Herniated Disk Research Studyhttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESThis double-blind, placebo-controlled study examined the effects of magnetotherapy in patients following herniated disk surgery. Results showed that 52 percent of patients receiving the treatment compared to 30 percent of controls reported being free of symptoms at the time of hospital release.163References163. K. Perjes, et al., "Effect of Magnetotherapy on Recovery After Herniated Disk Surgery," Hungarian Symposium on Magnetotherapy, 2nd Symposium, May 16-17, 1987, Szekesfehervar, Hungary, p. 159-162.Hip Problems Research Studieshttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESThis double-blind study examined the effects of pulsed electromagnetic fields on loosened hip prostheses. Results showed an increase of bone density in all patients receiving PEMF treatment compared to only 60 percent of controls. The authors argue such findings suggest PEMF elicits early bone reconstruction, which enhances early weight bearing.164 This study examined the effects of pulsed electromagnetic fields (50 Hz, 50 G) in treating aseptic loosening of total hip prostheses. PEMF therapy consisted of 20 minutes per day for 6 days per week over a total of 20 such sessions and was begun, on

average, a year and a half following the start of loosening. Results showed PEMF to have some beneficial effects with respect to loosened hip arthroplasties, although it was not effective in patients suffering severe pain due to extreme loosening.165References164. G. Gualtieri, et al., "The Effect Pulsed Electromagnetic Field Stimulation on Patients Treated of Hip Revesions with Trans- Femoral Approach," Second World Congress for Electricity and Magnetism in Biology and Medicine, 8-13 June 1997, Bologna, Italy.165. K. Konrad, "Therapy with Pulsed Electromagnetic Fields in Aseptic Loosening of Total Hip Protheses: A Prospective Study," Clinical Rheumatology, 15(4), 1996, p. 325-328.Incontinence Research Studyhttp://www.thirdage.com/news/archive/ALT02991227-03.html?hnavA new study found 61 percent of women treated had a 50 percent better reduction in incontinence episodes. The research was presented at the International Bladder Symposium in Washington, D.C. Test subjects were treated with Extracorporeal Magnetic Innervation therapy, a painless, non-invasive 20-minute treatment twice a week for a number of weeks. The study says a third of the women reported absolutely no leakage following the therapy, known as NeoControl by brand. Dr. Peter Sand of Evanston Northwestern Healthcare in Illinois says such a long-term response without continued treatment is not seen after other therapies.Gangrene on Diabetic Non-healing Wound on Sole &Results from Using Infrared Led Light TherapyBefore Before After Before AfterResults from using infrared led light therapy – Nikken’s new KenkoWave20th World Congress of Dermatology, Paris, July 2002 Non-healing Diabetic Ulcer treated using 660nm Red PhototherapyDr. Bipin Deshpande,M.B.B.S, D.V.D., Consulting Dermatologist, PunePurpose of studyTo assess the efficacy of 660nm Red Light LED Phototherapy for treating Non-healing Diabetic Ulcer.MethodsA 75-year male diabetic patient who had medicine controlled congestive cardiac failure (CCF) & peripheral neuropathy developed a non-healing ulcer over left sole following trauma. Examination & investigations revealed normal blood sugar & signs of peripheral neuropathy of both legs without vasculopathy. Patient had already taken all routine treatments for non-healing wound in form of antibiotics, dressings, wound care management for 6 months,

which had failed. Initially, he was given a course of Cefadroxil 500mg BD for one week to clear wound sepsis. Insulin was used to control Diabetes.Wound size was 4cmx7cm at the start of the Phototherapy. 660nm narrow band low energy red light was used for treatment of the wound on alternate days (16 min. at a time). This therapy was given for 5 weeks, which led to complete wound healing. Proper photography & follow-up was done for one year.Summary of resultsRapid & excellent wound healing was seen. Wound healed totally in 15 phototherapy sessions spread over 5 weeks.New epithelium was thin, having good texture & without fibrosis. There was no recurrence till today.Conclusion660nm Red Light Phototherapy was found to be very effective for healing of this Non-healing Diabetic Ulcer where routine treatment failed.Insomnia Research Studieshttp://www.mediconsult.com/mc/mcsite.nsf/condition/sleep~journal+articles~MCOR-47WMUSElectromagnetic field works better than sleeping pills without side effects. To test that hypothesis, researchers recruited 106 volunteers with insomnia through the Scripps Clinic in La Jolla, California, and the University of Colorado Health Sciences Center in Denver. Slightly over half of the subjects were women, and their average age was 40. Their sleeping patterns were assessed using polysomnography, a complete sleep evaluation that monitors breathing, heartbeat, eye movement, muscle movement and a range of other factors. Comparisons of the two groups showed that the group receiving electromagnetic signals had slightly worse insomnia by standard measuresgoing into the test period. At the end of the four-week period, researchers compared the somnographic records of both groups, and found that while a placebo effect had increased total sleep time in the dummy-device patients by about 13 minutes, the group using electromagnetic signals had gained an average of over an hour-and-a-quarter in extra sleep, a 26% gain. They were also far ahead in two other basic parameters of sleep: sleep latency (the number of minutes spent in bed before dropping off) and sleep efficiency (the total amount of time asleep as a proportion of the total amount of time spent in bed trying to sleep). Again a placebo effect had reduced latency in the dummy group by about six minutes to an average of about 28 minutes, but the electromagnetic group's average latency had fallen by almost 22 minutes to just over 18 -- a reduction of over half to a level that's considered normal for human sleep. Sleep efficiency in the dummy group increased by 5.5% to 73.7%, while in the electromagnetic group it climbed 16% to 78.6% (it had been worse to

start with). In the volunteers with the worst insomnia, who fell in the bottom 50% on all sleep parameters, total sleep time with the electromagnetic signals increased by an average one hour 42 minutes. The patterns of sleep appeared to have changed, too. There was a three times greater increase in rapid-eye movement (REM) sleep in the electromagnetic group than in the placebo group. That change has important implications in terms of sleep quality and restorative value. The electromagnetic group was going through a more natural sleep progression, with 30% more cycles -- a different result from that normally obtained with sleeping pills, which tend to suppress certain natural sleep stages. There was also less time spent awake after first falling asleep -- 55 minutes less -- in the electromagnetic group, as opposed to only about 31 minutes less in the dummydevice group. Finally, unless one includes increased awareness of dreaming as a side effect, there were no negative changes associated with the use of the electromagnetic signals. It appears to produce a more natural sleep than pharmacological remedies, but without memory loss, mood changes, daytime drowsiness or hangover. Most of those patients who did dream more considered it a positive change, and most sleep specialists would agree that it islikely to indicate physiologically more valuable sleep. Electromagnetic signals therapy also did not appear to be weakened by rebound insomnia, as are many drugs. Indeed, subjective data analysis from other studies suggests that while benzodiazepines give their best results in the first week of use and then become less effective, electromagnetic signals doesn't really begin working until the seventh or eighth treatment (about 18 days). We have the first therapy ever to increase the number of sleep cycles, and that's what many sleep authorities suchas Dr. Thomas Roth or Dr. Christian Guilleminault have told us -- that they've never seen any sleeping pill that could increase the number of sleep cycles. Restoring sleep cycles is the key to reproducing real physiological sleep, because that means that the patient is reaching the stage of deepest sleep. Sleep stages are separated by the REM stage of rapid-eye movement, when you move, dream, roll your eyes, and have an erection if you're a man. Hence, the number of REM periods tells us the number of sleep stages achieved. We found that patients using the electromagnetic signals averaged significantly more periods of REM each night than the placebo group. When we analyzed them, these sleep cycles had normal duration and structure. We've looked at more than 1,000 patients, and followed them up for several years. The only side effect that we noticed was increased dreaming. It seems, therefore, to be safe and well-tolerated. We went to the FDA and got a green light to file. We haven't yet filed for pre-market approval, but we hope to do so next year.Joint Disease Research Studieshttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIES

Results of this 11-year study involving 3014 patients found pulsed magnetic field treatment at low frequencies and intensities to be a highly effective, side-effect-free therapy for joint disease.168References168. E. Riva Sanseverino, et al., "Therapeutic Effects of Pulsed Magnetic Fields on Joint Diseases," Panminerva Med, 34(4), October-December 1992, p.187-196.Bio-Directed Joint Research StudyA recent research study was done on Nikken’s Bio-Directed Joint formula by independent research groups outside of Nikken. It showed that the joint product is effective on over 96% of the people who take it. We now have clinical proof...CLINIAL TRIAL SUMMARY:A randomized double blind Phase III placebo study was done on 93 sufferers of osteo-arthritis, who have been diagnosed with OA for an average of 6 years. 52 men and 41 women, aged 37-77 over a period of 60 day treatment period w/ Cetyl Meristoliate (CMC) which s the major active in Nikken's joint product.Half of the population got the CM complex (6 CMC capsules per day) Half got the placebo (6 vegetable oil capsules per day) (the capsules were indistinguishable) Total of 153 affected joints in this population. 139 had painful swelling. 100 had stiffness associated with degrees of deformity.25 included some soft tissue involvement. Clinical assessments were conducted in 3 visits over the 60 day period - Day 0, Day 30, and Day 60 Three major areas of investigation: Pain Range of motionPhysical activity indicatorsRange of motion (physician assessment):Participants lay face down and flex leg to determine maximum angle of flexion using gorionimeters (sp?) Also questionnaires: completed at each visit - Lequesne Indices baseline)Range of Motion Results:Day 0:CMC - 86 degreesPlacebo - 82 degreesDay 30:CMC - 93 degreesPlacebo - 84 degreesDay 60:CMC - 96 degreesPlacebo - 83 degreesWalking Capabilities:

Maximum distance you can walk in 15 minutes.Day 0:CMC - 700 feetPlacebo - 700 feetDay 60:CMC - 2300 feetPlacebo - 700 feetWalking Up and Down Stairs:Walking Upstairs -CMC - 35% improvementPlacebo - 12% improvementWalking Downstars -CMC - 43% improvementPlacebo - 11% improvementKnee Bending:More than 2-fold improvementDay 30 -CMC - 17% improvementPlacebo - 7% improvementDay 60 -CMC - 23% improvementPlacebo - 12% improvementKidney Research Studyhttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESThis review article notes that placebo-controlled studies have shown positive results concerning the use of pulsed magnetic field therapy in the treatment of secondary chronic pyelonephritis.171References171. V.A. Kiyatkin, "Pulsed Magnetic Field in Therapy of Patients with Secondary Chronic Pyelonephritis," Second World Congress for Electricity and Magnetism in Biology and Medicine, 8-13 June 1997, Bologna, Italy.Liver ResearchIn a double-blind study of sixty people with alcohol-related diseases (damaged livers), 70% had normalized their liver enzymes after only 30 days’ usage of our Liver Formula in therapeutic doses (3 capsules twice each day). The Bio-Directed Liver is very important for every one to take. The liver is a critical organ with primary responsibility for detoxification. To learn more about liver function, visit this informative site:http://www.liverdoctor.com/Some important points about Nikken’s Bio-Directed Nutritionals:

- Bio-directed means the ingredients target specific tissues in the body. Every product has everything you need for that particular area. Like the digestion has the herbs, enzymes, etc. that you need. The womens has all that you need for hormonal health and bone health.- The formulas are customized to compliment Nikken’s other technologies. Everything works synergistically together.- The formulas are proprietary, produced only for Nikken under the highest pharmaceutical standards – USP (U.S. Pharmacopeia).- Design allows all to be taken – without concern over too much of anything. You can take all of the nutritionals without worrying about taking too much of anything.- They are all whole foods with all the good left in tack.Lou Gehrig's Disease Research Studyhttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESThis study reports on three patients with amyotrophic lateral sclerosis who experienced beneficial effects following treatment consisting of three sessions per week of pulsed magnetic fields administered via a Magnobiopulse apparatus. Patients received upwards of 75 total sessions prior to achieving maximum recovery.3References3. A. Bellosi & R. Berget, "Pulsed Magnetic Fields: A Glimmer of Hope for Patients Suffering from Amyotrophic Lateral Sclerosis," Second World Congress for Electricity and Magnetism in Biology and Medicine, 8-13 June 1997, Bologna, Italy.Lung Disease Research Studyhttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESThis study examined the effects of low-frequency magnetic fields coupled with conventional therapies in rats suffering from inflammatory lung disease. Results showed that rats receiving the magnetic fields experienced significant reductions in lung abscesses and associated symptoms, and similar beneficial effects were seen among a group of 165 human patients receiving comparabletreatment.177References177. L.V. Iashchenko, "Low-Frequency Magnetic Fields in the Combined Therapy of Inflammatory Lung Diseases," Probl Tuberk, 3, 1988, p. 53-56.Lupus Erythematosus Research Studieshttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIES

This review article examined the data concerning impulsed magnetic fields in the treatment of lupus erythematosus. Studies indicate that the treatment can be beneficial due to its anti-inflammatory and analgesic effects, its positive action on microcirculation, and immunological reactivity.178 This double-blind, placebo-controlled study examined the effects of UHF and microwave therapy in treating patients suffering from systemic lupus. Twenty-six patients were given 30-35 W of microwave irradiation administered to the adrenal region. Twenty-five patients were given 30-35 W UHF administered bilaterally to the temporal region. The treatment regimen for both groups included 18-20 daily sessions. A group of 11 patients were used as controls. Results showed both treatments to be effective, with 27 percent of microwave patients and 66 percent of UHF patients reporting total elimination of polyarthralgia, myalgia, and painful contractures.179 Results of this study indicated that the bitemporal application of ultrahigh-frequency electromagnetic fields to the hypothalamohypophyseal area daily over a period of 18-20 days had beneficial effects in patients suffering from systemic lupus erythematosus.180References178. I.V. Khamaganova, et al., "The Use of a Pulsed Magnetic Field in the Treatment of Lupus Erythematosus," Ter Arkh, 67(10), 1995, p. 84-87.179. V.D. Sidorov & S.B. Pershin, "Immunomodulating Effect of Microwaves and Ultrahigh Frequency Electric Field in Patients with Systemic Lupus Erythmatosus," Bioelectrochem Bioenerg, 30, 1993, p. 327-330.180. V.D. Sidorov, et al., "The Immunomodulating Effect of Microwaves and of an Ultrahigh-Frequency Electrical Field in Patients with Systemic Lupus Erythematosus," Vopr Kurortol Fizioter Lech Fiz Kult, (4), 1991, p. 36-40.Magnetic Insoles StudyDate: 6/26/2001The following is a brief report on how magnetic insoles help reduce balanceproblems. Effect of magnetic insoles on postural sway measures in men andwomen during a static balance test. Suomi R, Koceja DM. School of Health, Exercise Science and Athletics, University of Wisconsin-Stevens Point 54481, USA. rsuomi@uwsp.edu - states that numerous anecdotal reports have suggested a growing public enthusiasm for magnetic devices for treatment of pain and various motor and sensory dysfunction's. In this study the effectiveness of magnetic insoles on postural sway measures during a single application were investigated. Twenty-eight adults were assessed on postural sway measures while performing a static twolegged stance test on a Kistler force platform under two treatment conditions (magnetic insoles, non-magnetic insoles). Significant reductions in total sway area and lateral sway scores were obtained by the older adults while standing on the magnetic insoles. These

preliminary results indicate that treatment of postural instability using magnetic insoles are a viable alternative for older adults.Magnetic Mattress Pads Research StudySummary of a 12-month, double-blind, clinical test of magnetic mattress pads carried out by San-ikukai Hospital, Tokyo Communications Hospital and Kouseikai Suzuki Hospital, by Dr. Kazuo Shimodaira.The mattress pads used in this study were typical full-size pads containing 124 permanent ferrite magnets with magnetic field strengths of 750-950 gauss each. The pads themselves were made oil two sheets of felt with the magnets sandwiched between them. The felt sheets were then wrapped in a cloth cover. 'The total number of subjects of this double-blind clinical experiment was 43 l (216 male, 215 female). 375 subjects were given the magnetic pads, 56 were given non-magnetic pads. None of the 431 subjects knew which pad they were sleeping on. Subjects selected for the experiment were those with chief complaints related to:Neck and shoulder painBack and lower back painBack pain (general)Lower limb painInsomniaFatigueTo determine the presence of any side effects, blood pressure, hemoglobin, number of erythrocytes, and number of leucocytes were examined before and after the use of the mattress pads. Besides blood sedimentation, and TP, COL, ALP, GOT, GPT, Na, and K were also examined, as were functions of the kidneys, liver, pancreas, and the entire circulatory system.ResultsPositive No#Symptom Cases Results % Results %Neck and 66 47 71.2 19 28.8shoulder painBack and lower 76 61 80.3 15 19.7back painBack pain 31 25 80.7 6 19.3(general)Lower limb pain 68 54 79.4 14 20.6Insomnia 70 61 87.1 9 12.9Fatigue 64 53 82.8 11 17.2Out of 375 total subjects with symptoms, 301 (80.27%) reported positive results. 74 cases (19.73%) reported no results.Time of Response

The percentage of subjects who realized the effect of the magnetic mattress pad within 3 days:Neck and shoulder pain 46.9%Back and lower back pain 50.0%Back pain 38.7%Lower limb pain 54.4%Insomnia 64.3%Fatigue 57.8%Out of 375 total subjects who slept on the magnetic mattress pads, 200 (53.3%) realized the effects within 3 days. Over 70% realizedthe effects within 5 days.Conclusion:Dr. Shimodaira's conclusion of this year-long study conducted in 3 of Japan's foremost hospitals: "The magnetized health mattress pad is proved to be effective on neck and shoulder pain, back and lower back pain, back pain, lower limb pain, insomnia, and fatigue, and to have no side effects."Magnetic Research & Library InformationFrom Nikkens websitehttp://www.5pillars.com/Content/Mind/Index.cfm?url=MagneticResearch4-2001.htmlMultiple Sclerosis Research StudiesFrom: http://www.tnp.com/encyclopedia/therapy/1/5/Multiple Sclerosis A 2-month double-blind placebo-controlled study of 30 individuals with multiple sclerosis was conducted using a PEMF device.13 Participants were instructed to tape the device to one of three different acupuncture points on the shoulder, back, or hip. The study found statistically significant improvements in the treatment group, most notably in bladder control, hand function, and spasticity.---------------------------------------------------------------------------------From: http://www.micronauts.com/magnetic.htmA study published in the 1989 journal of Psyschoenergetics reported an 80% improvement in multiple sclerosis patients. This was a double blind study using almost 100 patients.---------------------------------------------------------------------------------Study reported in the book “The Pain Relief Break Through” by Julian Whitaker:Dr. Reuven Sandyk, now associated with Tuoro College in Dix Hills, New York, conducted a case study, on the effect of an extremely low electromagnetic field on a 55 year old woman with MS. When the patient came to Sandyk, she was in bad shape. Her legs ere numb. She could not stand

without a cane, and she could hardly walk at all. She was incontinent and her speech was garbled and hoarse. She felt exhausted, had memory lapses, andfound it difficult to do simple arithmetic. Her vision had faded to the point where she could only barely read a newspaper. She was hardly able to draw even a very simple picture of a house. The woman was exposed to electromagnetic treatments. The first treatment, which lasted 20 minutes, was a sham; the magnet device was simply not turned on. The second treatment, lasting the same length of time, exposed her to an electromagnetic force of 7.5picotesla with a frequency of 5 Hz.The results, even as couched in Dr. Sandyk’s conservative, muted words, were spectacular: “While placebo magnetic treatment produced no change in the patient’s motor disability or drawing performance, treatment with MF resulted in an almost immediate clinical response, with the patient reporting improvement of vision with images appearing clearer and brighter.” She rosefrom her chair faster, was less unsteady, and even walked for several minutes without the support of a walker. She reported that she had immediately experienced a feeling of relaxation and mood elevation, and it was noted that she smiled spontaneously several times. The woman was asked to repeat the drawing of a house and showed improved performance, adding further details that suggested enhancement of “visuoconstructive abilities.” A week after the electromagnetic treatment, the woman reported that she had felt more energetic and more optimistic during the preceding week. She said her head felt “clearer,” and her concentration had improved. Sleep had also improved, in part due to “stabilization of her bladder functions.” Her legs felt stronger, the numbness in the lower extremities was less, and her balance was better. She was able to walk in her apartment with greater stability, sometimes using only a cane. Best of all, she reported no side-effects.---------------------------------------------------------------------------------From: http://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESFollowing are descriptions of recent studies, published in peer-reviewed scientific journals, on the impact of treatment with magnetic fields on Multiple Sclerosis:1. This article on Multiple Sclerosis reports on the case of a 55-year-old female chronic progressive multiple sclerosis patient who received a single external application of low magnetic fields (7.5- picotesla; 5-Hz frequency) which lasted 20 minutes. The treatment quickly led to improvements in a variety of areas, including fatigue, sleep, vision, bladder function, movement and speech problems, and mood.182

2. This study reports on four cases of multiple sclerosis who experienced improvements in visuospatial and visuomotor functions following treatment with external application of low magnetic fields.1833. This article reports on the case of a 50-year-old female chronic progressive multiple sclerosis patient who received a single external application of low magnetic fields who experienced significant improvements following the treatment.1844. This article reports on the cases of three patients suffering from long-time symptoms of multiple sclerosis who received treatment with extracerebral pulsed electromagnetic fields over a period of between 6 and 18 months. Results showed all three patients experienced significant improvements in cognitive functions.1855. This is a report on the cases of two chronic multiple sclerosis patients exhibiting severe speech problems. Symptoms were completely resolved following 3-4 weeks of treatment with pulsed electromagnetic fields.1866. This article reports on the cases of three multiple sclerosis patients suffering from alexia (lack of understanding of written words) who experienced a reversal of the alexia following the start of picotesla-range electromagnetic field treatment.1877. This article reports on the case of a middle-aged disabled female patient with a 19-year history of chronic relapsing-remitting multiple sclerosis. Within one day of receiving experimental treatment with picotesla electromagnetic fields, the patient exhibited improvements in her condition. The patient continued with 1-2 treatments per week over a period of 32 months. During this time, significant improvements were seen with respect to a range of physical symptoms, as well as cognitive functions.188 8. The cases of three female multiple sclerosis patients exhibiting suicidal behavior are discussed in this article. Treatment with pulsed picotesla-level electromagnetic fields resolved the suicidal behavior in all three patients, an improvement that was maintained over a follow-up period of 3.5 years.189 9. This article reports on the case of a 36-year-old man severely disabled with partial paralysis and lack of coordination. Three treatment sessions per week with pulsed electromagnetic fields over a period of one year led to a range of improvements, including improvements in gait, balance, bowel and bladder functions, vision, mood, and sleep. No progression of symptoms associated with multiple sclerosis was seen throughout the course of EMF treatment.190 10. This article reports on the cases of two multiple sclerosis patients suffering from chronic ataxia who performed poorly on human figure drawing tests administered to measure body image perception. Treatment with extracerebral applications of picotesla flux

electromagnetic fields led to improvements in gait and balance as well as a normalization in body image perception as seen on a repeat of the same test each patient.19111. This article reports on the case of a 51-year-old female patient with remitting-progressive multiple sclerosis who experienced a successful reduction in carbohydrate craving believed to be associated with the exacerbation of her condition following treatment with a series of extracranial AC pulsed applications of picotesla flux intensity electromagnetic fields.192 12. This article reports on the cases of three multiple sclerosis patients suffering from a chronic progressive course of the disease who experienced a reduction in tremors following treatment with brief external applications of pulsed EMFs of 7.5-pT intensity.19513. This article reports on the cases of three female chronic multiple sclerosis patients who experienced a reversal of cognitive deficits following treatment with brief external applications of alternating pulsed electromagnetic fields in the picotesla range of intensity.19614. This article reports on the cases of three female multiple sclerosis patients with poor word fluency who experienced a 100-percent increase in word output following 4-5 sessions of treatment with external applications of extremely weak electromagnetic fields in the picotesla range of intensity.19715. This article reports on the case of a 58-year-old male multiple sclerosis patient with a 37-year history of the disease. Treatment with external application of magnetic fields in the picotesla range led to a speedy improvement of neurological symptoms in the areas of walking, balance, sensory symptoms, and bladder function. Improvements in numerous cognitive functions were seen within 24 hours of treatment as well.19816. This article reports on the case of a 36-year-old multiple sclerosis patient who experienced immediate improvements in visuoperceptive functions following treatment with external application of picotesla-range magnetic fields.19917. This article reports on the cases of three multiple sclerosis patients suffering from falls due to rapid deterioration in balance and triggered distracting external auditory stimuli. Treatment with a series of extracranially applied, low-frequency picotesla-range intensity electromagnetic fields quickly resolved such symptoms associated with a loss of balance.20018. This article reports on the cases of three multiple sclerosis patients experiencing continuous and debilitating daily fatigue over the course of several years. Treatment with extracranially applied picotesla flux electromagnetic fields dramatically improved symptoms of fatigue in all three patients.20119. This article reports on the cases of two female patients with chronic progressive-stage multiple sclerosis who suffered from regular worsening of

their symptoms starting approximately a week prior to menstruation and abating at menstruation onset. Such symptoms were resolved in both patients two months following the start of treatment with the extracranial application of weak electromagnetic fields.20520. This article reports on the case of a 64-year-old female patient with a 22-year history of chronic progressive multiple sclerosis. Two 30-minute treatments with low-level electromagnetic fields produced a marked improvement in a variety of symptoms.20721. Results of this double-blind, placebo-controlled study found that pulsed electromagnetic fields administered daily over a period of15 days proved to be an effective treatment in reducing spasticity and incontinence associated with multiple sclerosis.20922. Results of this double-blind, placebo-controlled study indicated that pulsed electromagnetic fields administered daily over a period of 15 days is a generally effective treatment in reducing symptoms associated with multiple sclerosis, with the most positive improvements involving the alleviation of spasticity and pain.21023. Results of this double-blind, placebo-controlled study indicated that exposure to magnetic fields produced beneficial clinical effects in patients suffering from cerebral paralysis and in patients with multiple sclerosis.211References182. R. Sandyk, "Rapid Normalization of Visual Evoked Potentials picoTesla Range Magnetic Fields in Chronic Progressive Multiple Sclerosis," International Journal of Neurosci, 77(3-4), August 1994, p. 243-259.183. R. Sandyk, "Further Observations on the Effects of External picoTesla Range Magnetic Fields on Visual Memory and Visuospatial Functions in Multiple Sclerosis," International Journal of Neurosc, 77(3-4), August 1994, 203-27184. R. Sandyk, "Successful Treatment of Multiple Sclerosis with Magnetic Fields," International Journal Neurosci, 66(3-4), October 1992, p. 237-250.185. R. Sandyk, "Progressive Cognitive Improvement in Multiple Sclerosis from Treatment with Electromagnetic Fields," International Journal of Neurosci, 89(1-2), January 1997, p. 39-51.186. R. Sandyk, "Resolution of Dysarthria in Multiple Sclerosis Treatment with Weak Electromagnetic Fields," International Journal of Neurosci, 83(1-2), November 1995, p. 81-92.187. R. Sandyk, "Reversal of Alexia in Multiple Sclerosis Weak Electromagnetic Fields," International Journal of Neurosci, 83(1-2), November 1995, p. 69-79.

188. R. Sandyk, "Long Term Beneficial Effects of Weak Electromagnetic Fields in Multiple Sclerosis," International Journal of Neurosci, 83(1-2), November 1995, p. 45-57.189. R. Sandyk, "Suicidal Behavior is Attenuated in Patients with Multiple Sclerosis Treatment with Electromagnetic Fields," International Journal of Neurosci, 87(1-2) October 1996, p. 5-15.190. R. Sandyk, "Treatment with Electromagnetic Field Alters the Clinical Course of Chronic Progressive Multiple Sclerosis--A Case Report," International Journal of Neurosci, 88(1-2), November 1996, p. 75-82.191. R. Sandyk, "Effect of Weak Electromagnetic Fields on Body Image Perception in Patients with Multiple Sclerosis," International Journal of Neurosci, 86(1-2), July 1996, p. 79-85.192. R. Sandyk, "Treatment with Weak Electromagnetic Fields Attenuates Carbohydrate Craving in a Patients with MultipleSclerosis," International Journal of Neurosci, 86(1-2), July 1996, p. 67-77.193. R. Sandyk, "Reversal of an Acute Parkinsonian Syndrome Associated with Multiple Sclerosis Application of Weak Electromagnetic Fields," International Journal of Neurosci, 86(1-2), July 1996, p. 33-45.194. R. Sandyk & L.C. Dann, "Resolution of Lhermitte's Sign in Multiple Sclerosis Treatment with Weak Electromagnetic Fields," International Journal of Neurosci, 81(3-4), April 1995, p. 215-224.195. R. Sandyk & L.C. Dann, "Weak Electromagnetic Fields Attenuate Tremor in Multiple Sclerosis," International Journal of Neurosci, 79(3-4), December 1994, p. 199-212.196. R. Sandyk, "Reversal of Visuospatial Hemi-inattention in Patients with Chronic Progressive Multiple Sclerosis Treatment with Weak Electromagnetic Fields," International Journal of Neurosci, 79(3-4), December 1994, p. 169-184.197. R. Sandyk, "Improvement in Word-fluency Performance in Patients with Multiple Sclerosis Electromagnetic Fields," International Journal Neurosci, 79(1-2), November 1994, p. 75-90.198. R. Sandyk & R.P. Iacono, "Improvement PicoTesla Range Magnetic Fields of Perceptual-motor Performance and Visual Memory in a Patient with Chronic Progressive Multiple Sclerosis," International Journal of Neurosci, 78(1-2), September 1994, p. 53- 66.199. R. Sandyk & R.P. Iacono, "Multiple Sclerosis: Improvement of Visuoperceptive Functions PicoTesla Range Magnetic Fields," International Journal of Neurosci, 74(1-4), January-February 1994, p. 177-189.200. R. Sandyk, "Application of Weak Electromagnetic Fields Facilitates Sensory-motor Integration in Patients with Multiple Sclerosis," International Journal of Neurosci, 85(1-2), March 1996, p. 101-110.

201. R. Sandyk, "Treatment with Weak Electromagnetic Fields Improves Fatigue Associated with Multiple Sclerosis," International Journal of Neurosci, 84(1-4), February 1996, p. 177-186.202. R. Sandyk, "Resolution of Partial Cataplexy in Multiple Sclerosis Treatment with Weak Electromagnetic Fields," International Journal of Neurosci, 84(1-4), February 1996, p. 157-164.203. R. Sandyk, "Weak Electromagnetic Fields Restore Dream Recall in Patients with Multiple Sclerosis," International Journal of Neurosci, 82(1-2), May 1995, p. 113-125.204. R. Sandyk, "Weak Electromagnetic Fields Improve Body Image Perception in Patients with Multiple Sclerosis," International Journal of Neurosci, 82(3-4), June 1995, p. 285-302.205. R. Sandyk, "Premenstrual Exacerbation of Symptoms in Multiple Sclerosis is Attenuated Treatment with Weak Electromagnetic Fields," International Journal of Neurosci, 83(3-4), December 1995, p. 187-198.206. R. Sandyk & K. Derpapas, "Successful Treatment of an Acute Exacerbation of Multiple Sclerosis External Magnetic Fields," International Journal of Neurosci, 70(1-2), May 1993, p. 97-105.207. R. Sandyk & R.P. Iacono, "Resolution of Longstanding Symptoms of Multiple Sclerosis Application of PicoTesla Range Magnetic Fields," International Journal of Neurosci, 70(3-4), June 1993, p. 255-269.208. R. Sandyk & K. Derpapas, "Magnetic Fields Normalize Visual Evoked Potentials and Brainstem Auditory Evoked Potentials in Multiple Sclerosis," International Journal of Neurosci, 68(3-4), February 1993, p. 241-253.209. A. Guseo, "Double-Blind Treatments with Pulsating Electromagnetic Field in Multiple Sclerosis," Hungarian Symposium on Magnetotherapy, 2nd Symposium, May 16-17, 198 , Szekesfehervar, Hungary, p. 85-89.210. A. Guseo, "Pulsing Electromagnetic Field Therapy of Multiple Sclerosis the Gyuling-Bordacs Device: Double-Blind, Cross-Over and Open Studies," Journal of Bioelectr., 6(1), 1987, p. 23-35.211. A. Sieron, et al., "The Variable Magnetic Fields in the Complex Treatment of Neurological Diseases," European Bioelectromagnetics Association, 3rd International Congress, 29 February - 3 March 1996, Nancy, France.Muscle Injury Research Studieshttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED CIENTIFIC STUDIESThis study examined the effects of pulsed electromagnetic fields on recovery following muscle injury in rats. Results showed that both pulsed and constant magnetic fields were equally effective, with the constant field being more intense.212 This study examined the effects of pulsed electromagnetic fields (Gyuling-Bordacs device) in patients suffering from peripheral muscle

paralysis. Treatment consisted of 20-minute exposures (2-50 Hz, 70 G). Results showed 50-Hz pulsed electromagnetic fields to be the most effective level of treatment and that such therapy enhanced muscle irritability in peripheral paralysis patients as well as in healthy controls.213References212. I.E. Detlav, "The Influence of Constant and Pulsed Electromagnetic Fields on Oxidation Processes in Muscle," in I.E. Detlav, (ed.), Electromagnetic Therapy of Injuries and Diseases of the Support-Motor Apparatus. International Collection of Papers, Riga, Latvia: Riga Medical Institute, 1987, p. 12-16.213. L. Mecseki, et al., "The Study of the Efficacy of Magnetotherapy in Peripheral Paralysis," Hungarian Symposium on Magnetotherapy, 2nd Symposium, 16-17 May 1987, Szekesfehervar, Hungary, p. 149-158.

Neck Pain Research Study

http://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESThis double-blind, placebo-controlled study examined the effects of low-energy pulsed electromagnetic fields administered via soft collars on patients suffering from persistent neck pain. Results indicated significantly beneficial effects following three weeks of treatment.214References214. D. Foley-Nolan, et al., "Low Energy High Frequency (27.12 MHZ) Therapy for Persistent Neck Pain. Double Blind Placebo Controlled Trial," Bioelectromagnetics Society, 12th Annual, June 10-14, 1990, San Antonia, TX, p. 73.Bactericidal Effects of Negative Air Ions on Airborne and SurfaceSalmonella Enteritidishttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=Pub Med&list_uids=11198431&dopt=AbstractSeo KH, Mitchell BW, Holt PS, Gast RK.USDA/ARS Southeast Poultry Research Laboratory, Athens, Georgia 30605, USA. The bactericidal effect of high levels of negative ions was studied using a custom-built electrostatic space charge device. To investigate whether the ion-enriched air exerted a bactericidal effect, an aerosol containing Salmonella

Enteritidis (SE) was pumped into a sealed plastic chamber. Plates of XLT4 agar were attached to the walls, top, and bottom of the chamber and exposed to the aerosol for 3 h with and without the ionizer treatment. The plates were thenremoved from the chamber, incubated at 37 degrees C for 24 h, and colonies were counted. An average of greater than 10(3) CFU/plate were observed on plates exposed to the aerosol without the ionizer treatment (control) comparedwith an average of less than 53 CFU/plate on the ionizertreated plates. In another series of experiments, the SE aerosol was pumped for 3 h into an empty chamber containing only the ionizer and allowed to collect on the internal surfaces. The inside surfaces of the chamber were then rinsed with 100 ml phosphate-buffered saline that was then plated onto XLT4 plates. While the rinse from the control chamber contained colony counts greater than 400 CFU/ml of wash, no colonies were found in the rinse from the ionizer-treatment chamber. These results indicate that high levels of negative air ions can have a significant impact on the airborne microbial load, and that most of this effect isthrough direct killing of the organisms. This technology, which also causes significant reduction in airborne dust, has already been successfully applied for poultry hatching cabinets and caged layer rooms. Other potential applicationsinclude any enclosed space such as food processing areas, medical institutions, the workplace, and the home, where reduction of airborne and surface pathogens is desired. PMID: 11198431 [PubMed - indexed for MEDLINE]Nerve Damage Research StudiesPEER-REVIEWED SCIENTIFIC STUDYhttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESThis controlled study found that exposure to pulsed electromagnetic fields enhanced the speed and degree of peripheral nerve regeneration twofold in rats with experimentally severed sciatic nerves.215 Results of this controlled study demonstrated that treatment with 15 minutes per day of pulsed electromagneticfields enhanced recovery time of experimentally-injured nerves in rats.216 Results of this study indicated that the use of pulsed electromagnetic fields on experimentally divided and sutured nerves in rats sped up regeneration of damaged nerves and the time it took for limb use to be recovered.219 This study examined the effects of a Soviet Polyus-1 low-frequency magnetotherapy device used to administer approximately 10 mT for approximately 10 minutes in patients with optic nerve atrophy. Patients underwent 10- 15 sessions per course. Results showed that vision acuity in patients with low acuity values (below 0.04 diopters) improved in 50 percent of cases. It was also found that the treatment improved ocular blood flow in cases of optic nerve atrophy. Optimal benefits were experienced after 10 therapy sessions.220

REFERENCES215. H. Ito & C.A. Bassett, "Effect of Weak, Pulsing Electromagnetic Fields on Neural Regeneration in the Rat," Clin Orthop, (181), December 1983, p. 283-290.216. A.R. Raji & R.E. Bowden, "Effects of High-peak Pulsed Electromagnetic Field on the Degeneration and Regeneration of the Common Peroneal Nerve in Rats," Journal of Bone Joint Surg, 65(4), August 1983, p. 478-492.219. A.M. Raji, "An Experimental Study of the Effects of Pulsed Electromagnetic Field (Diapulse) on Nerve Repair," Journal of Hand Surg, 9(2), June 1984, p. 105-112.220. L.V. Zobina, et al., "Effectiveness of Magnetotherapy in Optic Nerve Atrophy. A Preliminary Study," Vestn Oftalmol, 106(5), September-October 1990, p. 54-57.

Neurological Disorders Research StudiesPEER-REVIEWED SCIENTIFIC STUDYhttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESThis article summarizes clinical results obtained the authors in using pulsed electromagnetic fields (Gyuling- Bordacs device) in the treatment of neurological and locomotor disorders among a group of 148 patients in a hospital setting over a period of 3 years. The authors claim that 58-80 percent of such patients experienced benefits of some kind over the course of magnetotherapy.221 This study examined the effects of magnetotherapy on patients suffering from nervous system diseases. Treatment consisted of 10-12 6-minute exposures (10-20 kG, 0.1-0.6 Hz). Results indicated beneficial effects in 25 of the 27 patients receiving the treatment.222 Results of this study found that the use of magnetic fields (30-35 mT, 10 and 100 Hz) produced beneficialeffects in 93 percent of patients suffering from nerve problems.223 REFERENCES221. G. Terlaki, "Clinical Experiences Magnetotherapy," Hungarian Symposium on Magnetotherapy, 2n Symposium, 16-17 May 1987, Szekesfehervar, Hungary, p. 175-179.222. A.A. Skorometz, et al., "Magnetic Impulse Therapy of Patients with Spondylogenic Diseases of the Nervous System," Fizicheskaia Meditzina, 3(1-2), 1993, p. 41-43.

223. A.G. Shiman, et al., "Use of Combined Methods of Magnetoelectrotherapy in the Treatment for Polineuropathies," Vopr Kurortol Fizioter Lech Fiz Kult, (5), 1993, p, 38-41.Osteoarthritis Research StudiesFrom: http://www.tnp.com/encyclopedia/therapy/1/5/Three double-blind placebo-controlled studies enrolling a total about 350 individuals suggest that pulsed electromagnetic field therapy can improve symptoms of osteoarthritis. In one of these studies, 27 individuals with osteoarthritis (mostly of the knee) found that pulsed electromagnetic field therapy could improve pain and mobility.11 Participants received 18 half-hour sessions of PEMF over the course of a month, from a specially designed noncontact air-coil device. The control group received treatment with a sham device. According to several criteria, treated participants experienced statistically significant improvement as compared to the placebo group, had less pain, and showed improved functional performance of the affected areas. No side effects were observed. Another study conducted by the same team the following year found similar results in 86 individuals with osteoarthritis of the knee and 81 with osteoarthritis of the cervical spine.12 Receiving the same 18 half-hour sessions with either the PEMF or sham device, the treated participants with OA of the knee averaged a 29 to 36% improvement in pain and mobility by the end of treatment, while the placebo group averaged 11 to 19% improvement. In the group suffering from OA of the spine, improvement in the treatment group averaged 30 to 35% at the end of treatment, again superior to placebo. For both OA conditions, benefits lasted for at least a month after treatment was stopped. A more recent double-blind trial evaluated low power, extremely low frequency pulsed electromagnetic fields for the treatment ofknee osteoarthritis.39 A total of 176 individuals received 8 sessions of either sham or real treatment over a period of 2 weeks. The results showed significantly greater pain reduction in the treated group.----------------------------------------------------------------------------------From: http://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIES (PEER-REVIEWED SCIENTIFIC STUDIES)Results of this double-blind, placebo-controlled study indicated that exposure to pulsed electromagnetic fields had beneficial effects in the treatment of patients suffering from painful osteoarthritis of the knee or cervical spine. PEMF therapy consisted of 18 exposures lasting 30 minutes and administered 3-5 times per week. 224 This double-blind, placebo-controlled study indicated that treatment with pulsed electromagnetic fields produced significant favorable effects in patients suffering from osteoarthritis.226 This double-blind, placebo-controlled study showed that treatment with pulsed electromagnetic fields

yielded significant benefits in patients suffering from osteoarthritis of the knee or cervical spine. PEMF therapy (25 G, 5-24 Hz) consisted of 18 30-minuteexposures over a period of 3-4 weeks.227 This controlled study examined the effects of changeable magnetic fields (Polus-101 device) coupled with more conventional therapies in the treatment of patients suffering from osteoarthrosis. Magnetic therapy consisted of daily 20 minute exposures for a total of 12 sessions. Results showed more rapid improvements of immunological indices and alleviation of symptoms associated with the disease among patients receiving the combination therapy compared to those treated only conventionally.228REFERENCES224. D.H. Trock, et al., "The Effect of Pulsed Electromagnetic Fields in the Treatment of Osteoarthritis of the Knee and Cervical Spine. Report of Randomized, Double Blind, Placebo Controlled Trials," Journal of Rheumatology, 21(10), 1994, p. 1903-1911.226. D.H. Trock, et al., "Treatment of Osteoarthritis with Pulsed Electromagnetic Fields," Bioelectric Repair and Growth Society, Vol.XIII, 13th Annual Meeting, 10-13 October 1993, Dana Point, CA, p. 14.227. A.J. Bollet, et al., "Treatment of Osteoarthritis with Pulsed Electromagnetic Fields," European Bioelectromagnetics Association, 2nd Congress, 9-11 December 1993, Bled Slovenia, p. 46.228. L. Yurkiv, et al., "The Use of Changeable Magnetic Field in Treatment of Osteoarthrosis," European Bioelectromagnetics Association, 3rd International Congress, 29 February-3 March 1996, Nancy France.The Journal of Rheumatologyhttp://www.jrheum.com/abstracts/abstracts02/1708.htmlCetylated Fatty Acids Improve Knee Function in Patients with OsteoarthritisROBERT HESSLINK Jr, DAVID ARMSTRONG III, M.V. NAGENDRAN, SRINAN SREEVATSAN, and RAJ BARATHUR ABSTRACT.Objective. To determine the benefit of cetylated fatty acids (CFA) on knee range of motion and function in patients with osteoarthritis (OA). Methods. Sixty-four patients with chronic knee OA were evaluated at baseline and at 30 and 68 days after consuming either placebo (vegetable oil; n = 31) or CFA (CeladrinTM; n = 33). Evaluations included physician assessment, knee range of motion with goniometry, and the Lequesne Algofunc tional Index (LAI).Results. After 68 days, patients treated with CFA exhibited significant (p < 0.001) increase in knee flexion (10.1°) compared to patients given placebo (1.1°). Neither group reported improvement in knee extension. Patient responses to the LAI indicated a significant (p < 0.001) shift towards functional improvement for the CFA group (-5.4 points) after 68 days compared to a modest improvement in the placebo group (-2.1 points). Conclusion. Compared

to placebo, CFA provides an improvement in knee range of motion and overall function in patients with OA of the knee. CFA may be an alternative to the use of nonsteroidal antiinflammatory drugs for the treatment of OA. (J Rheumatol 2002;29:1708-12)Key Indexing Terms:FATTY ACIDSFISH OILSOSTEOARTHRITISCETYL MYRISTOLEATE5-LIPOXYGENASEFrom Hesslink Ventures and ClinCyte, San Diego, California, USA, and the Medical Center, Manipal, India. Supported in part by a research contract awarded to ClinCyte by Imagenetix, Inc., San Diego, CA, USA. R. Hesslink Jr, ScD; D. Armstrong III, PhD, Hesslink Ventures; M.V. Nagendran, MD, Medical Center, Manipal; S. Sreevatsan, PhD; R. Barathur, PhD, ClinCyte.Address reprint requests to Dr. R. Hesslink Jr, PO Box 501691, San Diego, CA 92150.Submitted July 27, 2001; revision accepted February 14, 2002.Osteoporosis Research StudiesPEER-REVIEWED SCIENTIFIC STUDIEShttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESThis study examined the effects of pulsed electromagnetic fields on postmenopausal osteoporosis in 10-monthold female rats. Results showed that EMF treatment for one hour per day for 4 months with a 30-gauss maximum pulse reduced bone mass loss to within 10 percent, while a 70-gauss maximum pulse reduced bone mass loss entirely.232 This study examined the effects of long-term pulsing electromagnetic fields in the form of repetitive pulse burstwaves over a period of 6 months in osteoporotic rats. Results showed increased bone volume and formation activity.234 This study examined the effects of a 72-Hz pulsating electromagnetic field administered for 10 hours per day over a period of 12 weeks on bone density in women prone to osteoporosis. Results found significant increases in bone mineral density in the area of EMF exposure.235 In this study, osteoporosis patients received treatment with pulsed electromagnetic fields (50 G, 50-100 Hz) for 30 minutes per session over a period of two years involving 20 sessions. These subjects were compared to similar patients treated with calcitonin. Results indicated PEMF to be effective in reducing pain, and to be even more so when combined with the conventional drug treatment.236 This controlled study examined the effects of pulsed electromagnetic fields in women suffering from postmenopausal osteoporosis. Treatment consisted of daily 30-minute exposures for 20 days every six months.

Results showed that PEMF treatment combined with 100 IU per day of nasal spray synthetic salmon calcitonin arrested bone decrease and significantly increased bone mass relative to patients receiving drug therapy alone.237 Results of this study found the use of total-body low-frequency magnetic fields (60 G, 50-100 Hz) to be effective in the treatment of patients suffering from osteoporosis-related symptoms. Treatment consisted of a total of 15 exposures of 30 minutes each.238232. A. Zati, et al., "Effects of Pulsed Magnetic Fields in the Therapy of Osteoporosis Induced Ovariectomy in the Rat," Boll Soc Ital Biol Sper, 69(7-8), July-August 1993, p. 469-475.233. C.T. Rubin, et al., "Prevention of Osteoporosis Pulsed Electromagnetic Fields," Journal of Bone Joint Surg, 71(3), March 1989, p. 411-417.234. S. Mishima, "The Effect of Long-term Pulsing Electromagnetic Field Stimulation on Experimental Osteoporosis of Rats," Sangyo Ika Daigaku Zasshi, 10(1), March 1, 1988, p. 31-45.235. F. Tabrah, et al., "Bone Density Changes in Osteoporosis-prone Women Exposed to PulsedElectromagnetic Fields (PEMFs)," Journal of Bone Miner Res, 5(5), May 1990, p. 437-442.236. T.W. Bilotta, et al., "The Use of Low-Frequency Low Magnitude PEMFs in Treatment of Osteoporosis," Journal of Bioelectr, 8(2), 1989, p. 316.237. T.W. Bilotta, et al., "Influence of Pulsed Electromagnetic Fields on Post-Menopausal Osteoporosis," First World Congress for Electricity and Magnetism in Biology and Medicine, 14-19 June 1992, Lake Buena Vista, FL, p. 78.238. G. Saveriano & S. Ricci, "Treatment of Senile Osteoporosis Caused Rachialgia with Low-Frequency PEMFs," Journal of Bioelectr, 8(2), 1989, p.21.Pancreatitis Research Studyhttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESThis study found that sinusoidal and continuous low-frequency alternating magnetic field generated a Polius-1 apparatus exhibited beneficial effects in patients suffering from chronic pancreatitis.241 This controlled study examined the effects of combining pulsed electric stimulation and laser light with conventional treatment in patients suffering from acute pancreatitis. Results showed the combined therapy to have the most significant effects in patients with severe forms of the disease.242References241. A.A. Fedorov, et al., "The Use of a Low-frequency Magnetic Field in the Combined Therapy of Chronic Pancreatitis," Vopr

Kurortol Fizioter Lech Fiz Kult, (5), September-October 1990, p. 28-30.242. O.G. Savina, et al., "A Low-Frequency Pulsed Current and a Low-Intensity Laser Radiation in the Treatment of Acute Pancreatitis," Vopr Kurortol Fizioter Lech Fiz Kult, (2), 1995, p. 39-40.Parkinson’s Research Studieshttp://www.cogreslab.demon.co.uk/Magnetsmed.htmSandyk of the University of Thrace, Greece, has presented numerous papers in a peer-reviewed journal (Intl. J. Neuroscience) reporting individual cases of successful Parkinson’s and MS treatment by means of picoTesla alternating fields (Sandyk, 1993; 1994). He suggests that these fields influence the pineal gland and inhibit the secretion of melatonin, thereby reducing hyperglycaemia.. Admittedly these are not static, but their flux density is much lower than the earth’s half a gauss geomagnetic field, which continually oscillates around a 20nanoTesla variation. One might even argue that such minute oscillations are indispensable for cellular processes in living creatures, though their mechanism of interaction is not understood: it is said that astronauts are now routinely supplied with an artificial earth’s field during space flights following severe mental problems arising in its absence. Surprisingly little research has followed up Sandyk’s remarkable findings, though the present NASA space program is investigating performance in aged subjects, which completes the connection with Parkinson’s and Alzheimer’s, both being diseases of age.Other Parkinson’s Research StudiesPEER-REVIEWED SCIENTIFIC STUDYhttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESThis article reports on the case of a 73-year-old male Parkinson's patients suffering from disabling resting and postural tremors in the right hand, as well as other symptoms. Two successive 20-minute treatments with AC pulsed electromagnetic fields of 7.5-picotesla intensity and 5-Hz frequency sinusoidal wave led to improvements in visuospatial performance and a legible signature. Significant improvements in Parkinsonian motor symptoms were also seen following additional treatments.243 This article reports on the case of a medicated 61-year-old Parkinson's patient who experienced rapid reversal of symptoms following a single external application of picotesla-range magnetic fields.244 This article reports on four Parkinson's patients who experienced significant improvement in symptoms following treatment with picotesla-range magnetic fields. Two additional patients suffering from Parkinson's-related dementia experienced significant improvements in visuospatial impairment.245Noting that transcranial magnetic stimulation (TMS) is a new and noninvasive method of direct cortical neuron stimulation, this review article discusses recent studies showing that TMS has led to improvements in symptoms associated

with Parkinson's disease and depression.246 Results of this study showed that the application of ELF magnetic fields via a plastic helmet device housing a set of coils (generating fields of 8 Hz and 7.5 pT) produced beneficial clinical effects after 30 minutes in patients suffering Parkinson's disease and multiplesclerosis.247 This article reports on the cases of two Parkinson's patients who experienced improvements in motor symptoms following treatment with external application of weak electromagnetic fields in the picotesla range.248This article reports on the cases of three Parkinson's patients on full medication who exhibited an improvement in right hemispheric functions following a series of treatments with external application of electromagnetic fields in the picotesla range.249 This article reports on the case of a nonmedicated 49-year-old male Parkinson's patient who experienced a dramatic improvement in motor, depressive, and cognitive symptoms following treatment with brief extracranial applications of picotesla-range electromagnetic fields.251 This article reports on the case of a 61-year-old Parkinson's patient who experienced improvements in the severity of motor problems 30 minutes after treatment with external application of weak electromagnetic fields in the picotesla range. Sham treatment had no such effects in the same patient.252 This article reports on the cases of five Parkinsonian patients on full medication who experienced a marked improvement in performance on Thurstone's Word-Fluency Test following treatment with a series of extremely-low-intensity electromagnetic fields in the picotesla range and of 5-8 Hz frequency.253 This article reports on the case of a 69-year-old Parkinsonian patient who was able to discontinue most medication for two weeks following two treatment sessions with extracranial picotesla-range magnetic fields. Symptoms recurred after three weeks and the patient received four more magnetic field sessions on consecutive days after four weeks. The patient was then able to discontinue medications completely.254 This article reports on the cases of five medicated Parkinsonian patients who experienced improvements in motor, behavioral, and autonomic functions, and in visuoconstructional tasks following treatment with extracranial application of magnetic fields in the picotesla range.255 This article reports on the cases of three medicated Parkinsonian patients who experienced relief from disabling periods of freezing gait following treatment with extracerebral applications of pulsed electromagnetic fields in the picotesla range.256 The cases of four nondemented Parkinsonian patients under full medication are discussed in this article. These patients performed poorly on human figure drawing tests administered to measure body image perception. Treatment with extracerebral applications of picoteslarange intensity electromagnetic fields led to marked improvements in body image perception as seen on a repeat of the same test each patient.257

This article reports on the cases of four medicated Parkinsonian patients who experienced reversal of visuospatial impairments as measured the Clock Drawing Test following treatment with externally applied weak electromagnetic fields of picotesla-range intensity.258This article reports on the case of a 68-year-old male patient suffering from Parkinson's disease over a period of 7 years. The patient had experienced little relief from traditional medical therapy. Treatment with external application of picotesla-range magnetic fields led to quick improvements with respect to tremor and foot dystonia, gait, postural reflexes, mood, anxiety, and cognitive and autonomic functions.259 This article reports on the cases of four Parkinsonian patients who exhibited significant improvements in motor symptoms following treatment with externally applied magnetic fields of picotesla-range intensity.260 This article reports on two cases of fully medicated Parkinson's patients who experienced enhanced visuoperceptive functions as measured numerous drawing tests following extracranial treatment with picotesla-range magnetic fields.261 This article reports on the case of a 69-year-old Parkinsonian patient on full medication who experienced a marked improvement on several different drawing tests following 30 minutes of treatment with picotesla-range magnetic fields.262 This article reports on the case of a Parkinson's patient suffering from severe movement problems who received treatment with external artificial weak magnetic fields with a frequency of 2 Hz and intensity of 7.5 picotesla over a period of 6 minutes. Results showed a significant attenuation in disability and near total reversal of the symptoms lasting approximately 72 hours. The patient then applied equivalent magnetic fields on a daily basis at home. Sustained improvement was seen throughout an observation of one month.263 This article reports on the case of a 67-year-old male patient suffering from Parkinson's disease and levodopa-related motor fluctuations. Treatment with the application of external weak magnetic fields led to improvements in general Parkinsonian symptoms along with the amelioration of "on-off" symptoms.264REFERENCES243. R. Sandyk, "Brief Communication: Electromagnetic Fields Improve Visuospatial Performance and Reverse Agraphia in a Parkinsonian Patient," International Journal of Neurosci, 87(3-4), November 1996, p. 209-217.244. R. Sandyk & R.P. Iacono, "Reversal of Visual Neglect in Parkinson's Disease Treatment with picoTesla Range Magnetic Fields," International Journal of Neurosci, 73(1-2), November 1993, p. 93-107.245. R. Sandyk, "Magnetic Fields in the Therapy of Parkinsonism," International Journal of Neurosci, 66(3-4), October 1992, p. 209-235.

246. M.S. George, et al., "Transcranial Magnetic Stimulation: A Neuropsychiatric Tool for the 21st Century," Journal of Neuropsychiatry Clin Neurosci, 8(4), Fall 1996, p. 373-382.247. J. Bardasano, et al., "Extracranial Device for Noninvasive Neurological Treatments with Pulsating ELF Magnetic Fields," Second World Congress for Electricity and Magnetism in Biology and Medicine, 8-13 June 1997, Bologna, Italy.248. R. Sandyk, "Parkinsonian Micrographia Reversed Treatment with Weak Electromagnetic Fields," International Journal of Neurosci, 81(1-2), March 1995, p. 83-93.249. R. Sandyk, "Improvement in Short-term Visual Memory Weak Electromagnetic Fields in Parkinson's Disease," International Journalof Neurosci, 81(1-2), March 1995, p. 67-82.250. R. Sandyk, "Weak Electromagnetic Fields Reverse Visuospatial Hemi-inattention in Parkinson's Disease," International Journal of Neurosci, 81(1-2), March 1995, p. 47-65.251. R. Sandyk, "A Drug Naive Parkinsonian Patient Successfully Treated with Weak Electromagnetic Fields," International Journal of Neurosci, 79(1-2), November 1994, p. 99-110.252. R. Sandyk & R.P. Iacono, "Reversal of Micrographia in Parkinson's Disease Application of picoTesla Range Magnetic Fields," International Journal of Neurosci 77(1-2), July 1994, p. 77-84.253. R. Sandyk, "Improvement in Word-fluency Performance in Parkinson's Disease Administration of Electromagnetic Fields," International Journal of Neurosci, 77(1-2), July 1994, p. 23-46.254. R. Sandyk, "Treatment of Parkinson's Disease with Magnetic Fields Reduces the Requirement for Antiparkinsonian Medications, International Journal of Neurosci, 74(1-4), January-February 1994, p. 191-201.255. R. Sandyk, "Reversal of a Visuoconstructional Deficit in Parkinson's Disease Application of External Magnetic Fields: A Report of Five Cases," International Journal of Neurosci, 75(3-4), April 1994, p. 213-228.256. R. Sandyk, "Freezing of Gait in Parkinson's Disease is Improved Treatment with Weak Electromagnetic Fields," International Journal of Neurosci, 85(1-2), March 1996, p. 111-124.257. R. Sandyk, "Improvement of Body Image Perception in Parkinson's Disease Treatment with Weak Electromagnetic Fields," International Journal of Neurosci, 82(3-4), June 1995, p. 269-283.258. R. Sandyk, "Reversal of Visuospatial Deficit on the Clock Drawing Test in Parkinson's Disease Treatment with Weak Electromagnetic Fields," International Journal of Neurosci, 82(3-4), June 1995, p. 255-268.

259. R. Sandyk & K. Derpapas, "The Effects of External picoTesla Range Magnetic Fields on the EEG in Parkinson's Disease," International Journal of Neurosci, 70(1-2), May 1993, p. 85-96.260. R. Sandyk & K. Derpapas, "Further Observations on the Unique Efficacy of PicoTesla Range Magnetic Fields in Parkinson's Disease," International Journal of Neurosci, 69(1-4), March-April 1993, p. 67-83.261. R. Sandyk & R.P. Iacono, "Rapid Improvement of Visuoperceptive Functions picoTesla Range Magnetic Fields in Patients with Parkinson's Disease," International Journal of Neurosci, 70(3-4), June 1993, p. 233-254.262. R. Sandyk, "The Effects of PicoTesla Range Magnetic Fields on Perceptual Organization and Visual Memory in Parkinsonism," International Journal of Neurosci, 73(3-4), December 1993, p. 207-219.263. R. Sandyk, et al., "Magnetic Fields in the Treatment of Parkinson's Disease," International Journal of Neurosci, 63(1-2), March 1992, p. 141-150.264. R. Sandyk, "Weak Magnetic Fields in the Treatment of Parkinson's Disease with the "On-off" Phenomenon," International Journal o Neurosci, 66(1-2), September 1992, p. 97-106.

Pneumonia Research Studieshttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESResults of this study showed that magnetic laser therapy decreased the severity of acute respiratory insufficiency and treatment course, and prevented destructive complications in children with infiltrative acute destructive pneumonia between the ages of 1 and 12 years.266References266. E.A. Gaidashev, et al., "An Evaluation of the Effect of Magnetic-laser Therapy on External Respiratory Function in Complicated Forms of Acute Pneumonia in Children," Vopr Kurortol Fizioter Lech Fiz Kult, (3), May-June 1995, p. 12-14.Post PolioFrom: http://www.tnp.com/encyclopedia/therapy/1/5/A double-blind placebo-controlled study of 50 individuals with post-polio syndrome found evidence that magnets are effective for relieving pain.2 The magnets were placed on previously determined trigger points (one per person) for 45 minutes. (Trigger points are sore areas within muscle that, when pressed, cause relief in other areas of the muscle, and conversely, when inflamed, cause pain in other parts of the muscle.) In the treatment group, 76% of the participants reported improvement, compared to 19% in the placebo group.

------------------------------------------------------------------------From: http://www.archives-pmr.org/abs78_11/v78n11p1200.htmlA 1997 study published in the Archives of Physical Medicine and Rehabilitation looked at 50 patients with post-polio pain. The research by Dr. Carlos Vallbona, a professor at Baylor University College of Medicine in Texas, found that of 29 patients who wore magnets, 76 percent reported a decrease in pain after 45 minutes. Those who got placebos reported only slight improvement. Another study was performed examining the effect of bipolar magnets on post-polio syndrome, a condition characterized by muscle tenderness and pain in patients who have had polio. The condition occurs years after the original damage from the polio virus. Application of magnets to these tender, painful spots was shown to alleviate pain in this double-blind placebo-controlled study, the results of which were published in the November 1997 issue of the "Archives of Physical Medicine and Rehabilitation". Psychiatric Disorders Research Studieshttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESNoting the well-established dangers associated with electroconvulsive therapy, the author, in this theoretical article, argues that transcranial magnetic stimulation should be looked at as an alternative psychiatric treatment. The author asserts that TMS has several advantages over ECT in that it is painless, noninvasive, and more effective on deep structures of the brain.277References277. T. Zyss, "Deep Magnetic Brain Stimulation - The End of Psychiatric Electroshock Therapy?" Medical Hypotheses, 43(2), 1994, p. 69-74.Schizophrenics Research Studyhttp://www.foxnews.com:80/health/032400/brain.smlIn a research letter published in the Lancet Medical Journal in March of 2000, scientists at Yale University in Connecticut, said Schizophrenic sufferers they had studied reported fewer hallucinations after brain stimulation. 12 schizophrenics who had daily hallucinations were divided into two groups. In all but one case, hallucination severity was lower after the active stimulation sequence. Schizophrenia is the most common form of severe mental illnessReconstructive Surgeryhttp://www.charlotte.com/observer/0207magnetstudy.htmBy JANE E. ALLENLos Angeles TimesResearch published in the December issue of the Journal of Plastic and Reconstructive Surgery studied 20 patients recuperating from liposuction of excess body fat, or "love handles." In the research by Dr. Daniel Man, a board-certified plastic surgeon in Boca Raton, Fla., 10 patients wore magnetic pads on

their wounds; 10 others had sham magnets in the pads Those who got the magnetic pads had less pain in the first week, less swelling in the first four days and less black-and-blue discoloration in the first three days than did the control group.Respiratory Problems Research Studieshttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESResults of this study showed that the use of low-frequency magnetic fields helped to prevent and treat critically ill patients suffering from pyoinflammatory bronchopulmonary complications, and to prevent such complications as well.278 This article reports on the case of a schizophrenic patient suffering from respiratory difficulties associated with neuroleptic withdrawal. Treatment using external application of picotesla-range magnetic fields quickly attenuated the severity of such problems.279References278. G.A. Mozhaev & IIu Tikhonovskii, "The Prevention and Treatment of Suppurative-inflammatory Complications in the Bronchopulmonary System During Prolonged Artificial Ventilation," Anesteziol Reanimatol, (4), July-August 1002, p. 47-51. 279. R. Sandyk & K. Derpapas, "Successful Treatment of Respiratory Dyskinesia with picoTesla Range Magnetic Fields,"International Journal of Neurosci, 75(1-2), March 1994, p. 91-102.Rheumatism Research StudiesA double-blind controlled trial of 64 individuals with rheumatoid arthritis of the knee compared the effects of strong alternating polarity magnets (See How to Use Magnet Therapy for definition) with a deliberately weak unipolar magnet.36 Researchers used the weakened magnet as a control group so that participants wouldn’t find it easy to break the blind by testing the magnetism of their treatment. Patients were assessed daily for one week. After one week of therapy, 68% of the participants using the strong magnets (the "treatmentgroup") reported relief, as compared to 27% in the control group, and this difference was statistically significant. Four other measurements of symptom severity showed greater benefits in the treatment group than in the control group, but in only two of these were the differences statistically significant. Treatment did not alter results of blood tests for inflammation severity, nor did it change physician’s assessment of joint tenderness, swelling or range of motion. This study suggests that magnet therapy may reduce the pain of rheumatoid arthritis without altering actual inflammation. However, the mixture of statistically significant and insignificant results indicates that a larger trial is necessary to factor out "statistical noise."From: http://www.tnp.com/encyclopedia/therapy/1/5/------------------------------------------------------------------------------------------------

From: http://www.cogreslab.demon.co.uk/Magnetsmed.htmThe disease is believed to be caused by an infection that prompts the immune system to form damaging aggregates of antigen and antibody. Treatment is confined to control of inflammation and the relief of pain by bedrest, splintage, physiotherapy, and antiinflammatory or pain killing drugs. Several studies on this disorder report beneficial effects with pulsed magnetic fields in combination with conventional management (Kocian et al., 1985a, 1985b; Jezek, 1990). In a large study of cervical osteochondritis Detlavs (1987) applied static magnetic fields (100-400 gauss, 15-20 minutes duration, 10-20 treatments) to 425 patients, of whom 138 were male. The results were a significant improvement in arterial tonus and venous tonation as measured by rheography, in some patients after 3-6 exposures and in all by the end of treatment. An earlier study on patients with rheumatoid arthritis (Aryshenskaya, 1977) used a static magnetic field (150-350 gauss, 10 minutes, 10-20 exposures) reported that patients in stages 1 and 2 responded well, not only clinically, but also as measured by laboratory parameters such as % albumin, gamma globulin and fibrinogen (gm/l). In gamma globulins a decrease of 24% was observed.

Schizophreniahttp://www.foxnews.com:80/health/032400/brain.smlIn a research letter published in the Lancet Medical Journal in March of 2000, scientists at Yale University in Connecticut, said Schizophrenic sufferers they had studied reported fewer hallucinations after brain stimulation. 12 schizophrenics who had daily hallucinations were divided into two groups. In all but one case, hallucination severity was lower after the active stimulation sequence. Schizophrenia is the most common form of severe mental illness--------------------------------------------------------------------Magnet Therapy Helps Schizophrenics:http://www.mercola.com/2000/mar/26/magnet_schizophrenia.htmUsing magnets to stimulate a particular area of the brain appears to help auditory hallucinations experienced by patients with schizophrenia. About 50% to 70% of patients with schizophrenia report having auditory hallucinations, often in the form of imaginary voices. Drugs offer little help, and these hallucinations can cause distress, disability, and leave patients unable to control their behavior. The investigators applied a lowfrequency magnetic field to the left temporoparietal cortex of each patient for 4 minutes the first day, whichincreased by 4 minutes each day to 16 minutes on day 4. For comparison purposes, each patient also went through a "sham" stimulation, where patients had similar treatment but did not receive a magnetic field. The treatment was

well tolerated, and there was significant improvement in the hallucination severity after 12 and 16 minutes of active stimulation. The severity of hallucinations was reduced in all but one patient. However, in the 8 patients classified as responders, the hallucinations returned after a period ranging from 4 days to 2 months after the treatment.The Lancet March 25, 2000;355:1073-1075.COMMENT: Energy medicine is clearly the medicine of the future. It is great to see that some of these novel techniques are being validated in respectable good journals.Seizure Research Studieshttp://www.pslgroup.com/dg/16596e.htmBOCA RATON, FL -- February 17, 2000 -- Jacobson Resonance Enterprises, Inc. reported the results of a double blind, pilot clinical study in epilepsy conducted at the University of Oklahoma Health Sciences Center by principal investigator Kalarickal Oommen, M.D., director of epilepsy research and nationally recognized authority in the treatment and research of epilepsy seizures. The data indicated that treatment with the Jacobson Resonator, utilizing low-intensity and low-frequency magnetic fields, decreased seizure frequency in some patients with intractable partial complex epilepsy significantly and that this modality may be a useful adjunctive treatment in these patients and others. Intractable partial complex epilepsy patients were enrolled in a pilot medical study in a non-randomized and double blind fashion. In the first phase of seven weeks, each patient received either magnetic treatment or no treatment for 40 minutes per treatment per week. In the second phase of seven weeks, the order was reversed for patients receiving no treatment or magnetic field treatment. It was found that 66 percent of the patients had a mean decrease in seizure frequency of 33 percent plus during the study.Dr. Kalarickal Oommen stated, "The results are very encouraging when you compare it to the way anti-epileptic drugs (AEDs) are approved by the FDA. The percentages for some of the recently marketed AEDs and the Vagus Nerve Stimulator were in the 17-25 percent range or under. I believe this is great news, particularly when you consider that patients were only treated once a week and noninvasively." Dr. Jerry Jacobson, Chairman and CEO, stated, "The follow-up study will be double blinded and contain a greater population of patients who will be treated three times per week instead of only once a week. We are hopeful that the seizure reduction level will thus rise to 50 percent. We are moving quickly with I.R.B. approval for our next phase of the clinical trial and hope to request to the FDA 'expedited review' for approval next year.Other Research Studieshttp://www.garynull.com/Documents/magnets.htm#121

This article reports on the cases of three patients with partial seizures who received treatment with external artificial magnetic fields of low intensity. Such treatment led to a significant attenuation of seizure frequency over a 10-14-month period.121 Experimental results indicated that the administration of modulated electromagnetic fields of 2-30 Hz suppressed epilepsy in rats.122This review article cites one study in particular in which results showed that pretreatment with 30 minutes of exposure to a 75-mT pole strength, DC-powered magnetic field significantly prevented experimentally induced seizures in mice.123 This double-blind, placebo-controlled study examined the effects of 2-hour exposure to weak magnetic fields (0.2-0.7 G, irregularly oscillating 0.026-0.067 Hz) produced 3 pairs of orthogonal Helmholtz coils on pain perception in healthy subjects. Results showed that magnetic treatment significantly reduced the perception of pain.124 This article reports on the case of a severe epileptic who experienced a significant lessening of behavior disturbances and seizure frequency following treatment with low-frequency, external artificial magnetic fields.125 Low-frequency, external artificial magnetic field treatment was shown to significantly reduce seizures in four adult epileptic cases.126References121. P.A. Anninos, et al., "Magnetic Stimulation in the Treatment of Partial Seizures," International Journal of Neurosci, 60(3-4), October 1991, p. 141-171.122. G.D. Antimonii & R.A. Salamov, "Action of a Modulated Electromagnetic Field on Experimentally Induced Epileptiform Brain Activity in Rats," Biull Eksp Biol Med, 89(2), February 1980, p. 145-148.123. M.J. McLean, et al., "Therapeutic Efficacy of a Static Magnetic Device in Three Animal Seizure Models: Summary of Experience," Second World Congress for Electricity and Magnetism in Biology and Medicine, 8-13 June 1997, Bologna, Italy.124. F. Sartucci, et al., "Human Exposure to Oscillating Magnetic Fields Produces Changes in Pain Perception and Pain-Related Somatosensory Evoked Potentials," Second World Congress for Electricity and Magnetism in Biology and Medicine, 8-13 June 1997, Bologna, Italy.125. R. Sandyk & P.A. Anninos, "Attenuation of Epilepsy with Application of External Magnetic Fields: A Case Report," International Journal of Neurosci, 66(1-2), September 1992, p. 75-85.126. R. Sandyk & P.A. Anninos, "Magnetic Fields Alter the Circadian Periodicity of Seizures," International Journal of Neurosci, 63(3-4), April 1992, p. 265-274.Sexual Disorders Research Studieshttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIES

Results of this placebo-controlled study showed that magnetotherapy exhibited beneficial effects with respect to cavernous blood flow in male patients suffering from sexual problems.280 This study examined the effects of a combination pulsing magnetic field (PMF)/vacuum therapy in the treatment of impotence. Vacuum therapy consisted of the penis being placed into a hermetic cylinder with a negative pressure of 180-260 mmHg for 10-12 minutes per exposure for a total of 12-15 exposures. PMF therapy consisted of the same length and number of exposures, with 6 Hz, 30 mT being applied to the penile area at the same time as vacuum therapy. Results showed that, following the combination therapy, sexual function was restored in about 71 percent of patients, was improved in 17 percent, and did not change in 17 percent. For those patients receiving vacuum therapy only, the numbers were 51, 24, and 24 percent, respectively.281 This double-blind, placebo-controlled study examined the effects of weak magnetic fields in men suffering from various sexual disorders, including decreased erection and premature ejaculation. The three different magnetic stimulators used included the "Biopotenzor," "Eros," and "Bioskan-1" devices. All patients wore one of the three devices for a 3-week period. Results showed full restoration of sexual function in 38 percent of patients in the Biopotenzor group, 31 percent in the Eros group, 36 percent in the Bioskan-1 group, and in just 15 percent of the controls. Improvements in sexual function were seen among 42 percent, 39 percent, 47 percent, and 18 percent, respectively.282References280. I.I. Gorpinchenko, "The Use of Magnetic Devices in Treating Sexual Disorders in Men," Lik Sprava, (3-4), March-April 1995, p 95-97.281. I.V. Karpukhin & V.A. Bogomol'nii, "Local Vacuum-Magnetotherapy of Impotency Patients," Vopr Kurortol Lech Fiz Kult, (2) 1996, p. 38-40.282. I.I. Gorpinchenko, "The Use of Magnetic Devices in Treating Sexual Disorders in Men," Lik Sprava, (3-4), 1995, p. 95-97.Skin Research Studieshttp://www.cogreslab.demon.co.uk/Magnetsmed.htmSome of our most common ailments today include skin diseases such as psoriasis, psoriatic arthritis, eczema, and pruritis. These all have their origin in immune dysfunction, and fall therefore under immediate suspicion as being "modern" disorders of environmental origin. Among the more remarkable magnetic field studies 50Hz magnetic fields for 28 days achieved complete freedom from symptoms in 30 of 50 sufferers and 15 marked improvements (Tretyakova, 1985). In a study of 16 microbial eczemas, 6 neurodermatitis cases, and 15 crural ulcers, Zaerko in 1988 reported improvement in 13 of the eczema cases following 10 hours exposure to 350 gauss static magnetic fields over 10-20 sessions. 13 of the crural ulcers also improved. Granulation of tissue

was also reported and epithelialisation, as well as decreased oedema in 5 of 7 patients with crural ulcers in a study by Sieron (1989).Sleep Disorders Research Studieshttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESResults of this double-blind, placebo-controlled study indicated that low-energy-emission therapy significantly improved sleeping patterns among patients suffering from chronic psychophysiological insomnia. Therapy was administered 3 times per week, always in late afternoon and for 20 minutes, over a period of 4 weeks.284 This double-blind, placebo-controlled study examined the effects of low-energy emission therapy (27 MHz amplitude-modulated electromagnetic fields) in patients suffering from insomnia. Treatment consisted of 3 exposures per week over a 4-week period. Results showed significant increases in total sleep time among patients in the treatment group relative to controls.285 This review article notes that studies have found low-energy emission therapy to be effective in the treatment of chronic insomnia, and suggests that it may also be of value for patients suffering from generalized anxiety disorders.286References283. T.U. Gorgiladze & B.M. Kogan, "A New Method of Treatment of a Dry Kerato-Conjunctivitis in Sjogren's Syndrome," Oftalmol Zh, (1), 1996, p.38-40.284. R. Hajdukovic, et al., "Effects of Low Energy Emission Therapy (LEET) on Sleep Structure," First World Congress for Electricity and Magnetism in Biology and Medicine, 14-19 June 1992, Lake Buena Vista, FL, p. 92. 285. M. Erman, et al., "Low-Energy Emission Therapy (LEET) Treatment for Insomnia," Bioelectromagnetics Society, 13th Annual Meeting, 23-27 June 1991, Salt Lake City, UT, p. 69. 286. C. Guilleminault & B. Pasche, "Clinical Effects of Low Energy Emission Therapy," Bioelectromagnetics Society, 15th Annual Meeting, 13-17 June 1993, Los Angeles, CA, p. 84.Spinal Cord Injury Research Studieshttp://www.cogreslab.demon.co.uk/Magnetsmed.htmIn a study of 104 patients with spinal cord injuries Tchach, Abileva et al., in 1989 applied 400-700 gauss static magnets for an hour 1 to 3 times daily, and reported marked functional improvement (bedridden: 83.5%; those in chairs 22% compared with only 4% among controls). There was not only a clinical improvement, but the electromyogram (EMG) also improved with magnetic treatment. Another early trial of 11 children with polyradiculoneuritis achieved complete healing in 7 of them using 28-gauss magnets applied in10 sessions of 10-15 minutes (Deyanova, 1976).--------------------------------------------------------Magnetic Treatment and Spinal Cord Injuries

http://www.medicalnewstoday.com/?newsid=8155 - 11 May 2004 A preliminary study has shown for the first time that it may be possible to help people who have suffered partial damage to their spinal cord by applying a magnetic therapy to their brain. Writing in this month's Spinal Cord, a team of UK doctors describe how patients with incomplete spinal cord injuries received repetitive transcranial magnetic stimulation (rTMS), leading to improvements in their ability to move muscles and limbs, and ability to feel sensations. rTMS uses an electromagnet placed on the scalp to generate brief magnetic pulses, about the strength of an MRI scan, which stimulate the part of the brain called the cerebral cortex. Incomplete spinal cord injuries are a type of spinal injury where the spinal cord has not been entirely severed, but the patient has still lost the ability to move or feel properly below the injury point. Dr Nick Davey from Imperial College London and Charing Cross Hospital, and one of the study's authors, says: "Through rTMS we may be able to help people who have suffered partial injuries to the spinal cord recover some of their movement and feeling. We think it works by strengthening the information leaving the brain through the undamaged neurons in the spinal cord. It may work like physiotherapy but instead of repeating a physical task, the machine activates the surviving nerves to strengthen their connections." The researchers from Imperial College London, the National Spinal Injuries Centre, Stoke Mandeville Hospital, UK, and Charing Cross Hospital, UK, tested rTMS on four patients with incomplete spinal injuries. The patients had all sustained their injuries at least 18 months previously and had already received conventional rehabilitation including physiotherapy. They were all considered stable in that they were no longer undergoing natural improvement. The patients received both real and sham rTMS treatment over a three-week period. The rTMS treatment involved five consecutive days of magnetic stimulation for one hour per day. They noticed no difference between the baseline and the sham treatment, but found that the rTMS treatment resulted in a 37.5 (+/– 8) percent drop in intracortical inhibition, compared with normal physiotherapy. Weaker intracortical inhibition makes it easier for messages from the brain to pass down the spinal cord to the rest of the body. This reduction in intracortical inhibition was accompanied by improvement in both motor and sensory function, which lasted for at least three weeks after the treatment. Reduced intracortical inhibition also occurs naturally and can facilitate functional recovery, and this is reflected in improvements to the patients' ability to move and feel. rTMS was a treatment designed to treat psychiatric disorders, and has been used in treating some of the symptoms of schizophrenia. Dr Davey adds: "Despite this, we still need to be extremely careful in interpreting these results as we only sampled a small number of patients. Further studies on larger groups of patients will need to be

carried out before we will know if this treatment is fully effective. Similarly we have no idea how long the treatment benefits will last over a longer period."This work was supported by the International Spinal Research Trust, and Dr Davey and his team have recently received a further grant, again from the International Spinal Research Trust, to carry out further, larger trials.Notes to editors:1. Magnetic brain stimulation can improve clinical outcome in incomplete spinal cord injured patients. Spinal Cord, May 2004. 2. Consistently rated in the top three UK university institutions, Imperial College London is a world leading science-based university whose reputation for excellence in teaching and research attracts students (10,000) and staff (5,000) of the highest international quality. Innovative research at the College explores the interface between science, medicine, engineering and management and delivers practical solutions that enhance the quality of life and the environment - underpinned by a dynamic enterprise culture. Website: www.imperial.ac.uk.Contact: Tony Stephensonat.stephenson@imperial.ac.uk44-207-594-6712Imperial College of Science, Technology and MedicineStroke Research Studieshttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESResults of this study demonstrated that treatment with sinusoidal modulated currents coupled with transcerebral magnetic fields proved more effective than either therapy on its own in the treatment of stroke patients during the period of early rehabilitation.290 This study found that exposure to pulsed electromagnetic fields following focal cerebral ischemia provided significant protection against neuronal damage, in rabbits.291 Results of this study pointed to the efficacy of magnetic field therapy in the treatment of patients suffering from a variety of conditions associated with different brain vascular diseases.292References290. F.E. Gorbunov, et al., "The Effect of Combined Transcerebral Magnetic and Electric Impulse Therapy on the Cerebral and Central Hemodynamic Status of Stroke Patients in the Early Rehabilitation Period," Vopr Kurortol Fizioter Lech Fiz Kult, (3), May-June 1996, p. 21-24.291. G. Grant, et al., "Protection Against Focal Cerebral Ischemia Following Exposure to a Pulsed Electromagnetic Field," Bioelectromagnetics, 15(3), 1994, p. 205-216.292. N.Y. Gilinskaia, "Magnetic Fields in Treatment of Vascular Diseases of the Brain," Magnitologiia, 1, 1991, p. 13-17.

Surgery Research StudiesDouble-blind study published in the December issue of the Journal of Plastic and Reconstructive Surgery studied 20 patients recuperating from liposuction of excess body fat, or "love handles." In the research by Dr. Daniel Man, a board-certified plastic surgeon in Boca Raton, Fla., 10 patients wore magnetic pads on their wounds; 10 others had sham magnets in the pads. Those who got the magnetic pads had less pain in the first week, less first three days than did the control group.Tendonitis Research StudiesPEER-REVIEWED SCIENTIFIC STUDYhttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESResults of this double-blind, placebo-controlled study indicated that pulsed electromagnetic field therapy exhibited significant beneficial effects in the treatment of patients suffering from persistent rotator cuff tendonitis.294 This double-blind, placebo-controlled study examined the effects of a magnetic treatment device taped over the carpal tunnel against wrist pain sustained at work among a group of turkey plant employees. Results showed that the device was effective in alleviating such pain and that it was free of side effects.323REFERENCES294. A. Binder, et al., "Pulsed Electromagnetic Field Therapy of Persistent Rotator Cuff Tendinitis. A Doubleblind Controlled Assessment," Lancet, 1(8379), March 31, 1984, p. 695-698.323. M.J. McLean, et al., "Treatment of Wrist Pain in the Work Place with a Static Magnetic Device – Interim Report of a Clinical Trial," Second World Congress for Electricity and Magnetism in Biology and Medicine, June 8-13, Bologna, Italy.Tourette's SyndromeResearch Studieshttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESThis article reports on the case of a 6-year-old boy suffering from Tourette's syndrome who experienced improvements in visuoconstructional and visuomotor skills, along with more general symptomatic improvements, following the extracranial application of electromagnetic fields in the picotesla range of intensity.295References295. R. Sandyk, "Improvement of Right Hemispheric Functions in a Child with Gilles de la Tourette's Syndrome Weak Electromagnetic Fields," International Journal of Neurosci, 81(3-4), April 1995, p. 199-213.Tuberculosis Research Studies

http://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESThis study examined the efficacy of millimeter waves combined with conventional drug treatment in patients suffering from tuberculosis. MW therapy consisted of 10 exposures of the thymus area for 60 minutes per day using a "Yavor" apparatus (6.4 or 7.1 mm wavelength). Controls received drug treatment only. Results indicated that while MW/drug therapy had no effect on the clearance of the tuberculosis bacteria, it did facilitate clinical recovery faster than drug therapy alone.296 This study examined the effects of extremely-high-frequency therapy as administered via a "Yav'-1-7,1" apparatus (7.1 mm wavelength) on tuberculosis patients. Results showed a 25-percent improvement in patients receiving the therapy as a pathogenic treatment. A 72-percent improvement rate was seen among patients who received the therapy astreatment for concurrent diseases.297 This controlled study examined the effects of constant elastic electromagnetic fields (40mT) in patients suffering from pulmonary tuberculosis. Therapy consisted of 30-45 minute daily application of either a single magnet or a pair of magnets placed on the chest atan area high in skin temperature over a 1-3 month period. When coupled with conventional treatments, one third of patients receiving the constant electromagnetic fields experienced healing of tubercular cavities. contrast, only one fifth of patients receiving conventional treatment alone experienced such effects. One month into combination treatment, there was no evidence of mycobacterium tuberculosis in the sputum in half the patients relative to only one third of controls.298References296. A. Khomenko, et al., "Use of Millimeter-Range Electromagnetic Radiation in Complex Therapy for Pulmonary Tuberculosis," Millimetrovie Volni v Biologii I Meditcine, (3), 1994, p. 53-61.297. T.V. Kalinina & V.D. Churaev, "Expense with the Use of the EHF-Therapy at Ryasan' Regional Clinical TB Dispensary," Millimetrovie Volni v Biologii i Meditcine, (4), 1994, p. 52-53.298. A.S. Solov'ena, et al., "Use of Constant Magnetic Field for Increasing the Effectiveness of Chemotherapy in Patients with Pulmonary Tuberculosis," Probl Tuberk, 8, 1987, p. 53-56.Ulcers Research Studies (Gastric and Duodenal)http://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESResults of this study showed that the administration of millimetric electromagnetic waves helped to normalize blood properties, subsequently improving the effectiveness of more conventional gastric and duodenal ulcer treatment.303

This study examined the effects of millimeter wave (MW) therapy in 317 patients suffering from duodenal and gastric ulcers. MW therapy consisted of 30 minutes per day exposure of the epigastric area ("Yav'-1" apparatus, 10 mW/cm2, 5.6-mm wavelength) until complete ulcer cicatrization was achieved. Results showed a 95-percent rate of ulcer cicatrization in patients receiving the treatment compared to a 78-percent rate in controls. One year follow up showed a 54-percent ulcer recurrence rate in MW-treated patients, which was markedly less than the rate for controls.306 This controlled study found extremely-high-frequency therapy to be an effective treatment in patients suffering from duodenal ulcers. Treatment consisted of 5-10 exposures, lasting 20-30 minutes, and making use of the G4-142 apparatus (53.5-70.0 GHz frequency range).308This study compared the effects of traditional drug treatment (TDT) to those of microwave resonance therapy (MRT) in patients suffering from duodenal ulcers. Results indicated the mean hospital stay for patients in the TDT group was approximately 22 days. Throughout this period, ulcers healed in 38 percent of patients, were reduced in 17 percent, showed no change in 43 percent, andincreased in 2 percent. No pain relief was seen in 32 percent. contrast, mean discharge time for patients in the MRT group was approximately 12 days. Pain was generally stopped in 3-6 days. Complete healing occurred in 81 percent, a decrease was seen in 16 percent, and ulcer size did not change in just 3 percent. Remission occurred in 98 percent of such patients.310 In this study, microwave resonance therapy (MRT) was administered to 2642 patients suffering from duodenal ulcers and to 78 with gastric ulcers. Treatment involved the use of a G4-142 device (53.6-78.3 GHz, less than 2 mW/cm2 incident power) as well as"Electronika-KVCh" and "Porog-1" devices. Patients received 6-12 daily exposures of between 20 and 25 minutes. Results showed a total ulcer cicatrization in 80 percent of patients, and arrested pain syndrome in almost 100 percent.311References303. M.V. Poslavskii, et al., "Treatment of Peptic Ulcer Electromagnetic Irradiation of the Millimetric Range," Sov Med, (1), 1989, p. 29-31. 306. M.V. Poslavsky, et al., "Experience with Application of Millimeter-Range Radiation for Treatment and Prophylaxis of Stomach and Duodenal Ulcer," Vopr Kurortol Fizioter Lech Fiz Kult, (4), 1989, p. 31-36.308. M.V. Teppone, et al., "Extremely-High Frequency Therapy of Duodenal Ulcer," Klin Med, 69(10), 1991, p. 74-77.310. S.S. Dudka, et al., "A Comparative Assessment of the Efficacy of Drug Therapy and Microwave Resonance Therapy for Ulcerative Disease of the Duodenum," Fundamental and Applied Aspects of the Use of Millimeter Electromagnetic Radiation in Medicine. Abstracts of the 1st All-Union

Symposium with International Participation, May 10-13, 1989, Kiev, Ukraine, p. 195-197.311. V.A. Kutzenok, "Microwave Resonance Therapy of Stomach and Duodenal Ulcers," Fundamental and Applied Aspects of the Use of Millimeter Electromagnetic Radiation in Medicine. Abstracts of the 1st All-Union Symposium with International Participation, May 10-13, 1989, Kiev, Ukraine, p. 192-193.Ulcers Research Studies (Trophic)http://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESThis study examined the use of magnetotherapy coupled with galvanization and intratissue electrophoresis in 86 patients suffering from trophic ulcers. A "Potok-1" apparatus with a density of current equal to 0.05-0.1 mA/cm2 was used to create an electrical field. The "MAG-30" apparatus for low-frequency magnetotherapy with induction of 30 mT and area of exposure of 20 cm2 was applied to a trophic ulcer site at the same time. Results led the authors to conclude that magnetogalvanotherapy is the recommended treatment for trophic ulcers of the lower extremities.299 This review article discusses the theoretical and clinical applications of magnetic field therapy in the treatment of trophic ulcers of the lower limbs.300 This study looked at the effects of conventional trophic ulcer treatment alone and in combination with alternating magnetic field(AMF) or constant magnetic field (CMF) exposures in a group of patients suffering from various types of trophic ulcers of the lower limbs. Results showed an average hospital stay of 31 days in the CMF group and 27 days in the AMF group, compared to 40 days among controls. Based on these and related findings, the authors suggest combination AMF therapy to be most effective.304 This placebo-controlled study examined the effects of pulsed electromagnetic fields in the treatment of decubitus ulcers in hospitalized elderly patients with stage II and III pressure ulcers. Patients received daily PEMF stimulation in conjunction with conventional treatment for a period of up to 5 weeks. The findings were that combined PEMF/conventional treatment was superior to conventional treatment and to the placebo received controls.305Results of this study found that the daily use of electromagnetolaser therapy decreased mean healing time in patients suffering from lower extremity trophic ulcers to approximately 18 days, compared with approximately 26 days in patients receiving laser therapy alone.307 This double-blind, placebo-controlled study found that treatment with nonthermal pulsed electromagnetic energy (PEMET) accelerated would healing in spinal cord injury patients suffering from stage II and III pressure ulcers. PEMET treatment consisted of pulsed 27.12-MHz energy produced via a Diapulse device. Energy was delivered the use of a treatment head placed in wound dressings, in 30-minute periods twice a

day for 12 weeks or until sores healed.312 This double-blind, placebo-controlled study examined the effects of pulsed electromagnetic fields (75 Hz, 2.7 mT) applied 4 hours per day for a maximum of 3 months coupled with conventional therapies in patients suffering from trophic lesions. Results showed the treatment to have positive effects, but only on small lesions.314References299. A.V. Alekseenko, et al., "Use of Magnetic Therapy Combined with Galvanization and Tissue Electrophoresis in the Treatment of Trophic Ulcers," Klin Khir, (7-8), 1993, p. 31-34.300. A. Sieron, et al., "Use of Magnetic Field in Treatment of Trophic Leg Ulcers," Pol Tyg Lek, 46(37-39), September 1991, p. 717- 719.304. I.G. Sukhotnik, "Comparative Effectiveness of Using Constant and Alternating Magnetic Fields in the Treatment of Trophic Ulcers," Vest Khir, 144(6), 1990, p. 123-124.305. S. Comorosan, et al., "The Effect of Diapulse Therapy on the Healing of Decubitus Ulcer," Romanian Journal of Physiol, 30(1- 2), 1993, p. 41-45.307. F.V. Galimzianov, "Laser and Electromagnetolaser Therapy for Trophic Ulcers of the Lower Extremities in Chronic VenousInsufficiency," Vestn Khir Im I I Grek, 152(5-6), 1994, p. 70-72.312. C.A. Salzberg, et al., "The Effects of Non-Thermal Pulsed Electromagnetic Energy on Wound Healing of Pressure Ulcers in Spinal Cord-Injured Patients: A Randomized, Double-Blind Study," Wounds: A Compendium of Clinical Research and Practice, 7(1), 1995, p. 11-16.314. M. Jeran, et al., "PEMF Stimulation of Skin Ulcers of Venous Origin in Humans: Preliminary Report of a Double Blind Study," Journal of Bioelectr, 6(2), 1987, p. 181-188.Urinary Problems Research Studieshttp://www.garynull.com/Documents/magnets.htm#PEER-REVIEWED SCIENTIFIC STUDIESIn this article, the authors report on their successful use of magnetic-laser therapy in inflammations of the urinary system in a urological clinic setting.316Results of this study showed magnetolaser therapy to be effective in the treatment of patients suffering from urolithiasis (stone formation). Magnetolaser therapy involved the use of a Milita device with a 35-mT magnetic field.317References316. O.B. Loran, et al., "Magnetic-laser Therapy in Inflammatory and Posttraumatic Lesions of the Urinary System," Urol Nefrol (Mosk), (5), September-October 1996, p. 10-14.317. V.P. Avdoshin, et al., "Assessment of Magnetolaser Therapy in Comparison with Other Methods of Treatment of Patients with Urolithiasis," Fiz Med, 4(1-2), 1994, p. 102-103.

Static Magnetic Field Therapy for Symptomatic DiabeticNeuropathy: A Randomized, Double-Blind,Placebo-Controlled TrialMichael I. Weintraub, MD, FACP, FAAN, Gil I. Wolfe, MD, Richard A. Barohn, MD, Steven P. Cole, PhD,Gareth J. Parry, MD, Ghazala Hayat, MD, Jeffrey A. Cohen, MD, Jeffrey C. Page, DPM,Mark B. Bromberg, MD, Sherwyn L. Schwartz, MD, and the Magnetic Research GroupABSTRACT. Weintraub MI, Wolfe GI, Barohn RA, Cole SP, Parry GJ, Hayat G, Cohen JA, Page JC, Bromberg MB, Schwartz SL, and the Magnetic Research Group. Static magnetic field therapy for symptomatic diabetic neuropathy: a randomized, double-blind, placebo-controlled trial. Arch Phys Med Rehabil 2003;84:736-46.Objective: To determine if constant wearing of multipolar, static magnetic 450G) shoe insoles can reduce neuropathic pain and quality of life (QOL) scores in symptomatic diabetic peripheral neuropathy (DPN).Design: Randomized, placebo-control, parallel study.Setting: Forty-eight centers in 27 states.Participants: Three hundred seventy-five subjects with DPN stage II or III were randomly assigned to wear constantly magnetized insoles for 4 months; the placebo group wore similar, unmagnetized device.Intervention: Nerve conduction and/or quantified sensory testing were performed serially.Main Outcome Measures: Daily visual analog scale scores for numbness or tingling and burning and QOL issues were tabulated over 4 months. Secondary measures included nerve conduction changes, role of placebo, and safety issues. Analysis of variance (ANOVA), analysis of covariance (ANCOVA), and chi-square analysis were performed. Results: There were statistically significant reductions during the third and fourth months in burning (mean change for magnet treatment, _12%; for sham, _3%; P_.05, ANCOVA), numbness and tingling (magnet, _10%; sham, _1%; P_.05, ANCOVA), and exercise-induced foot pain (magnet, _12%; sham, _4%; P_.05, ANCOVA). For a subset of patients with baseline severe pain, statistically significant reductions occurredfrom baseline through the fourth month in numbness and tingling (magnet, _32%; sham, _14%; P_.01, ANOVA) and foot pain (magnet, _41%; sham, _21%; P_.01, ANOVA).Conclusions: Static magnetic fields can penetrate up to 20mm and appear to target the ectopic firing nociceptors in the epidermis and dermis. Analgesic benefits were achieved over time.Key Words: Diabetic neuropathies; Magnetics; Rehabilitation.

© 2003 by the American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and RehabilitationDIABETIC PERIPHERAL NEUROPATHY (DPN) is a common and often disabling complication of diabetes mellitus (DM). Depending on criteria, DPN is estimated to occur in 50% to 90% of individuals with diabetes for more than10 years.1-4 As many as half of the 16 million diabetics in the United States will experience neuropathic pain at some point in their lives.5-9 DPN begins insidiously, presenting as a symmetrical sensory polyneuropathy that follows a stocking-glove pattern. Selective involvement of unmyelinated C fibers andsmall myelinated A delta fibers produces pain of the burning dysesthetic type and is often accompanied by hyperalgesia and allodynia in the feet.7,10-12 Neuropathic pain symptoms fluctuate and can be described as superficial, deep, aching, lancinating, constant, or episodic. Complaints are often worse at night.Although initial symptoms and the course of DPN vary, once neuropathic pain is established, it is almost always progressive, leading to increased discomfort and disability.6,13-15 Furthermore, individuals with DPN are at augmented risk for foot trauma and infections that may necessitate amputative procedures. 2,16From a pathophysiologic standpoint, these symptoms are believed to be secondary to ectopic firing of nociceptive afferent axons that are undergoing degeneration.7,9-12 This ectopic depolarization appears to be related to dysregulated expression of sodium and calcium channels17-19 and a deficit in the potassium- internal rectifying channel.20-22 Neurons at the level of the dorsal root ganglion (DRG) also become hyperexcitable after peripheral nerve injury, presumably because of loss of peripheral inhibitory influences.23 Currently, there are no treatments that reverse or arrest progressive diabetic polyneuropathy.24 A variety of standard oral therapies used for symptomaticNeuropathic pain include tricyclic antidepressants,25 antiepileptic medications,26 and narcotic analgesics.27,28 Additionally, topical products such as capsaicin29,30 have been applied and have produced incomplete pain relief and significant side effects. Overall, the results have been disappointing and associated with significant side effects.15,31,32 The search for reliable, safe, and effective mainstream treatments for the neuropathic pain of DPN remains a major challenge,13,15,25-27,31-34 and, not surprisingly, patients have explored a variety of alternative approaches, including homeopathy, acupuncture, and magnetic From the Department of Neurology, New York Medical College, Valhalla, NY (Weintraub); University of Texas, Southwestern Medical Center, Dallas, TX (Wolfe, Barohn); Research Design Inc, Yorktown Heights, NY (Cole); University of Minnesota, Minneapolis, MN (Parry); St. Louis University, St. Louis, MO (Hayat); Kaiser- Permanente Medical Group, Denver, CO (Cohen); California College of Podiatric Medicine, San Francisco, CA (Page); University of Utah, Salt Lake City, UT (Bromberg); and Diabetes

and Glandular Disease Clinic, San Antonio, TX (Schwartz). Supported by Nu-Magnetics Inc and Nikken Inc. Presented in part at the Joint Conference of the American Congress of RehabilitationMedicine and the American Society of Neurorehabilitation, October 5, 2002,Philadelphia, PA.No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit upon the author(s) or upon any organization with which the author(s) is/are associated.Reprint requests to Michael I. Weintraub, MD, Dept of Neurology and Medicine, New York Medical College, 325 S Highland Ave, Briarcliff Manor, NY 10510,e-mail: miwneuro@pol.net.0003-9993/03/8405-7836$30.00/0doi:10.1016/S0003-9993(03)00106-0Arch Phys Med Rehabil Vol 84, May 2003