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200915.fm Seite 53 Montag, 16. März 2009 11:49 11

DeprotectionO 0345 Novel Practical Deprotection of N-Boc Compounds Using Fluorinated Alcohols.

— A selective deprotection of 2 Boc groups is achieved using trifluoroethanol or hexa-fluoroisopropanol as solvents. The mild conditions are compatible with a variety of pro-tecting groups. — (CHOY, J.; JAIME-FIGUEROA*, S.; JIANG, L.; WAGNER, P.; Synth. Commun. 38 (2008) 21, 3840-3853; Roche, Palo Alto, CA 94304, USA; Eng.) — K. Woydowski

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