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KISHAN El" AL: PERINATAL OUTCOME AT BENGHAZI 10. Adeleye JA. A two year study of caesarian section emd perinatal mortality at the University College Hospital,l'oadan,Nigeria.Ea~AfrMed J 1982;59:383-389 11. Brown IM. Community obstetrics in tropics. Post grad Doctor 1985;8:98-103 12. Kapoor SIC Reddaiah VP, Lobo J. Antenatal ca,-e and perinatal mortality. Indian J Pediatr 1985;52:159-162 13. Damodt B, Mathur I-IN, Sharma PN. Some obse~valic~ on perinatalmortality in rural health centre. Indian J Pediatr 1983;50:629-633 615 14. Prentice AM, et al. Long term energy balance in child bearing Gambian women.AmY ClinNmr 1981;34:2790-9 15. Prentic~ AM et tl. Prenatal dieta~ sup- plementation of African women end birth weight. Lancet 1983; i:489-492 16. Stanfield JP, Galzaka A. Neonatal tetanus in the world today. Bulletin World Hlth Or& 1984;62:647-669 17. Expandedprogrsmme on immunization. Impact of trainedtraditionalbirth aaendmts and tetmus toxoid on neonatal mortality. Weekly Epidemiological Record 1983;55:93-94 CAUSAL AGENT FOR EXANTHEM SUBITUM Exanthem subitum (roseola infantum) is a common disease of infancy charactedsed by high fever for a few days and the appearance of a rash coinciding with subsidence of the fever. Symptoms ae usually mild, but febrile convulsions have been reported. Since haematogenous transmission of infection was documented in the 1950s, it has been widely believed that the disease is caused by a virus. However, the causal agent had not been identified. A virus was isolated from the peripheral blood lymphocytes of patients with exanthem subitum, cultured successfully in cord blood lymphocytes, and shown to be anfigenicaUy related to human herpesvirus-6 CrIHV-6). Morphological features, as studied by thin-section electronmicroscopy,resembled those of herpes group viruses. Convalescent phase serum samples, tested against the new viral antigen and HHV-6 antigen, showed seroconversion. The r~sults strongly suggest that the newly isolated virus is identical or closely related to HHV-6 and is the causal agent for exanthem subitum. Abstrated from

Causal agent for exanthem subitum

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KISHAN El" AL: PERINATAL OUTCOME AT BENGHAZI

10. Adeleye JA. A two year study of caesarian section emd perinatal mortality at the University College Hospital, l'oadan, Nigeria.Ea~AfrMed J 1982;59:383-389

11. Brown IM. Community obstetrics in tropics. Post grad Doctor 1985;8:98-103

12. Kapoor SIC Reddaiah VP, Lobo J. Antenatal ca,-e and perinatal mortality. Indian J Pediatr 1985;52:159-162

13. Damodt B, Mathur I-IN, Sharma PN. Some obse~valic~ on perinatal mortality in rural health centre. Indian J Pediatr 1983;50:629-633

615

14. Prentice AM, et al. Long term energy balance in child bearing Gambian women.AmY ClinNmr 1981 ;34:2790-9

15. Prentic~ AM et tl. Prenatal dieta~ sup- plementation of African women end birth weight. Lancet 1983; i:489-492

16. Stanfield JP, Galzaka A. Neonatal tetanus in the world today. Bulletin World Hlth Or& 1984;62:647-669

17. Expanded progrsmme on immunization. Impact of trained traditional birth aaendmts and tetmus toxoid on neonatal mortality. Weekly Epidemiological Record 1983;55:93-94

CAUSAL AGENT FOR EXANTHEM SUBITUM

Exanthem subitum (roseola infantum) is a common disease of infancy charactedsed by

high fever for a few days and the appearance of a rash coinciding with subsidence of the fever.

Symptoms ae usually mild, but febrile convulsions have been reported. Since haematogenous

transmission of infection was documented in the 1950s, it has been widely believed that the disease is caused by a virus. However, the causal agent had not been identified.

A virus was isolated from the peripheral blood lymphocytes of patients with exanthem

subitum, cultured successfully in cord blood lymphocytes, and shown to be anfigenicaUy related

to human herpesvirus-6 CrIHV-6). Morphological features, as studied by thin-section

electronmicroscopy, resembled those of herpes group viruses. Convalescent phase serum samples,

tested against the new viral antigen and HHV-6 antigen, showed seroconversion. The r~sults

strongly suggest that the newly isolated virus is identical or closely related to HHV-6 and is the

causal agent for exanthem subitum.

Abstrated from