1999 triazole derivatives

triazole derivativesR 0280

48 - 142An Efficient Synthesis of 3-Trifluoromethylated 1,2,4-TriazoliumSalts. — An experimentally simple, convenient entry to CF3-containing1,2,3,5-tetrasubstituted 1,2,4-triazolium salts, which are not readily accessibleby other methods, is reported. Starting from hydrazones (I) their treatmentwith tBuOCl gives azo compounds (II), which under treatment with nitrilesand SbCl5 produce the target salts (11 examples) via trifluoromethylated1-aza-2-azoniaallene salts as reactive intermediates. — (LIU, XIANJUN; ZOU,JIANPING; FAN, YUBO; WANG, QUANRUI; Synthesis (1999) 8, 1313-1318;Dep. Chem., Fudan Univ., Shanghai 200433, Peop. Rep. China; EN)

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