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A Look into Current Research and Future Prospects

By,Annapurna

Nikhil

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The Eye Human Eye is similar to a camera Macula provides the highest resolution of the image which we see. Macula is comprised of multiple layers of cells which process the initial “analog”light energy entering the eye into “digital” electrochemical impulses. Human eye has nearly 100 million photoreceptors.

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Inability to see

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Causes of BlindnessDamage to:Clear Structures in the eye, that allow the

light to pass throughThe nerves within the eyeOptic NerveBrain

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Diseases of the Eye

Retinitis PigmentosaMacular Degeneration

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NORMAL EYE DEFECTIVE EYE

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NORMAL EYE DEFECTIVE EYE

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BIONIC EYE ?Bio-electronic eyeElectronic device which replaces

functionality of a part or whole of the eyeUsed for replacing functionality (or)Adding functionality to the eye

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Regions of Implantation

RetinaOptic NerveLateral geniculate

bodyVisual Cortex

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Fundamental idea behind ASRASR is a solid state biocompatible chip which contains an

array of photo receptors ,and is implanted to replace the functionality of the defective photoreceptors .

ASR consists of a microchip containing thousands of photo diodes.

Detects light and converts it into electrical impulses.Eliminates the need for any wires,  batteries  or other

secondary devices to supply power.Artificial vision created by the controlled electric

stimulation of the retina has color.

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Approaches Towards Retinal Prosthetic Implantation

Epiretinal Approach involves a semiconductor based device positioned on the surface of the retina to try to simulate the remaining overlying cells of the retina.

Subretinal Approach involves implanting the ASR chip behind the

retina to simulate the remaining viable cells.

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Enhancement of the image quality using the ASR

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Limitations Of ASR’sASR is designed to interface and function with the retina

that has partial outer retinal degeneration.

ASR can be applied only when the photoreceptor cellular layer of the retina is damaged but the remaining cellular layers are still functional.

Conditions amenable to treatment with ASR’s include some forms of long-term retinal detachment, Usher’s syndrome, Cone- Rod Dystrophy.

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ASR implanted into the eye

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Multiple Unit Artificial Retina Chipset (MARC)

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Conceptual Design

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MARC System Block Diagram

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Block diagram of Image Acquisition System

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MARC Hermetic Sealing and Positioning

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Advantages of MARC system

• Compact Size – 6x6 mm

• Diagnostic Capability

• Reduction of stress upon retina

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OverviewBiology of the EyeMIT – Harvard DeviceASR – Artificial Silicon RetinaMARC – Multiple Unit Artificial Retina Chip

Set System

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Conclusion Its been 40 years since Arne Larsson received the first fully

implanted cardiac pacemaker at the Karolinska Institute in Stockholm.

Researchers throughout the world have looked for ways to improve people's lives with artificial, bionic devices.

Bionic devices are being developed to do more than replace defective parts.

Researchers are also using them to fight illnesses.

Providing power to run bionic implants and making connections to the brain's control system pose the two great challenges for biomedical engineering.

We are now looking at devices like bionic arms, tongues, noses etc.