1999 stereochemistry

stereochemistry (general, optical resolution)O 0030

10 - 038Enantioselective Claisen Rearrangement of Difluorovinyl Allyl Ethers.— The enantioselective Claisen rearrangement of the title ethers is achieved,for the first time, in moderate to good enantioselectivity using a chiral boronreagent as the Lewis acid. The direction of the asymmetric induction isdetermined by the double bond geometry. — (ITO, HISANAKA; SATO,AZUSA; KOBAYASHI, TETSUO; TAGUCHI, TAKEO; Chem. Commun.(Cambridge) (1998) 22, 2441-2442; Tokyo Univ. Pharm. Life Sci., Hachioji,Tokyo 192-03, Japan; EN)

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