Briar Chemicals Presentation _August 2016

Growing Successful Global Partnerships

Briar Chemicals GROWING SUCCESSFUL GLOBAL PARTNERSHIPS

Company Overview 2016


Briar Chemicals provides world class contract manufacturing services to industry-leading companies in the agrochemical, fine and specialty sectors.

Exceptional asset integrity and responsiveness in a challenging business environment ensure that customers experience reliability and excellent customer service.

Our culture of operational excellence underpins everything we do, deriving benefits for all stakeholders through continuous improvement.

Key performance indicators include safety (RIDDOR), quality on time in full (QOTIF), raw material usage efficiency (yield optimisation) and overall equipment effectiveness (OEE).

Your dependable partner of choice for custom and contract chemical manufacturing

220 highly skilled employees

Global customer base with >95% of production exported

Sales revenue ~ UK £45 million (Euro €60 million, US $75 million, Yen 8000 million)

Upper Tier COMAH establishment

(Seveso III Directive)

Extensive site infrastructure including energy generation and waste treatment facilities

Key Facts

Who we are


Long expertise in contract manufacturing, high quality asset base, established

reputation for manufacturing excellence and dependability

Site acquired by Bayer CropScience in 2002

In 2012, Briar Chemicals became an independently-

operated Contract Manufacturer, wholly owned

by Aurelius AG

First manufacturing took place in 1956 as May &

Baker and was later renamed Rhone-Poulenc

Our heritage Manufacturing excellence and dependability


Senior Management Team

Briar Chemicals management team has extensive experience within the chemical manufacturing sector. This team has delivered significant growth and established a strong track-record in growing the business globally.

Tim Green Site Manager & Executive Director

Bert Botha Head of Engineering

Susan Brench Head of Commercial

Phil Moore Logistics Manager

Graham Temple Operations Manager

Our values define who we are, how we work and what we aspire to be as an organisation.

Safety | Integrity | Quality | Delivery | People


Our global presence Supporting your business worldwide

Expertise in import and export

regulations

Transportation of dangerous goods by road, rail, sea

and air

Over 50 years experience of

shipping to 25+ countries

Trusted partner across Europe,

Americas and Asia

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Site Facilities & Services

COMBINED HEAT & POWER (CHP) UNIT

Flexible approach to electricity generation

Gas /oil fired turbine

Generates 4.4MW power and 17000 kg/hour steam

UTILITIES

Nitrogen - site generated and high purity

Compressed air to 7 barg and - 40°C dew point

Steam heating allows jacket services up to 17 barg

Water available from boreholes and mains (demineralised from the CHP unit)

Glycol cooling/heating provides jacket services between -17 deg C and +90 deg C

Cooling water supplied by three independent systems

Site area 46 hectares (114 acres) with 13.6 hectares available for development

60 years of production on site

Extensive range of solids and liquids manufacturing assets, with a total reactor capacity in excess of 700 m3


Fentox® hydrogen peroxide oxidation treatment plant (commissioned 2014 by Eisenmann)

Treatment, at source, on a number of our production units

Real-time analysis of effluent discharges

Final onsite treatment of aqueous effluent prior to discharge to 3rd Party treatment facilities

Collection and testing of all rainwater run-off

3600m3 firefighting water tank and full containment of all potential fire water run-off

Treatment and recycle of copper salts

Solvent recovery and recycle

Comprehensive fire detection systems across the site

Firefighting water distribution linked to on-plant fire suppression systems

ENVIRONMENTAL PROTECTION We aim to minimise the impact on the environment from our activities, investing more

than £6 million each year to maintain and improve site infrastructure


We operate an Upper Tier establishment under the COMAH (Control of Major Accident Hazards) regulations. Our SHEQ philosophy forms an integral part of our business and is demonstrated through our commitment to:

Maintaining the health and safety of all

Minimising our impact on the environment

Ensuring we do nothing to disturb, disrupt or annoy our neighbours

Satisfying our customers’ needs

Member of Chemical Industries Association and EFCG (CEFIC)

Adheres to the guiding principles of Responsible Care

ISO 9001 & 14001 Certified

Community & Social Responsibility Building strong community relations

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Analytical Services We are proud of our reputation.

GROWING SUCCESSFUL GLOBAL PARTNERSHIPS


Environmental monitoring analytical techniques

Gas chromatographic analytical techniques (GC)

High performance liquid chromatographic analytical techniques (HPLC)

GC-MS and HPLC-MS

Inhibition to nitrification analytical techniques

Problem solving, troubleshooting and non-routine analytical support

Laboratory scale from grams through to 50 litres

Extensive analytical method development expertise

Development, validation and implementation of analytical methods for new and existing processes

Ion chromatographic techniques (IC)

Inductively Coupled Plasma Optical Emission spectrometry (ICP-OES) for metals analysis

UV / FTIR and Wet Chemistry

KILO LAB FACILITIES As part of our contract and custom manufacturing service package, we offer

extensive process development and analytical support services


Chemical Diversity & Expertise

Diazotisation Cyanation Iodination

Chlorination

Solvent recycle & recovery

Copper salts recovery

Liquid herbicide formulation Nitration

Sulphonamide formation

Sulphur Dioxide reactions

Oxidation

Ammonolysis

Esterification

Bromination


Aromatic nitrile synthesis. Large scale handling of cyanide salts including CuCN & NaCN

Sulphonamide synthesis from diazonium salts & SO2. Bulk handling of sulphur dioxide & ammonia.

Oxidation reactions using sodium chlorate, potassium permanganate & hydrogen peroxide.

Bromination & iodination chemistry. Use of various halogenating reagents including elemental bromine & iodine.

Diazotisation reactions.

Esterification and amidation reactions using anhydrides & acid chlorides.

Acid chloride formation using thionyl chloride.

Nitration of aromatic compounds via nitrosation – oxidation & direct nitration routes.

CO2H

RR

MeKMnO4

NH2

R R

N2+.Cl

-I

R

KINaNO2

HCl

O R'

O

RR

OH(R'CO)2O

CO2H

R R

Cl

O

SOCl2

O

NHR'

R

R'NH2

NO2

R R

NO2

R

NaNO2HNO3,

H2SO4 HNO3

Technologies SELECTED EXAMPLES

R

X CN

R

CuCNHal

X

I

R R

Br

R

Br2 orIC l or

l2, OH-

Br-, [O]

S

NH2.HCl

R R

S

N2+Cl

-

S

SO2Cl

R R

S

SO2NH2

SO2 NH3

HCI

NaNO2

Or ICI

I2, OH-


Manufacturing

Operational excellence underpins everything we do.



Total reactor capacity in excess of 700m3

Materials of construction include Glass Lined MS, Stainless Steel, Hastelloy, Titanium

Reaction vessels from 2.3m3 to 25m3

Batch and continuous distillation

Recovery and recycle of solvents and copper salt

Bulk storage for raw materials, intermediates, finished products

Solids handling capability to include pan and rotary paddle driers, centrifuges, pressure filters, belt filters, rotary sieves, milling equipment

Reagents include acids, acid chlorides, amines, ammonia, bromine, cyanides, hydrogen bromide, hydrogen peroxide, iodine, phenol, sulphur dioxide, solvents, thionyl chloride

Formulation and packaging - stand alone, automated facility

MANUFACTURING ASSETS Once a process has been developed and scaled up, we offer an extensive range of

solids and liquids manufacturing assets


Project Delivery

Enquiry Costing Lab Work Development Production

SUCCESSFUL PROJECT DELIVERY

Technology &

Capability

SHEQ &

Regulatory Customer

Service

People &

Organisation

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Case Study | Optimisation of a multi-stage synthesis

Overview

New three stage synthesis introduced within 18 months

of receipt of enquiry

Required handling of two new hazardous raw materials

Specialised, cost effective handling facilities were successfully installed (using in-house design) for ammonia and sulphur dioxide

Challenges

Although the process was successfully scaled up and implemented there were

some challenges to address Lower than expected yields due to

competing side reactions Whilst most impurities could be

successfully removed from the product during the isolation procedures, one impurity was consistently found in the isolated product at levels approaching the specification limit

A liquid-liquid phase separation step proved problematic - long settling times and poor separation interface

One step of the process was quickly identified as being the main low yielding stage and became the focus of attention

Benefits

Our approach - identification of process changes with the

following benefits

+25% yield improvement Process impurity reduced by > 50%

and further reductions were realised as the process became established

Phase separation step improved Settling times reduced by 70% and

very clean phase interfaces achieved Repeat business secured

All our processes are subject to continuous improvement with primary focus on yields, cycle times and waste minimisation


Formulation & Packing Safe, efficient, on time.



Facilities built in 1980

Site area 6 hectares

Formulation vessels from 14,000 – 27,000 litres

Bulk storage (including heated tanks) for raw materials and formulations

Extensive warehousing capability and logistics expertise

Warehouse capacity of 1.1 million litres of packed product

Bulk liquid storage available for finished products and raw materials

Flammable storage areas

Dangerous goods and UN certified packaging competence

Export logistics expertise (> 95% export)

FORMULATION & PACKING The compact and efficient layout of our stand-alone site allows us to respond

quickly to customer needs


Formulation & Packing

FORMULATION & MATERIALS HANDLING

Heated bulk storage systems, heat traced lines between vessels and storages

Multiple drum heating ovens (total capacity 186 drums) for handling of solid materials

Bulk storage capacity 1.8 million litres of formulated product and 1.2 million litres of bulk solvents and actives

Minimum batch size 4,000 litres

Tanker and IBC offloading and filling with steam heating capability

Long-established cross contamination prevention protocols in place – product segregation and cleaning to below 5ppm routinely achievable

PACKING & QUALITY CONTROL

On site QC laboratory: wet chemistry, HPLC, GC

Pipeline internal gauge (“Pigging”) technology and Clean in Place (CIP) for fast, efficient, product changeover

6 packing lines capable of packing from 0.25 litre to 200 litre packs at speeds up to 30 containers per minute

Packing output of up to 90,000 litres/day

Robotic palletising equipment with auto stretch wrapping

On site workshop and tooling for efficient product changeover


Formulation & Packing

LIQUID HERBICIDE SPECIALIST

Emulsifiable Concentrates (EC)

Soluble Concentrates (SL)

Microemulsions (ME)

Suspoemulsions (SE)


Case Study | Formulation & Packing

Overview

New customer approached Briar with a formulation and

packing opportunity

Rigorous but efficient management of change procedures in place to manage new product introductions

Challenges Outcomes

Within five days from receipt of enquiry the new project

commenced

New formulation procedure completed per the Briar Process Change Authorisation system

New filling line parts manufactured, tested and commissioned (three bottle sizes on two lines) and operator training completed

13 new raw materials accommodated, plus customer specified bottles, caps, packing cases and labels

Required handling of multiple new pack sizes and formulation raw materials

New filling line parts needed

Short timelines and new requirements


Our services Your dependable partner of choice.



Fast response to customer enquiries

Total confidentiality and IP protection

Laboratory and scale-up capabilities

Process safety and hazard studies

Analytical method development

Regulatory compliance, operational excellence

OUR CAPABILITIES

Project Management and commissioning

Process development and optimization

Raw materials and finished product storage

Dedicated, highly trained and flexible teams

Rigorous cross contamination prevention protocols

Flexible formulation and packing facility

Analytical Services

Technologies Formulation

& Packing Supply Chain Management

Project Management


What we deliver Excellence in the technologies and services we offer

Highest standards of integrity and IP protection

No compromise on SHEQ

Excellent value (even if we are not the least cost option)

Fast in development to commercial scale

Cost effective CAPEX implementation with speed

We do what we say we will do


Contact Us

For new project and commercial enquiries

Susan Brench, Head of Commercial

E: [email protected]

M: +44 (0) 7793 495 652

www.briarchemicals.com

Documents

Briar Chemicals Presentation _August 2016