Cofactor Binding Motifs

-Electron/proton Transport, An evolutionary conservation of keycofactors in a highly conserved function

-Adenosine(Nucleotide) binding Motifs

-Flavin binding motifs

-Coenzyme B12 binding/radical catalysis and the TIM Barrel

-Heme binding motifs (Recent motifs in biosensing.)

Electron Transport,Archaea to Man

Scahfer et al. FEMS 18 p.173-188

Electron Transport - Archaea to Man

Electron Transport - Archaea to Man

Electron Transport - Archaea to Man

Electron Transport - Archaea to Man

The Bateman Domain

p. 274

CBS Domain

The Bateman Domain (cont.)

The Bateman Domain (cont.)

The Bateman Domain (cont.)

The Bateman Domain (cont.)

The Bateman Domain (cont.)

The Bateman Domain (cont.)

The Bateman Domain (cont.)

The Bateman Domain (cont.)

Adenosine (Nucleotide) Binding Motifs

Schmitt et al. J. Mol. Bio. 330 p.333-342

ATP (Nucleotide) Binding Motifs

ATP (Nucleotide) Binding Motifs

ATP (Nucleotide) Binding Motifs

Dinucleotide Binding Motifs – The Rossman Fold

The Modified Rossman Fold

The Modified Rossman Fold

Flavin Binding Motifs

Flavin Binding Domains are Modular

Flavin Domain

Lactase Domain

Flavin Binding Motifs

Flavin Binding Motifs

Heme Binding Motifs - Biosensors

Heme Binding Motifs - Biosensors

Heme Binding Motifs - Biosensors

Heme Binding Motifs - Biosensors

Heme Binding Motifs - Biosensors

Other Heme Binding Motifs - Three Over ThreeAnd Two Over Two

Biochemistry and Molecular Biology Education 29 (2001) 123–125

Other Heme Binding Motifs - Photoplexin

Other Heme Binding Motifs - Photoplexin

Other Heme Binding Motifs - Photoplexin

Crenell et al. FEMS 191 p.139-144

Other Heme Binding Motifs - Photoplexin

Pro2

His77

Mono

Stereo

Fobs-Fcalc Omit map for Pro 1, 2 and the heme group of CooA

Femtomolar NO Sensor from Clostridium botulinium

Noiche et al. Science Express (To be published)