Cellular Respiration and ATP

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    12-Jan-2016

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Break down of cellular respiration with ATP loss and gains specified in both anaerobic and aerobic metabolism. Summary that I revised from an instructor handout for a pathophysiology class part of a baccalaureate nursing curriculum.

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ATP Production from One Molecule of Glucose

ATP Production from One Molecule of Glucose

Oxidation of glucose

C6H12O6(s) + 6 O2(g) 6 CO2(g) + 6 H2O (l) + heatThe following steps are required for Cellular Respiration

1. GLYCOLYSIS- the splitting of sugar glucose is converted to pyruvic acid

Glucose + 2 NAD++ 2 Pi+ 2 ADP 2pyruvate+ 2 NADH + 2 ATP + 2 H++ 2 H2O + heat cytosol/cytoplasm anaerobic respiration

uses

2 ATP 2 NAD+ and 2 Pi 2 NADH and 2H+ 4 ADP

yields

2 pyruvate (pyruvic acid) 2 NADH (electron carriers) 4 ATP (2 net ATP because 2 are used to begin glycolysis)2. TRANSITION REACTION-connects glycolysis to the Krebs Cycle/Citric Acid Cycle/Tricarboxylic Acid Pyruvic acid is converted to acetyl CoA mitochondrial matrix aerobic respiration uses 2 NAD+ 2 CoA yields 2 NADH 2 Acetyl CoA 2 H+ 2 CO2 2 ATP3. KREBS CYCLE--CITRIC ACID CYCLE--TRICARBOXYLIC ACID CYCLE mitochondrial matrix aerobic respiration

uses 6 NAD+ 2 FAD

2 GDP and 2 Pi 2 ADP yields 6 NADH and 6 H+ 2 FADH2 2 ATP

2 GTP4. ELECTRON TRANSPORT SYSTEM (ETS)

mitochondrial cristae aerobic respiration most ATP is created here

Total yields

glycolysis --------------2 NADH yield 4 ATP (2 net) transition reaction ----2 NADH yield 6 ATP Krebs cycle ----------- 6 NADH yield 18 ATP Krebs cycle ----------- 2 FADH2 yield 4 ATP

TOTAL 38 ATP

Total net ATP production of Cellular Respiration (Anaerobic + Aerobic) = 36

Inferior vena cavaRight atrium

Right AV valve/tricuspid

Ventricular filling done-diastole

Insulin promotes cellular uptake of glucose and other nutrients

Bicep originates at the humeral head

Inserts at the

Dorsal afferent sensory- to the brain

Ventral efferent motor- to the body

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