fdlGrades UO_SCCHM3004_2016/20_2016-07-18 16:09:35 CRICOS Provider Number: 00103D 1 /3

Course Outline

School / Portfolio: Faculty of Science and Technology

Course Title: ORGANIC SYNTHESIS FOR DRUG DESIGN

Course ID: SCCHM3004

Credit Points: 15.00

Prerequisite(s): (CHMGC2922 or SCCHM2001)

Co-requisite(s): Nil

Exclusion(s): (CHMGC2762 and SCCHE2002)

ASCED Code: 010501

Program Level:

AQF Level of Program 5 6 7 8 9 10

LevelIntroductoryIntermediateAdvanced

Learning Outcomes:

Knowledge:

K1. Apply the key concepts of chemical structure and bonding to an understanding of reactivity oforganic molecules and intermediates;

K2. Discuss the reactivity of organic functional groups and write equations for common reactions ofalcohols, alkenes, alkyl halides, aromatic compounds, carbonyl compounds, carboxylic acids andtheir derivatives and organometallic compounds;

K3. Describe the mechanisms of substitution and elimination reactions and predict the conditionswhich favour these reactions;

Skills:

S1. Predict the products of a range of organic reactionsS2. Demonstrate problem solving skills and ability to work both independently and in small groupsS3. Design and undertake organic synthesis in the laboratory and use modern instrumental

techniques to identify and characterize products

Application of knowledge and skills:

A1. Suggest reaction pathways and favourable conditions for the synthesis of simple organicmolecules from readily available materials and design and undertake these syntheses in thelaboratory

Course Content:

fdlGrades UO_SCCHM3004_2016/20_2016-07-18 16:09:35 CRICOS Provider Number: 00103D 2 /3

Course OutlineSCCHM3004 ORGANIC SYNTHESIS FOR DRUG DESIGN

In this course, students will study the structure, synthesis, reactivity and analysis of simple organicmolecules with a focus on pharmaceuticals and bio-chemicals.

Topics may include:

Reactive intermediates and molecular rearrangements,Elimination reactions from alkenes,Nucleophilic substitution and elimination,Aromatic and heterocyclic chemistry,Carbonyl compounds and their derivativesOrganometallics

Values and Graduate Attributes:

Values:

V1. In this course, students will continue to develop an inquiring and curious attitude to science.V2. Students will have the opportunity to collaborate with others in solving authentic synthetic

problems.V3. As they work through the content students will continue to acquire the ability for reflective, life-

long learning.

Graduate Attributes:

Attribute Brief Description Focus

Continuous LearningStudents will be encouraged to reflect on their learning in thisclass. Feedback provided on assessment tasks will allowstudents to improve their scientific writing.

High

Self Reliance Students will work independently and in groups within thelaboratory environment Medium

Engaged Citizenship Students will be exposed to real-world examples of drugdesign. Medium

Social ResponsibilityExamples and case-studies which reflect the ethical andsocial responsibilities of synthetic chemists will be explored inthis course.

Low

Learning Task and Assessment:

LearningOutcomesAssessed

Assessment Task Assessment Type Weighting

K1, K2, K3, S1, S2,A1

Weekly tutorial/online assessmentsincluding short answer questions, synthesisproblems, application of key chemicalconcepts to rectivity

Weekly tutorial/onlineassessment problems 20-30%

S1, S2, S3 Design and carry out organic synthesis inthe laboratory

Laboratory performanceand written reports 20-30%

K1, K2, K3, S1, S2,A1

Short answer questions, synthesisproblems, application of key chemicalconcepts to reactivity

Written examination (3hours) 50-60%

Adopted Reference Style:

fdlGrades UO_SCCHM3004_2016/20_2016-07-18 16:09:35 CRICOS Provider Number: 00103D 3 /3

Course OutlineSCCHM3004 ORGANIC SYNTHESIS FOR DRUG DESIGN

Australian