CME QUESTIONS FOR JUNE 2004 ISSUE OFTHE JOURNAL OF UROLOGY�

1. ROLE OF ANDROGENS IN ERECTILE FUNCTION (vol. 171, pp. 2358–2362)

Testosterone influences sexual function modulation at the:

a) central levelb) central and peripheral levelsc) peripheral leveld) no influence

2. SAFETY AND EFFICACY OF PARTIAL NEPHRECTOMY FOR ALL T1 TUMORS BASED ON ANINTERNATIONAL MULTICENTER EXPERIENCE (vol. 171, pp. 2181–2185)

Which answer is correct?

a) the historically accepted cutoff size for tumors treated with partial nephrectomy is 7 cmb) studies have demonstrated that improved cancer specific survival rates can be achieved when treating T1b tumorswith radical rather than partial nephrectomyc) partial nephrectomy for T1a and T1b tumors demonstrates a greater rate of local recurrence than radicalnephrectomy for the same indicationd) T1b tumors recur more often than T1a tumors following partial nephrectomye) cancer specific survival with T1a tumors is higher than with T1b tumors, regardless of the method of surgicaltreatment

3. BICALUTAMIDE 150 MG MAINTAINS BONE MINERAL DENSITY DURING MONOTHERAPY FOR LOCALIZEDOR LOCALLY ADVANCED PROSTATE CANCER (vol. 171, pp. 2272–2276)

The preservation of bone density in men treated with bicalutamide is mediated by:

a) increased absorption of calciumb) increased levels of testosteronec) increased levels of estrogend) decreased levels of parathyroid hormonee) improved muscle mass stimulated by bicalutamide

4. A SINGLE IMMEDIATE POSTOPERATIVE INSTILLATION OF CHEMOTHERAPY DECREASES THE RISK OFRECURRENCE IN PATIENTS WITH STAGE Ta T1 BLADDER CANCER: A META-ANALYSIS OF PUBLISHEDRESULTS OF RANDOMIZED CLINICAL TRIALS (vol. 171, pp. 2186–2190)

One immediate instillation of chemotherapy after transurethral resection:

a) is excessive treatment for patients with a single low risk tumorb) is recommended for patients with multiple tumors before additional adjuvant treatmentc) reduces the risk of progression to muscle invasive diseased) results in increased overall costse) given within 24 hours after transurethral resection results in an increased risk of toxicity

5. TROSPIUM CHLORIDE IMPROVES OVERACTIVE BLADDER SYMPTOMS: A MULTICENTER PHASE III TRIAL(vol. 171, pp. 2311–2315)

Trospium chloride:

a) reduces stress incontinenceb) is selective for receptors in the human detrusorc) has no known drug-drug interactionsd) produces active metabolites which reduce incontinence

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