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B. pseudomallei : Role of MALDI-TOF. Rob Baird Royal Darwin Hospital. MALDI-TOF. What is MALDI TOF? Role of MALDI TOF – current evidence Where does it fit in the current/future diagnostic algorithms?. Resistance. VITEK 2. Serology. Resistance. Serology. VITEK 2. MALDI -TOF. - PowerPoint PPT Presentation
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B. pseudomallei: Role of MALDI-TOF
Rob BairdRoyal Darwin Hospital
MALDI-TOF
What is MALDI TOF?Role of MALDI TOF – current evidenceWhere does it fit in the current/future
diagnostic algorithms?
VITEK 2 Resistance
Serology
VITEK 2 Resistance
Serology
MALDI -TOF
5 Minutes
Rapid Result deliveryby MALDI TOF
Identifies > 96% of clinically relevant pathogensResults within minutesCost less than 50 cents/isolate (compared to $5.00 isolate currently)
Replaces over 20 current biochemical identification assaysIdentification down to species levelIdentifies bacteria & fungi
Next generation Direct detection out of blood cultures/wound swabs
Provisional susceptibility profiles
MALDI-TOF and Burkholderia
2007
2013
2013