2001 reduction, hydrogenation

reduction, hydrogenationO 0220

37 - 064Chemoselective Control of Hydrogenation Among Aromatic Car-bonyl and Benzyl Alcohol Derivatives Using Pd/C(en) Catalyst. —Employing a heterogeneous Pd/ethylenediamine complex catalyst possessingless catalytic activity than the commercial Pd-C catalyst, the chemoselectivehydrogenation of various aromatic carbonyl compounds to benzyl alcoholsis achieved and the complete conversion to the corresponding methylenederivatives is avoided. In addition, this catalyst is used in the chemoselectivedeacetoxylation reaction at the benzylic position in the presence of a benzyl al-cohol functionality within the molecule. — (HATTORI, KAZUYUKI; SAJIKI,HIRONAO; HIROTA, KOSAKU; Tetrahedron 57 (2001) 23, 4817-4824; Lab.Med. Chem., Gifu Pharm. Univ., Mitahora, Gifu 502, Japan; EN)

1