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Cellular Respiration: Aerobic Respiration. Krebs Cycle Electron Transport Chain and ATP Synthase. The Krebs Cycle. Occurs in the mitochondria. Produces high-energy molecules (NADH and FADH2), CO2 and 1 ATP Also called the citric acid cycle. Step 1. - PowerPoint PPT Presentation
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Cellular Respiration: Aerobic Respiration
Krebs Cycle Electron Transport Chain
and ATP Synthase
The Krebs Cycle• Occurs in the
mitochondria.• Produces high-
energy molecules (NADH and FADH2), CO2 and 1 ATP
• Also called the citric acid cycle
Step 1
• Pyruvic acid loses one carbon and two oxygen to form CO2 and Acetyl-CoA
• During this step high energy molecule of NADH is formed
Step 2
• Part of Acetyl-CoA combines with a 4-carbon compound to form citric acid
• During this step two high energy molecules are formed: one FADH2 and one NADH
Step 3
• Citric Acid loses one carbon and two oxygen to form CO2 and a 5-carbon compound
• During this step a high energy molecule of NADH is formed
Step 4
• The 5 carbon compound loses one carbon and two oxygen to form CO2 and a 4-carbon compound
• During this step one high energy molecule of NADH is formed and one ATP is formed
Overall Products of the Krebs Cycle• How many CO2 are
formed?• How many NADH are
formed?• How many FADH2 are
formed?• How many ATP are
formed?
Electron Transport Chain
• High energy electrons in NADH and FADH2 created during glycolysis and the Krebs cycle are used to pump H+ ions across the inner membrane of mitochondria to create a concentration gradient.
• Oxygen acts as a final electron acceptor combining with low energy electrons and H+ ions to form H2O
ATP Synthase
• The push of H+ ions flowing down their concentration gradient through an enzyme called ATP Synthase converts ADP into ATP ADP ATP
Total ATP formed from aerobic respiration from one molecule of glucose
• 2 ATP from glycolysis• 4 ATP from the 2 NADH
formed in glycolysis• 2 ATP from the Krebs
cycle• 24 ATP from the 8 NADH
formed from the Krebs cycle
• 2 ATP from the 2 FADH2 formed from Krebs cycle