Cosmeceutical - Definition and Photoaging

8/11/2019 Cosmeceutical - Definition and Photoaging

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GROUP VIICosmeceuticalsDefinitions and Photoaging


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In the United States, according to the FDC act of 19cosmetic is defined as an article intended to be rubpoured, sprinkled, or sprayed on, introduced intotherwise applied to the human body or any part thfor cleansing, beautifying, promoting attractivenealtering the appearance without affecting structufunction of the body.

Definition


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In Europe, the definition of a cosmetic was reevaluand described by the council directive 93/35/EEC of 14th, 1993. A cosmetic product shall mean substance or preparation intended to be placecontact with the various external parts of the human epidermis, hair system, nails, lips and external gorgans or with the teeth and the mucous membranthe oral cavity with a view exclusively or mainly to clethem, perfuming them, changing their appearand/or correcting body odours and/or protecting thekeeping them in good condition.

Definition


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According to the pharmaceutical affairs law,Japanese definition of a cosmetic is as follows: The cosmetic means any article intended to be usemeans of rubbing, sprinkling or by similar application thuman body for cleansing, beautifying, promattractiveness and altering appearance of the hubody, and for keeping the skin and hair healthy, provthat the action of the article on the human body is mi

Definition


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Cosmeceuticals could be characterized as follows: The product has pharmaceutical activity and can be us

normal or near-normal skin. The product should have a defined benefit for minor skin dis

(cosmetic indication). As the skin disorder is mild the product should have a very l

profile

Definition


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Definition


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The term cosmeceutical implies cosmetic utility with aactivity of at least a mild pharmacological orpharmaceutical nature.

Intrinsic aging of the skin The terms photoaging and photodamage

Photoaging


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Subjects self-perceptions Customer cosmetic expectations Product physical attributes Regulatory aspects Marketing claims Degree of pharmacological activity

PhotoagingThe Cosmeceutical Perspective


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Photoaging Signs and Symptoms Overall appearance older than chronological age Wrinkles, fine and coarse Diverse pigmentary alterations Rough texture Dryness Sallow complexion Various neoplasms, benign and malignant

Clinical Condition of PhotoagingCosmetic Deficits


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Functional Abnormalities of Photoaging Uneven tanning Skin easily distends Slow return to normal contour Thinned skin easily traumatized Sensory decrease Decrease in immune competence

Clinical Condition of PhotoagingClinical Presentations


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Photodamage-related structural alterations in epidermand dermis

Sensory decrease A decrease in immune competence of aged skin

Clinical Condition of PhotoagingFunctional Alterations


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Product attributes

Cosmeceutical Testing

Claim Substantiation

Use of Instrumentation

Cosmeceutical Product Testing


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Product qualities and potential acceptance can be tby using panel below of the formulations : Product attributes by dermatosensory panel

Claim substantiation

Instrumentation

Pharmaceutical testing

Cosmeceutical Product TestingProduct Attributes


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Optical profilometry Fluorescent photography Ultrasound Transepidermal water loss Skin hydration by capacitance/conductance Laser Doppler

Colorimetry

Cosmeceutical Product TestingUse of Instruments


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Most of the below products described are potentialcosmeceuticals, many as pharmacologically active, amost as cosmeceutical Moisturizer

Retinoids

Estrogens

Various vitamins and minerals

Alpha-hydroxy acids Beta-hydroxy acids

Hydroquinones

Hyaluronic acid

Natural cartilage polysaccharides

Products Potentially Classed AsCosmeceuticals


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Sar i F i t r ianiRudiarf iansyahFitr i Aqmalia

SutoyoSurya NengsiDjumarni F i rmanIsmul Azham Ridwan

Group VII

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Cosmeceutical - Definition and Photoaging