Cellular Respiration

continued

Review

Purpose of cellular respiration is to convert ________ into _____ energy.

Aerobic conditions: the pathway is

glucose ATP

glycolysis Pyruvate oxidation Krebs Cycle ETC

Review: KEY TERMS

Phosphorylation Adding a phosphate group (PO4) to a molecule

Substrate-level phosphorylation occurs in glycolysis Oxidative phosphorylation occurs in ETC

Kinase an enzyme that transfers a phosphate group

(PO4) to a molecule

Glycolysis

Glucose gets phosphorylated by a kinase That means that P group from ATP is used

Phosphorylation destabilizes glucose Glucose splits into 2 pyruvate molecules

Net products from Glycolysis (per glucose)

2 pyruvate 2 NADH 2 ATP Total energy = -61.3 kJ

Pyruvate Oxidation

Pyruvate enters mitochondria and is converted to acetyl CoA (by acetyl coenzyme A)

Occurs in the mitochondrial matrix Electron carriers store the energy from the

reaction (to be used in the ETC)

Pyruvate Oxidation

The Krebs Cycle (aka TCA cycle, aka Citric Acid cycle)

Acetyl CoA is completely degraded to CO2 and H2O

Metabolism is dominated by the Kreb’s cycle

Occurs in the mitochondrial matrix

Note: Major amounts of acetyl CoA are also produced by the oxidation of fatty acids (BETA OXIDATION)

Krebs Cycle

Per Glucose

2 full turns: 2ATP 8NADH 4FADH2

March Break Homework

Make a “Cheat Sheet” for each of glycolysis (and pyruvate oxidation), Krebs cycle and ETC. Include

structure of each molecule Enzymes ADP, ATP, NAD, NADH, other products

Highlight or use color to show what’s happening.