Chapter 7

Respiration

Cellular Respiration (p 222) process that releases energy… by breaking

down glucose (sugar)… and other food molecules… in the presence of oxygen

Energy is released in a SLOW controlled way Video http://videos.howstuffworks.com/hsw/12580-the-

science-of-life-cellular-respiration-video.htm

3 stages of Cellular Respiration

(Each step captures some energy and makes it ATP)

Glycolysis

Krebs Cycle Fermentation

Electron Transport Chain

Glycolysis

1 molecule of glucose is broken down in ½ , producing 2 molecules of pyruvic acid and a 3 carbon compound-

FACTS 1st step of cell resp. 2 ATP molecules into its “account” to get

glycolysis going Energy releasing process (2ATP→4ATP) Amount of energy made is small- but

happens quickly 1,000’s of ATP made in a few milli-seconds

Takes place in cytoplasm

The formula for aerobic cellular respiration is C6H12O6 + O2 → CO2 + H2O + Energy (as

ATP)

The word equation for this is: Glucose + Oxygen → Carbon dioxide + Water

+ Energy (as ATP)

http://www.biologyinmotion.com/atp/index.html

ATP- charged battery ADP uncharged battery

No oxygen?

During fermentation: cells convert NADH to NAD+ by

passing high-energy electrons back to pyruvic acid.

This action converts NADH back into the electron carrier NAD+,

…..allows glycolysis to continue producing a steady supply of ATP.

Fermentation

Sore Muscles, wine and beer, bread… Def: releases energy from food by

making ATP WITHOUT oxygen (anaerobic)

2 typesAlcoholic FermentationLactic Acid Fermentation

Alcoholic

Used by yeast and other microbes Causes dough to rise CO² is released ( this is why bread has

spaces)

Make wine? Yeast, grapes, sugar and dark place cool place….and a way for Co2 bubbles to escape-

Lactic Acid Fermentation

Pyruvic acid → Lactic Acid Vigorous Exercise…(sprinting)

after a while oxygen cannot reach the muscles fast enough and you run out…

so in order to keep going anyway…your muscles keep producing ATP thru Lactic Acid Fermentation…

sore muscles

Uni-cellular org produce LA as a waste during fermentation Kimchi Cheese Yogurt Buttermilk

Have Oxygen ?

At the end of glycolysis, about 90 percent of the chemical energy that was available in glucose is still unused, locked in the high-energy electrons of pyruvic acid.

To extract the rest of that energy, the cell turns to one of the world's most powerful electron acceptors—oxygen.

Oxygen is required for the final steps of cellular respiration. Because the pathways of cellular respiration require oxygen, they are said to be aerobic.

Krebs and electron transport

2nd stage: The Krebs cycle is named after Hans Krebs,

the British biochemist who demonstrated its existence in 1937.  

During the Krebs cycle, pyruvic acid is broken down into carbon dioxide in a series of energy-extracting reactions.

Then….

  The electron transport chain uses the high-energy electrons from the Krebs cycle…. to convert ADP into ATP.

See video http://www.biologyinmotion.com/atp/

index.html

Aerobic vs Anaerobic Resp

Aerobic- oxygen needed to make ATP Krebs cycle

An-aerobic- fermentation Lactic acid alcoholic

How much energy is in food

Food energy is measured in calories Food is for

Chemical building blocks for bodies Raw materials for new molecules Energy

1 gram of glucose= 3811 calories of heat energy…… WOW???!!!!!!

WOW???!!!

On the label, foods are actually in kilocalories not calories

1000 calories- 1 kilocalorie Hershey kiss= 22 kilo-calories REALLY

(22,000 calories)-

Calorimeter

Calorie- amount of energy needed to raise the temperature of 1 gram of water , up 1 degree Celsius

How efficient is the process of cellular respiration? The 36 ATP molecules the cell makes per

glucose represent about 38 percent of the total energy of glucose.

That might not seem like much, but it means that the cell is actually more efficient at using food than the engine of a typical automobile is at burning gasoline.

What happens to the remaining 62 percent? It is released as heat, which is one of the reasons your body feels warmer after vigorous exercise

Equation for Respiration

Observations?

The formula for aerobic cellular respiration is C6H12O6 + O2 → CO2 + H2O + Energy (as

ATP)

The word equation for this is: Glucose + Oxygen → Carbon dioxide + Water +

Energy (as ATP)

Photosynthesis vs. Respiration

Study the relationships between the 2

Creatine (GNC- Vitamin Shoppe)

Creatine Phosphate Occurs naturally in muscle cells Contains reserve of energy Its P- group can be removed to

make more ATP, from ADP, when there is a short supply

Will help to sustain intense activity longer

*** Can cause kidney damage though, if used improperly…

Start race (1 sec – 10 sec)

11 sec- 90 sec

ATP already in muscles (STORED- only lasts a few seconds)

ATP from fermentation (90 seconds or 50 meters)

Steady pace (2min-19 min) ATP from Cell Resp…. energy in muscle and tissues: “carbohydrate glycogen”, lasts for 15 or 20 min.

Steady Pace (20 min +) Stored molecules (fat) used (as energy supply

End race Breathe deeply to remove lactic acid- extra oxygen needed

Energy and ExerciseBang! The starter's pistol goes off, and the runners push off their starting blocks and sprint down the track. The initial burst of energy soon fades, and the runners settle down to a steady pace. After the runners hit the finish line, they walk around slowly and breathe deeply to catch their breath.Let's look at what happens at each stage of the race in terms of the pathways the body uses to release energy. To obtain energy, the body uses ATP already in muscles and new ATP made by lactic acid fermentation and cellular respiration. At the beginning of a race, the body uses all three ATP sources, but stored ATP and lactic acid fermentation can only supply energy for a limited

time.Quick Energy What happens when your body needs lots of energy in a hurry? In response to sudden danger, quick actions might make the difference between life and death. To an athlete, a sudden burst of speed might win a race.Cells normally contain small amounts of ATP produced during glycolysis and cellular respiration. When the starting gun goes off in a footrace, the muscles of the runners contain only enough of this ATP for a few seconds of intense activity. Before most of the runners have passed the 50-meter mark, that store of ATP is nearly gone. At this point, their muscle cells are producing most of their ATP by lactic acid fermentation. These sources can usually supply enough ATP to last about 90 seconds. In a 200- or 300-meter sprint, this may be just enough to reach the finish line.Fermentation produces lactic acid as a byproduct. When the race is over, the only way to get rid of lactic acid is in a chemical pathway that requires extra oxygen. For that reason, you can think of a quick sprint building up an oxygen debt that a runner has to repay after the race with plenty of heavy

breathing.Long-Term Energy What happens if a race is longer? How does your body generate the ATP it needs to run 2 kilometers or more, or to play in a soccer game that lasts more than an hour? For exercise longer than about 90 seconds, cellular respiration is the only way to generate a continuing supply of ATP. Cellular respiration releases energy more slowly than fermentation, which is why even well-conditioned athletes have to pace themselves during a long race or over the course of a game. Your body stores energy in muscle and other tissues in the form of the carbohydrate glycogen. These stores of glycogen are usually enough to last for 15 or 20 minutes of activity. After that, your body begins to break down other stored molecules, including fats, for energy. This is one reason why aerobic forms of exercise such as running, dancing, and swimming are so beneficial for weight control.