2008

Polyphenyl derivativesQ 0700 Palladium-Catalyzed Suzuki—Miyaura Cross-Coupling of Various Aryl Halides

Using ortho-Alkyl-Substituted Arylphosphanes and (ortho-Alkylphenyl)-alkyl-phosphanes under Microwave Heating. — Palladium-catalyzed Suzuki—Miyaura cross coupling of a wide range of aryl halides (I) with phenyl- or 2-biphenylboronic acid (II) proceeds with constantly high yields in the presence of (o-isopropylphenyl)di-isopropylphosphine ligand. In contrast to triphenylphosphine ligand, even unreactive aryl chlorides as well as sterically hindered aryl halides provide excellent yields with the novel dialkylarylphosphine ligand. — (VUOTI*, S.; AUTIO, J.; LAITILA, M.; HAUKKA, M.; PURSIAINEN, J.; Eur. J. Inorg. Chem. 2008, 3, 397-407; Dep. Chem., Univ. Oulu, SF-90570 Oulu, Finland; Eng.) — Mischke

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