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Quinoline derivativesR 0410 DOI: 10.1002/chin.201042144
Synthesis and Biological Evaluation of New 2-Chloro-3-((4-phenyl-1H-1,2,3-tri-azol-1-yl)methyl)quinoline Derivatives via Click Chemistry Approach. — New quinoline derivatives (III) are synthesized via 1,3-dipolar cycloaddition in terms of a click chemistry approach. All synthesized substances are screened for their antibacte-rial and antifungal activity. Most of the tested compounds show significant potency. (IIIc) and (IIId) are similarly active against Bacillus subtilis and Escherichia coli as streptomycin. — (KATEGAONKAR, A. H.; SHINDE, P. V.; KATEGAONKAR, A. H.; PASALE, S. K.; SHINGATE, B. B.; SHINGARE*, M. S.; Eur. J. Med. Chem. 45 (2010) 7, 3142-3146, DOI:10.1016/j.ejmech.2010.04.002 ; Dep. Chem., Marathwada Univ., Aurangabad 431 004, India; Eng.) — H. Haber
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ChemInform 2010, 41, issue 42 © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim