CURRICULUM VITAE

NAME Ertugrul KilicSEX MaleBIRTHDATE 19 March 1971NATIONALITY TurkishMARITAL STATUS Married, one daughterADRESS Yeditepe University

Faculty of MedicineDepartment of PhysiologyTR-34755 Kayisdagi, Istanbul, TurkeyPhone: +90 216 5780419Fax: +90 216 5780575e-mail: kilic44@yahoo.comertugrul.kilic@yeditepe.edu.tr

ACADEMIC DEGREE Prof. Dr. Human PhysiologyAssoc. Prof., Human PhysiologyPhD, Human physiology, PhD, Cell Biology

LANGUAGE German and English

EDUCATION

1989- 1994 Faculty of Veterinary, University of Ankara, Ankara, Turkey

1994-1999 1. PhD in Physiology, Faculty of Medicine, University of Firat, Elazığ

1999-2002 2. PhD in Cell Biology, Eberhard-Karls-Universität, Tübingen Germany

2004 Assoc. Prof. in Human Physiology, Turkey

2010 Full Professor

POST-GRADUATE WORKS

1

1994-1997 May Research assistant in Department of Pharmacology and Physiology, Faculty of Medicine, University of Inönü, Malatya, Turkey

1997 May-1997 Dec Research Fellow in Brain Research Laboratory, Department of Neurology, Hacettepe University, Ankara, Turkey

1997 Dec-1998 July Research Fellow in Max-Planck-Institute for Neurological Research, Department of Experimental Neurology, Cologne, Germany.

1998 Nov-1999 March Research Fellow in Focal Brain Ischemia Laboratory, Department of Neurology, University of Tübingen, Germany

1999 March-1999 Nov Postdoc Research Fellow in Focal Brain Ischemia Laboratory, Department of Neurology, University of Tübingen, Germany

1999 Nov-2001 July Postdoc Research Fellow in Brain Research Laboratory, Neurology University of Tübingen, Germany

2001 Aug-2002-Dec Senior researcher in Brain Research Laboratory, Neurology University of Göttingen, Germany

2002 Dec- 2008-Apr Senior researcher in National Center of Competence in Research, Neural Plasticity and Repair, Brain Research laboratory, Neurology, University of Zürich, Switzerland.

2008 Apr- Assoc. Prof. Dr. University of Yeditepe, Faculty of MadicineDepartment of Physiology, Istanbul, Turkey

AWARDS

1996 June-Aug Scholarship from DAAD, Germany

1997 Dec-1998 july Scholarship from Scientific and Technical ResearchCouncil of Turkey (TÜBITAK)

1998 Nov 1999Nov Scholarship from the Federal Ministry of Education, Science, Research and Technology and Interdisciplinary Center of Clinical Research. (IKFZ) University of Tübingen, Germany

1998 Sep Posterpreis in 34. National Neurology congress in Turkey 1999 Sep Posterpreis in 25. National Physiology congress in Turkey

2000 July Young scientist support in 8. international Syposium on Pharmacology of Cerebral Ischemia. Marburg, Germany

2000 Oct Young scientist support in III. Neurobiology Conference, Molecular and Cellular Mechanisms of Brain Repair, Torino Italy

2003 May Posterpreis in der Klinischen Forschung am UniversitätsSpital Zürich, Schweiz

2005 March Poster and oral presentation price (in der Klinischen Forschung am UniversitätsSpital Zürich, Schweiz)

2005 March Young scientist travel support in ENS meeting Austria

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2005 June Bursary, Brain 05, Amsterdam, Netherlands (16/04/2005-31/05/2005)

2005 Sep Bursary, 9th EFNS (European Federation of Neurological Societies) Congress

2006 March Hartmann Müller-Foundation, Zurich, Switzerland (45.000.00 CHF)

2006 October Franco Regli Price, Interlaken (An annual neuroscience price nominated by Prof. Dr. Franco Regli and Prof. Dr. Pierre Magistretti) (7.500 CHF)

2008 Nov EMBO installation grant

2009-Oct Junior Chamber International, The Outstanding Young Person Award in Medical Innovation

2010-April 9th National neuroscience meeting the best poster price

2010 April 9th National neuroscience meeting poster price

Membership in Professional SocietiesInternational Society for Cerebral blood Flow and MetabolismBrain Research Society, Turkey

Editorial Advisory Board Member1-The Open Nitric Oxide Journalhttp://www.bentham.org/open/tonoj/EBM.htm

2-The Open Enzyme Inhibition Journalhttp://www.bentham.org/open/toeij/EBM.htm

3-The Open Bioactive Compounds Journalhttp://www.bentham.org/open/tobcj/EBM.htm

4- Cell Membranes and Free Radical Researchhttp://www.cmostr.org/editors.htm

Ad hoc reviewer Acta Pharmacologica Sinica, American Journal of Cardiology, Anadolu Kardiyoloji Dergisi, Annals of Neurology, Apoptosis, Archives of Medical Research, Atherosclerosis, Biological Psychiatry, BMC Neurology, Brain Research, Brain Research Bulletin, Cell Biochemistry & Function, Cell Death and Differentiation, Cellular and Molecular Neurobiology, Cellular and Molecular Life Science, CEPP, Circulation, Clinical Chemistry and Laboratory Medicine, CNS Neuroscience & Therapeutics, European Cytokine Network, European Journal of Epilepsy, Experimental Neurology, Experimental Brain Res., Expert Review of Neurotherapeutics, Fırat Üniversitesi Sağlık Bilimleri Dergisi, J. Cellular Physiology, Journal of Cerebral Blood Flow and Metabolism, Journal of Membrane Biology, J. Neurochemistry, J. Neural Transmission, J. Neuroscience Research, J. Pharmacology, J. Pineal Research, Neurobiology of Disease, Neurological Research, Neuroscience, Neuroscience letters, The Tohoku Journal of Experimental Medicine, Turkish Journal of Medical Sciences, Stroke

TraineesJens Weise, Burak Yulug, Yvonne Jeger, Raoul Sander, Olaf Crome, Ulkan Kilic, Ertugrul Cam, Anett Spudich, Yoaming Wang, Hongyi Xing, Zhu Wang, Marco Bacigalluppi, Engin Sahna, Zeyun Guo, Ayman El Ali, Anil Zechariah.

Courses attended:

3

LTK: (http://www.ltk.unizh.ch)

1. ``Generation of Transgenic Mice`` LTK Modul 3

2. ``Molecular Basis for the Work with Transgenic Animals`` LTK Module15E

3. ``Genetic Breeding Testing methods in mice`` LTK Modul 5

4. ``In-vitro Culture of Embryonic cells and Primer cells`` LTK Modul 6

5. ``Production of polyclonal and monoclonal antibodies`` LTK Modul 8

6. ``Basic Electrophysiology``, University of Zurich, Dept. of Physiology, Zürich, April 2006

7. ``Didactic course for Lecturers`` University of Zurich, Faculty of Medicine, Deanery, Zürich, 15-16. October 2004

A- PhDs

1. PhD: Effects of pinealectomy and melatonin on the focal cerebral ischemia in rats. 2. PhD: Effects of tat fusion protein- and adenovirus-mediated Bcl-XL delivery on ischemic brain injury.

B- Publications (April 2010, Citations: 1450; H index: 22).

1. Kilic, E., ElAli, A., Kilic, U., Guo, Z., Ugur, M., Uslu, U., Bassetti, C.L., Hermann, D.M. Role of Nogo-A in neuronal survival in the reperfused ischemic brain (2010) Journal of Cerebral Blood Flow and Metabolism,  Article in Press. (I.F.: 5.741)

2. Yulug B, Ozan E, Kilic E.

Brain-derived neurotrophic factor polymorphism as a genetic risk for depression? A short review of the literature.(2010) J Neuropsychiatry Clin Neurosci. Winter;22(1):123d.e5-123.e6. (I.F.: 2.362)

3. Sahin K, Akdemir F, Tuzcu M, Sahin N, Onderci M, Ozercan R, Ilhan N, Kilic E, Seren S, Kucuk O.

Genistein suppresses spontaneous oviduct tumorigenesis in quail.(2009) Nutr Cancer. 2009 Nov;61(6):799-806. (I.F.: 2.360)

4. Yalvac, M.E., Rizvanov, A.A., Kilic, E., Sahin, F., Mukhamedyarov, M.A., Islamov, R.R., Palotás, A.Potential role of dental stem cells in the cellular therapy of cerebral ischemia (2009) Current Pharmaceutical Design, 15 (33), pp. 3908-3916. (I.F.: 4.399)

5. Yulug, B., Kilic, E.Olanzapine does not aggrevate ischemic neuronal injury by focal cerebral ischemia: A dose related restriction of the neuroprotective effect? (2009) Medicinal Chemistry, 5 (3), pp. 279-282. (I.F.: 2.362)

6. Bacigaluppi, M., Martino, G., Hermann, D.M., Pluchino, S., Jametti, L.P., Kilic, E., Kilic, Ü., Comi, G.Delayed post-ischaemic neuroprotection following systemic neural stem cell transplantation involves multiple mechanisms (2009) Brain, 132 (8), pp. 2239-2251.

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7. Aydin, O., Kahraman, M., Kilic, E., Çulha, M.Surface-enhanced raman scattering of rat tissues (2009) Applied Spectroscopy, 63 (6), pp. 662-668. (I.F.: 2.062)

8. Yulug, B., Ozan, E., Gönül, A.S., Kilic, E.Brain-derived neurotrophic factor, stress and depression: A minireview (2009) Brain Research Bulletin, 78 (6), pp. 267-269. (I.F.: 2.281)

9. Hermann, D.M., Kilic, E.Therapeutic potential and possible risks of pleiotropic growth factors in ischemic stroke (2008) Stroke, 39 (11), p. e182. (I.F.: 6.499)

10. Cam, E., Yulug, B., Cengiz, N., Poelkin, E., Isýk, D., Bakar, M., Ozan, E., Kilic, E.Melatonin: A suitable agent for depression associated with stroke? (2008) Journal of Neuropsychiatry and Clinical Neurosciences, 20 (4), pp. 498-500. (I.F.: 2.362)

11. Kilic, E., Hermann, D.M., Spudich, A., Kilic, Ü., Rentsch, K.M., Vig, R., Matter, C.M., Bassetti, C.L.ABCC1: A gateway for pharmacological compounds to the ischaemic brain (2008) Brain, 131 (10), pp. 2679-2689. (I.F.: 9.603)

12. Gao, B., Kilic, E., Baumann, C.R., Hermann, D.M., Bassetti, C.L.Gamma-hydroxybutyrate accelerates functional recovery after focal cerebral ischemia (2008) Cerebrovascular Diseases, 26 (4), pp. 413-419. (I.F.: 3.041)

13. Kilic, E., Kilic, U., Bacigaluppi, M., Guo, Z., Abdallah, N.B., Wolfer, D.P., Reiter, R.J., Bassetti, C.L.Delayed melatonin administration promotes neuronal survival, neurogenesis and motor recovery, and attenuates hyperactivity and anxiety after mild focal cerebral ischemia in mice (2008) Journal of Pineal Research, 45 (2), pp. 142-148. (I.F.: 5.056)

14. Kilic, U., Kilic, E., Matter, C.M., Bassetti, C.L., Hermann, D.M.TLR-4 deficiency protects against focal cerebral ischemia and axotomy-induced neurodegeneration (2008) Neurobiology of Disease, 31 (1), pp. 33-40. (I.F.: 4.852)

15. Bacigaluppi, M., Pluchino, S., Martino, G., Kilic, E., Hermann, D.M.Neural stem/precursor cells for the treatment of ischemic stroke (2008) Journal of the Neurological Sciences, 265 (1-2), pp. 73-77. (I.F.: 2.359)

16. Hédou, G.F., Koshibu, K., Farinelli, M., Kilic, E., Gee, C.E., Kilic, U., Baumgärtel, K., Mansuy, I.M.Protein phosphatase 1-dependent bidirectional synaptic plasticity controls ischemic recovery in the adult brain (2008) Journal of Neuroscience, 28 (1), pp. 154-162. (I.F.: 7.452)

17. Kilic, E., Hermann, D.M., Wippel, A., Kilic, Ü., Vogel, P., Kim, M., van der Putten, H., Böttiger, B.W.Poxvirus-derived cytokine response modifier A (CrmA) does not protect against focal cerebral ischemia in mice (2007) Brain Research, 1185 (1), pp. 293-300. (I.F.: 2.494)

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18. Yulug, B., Cam, E., Yildiz, A., Kilic, E.Buprenorphine does not aggrevate ischemic neuronal injury in experimental focal cerebral ischemia (2007) Journal of Neuropsychiatry and Clinical Neurosciences, 19 (3), pp. 331-334. (I.F.: 2.362)

19. Kilic, Ü., Hermann, D.M., Kilic, E., Järve, A., Guo, Z., Spudich, A., Bieber, K., Marti, H.H.Human vascular endothelial growth factor protects axotomized retinal ganglion cells in vivo by activating ERK-1/2 and Akt pathways (2006) Journal of Neuroscience, 26 (48), pp. 12439-12446. (I.F.: 7.452)

20. Hermann, D.M., Kilic, E., Spudich, A., Krämer, S.D., Wunderli-Allenspach, H., Bassetti, C.L.Role of drug efflux carriers in the healthy and diseased brain (2006) Annals of Neurology, 60 (5), pp. 489-498. (I.F.: 9.935)

21. Baumann, C.R., Kilic, E., Petit, B., Werth, E., Hermann, D.M., Tafti, M., Bassetti, C.L.Sleep EEG changes after middle cerebral artery infarcts in mice: Different effects of striatal and cortical lesions (2006) Sleep, 29 (10), pp. 1339-1344. (I.F.: 4.475)

22. Kilic, E., Kilic, Ü., Wang, Y., Bassetti, C.L., Marti, H.H., Hermann, D.M.The phosphatidylinositol-3 kinase/Akt pathway mediates VEGF's neuroprotective activity and induces blood brain barrier permeability after focal cerebral ischemia (2006) FASEB Journal, 20 (8), pp. E307-E314. (I.F.: 7.049)

23. Kilic, E., Kilic, U., Wang, Y., Bassetti, C.L., Marti, H.H., Hermann, D.M.The phosphatidylinositol-3 kinase/Akt pathway mediates VEGF's neuroprotective activity and induces blood brain barrier permeability after focal cerebral ischemia. (2006) The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 20 (8), pp. 1185-1187. (I.F.: 7.049)

24. Yulug, B., Yildiz, A., Güzel, O., Kilic, E., Schäbitz, W.R., Kilic, E.Risperidone attenuates brain damage after focal cerebral ischemia in vivo (2006) Brain Research Bulletin, 69 (6), pp. 656-659. (I.F.:2.281)

25. Spudich, A., Kilic, E., Xing, H., Kilic, Ü., Rentsch, K.M., Wunderli-Allenspach, H., Bassetti, C.L., Hermann, D.M.Inhibition of multidrug resistance transporter-1 facilitates neuroprotective therapies after focal cerebral ischemia (2006) Nature Neuroscience, 9 (4), pp. 487-488. (I.F.: 14.164)

26. Kilic, E., Kilic, U., Hermann, D.M.TAT fusion proteins against ischemic stroke: Current status and future perspectives (2006) Frontiers in Bioscience, 11 (2), pp. 1716-1721. (I.F.: 3.308)

27. Kilic, E., Kilic, Ü., Soliz, J., Bassetti, C.L., Gassmaim, M., Hermann, D.M.Brain-derived erythropoietin protects from focal cerebral ischemia by dual activation of ERK-1/-2 and Akt pathways (2005) FASEB Journal, 19 (14), pp. 2026-2028. (I.F.: 7.049)

28. Kilic, E., Kilic, Ü., Hermann, D.M.TAT-GDNF in neurodegeneration and ischemic stroke (2005) CNS Drug Reviews, 11 (4), pp. 369-378. (I.F.: 4.432)

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29. Kilic, E., Kilic, Ü., Bähr, M., Hermann, D.M.Tissue plasminogen activator-induced ischemic injury is reversed by NMDA antagonist MK-801 in vivo (2005) Neurodegenerative Diseases, 2 (2), pp. 49-55. (I.F.: 2.989)

30. Spudich, A., Frigg, R., Kilic, E., Kilic, U., Oesch, B., Raeber, A., Bassetti, C.L., Hermann, D.M.Aggravation of ischemic brain injury by prion protein deficiency: Role of ERK-1/-2 and STAT-1

(2005) Neurobiology of Disease, 20 (2), pp. 442-449. (I.F.: 4.852)

31. Kilic, E., Kilic, Ü., Reiter, R.J., Bassetti, C.L., Hermann, D.M.Tissue-plasminogen activator-induced ischemic brain injury is reversed by melatonin: Role of iNOS and Akt (2005) Journal of Pineal Research, 39 (2), pp. 151-155. (I.F.: 5.056)

32. Kilic, Ü., Bassetti, C.L., Kilic, E., Xing, H., Wang, Z., Hermann, D.M.Post-ischemic delivery of the 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor rosuvastatin protects against focal cerebral ischemia in mice via inhibition of extracellular-regulated kinase-1/-2 (2005) Neuroscience, 134 (3), pp. 901-906. (I.F.: 3.556)

33. Grimm, C., Hermann, D.M., Bogdanova, A., Hotop, S., Kilic, Ü., Wenzel, A., Kilic, E., Gassmann, M.Neuroprotection by hypoxic preconditioning: HIF-1 and erythropoietin protect from retinal degeneration (2005) Seminars in Cell and Developmental Biology, 16 (4-5), pp. 531-538. (I.F.: 4.528)

34. Reiter, R.J., Tan, D.-X., Leon, J., Kilic, Ü., Kilic, E. When melatonin gets on your nerves: Its beneficial actions in experimental models of stroke (2005) Experimental Biology and Medicine, 230 (2), pp. 104-117. (I.F.: 2.202)

35. Kilic, Ü., Kilic, E., Soliz, J., Bassetti, C.L., Gassmann, M., Hermann, D.M.Erythropoietin protects from axotomy-induced degeneration of retinal ganglion cells by activating ERK-1/-2 (2005) FASEB Journal, 19 (2), pp. 249-251. (I.F.: 7.049)

36. Kilic, E., Kilic, Ü., Matter, C.M., Lüscher, T.F., Bassetti, C.L., Hermann, D.M.Aggravation of focal cerebral ischemia by tissue plasminogen activator is reversed by 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor but does not depend on endothelial NO synthase (2005) Stroke, 36 (2), pp. 332-336. (I.F.: 6.499)

37. Kilic, Ü., Kilic, E., Reiter, R.J., Bassetti, C.L., Hermann, D.M.Signal transduction pathways involved in melatonin-induced neuroprotection after focal cerebral ischemia in mice (2005) Journal of Pineal Research, 38 (1), pp. 67-71. (I.F.: 5.056)

38. Wang, Y., Kilic, E., Kilic, Ü., Weber, B., Bassetti, C.L., Marti, H.H., Hermann, D.M.VEGF overexpression induces post-ischaemic neuroprotection, but facilitates haemodynamic steal phenomena (2005) Brain, 128 (1), pp. 52-63. (I.F.: 9.603)

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39. Kilic, E., Kilic, Ü., Reiter, R.J., Bassetti, C.L., Hermann, D.M.Prophylactic use of melatonin protects against focal cerebral ischemia in mice: Role of endothelin converting enzyme-1 (2004) Journal of Pineal Research, 37 (4), pp. 247-251. (I.F.: 5.056)

40. Kilic, E., Weishaupt, J.H., Kilic, Ü., Rohde, G., Yulug, B., Peters, K., Hermann, D.M., Bähr, M.The superoxide dismutase1 (SOD1) G93A mutation does not promote neuronal injury after focal brain ischemia and optic nerve transection in mice (2004) Neuroscience, 128 (2), pp. 359-364. (I.F.: 3.556)

41. Reiter, R.J., Kilic, Ü., Tan, D.-X., Gitto, E., Sainz, R.M., Mayo, J.C., Leon, J., Kilic, E.Pharmacological utility of melatonin in reducing oxidative cellular and molecular damage (2004) Polish Journal of Pharmacology, 56 (2), pp. 159-170. (I.F.: 2.167, The Pharmacological Reports)

42. Kilic, Ü., Kilic, E., Lingor, P., Yulug, B., Bähr, M.Rifampicin inhibits neurodegeneration in the optic nerve transection model in vivo and after 1-methyl-4-phenylpyridinium intoxication in vitro (2004) Acta Neuropathologica, 108 (1), pp. 65-68. (I.F.: 5.310)

43. Kilic, Ü., Kilic, E., Dietz, G.P.H., Bähr, M.The TAT protein transduction domain enhances the neuroprotective effect of glial-cell-line-derived neurotrophic factor after optic nerve transection (2004) Neurodegenerative Diseases, 1 (1), pp. 44-49. (I.F.: 2.989)

44. Kilic, E., Kilic, Ü., Yulug, B., Hermann, D.M., Reiter, R.J.Melatonin reduces disseminate neuronal death after mild focal ischemia in mice via inhibition of caspase-3 and is suitable as an add-on treatment to tissue-plasminogen activator (2004) Journal of Pineal Research, 36 (3), pp. 171-176. (I.F.: 5.056)

45. Kilic, E., Kilic, Ü., Bassetti, C.L., Hermann, D.M.Intravenously administered recombinant tissue-plasminogen activator attenuates neuronal injury after mild focal cerebral ischemia in mice (2004) NeuroReport, 15 (4), pp. 687-689. (I.F.: 1.904)

46. Yulug, B., Kilic, U., Kilic, E., Bähr, M.Rifampicin attenuates brain damage in focal ischemia (2004) Brain Research, 996 (1), pp. 76-80. (I.F.: 2.494)

47. Kilic, Ü., Kilic, E., Dietz, G.P.H., Bähr, M.Intravenous TAT-GDNF is protective after focal cerebral ischemia in mice (2003) Stroke, 34 (5), pp. 1304-1310. (I.F.: 6.499)

48. Kügler, S., Kilic, E., Bähr, M.Human synapsin 1 gene promoter confers highly neuron-specific long-term transgene expression from an adenoviral vector in the adult rat brain depending on the transduced area (2003) Gene Therapy, 10 (4), pp. 337-347. (I.F.: 4.492)

49. Kilic, E., Hermann, D.M., Kügler, S., Kilic, Ü., Holzmüller, H., Schmeer, C., Bähr, M.Adenovirus-mediated Bcl-XL expression using a neuron-specific synapsin-1 promoter protects against disseminated neuronal injury and brain infarction following focal cerebral ischemia in mice (2002) Neurobiology of Disease, 11 (2), pp. 275-284. (I.F.: 4.852)

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50. Kilic, E., Dietz, G.P.H., Hermann, D.M., Bähr, M.Intravenous TAT-Bcl-XL is protective after middle cerebral artery occlusion in mice (2002) Annals of Neurology, 52 (5), pp. 617-622. (I.F.: 9.935)

51. Dietz, G.P.H., Kilic, E., Bähr, M.Inhibition of neuronal apoptosis in vitro and in vivo using TAT-mediated protein transduction (2002) Molecular and Cellular Neuroscience, 21 (1), pp. 29-37. (I.F.: 3.934)

52. Kilic, E., Hermann, D.M., Isenmann, S., Bähr, M.Effects of pinealectomy and melatonin on the retrograde degeneration of retinal ganglion cells in a novel model of intraorbital optic nerve transection in mice (2002) Journal of Pineal Research, 32 (2), pp. 106-111. (I.F.: 5.056)

53. Hermann, D.M., Kilic, E., Kügler, S., Isenmann, S., Bähr, M.Adenovirus-mediated glial cell line-derived neurotrophic factor (GDNF) expression protects against subsequent cortical cold injury in rats (2001) Neurobiology of Disease, 8 (6), pp. 964-973. (I.F.: 4.852)

54. Kilic, E., Bähr, M., Hermann, D.M.Effects of recombinant tissue plasminogen activator after intraluminal thread occlusion in mice: Role of hemodynamic alterations (2001) Stroke, 32 (11), pp. 2641-2647. (I.F.: 6.499)

55. Dietz, G.P.H., Kilic, E., Bähr, M., Isenmann, S.Bcl-2 is not required in retinal ganglion cells surviving optic nerve axotomy (2001) NeuroReport, 12 (15), pp. 3353-3356. (I.F.: 1.904)

56. Hermann, D.M., Kilic, E., Kügler, S., Isenmann, S., Bähr, M.Adenovirus-mediated GDNF and CNTF pretreatment protects against striatal injury following transient middle cerebral artery occlusion in mice (2001) Neurobiology of Disease, 8 (4), pp. 655-666. (I.F.: 4.852)

57. Knöll, B., Isenmann, S., Kilic, E., Walkenhorst, J., Engel, S., Wehinger, J., Bähr, M., Drescher, U.Graded expression patterns of ephrin-As in the superior colliculus after lesion of the adult mouse optic nerve (2001) Mechanisms of Development, 106 (1-2), pp. 119-127. (I.F.: 2.534)

58. Hermann, D.M, Kilic, E., Hata, R., Hossmann, K.-A., Mies, G.Relationship between metabolic dysfunctions, gene responses and delayed cell death after mild focal cerebral ischemia in mice (2001) Neuroscience, 104 (4), pp. 947-955. (I.F.: 3.556)

59. Sönmez, A.S., Birincio?lu, M., Aydin, A., Kiliç, E., Şahin, N.Effects of misoprostol on the endometrium of ovariectomized rats (2000) Turkish Journal of Medical Sciences, 30 (2), pp. 115-118.

60. Kilic, E., Hermann, D.M., Hossmann, K.-A.Recombinant tissue-plasminogen adivator-induced thrombolysis after cerebral thromboembolism in mice (2000) Acta Neuropathologica, 99 (3), pp. 219-222. (I.F.: 5.310)

61. Kilic, E., Özdemir, Y.G., Bolay, H., Keleştimur, H., Dalkara, T.Pinealectomy aggravates and melatonin administration attenuates brain damage in focal ischemia

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(1999) Journal of Cerebral Blood Flow and Metabolism, 19 (5), pp. 511-516. (I.F.: 5.741)

62. Kilic, E., Hermann, D.M., Hossmann, K.-A.Recombinant tissue plasminogen activator reduces infarct size after reversible thread occlusion of middle cerebral artery in mice (1999) NeuroReport, 10 (1), pp. 107-111. (I.F.: 1.904)

63. Kilic, E., Hermann, D.M., Hossmann, K.-A.A reproducible model of thromboembolic stroke in mice (1998) NeuroReport, 9 (13), pp. 2967-2970. (I.F.: 1.904)

C- Lectures

Invited speaker and oral presentations

1. E Kilic, Role of Nogo-A in neuronal survival in the reperfused ischemic brain. 10th EMBO

Young Investigator Programme Meeting, 10-14 May 2010 Heidelberg, Germany

2. E Kilic. The Effects of Erythropoietin and VEGF on Brain Injury and Plasticity. 9. Ulusal

Sinirbilimleri Kongresi, 13-17 Nisan 2010, Istanbul

3. E Kilic . Neuroprotective Therapy Strategies After Stroke: The Roles of Intercellular Interactions, Drug Delivery and VEGF V. Ege Biennial International Neuroscience Graduate Summer School. University of Ege, June 29-July 4 2009

4. E Kilic. Neuroprotective Therapy Strategies after Brain Injury: The Roles of Drug Transporters and Vascular Endothelial Growth Factor University of Koç, Istanbul, 29 May 2009

5. E Kilic The roles of ATP-binding cassette (ABC) transporters in acute brain injury. 9th EMBO Young Investigator Programme Meeting University of Bogazici, Istanbul. 13-15 May 2009

6. E Kilic Drug Transporters and the Vascular Endothelial Growth Factor. Horizons in Molecular Biology and Genetics II. University of Bilkent, Ankara, 11-12 May 2009

7. E Kilic Neuroprotective Therapy Strategies After Stroke: Drug Delivery, Estrogen and VEGF. Neuroendocrinology symposium & Workshop, Yeditepe University, 23- 25 April 2009

8. E Kilic Nogo-A’nın beyin felci sonrasında hücre yaşamına olan etkileri, VII. Nörolojik Bilimler ve Psikiyatri Enstitüsü Günleri, Hacettepe Üniversitesi13-14 Nisan 2009

9. E Kilic Nogo-A’nın beyin felci sonrasında hücre yaşamına olan etkileri. VIII Ulusal Sinirbilimleri Kongresi ‘’Deneyden Kliniğe’’ Bolu, 18-22 Nsan 2009

10. E Kilic VEGF ve ABC tasiyicilari. 34. Fizyoloji Kongresi, Erzurum , Turkey. 6-11 Oct 2008

11. E.Kilic Melatonin a promising candidate for ischemic stroke treatment. 2nd International Congress on Cell Membranes and Oxidative Stress: Focus on Calcium Signalling and TRP Channels, 25-28 June 2008

12. E.Kilic Stroke models and pathophysiology, Mouse physiology and pathophysiology ZIHP graduate course, March 11/12, 2008

13. E Kilic Entering new avenues for stroke treatment, Department of Biology, METU, Turkey.Jan. 29.01.2008

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14. E. Kilic Entering new avenues for stroke treatment, Neuroscience Symposium, University of Erlangen, Dept. of Neurology, 5.12. 2007, Erlangen, Germany

15. E. Kilic Entering new avenues for stroke treatment, Neuroscience Symposium, 09-13 April 2007, Zonguldak, Turkey

16. E.Kilic Stroke models and pathophysiology, Mouse physiology and pathophysiology ZIHP graduate course, March 12/13, 2007

17. E.Kilic Vascular Endothelial Growth Factor and Neurodegeneration. Franco Regli Price, Interlaken 20th October 2006

18. E. Kilic. Stroke Models. Cooperation in Research and Training for European Excellence in the Neurorosciences (Cortex): Animal Models of Nervous System Diseases.17 October 2006. Irchel, Zurich

19. E. Kilic. Erholung fördern: Experimentelle Untersuchungen beim Schlaganfall Symposium im Rahmen der Besetzung einer Assistenzprofessur in Experimenteller Neurorehabilitation, 14. July 2006 Irchel, Zürich

20. E. Kilic. Experimental stroke recovery. Serono, 14th August 2006, Geneve, Switzerland

21. E. Kilic. TAT fusion proteins as innovative treatment strategy in stroke. Brain 05 (22nd International Symposium on Cerebral Blood Flow and Metabolism) in Amsterdam, Netherlands, 7.-11. Juni 2005

22. E. Kilic, U. Kilic, J. Soliz, C.L. Bassetti, M. Gassmann and D.M. Hermann. Transgenic erythropoietin protects from focal cerebral ischemia by a dual pathway involving both ERK-1/-2 and Akt. 4th day of Clinical Research, University of Zurich, Switzerland, 17./18.3.2005. Vortragspreis

23. E. Kilic. TAT fusion protein and neurodegeneration. Seminar. Neuroscience-Master students, Göttingen, Germany, 16. Dec. 2002

24. Kilic, E. Hermann, D.M. and Hossmann, K-A.. Recombinant tissue plasminogen activator reduces infarct size after reversible thread occlusion of middle cerebral artery in mice. 34. Neurology Congress, Bursa, Turkey, 23-27 Sep. 1998

25. Kilic, E. Hermann, D.M. and Hossmann, K-A. A reproducible model of thromboembolic stroke in mice.34. Neurology Congress, Bursa, Turkey, 23-27 Sep. 1998

26. A. Spudich, E. Kilic, U. Kilic, K. Rentsch, H. Wunderli-Allenspach, C.L. Bassetti and D.M. Hermann Inhibition of multidrug resistance transporter-1 facilitates neuroprotective therapies after focal cerebral ischemia. 5th Day of Clinical Research, Zentrum für Klinische Forschung, Medizinische Fakultät, Universität Zürich, Schweiz, 24. April 2006

27. A. Spudich, R. Frigg, E. Kilic, Ü. Kilic, B. Oesch, A. Raeber, C.L. Bassetti and D.M. Hermann. Aggravation of ischemic brain injury by prion protein deficiency, but lack of neuroprotection by elevated prion protein levels: Role of tyrosine kinases. 9th European Federation of Neurological Societies (EFNS), Athens, Greece, 17.-20.9.2005

28. Y. Wang, E. Kilic, Ü. Kilic, C.L. Bassetti, H.H. Marti and D.M. Hermann. Transgenic VEGF induces post-ischemic neuroprotection, but facilitates hemodynamic steal phenomena. 9th European Federation of Neurological Societies (EFNS), Athens, Greece, 17.-20.9.2005

29. Ü. Kilic, E. Kilic, J. Soliz, C.L. Bassetti, M. Gassmann and D.M. Hermann. Transgenic erythropoietin protects from focal cerebral ischemia by a dual pathway involving both ERK-1/-2 and Akt. Brain 05 (22nd International Symposium on Cerebral Blood Flow and Metabolism) in Amsterdam, Netherlands, 7.-11. Juni 2005

30. H.H. Marti, Y. Wang, E. Kilic, Ü. Kilic, C.L. Bassetti and D.M. Hermann. Transgenic VEGF induces post-ischemic neuroprotection, but facilitates hemodynamic steal phenomena. Brain 05

11

(22nd International Symposium on Cerebral Blood Flow and Metabolism) in Amsterdam, Netherlands, 7.-11. Juni 2005

31. A. Spudich, E. Kilic, Ü. Kilic, H. Wunderli-Allenspach, C.L. Bassetti and D.M. Hermann. Inhibition of multiple drug resistance (Mdr) transporter-1 potentiates neuroprotective drug action after focal cerebral ischemia in mice. 4th day of Clinical Research, University of Zurich, Switzerland, 17./18.3.2005

32. E. Kilic, Ü. Kilic, C. Matter, T. Lüscher, C. Bassetti and D.M. Hermann.Aggravation of focal cerebral ischemia by tissue-plasminogen activator is reversed by rosuvastatin - Role of endothelial NO synthase. 77. Kongress der Deutschen Gesellschaft für Neurologie, Düsseldorf, Deutschland, 8.10.2004. Aktuelle Neurologie (2004) 31 (S1), S17

33. Y. Wang, E. Kilic, Ü. Kilic, C. Bassetti, H. Marti and D.M. Hermann . Brain-selective VEGF overexpression induces post-ischemic neuroprotection, but also facilitates hemodynamic steal phenomena. 77. Kongress der Deutschen Gesellschaft für Neurologie, Düsseldorf, Deutschland, 8.10.2004. Aktuelle Neurologie (2004) 31 (S1), S16

34. Y. Wang, E. Kilic, Ü. Kilic, C. Bassetti, H.H. Marti and D.M. Hermann. Reduction of ischemic injury after middle cerebral artery (MCA) thread occlusion in VEGF-overexpressing mice.3rd day of Clinical Research, University of Zurich, Zurich, Switzerland, 27.3.2004. Vortragspreis

35. E. Kilic, Ü. Kilic, J. Soliz, M. Gassmann, C.L. Bassetti and D.M. Hermann. Reduction of ischemic injury after transient focal ischemia in transgenic tg21 mice overexpressing erythropoietin (Epo) in the brain. 172. Tagung der Schweizerischen Neurologischen Gesellschaft, Zürich, Schweiz, 20.-22.11.2003

36. E. Kilic, Ü. Kilic, J. Soliz, M. Gassmann, C.L. Bassetti and D.M. Hermann. Reduction of ischemic injury after transient focal ischemia in transgenic tg21 mice overexpressing erythropoietin (Epo) in the brain.Society for Neuroscience Conference, New Orleans, U.S.A., 9.-13.11.2003. Soc. Neurosci. Abstr. (1998) 29

37. E. Kilic, Ue. Kilic, C.L. Bassetti and D.M. Hermann. I.v. TAT-Bcl-XL is protective after focal brain ischemia in mice. Vortrag am 2. Tag der Klinischen Forschung am UniversitätsSpital Zürich, Schweiz, 10.5.2003

38. D.M. Hermann and E. Kilic. Neuroprotection strategies in acute ischemic stroke: TAT-fusion proteins as innovative treatment options. Vortrag an der Frühjahrstagung der Schweizerischen Neurologischen Gesellschaft in Solothurn, Schweiz, 9.5.2003. Posterpreis für zeitgleich präsentiertes Poster.

39. D.M. Hermann and E. Kilic. Aggravation of ischemic injury following tissue-plasminogen activator (t-PA): Experimental evidences and underlying mechanisms. Vortrag an der Jahrestagung der Zerebrovaskulären Arbeitsgemeinschaft der Schweiz (ZAS) in Zürich, Schweiz, 16.1.2003

40. D.M. Hermann and E. Kilic. Beneficial vs. potentially injurious effects of tissue-plasminogen activator (t-PA) in the ischemic brain. Vortrag an der Jahrestagung der Zerebrovaskulären Arbeitsgemeinschaft der Schweiz (ZAS) in Basel, Schweiz, 17.1.2002

D- Posters

1- Kilic E, Spudich A, Kilic U, et al. ABCC1: a gateway for drugs to the ischemic brain Author(s): Conference Information: 13th Congress of the European-Federation-of-Neurological-Societies, SEP 12-15, 2009 Florence, ITALY Source: EUROPEAN JOURNAL OF NEUROLOGY Volume: 16   Pages: 380-380 Supplement: Suppl. 3   Published: OCT 2009

2- Vig R, Kilic U, Kilic E, et al.Delayed erythropoietin administration promotes neuronal survival and axonal sprouting with an increase in the motor recovery after mild focal cerebral ischemia in

12

mice Conference Information: 13th Congress of the European-Federation-of-Neurological-Societies, SEP 12-15, 2009 Florence, ITALYEUROPEAN JOURNAL OF NEUROLOGY Volume: 16   Pages: 40-40 Supplement: Suppl. 3   Published: OCT 2009

3- Jametti LP, Bacigaluppi M, Pluchino S, Kilic E, Kilic U, Salani G, Brambilla E, Comi G, Martino G, Hermann DM. Post-ıschemıc delayed neural stem/precursor cells (npcs) transplantatıon ımproves functıonal outcome throughout multıple neuro-glıa ınteractıons Conference Information: 9th European Meeting on Glial Cells in Health and Disease, SEP 08-12, 2009 Paris, FRANCE Source: GLIA   Volume: 57   Issue: 13   Pages: S55-S55 Supplement: Suppl. S   Published: OCT 2009

4- Kilic U, Yılmaz B, Cam E, Sarıkaya H, Yulug B, Kilic E. Restorative effects of melatonin after stroke in mice. ENEA (European Neuroendocrine Association). Antalya Turkey. October 17-20, 2008

5- Kilic U, Ayar A, Cam E, Sarıkaya H, Yılmaz B, Kilic E. TLR-4 deficiency protects against cerebral ischemia and axotomy-induced neuroprotection. ENEA (European Neuroendocrine Association). Antalya Turkey. October 17-20, 2008

6- E. Kilic, U. Kilic, ME. Schwab, CL. Bassetti, DM. Hermann. Pre-ischemic, but not post-ischemic Nogo-A deactivation aggravates neuronal injury after middle cerebral artery occlusion in mice. FENS Forum 2008 in Geneva. July 12 - 16, 2008

7- Leemburg S, Gao B, Kilic E, Sarnthein J, Bassetti CL. Sleep, neuronal plasticity and functional recovery after stroke. Swiss Society of Sleep Research, Sleep Medicine and Chronobiology (SSSSC), Solothurn (March 5-6, 2008), Switzerland

8- S. Leemburg1, B. Gao1, E. Kilic1, J. Sarnthein1, C. Bassetti. Sleep, EEG spectra, neuronal plasticity and functional recovery after stroke. Zentrum für Klinische Forschung (ZKF) / Center for Clinical Research (CCR) .7th Day of Clinical Research Zurich, March 27, 2008

9- E. Kilic, U. Kilic, DM. Hermann, CL. Bassetti. Delayed melatonin administration promotes neuronal survival, neurogenesis and motor recovery, and attenuates hyperactivity and anxiety after mild focal cerebral ischemia in mice12. Jahrestagung Zerebrovaskuläre Arbeitsgruppe der Schweiz (ZAS) vom 24. Januar 2008. Aarau. Switzerland

10- Pre-ischemic, but not post-ischemic Nogo-A deactivation aggravates neuronal injury after middle cerebral artery occlusion in miceE. Kilic, U. Kilic, ME. Schwab, CL. Bassetti, DM. Hermann. 12. Jahrestagung Zerebrovaskuläre Arbeitsgruppe der Schweiz (ZAS) vom 24. Januar 2008. Aarau. Switzerland

11- Farinelli, G. Hédou, E. Kilic, Hermann, D. Trono, I. M. Mansuy Involvement of PP1-dependent pathways in neuroprotection: ZNZ Symposium 2007 - Neuroscience Center Zurich, 14 Sep.2007

12- Ü. Kilic, E. Kilic, C. L. Bassetti, D. M. Hermann TLR-4 deficiency protects against focal cerebral ischemia and delayed neuronal degeneration: ZNZ Symposium 2007 - Neuroscience Center Zurich, 14 Sep.2007

13- E. Kilic, Ü. Kilic, M. Bacigaluppi, Z. Guo, N. Bin Abdallah, D. P. Wolfer, C. L. Bassetti, D. M. Hermann Delayed melatonin promotes neuronal survival, neurogenesis and motor recovery, and attenuates hyperactivity and anxiety after mild focal cerebral ischemia in mice: ZNZ Symposium 2007 - Neuroscience Center Zurich, 14 Sep.2007

14- A. Spudich, E. Kilic, K. M. Rentsch, H. Wunderli-Allenspach, J.-M. Fritschy, C. L. Bassetti, D. M. Hermann ABCC1: A gateway for drugs to the ischemic brain: ZNZ Symposium 2007 - Neuroscience Center Zurich, 14 Sep.2007

13

15- Kilic E, Kilic U, Hermann DM, Bassetti CL. Restorative effects of melatonin in experimental stroke model. 59th American Academy of Neurology (AAN) Meeting April 28-May-5, 2007 Boston, MA.

16- A. Spudich, E. Kilic, Guo Z, Bacigallupi M, Wunderli-Allenspach, C. L. Bassetti, H. Fritschy, D. M. Hermann Multidrug resistance-associated protein (MRP)-1: Gateway for drugs to the stroke brain. 6th Day of Clinical Research Zurich, March 1-2 2007

17- Kilic Ü, Kilic E, Soliz J, Bassetti CL., Gassmann M.. Transgenic erythropoietin protects from focal cerebral ischemia by a dual pathway involving both erk-1/-2 and akt 6th Day of Clinical Research Zurich, March 1-2 2007

18- B. Gao, E. Kilic, C.R. Baumann, D.M. Hermann, C.L. Bassetti. Gamma-Hydroxybutyrate (GHB) promotes functional recovery and alters expression of neuroplasticity-related genes in a mouse-model of stroke 6th Day of Clinical Research Zurich, March 1-2 2007

19- U. Kilic, Kilic E, Guo Z, C.L. Bassetti, D.M. Hermann. NogoA deficiency aggravates brin injury after transient focal cerebral ischemia. 6th Day of Clinical Research Zurich, March 1-2 2007

20- B. Gao, E. Kilic, C.R. Baumann, D. Hermann, C.L. Bassetti, Gamma-hydroxybutyrate (GHB) promotes functional recovery and alters expression of neuroplasticity-related genes in a mouse-model of stroke. Schweizerische Neurologische Gesellschaft (178. Tagung) 31. 5. - 2. 6. 2007, Palazzo dei Congressi, Lugano

21- U. Kilic, E. Kilic, J. Soliz, C.L. Bassetti, M. Gassmann, D.M. Hermann, Transgenic erythropoietin (Epo) protects from focal cerebral ischemia by a dual pathway involving both ERK-1/-2 and Akt Zürich Schweizerische Neurologische Gesellschaft (178. Tagung) 31. 5. - 2. 6. 2007, Palazzo dei Congressi, Lugano

22- U. Kilic, E. Kilic, A. Spudich, C.L. Bassetti, H.H. Marti, D.M. Hermann, Human Vascular Endothelial Growth Factor Protects Axotomized Retinal Ganglion Cells In Vivo by Activating ERK-1/2 and Akt Pathways Schweizerische Neurologische Gesellschaft (178. Tagung) 31. 5. - 2. 6. 2007, Palazzo dei Congressi, Lugano

23- U. Kilic, E. Kilic, Z. Guo, C.L. Bassetti, M.E. Schwab, D.M. Hermann, NogoA deficiency aggravates brain injury after transient focal cerebral ischemia in mice      Zürich Schweizerische Neurologische Gesellschaft (178. Tagung) 31. 5. - 2. 6. 2007, Palazzo dei Congressi, Lugano

24- Bacigaluppi M, Kilic E, Pluchino S, Deleidi M, Spudich A, Zanotti L, Bassetti Cl, Comi G, Wolfer D, Martino G, Hermann DM. Postacute intravenous delivery of adult neural precursor (stem) cells promotes functional recovery after focal cerebral ischemia in mice. Swiss Society for Neuroscience, NCCR “Neural Plasticity and Repair” Swiss Multiple Sclerosis Society, March 9 - 10, 2007 Berne

25- Heitz F, Hedou G, Kilic E, Hermann DM., Trono D, Mansuy I. Involvement of pp1-dependent pathways in neuroprotection Swiss Society for Neuroscience, NCCR “Neural Plasticity and Repair” Swiss Multiple Sclerosis Society, March 9 - 10, 2007 Berne

26- Gao B, Kilic E, Baumann Ch., Hermann DM, Bassetti CL. Gamma-hydroxybutyrate (ghb) promotes functional recovery and alters expression of neuroplasticity-related genes in a mouse-model of stroke Swiss Society for Neuroscience, NCCR “Neural Plasticity and Repair” Swiss Multiple Sclerosis Society, March 9 - 10, 2007 Berne

27- Spudich A, Kilic E, Guo Z, Bacigaluppi M, Wunderli-Allenspach H, Bassetti CL., Fritschy JM, Hermann DM. Multidrug resistance-associated protein (mrp)-1: a gateway for drugs to the stroke brain Swiss Society for Neuroscience, NCCR “Neural Plasticity and Repair” Swiss Multiple Sclerosis Society, March 9 - 10, 2007 Berne

14

28- Kilic Ü, Kilic E, Guo Z, Bassetti CL., Schwab ME., Hermann DM. Nogoa deficiency aggravates brain injury after transient focal cerebral ischemia Swiss Society for Neuroscience, NCCR “Neural Plasticity and Repair” Swiss Multiple Sclerosis Society, March 9 - 10, 2007 Berne

29- Kilic Ü, Kilic E, Soliz J, Bassetti CL., Gassmann M, Hermann DM. Transgenic erythropoietin protects from focal cerebral ischemia by a dual pathway involving both erk-1/-2 and akt Swiss Society for Neuroscience, NCCR “Neural Plasticity and Repair” Swiss Multiple Sclerosis Society, March 9 - 10, 2007 Berne.

30- E Kilic, DM. Hermann, A Spudich, M Bacigaluppi, U Kilic and CL Bassetti. Systemic administration of melatonin stimulates endogenous neurogenesis and improves neuronal survival after focal cerebral ischemia. Swiss Society for Neuroscience, Swiss Society for Neuroradiology, Jan 28th 2006

31- DM. Hermann, A Spudich, M E Kilic, Kilic UWunderli-Allenspach H, and CL Bassetti. Inhibition of Multidrug resistance-associated protein (mrp)-1: facilitates neuroprotective therapies after focal cerebral ischemia. Swiss Society for Neuroscience, Swiss Society for Neuroradiology, Jan 28th 2006

32- E Kilic, Kilic U, Marti H, CL Bassetti, DM. Hermann. Human VEGF protects RGCs in vivo by activating ERK-1/2 and Akt pathways Swiss Society for Neuroscience, Swiss Society for Neuroradiology, Jan 28th 2006

33- Kilic U, E Kilic, Spudich A,Jarve K, Bieber K, CL Bassetti, Marti H, DM. Hermann. Human VEGF protects RGCs in vivo by activating ERK-1/2 and Akt pathways ZNZ Symposium 20th

Oct 2006

34- A Spudich, E Kilic, Rentsch K, Wunderli-Allenspach H, and CL Bassetti DM. Hermann,. Inhibition of Multidrug resistance-associated protein (mrp)-1: facilitates neuroprotective therapies after focal cerebral ischemia. ZNZ Symposium 20th Oct 2006

35- Kilic E, Kilic U, Wolfer D Bassetti CL, Hermann DM. Restorative effects of melatonin in experimental stroke model. ZNZ Symposium 20th Oct 2006

36- E Kilic, Kilic U, Wang Y, CL Bassetti, Marti H, DM. Hermann. The phosphatidylinositol-3 kinase/ Akt pathway mediates VEGF activity and induces BBB permeability after focal ischemia Neurowoche 2006 Arbeitsgemeinschaft Klinische Neurowissenschaften 20-24.9.2006

37- A Spudich, E Kilic, U Kilic, Rentsch K, Wunderli-Allenspach H, and CL Bassetti DM. Hermann,. Inhibition of Multidrug resistance-associated protein-1: facilitates neuroprotective therapies after focal cerebral ischemia. Neurowoche 2006 Arbeitsgemeinschaft Klinische Neurowissenschaften 20-24.9.2006

38- U Kilic, E Kilic, CL Bassetti, HH Marti, DM Hermann. Human VEGF protects axotomized retinal ganglion cells in vivo by activating ERK-1/-2 and Akt pathways. Society for Neuroscience, 30 th Annual Meeting. Atlanta, Georgia, from October 14-18 , 2006

39- E. Kilic, U. Kilic, C.L. Bassetti, D.M. Hermann Melatonin reverses tissue-plasminogen activator (t-PA)-induced brain injury after focal cerebral ischaemia in mice: role of inducible NO synthase and phosphatidyl inositol-3 kinase/ Akt. 15th Meeting of the European Neurological Society which will take place in Vienna, 18 - 22 June, 2005.

40- E. Kilic, U. Kilic, J. Soliz, C.L. Bassetti, M. Gassmann, D.M. Hermann Erythropoietin protects from focal cerebral ischaemia by a dual pathway involving both ERK-1/-2 and Akt. 15th Meeting of the European Neurological Society which will take place in Vienna, 18 - 22 June, 2005.

41- E. Kilic, Ü. Kilic, C.L. Bassetti and D.M. Hermann Melatonin reverses tissue-plasminogen activator (t-PA)-induced brain injury after intraluminal middle cerebral artery occlusion: Role of inducible NO synthase and phosphatidyl inositol-3 kinase/ Akt. Brain 05, Amsterdam

15

42- E. Kilic. TAT fusion proteins as innovative treatment strategy in stroke. Brain 05 (22nd International Symposium on Cerebral Blood Flow and Metabolism) in Amsterdam, Netherlands, 7.-11. Juni 2005

43- Ü. Kilic1, E. Kilic1, J. Soliz2, C.L. Bassetti1, M. Gassmann2 and D.M. Hermann1 Transgenic erythropoietin protects from focal cerebral ischemia by a dual pathway involving both ERK-1/-2 and Akt Brain 05, Amsterdam

44- HH Marti, Y Wang1, E Kilic1, Ü Kilic1, CL Bassetti1, DM Hermann1 Transgenic VEGF induces post-ischemic neuroprotection, but facilitates hemodynamic steal phenomena Brain 05, Amsterdam

45- A. Spudich1, R. Frigg2, E. Kilic1, Ü. Kilic1, B. Oesch2, A. Raeber2, C.L. Bassetti1 and D.M. Hermann1Aggravation of ischemic brain injury by prion protein deficiency, but lack of neuroprotection by elevated prion protein levels: Role of tyrosine kinases Brain 05, Amsterdam

46- A. Spudich1, E. Kilic1, Ü. Kilic1, H. Wunderli-Allenspach2, C.L. Bassetti1 and D.M. Hermann1

Inhibition of multiple drug resistance (Mdr) transporter-1 potentiates neuroprotective drug action after focal cerebral ischemia in mice 9th EFNS Congress, Athen, Greece, Sep. 17-20 2005

47- E. Kilic, Ü. Kilic, C.L. Bassetti and D.M. Hermann Melatonin reverses tissue-plasminogen activator (t-PA)-induced brain injury after intraluminal middle cerebral artery occlusion: Role of inducible NO synthase and phosphatidyl inositol-3 kinase/ Akt. 9th EFNS Congress, Athen, Greece, Sep. 17-20 2005

48- E. Kilic1, Ü. Kilic1, , J. Soliz2, C.L. Bassetti1, M. Gassmann2 and D.M. Hermann1 Transgenic erythropoietin protects from focal cerebral ischemia by a dual pathway involving both ERK-1/-2 and Akt 9th EFNS Congress, Athen, Greece, Sep. 17-20 2005

49- E. Kilic1, Ü. Kilic1, J. Soliz2, C.L. Bassetti1, M. Gassmann2 and D.M. Hermann1 Transgenic erythropoietin protects from focal cerebral ischemia by a dual pathway involving both ERK-1/-2 and Akt Brain 05, Amsterdam

50- Kilic E,1 Kilic Ü,1 Soliz J,2 Bassetti CL,1 Gassmann M,2 Hermann DM,1 Transgenic erythropoietin (epo) protects from focal cerebral ischemia by dual pathway involving botr ERK-1/2 and Akt.``4th Day Clinical Research Zurich March 10-11, 2005

51- Kilic E,1 Kilic Ü,1 Bassetti CL, Hermann DM,1 Melatonin reverses t-PA induced brain injury after intraluminal MCAo: Role of iNOS and PI-3/Akt.``4th Day Clinical Research Zurich March 10-11, 2005

52- Spudich A, Frigg R, Kilic E,1 Kilic Ü,1 Oesch B, Raeber A, Bassetti CL, Hermann DM,1

Aggravation of ischemic brain injury by prion protein deficiency: Role of tyrosine kinases. 4th

Day Clinical Research Zurich March 10-11, 2005

53- A. Spudich1, E. Kilic1, Ü. Kilic1, H. Wunderli-Allenspach2, C.L. Bassetti1 and D.M. Hermann1

Inhibition of multiple drug resistance (Mdr) transporter-1 potentiates neuroprotective drug action after focal cerebral ischemia in mice 4th Day Clinical Research Zurich March 10-11, 2005

54- Wang Y, Kilic E, Kilic U, CL Bassetti, Marti HH, Hermann DM. Transgenic VEGF induces post-ischemic neuroprotection, but facilitates haemodynamic steal phenomena. 4th Day Clinical Research Zurich March 10-11, 2005

55- Kilic E,1 Kilic Ü, 1 Matter C, 2 Lüscher T, 2 Bassetti CL, 1 Hermann DM,1 Aggravation of focal cerebral ischemia by tissue-plasminogen activator is reversed by rosuvastatin - role of endothelial no synthase,``9th International Symposium on Pharmacology of Cerebral Ischemia, Marburg, Germany, 2004.

56- Wang Y,1, 2 Kilic E,1 Kilic Ü,1 Bassetti CL,1 Marti HH,2 Hermann DM,1 Brain-selective vegf overexpression induces post-ischemic neuroprotection, but also facilitates hemodynamic steal

16

phenomena. ,``9th International Symposium on Pharmacology of Cerebral Ischemia, Marburg, Germany, 2004.

57- Kilic U, Kilic E, Wang Y, Bassetti CL, Marti HH, Hermann DM. The phosphatidylinositol-3 kinase/ Akt pathway mediates VEGF's neuroprotective activity and induces blood brain barrier permeability after focal cerebral ischemia. ZNZ Symposium 2005 21. Oct 2005

58- A. Spudich1, Xsing H, E. Kilic1, Ü. Kilic1, H. Wunderli-Allenspach2, C.L. Bassetti1 and D.M. Hermann1 Inhibition of multiple drug resistance (Mdr) transporter-1 potentiates neuroprotective drug action after focal cerebral ischemia in mice ZNZ Symposium 2005 21. Oct 2005

59- Spudich A, Frigg R, Kilic E,1 Kilic Ü,1 Oesch B, Raeber A, Bassetti CL, Hermann DM,1

Aggravation of ischemic brain injury by prion protein deficiency: Role of Erk-1/2 and STAT-1. ZNZ Symposium 2005 21. Oct 2005

60- E. Kilic1, Ü. Kilic1, , J. Soliz2, C.L. Bassetti1, M. Gassmann2 and D.M. Hermann1 Transgenic erythropoietin protects from focal cerebral ischemia by a dual pathway involving both ERK-1/-2 and Akt. ZNZ Symposium 2005 21. Oct 2005

61- Ü. Kilic, E. Kilic, J. Soliz, M. Gassmann, C. Bassetti, D. Hermann (Zürich, CH) Neuron-selective erythropoietin (Epo) overexpression protects against transient focal ischemia and retinal ganglion cell axotomy in mice via multiple signaling pathways. DGN Kongress 2004 Düsseldorf

62- E. Kilic, Ü. Kilic, C. Matter, T. Lüscher, C. Bassetti, D. Hermann (Zürich, CH) Aggravation of focal cerebral ischemia by tissue-plasminogen activator is reversed by rosuvastatin - Role of endothelial NO synthase. DGN Kongress 2004 Düsseldorf

63- Y. Wang, E. Kilic, Ü. Kilic, C. Bassetti, H. Marti, D. Hermann (Zürich, CH; Heidelberg) Brain-selective VEGF overexpression induces post-ischemic neuroprotection, but also facilitates hemodynamic steal phenomena. DGN Kongress 2004 Düsseldorf

64- Kilic E,1 Kilic Ü,1 Soliz J,2 Gassmann M,2 Bassetti CL,1 Hermann DM, Injury reduction after transient focal ischemia in transgenic mice overexpressing erythropoietin (epo) in the brain. Society for Neuroscience, 2003

65- E. Kilic , U. Kilic, C.L. Bassetti and D.M. Hermann. I.v. TAT-Bcl-XL is protective after focal brain ischemia in mice. Vortrag am 2. Tag der Klinischen Forschung am UniversitätsSpital Zürich, Schweiz, 10.5.2003

66- E. Kilic, Ü. Kilic, , J. Soliz, M. Gassmann, C. Bassetti, D. Hermann (Zürich, CH) Reduction after transient focal ischemia in tg21 mice overexpressing Epo in the brain. ZNZ Symposium 3003, Zürich

67- E. Kilic , U. Kilic, C.L. Bassetti and D.M. Hermann. Neuroprotection strategies in acute ischemic stroke: TAT-fusion proteins as innovative treatment options. Vortrag / Poster an der Frühjahrstagung der Schweizerischen Neurologischen Gesellschaft in Solothurn, Schweiz, 9.5.2003

68- Kilic, E . and M.Bähr,``Combination therapy of rt-PA with nmda antagonist MK-801 after transient focal ischemia,``9th International Symposium on Pharmacology of Cerebral Ischemia, Marburg, Germany, 2002.

69- Kilic, E ., Ü. Kilic, G. Dietz ve M. Bähr, ``Tat-fusion protein mediated neuroprotective protein delivery after transient focal cerebral ischemia,``9th International Symposium on Pharmacology of Cerebral Ischemia, Marburg, Germany, 2002.

70- Kilic, E., G.P.H. Dietz, D. M. Hermann, and M. Bähr. (2001). TAT-Bcl-XL protein reduces infarct size after focal cerebral ischemia in mice . 4 th Meeting of the German Neuroscience Society 28 th Göttingen Neurobiology Conference Göttingen Germany

17

71- Kilic, E., D.M. Hermann, Ü. Kilic, S. Kügler and M. Bähr; (2001). Adenovirally administered Bcl-XL is protective against striatal injury following intraluminar thread occlusion in mice. 4 th Meeting of the German Neuroscience Society 28 th Göttingen Neurobiology Conference Göttingen Germany

72- Dietz, G.P.H. Kilic, E., and Bähr, M. (2001). Inhibition of apoptosis by transduction of TAT- Bcl-XL protein in vitro and in vivo. 4 th Meeting of the German Neuroscience Society 28 th Göttingen Neurobiology Conference Göttingen Germany

73- Dietz, G.P.H. Kilic, E., Hoffmann, E., Bähr, M. and Isenmann S. (2000). Deletion of Bcl-2 does not decrease the number of retinal ganglion cells surviving after optic nerve axotomy. Society for Neuroscience, 30 th Annual Meeting. New Orleans, LA, USA.

74- Kilic, E., Dietz, G.P.H. and Bähr, M. (2000). Effects of TAT- Bcl-XL after focal cerebral ischemia and reperfusion injury in mice. III Neurobiology Conference, Molecular and Cellular Mechanisms of Brain Repair, Torino Italy

75- Dietz, G.P.H. Kilic, E., Hoffmann, E. and Bähr, M. (2000). Inhibition of apoptosis by transduction of TAT- Bcl-XL protein into cerebral granule cells. III Neurobiology Conference, Molecular and Cellular Mechanisms of Brain Repair, Torino Italy.

76- Kilic, E., Bähr, M. and Hermann, D. M. (2000) Dose-dependent effects of recombinant tissue plasminogen activator on ischemic injury after reversible middle cerebral artery occlusion in mice - Role of post-ischemic perfusion. 8. International Symposium on Pharmacology of Cerebral Ischemia, Marburg, Germany.

77- Hermann, D. M Kilic, E., Kügler S., Isenmann, S. and Bähr, M. (2000)Adenovirally administered GDNF and CNTF, but not BDNF are protective against striatal injury following intraluminar thread occlusion in mice. 8. International Symposium on Pharmacology of Cerebral Ischemia, Marburg, Germany.

78- Kilic, E . Hermann, D.M. and Hossmann, K-A. (1999). An experimental model of cerebral thromboembolism and reperfusion in mice. Brain 1999 Symposium, Copenhagen, Denmark. J Cereb Blood Flow Metab. 19: (1-suppl) 593

79- Tiesler, Ch. Kilic, E. Hossmann, K-A. Gillardom, F. (1999). Pro- and Anti- Apoptotic Signaling Pathways are activated after MCAo in Mice. 24 th AHA International Conference on Stroke and Cerebral Circulation, Tennese, USA. Stroke. 30:(suppl) 233.

80- Tiesler, Ch. Kilic, E. Hossmann, K-A. Gillardom, F. (1998). Increase in Bad following transient middle cerebral artery occlusion in mice. 7. International Symposium on Pharmacology of Cerebral Ischemia, Marburg, Germany.

81- Kelestimur, H. Mogolkoc, R. Baltaci, A.K. Dogru, O. Kilic, E. Kutlu, S. Sarsilmaz, M (1997). The effects of thyroidectomy and propylthiouracil-induced hypothyroidism on the vasopressin response to hypovolemic antihypertonic stimuli in the rat. 33. International congress of Physiological Sciences, St. Petersburg, Russian.

82- Kelestimur, H. Baltaci, A.K. Mogolkoc, R. Semercioz, A. Kilic, E. Kutlu, S. (1997). Plasma renin activity and kidney damage in response to acute renal ischemia and ramipril treatment in ovariectomized and uninephrectomized rats. 33. International Congress of Physiological Sciences, St. Petersburg

83- Taskin O, Birincioglu M, Olmez E, Aksoy T, Kilic E, Wheeler JM. (1997). The effects of estrogen/Progesterone replacement therapy with or without low-dose testosterone on ischemia-reperfusion induced ventricular arrhytmias in ovariectomized rats. Fertility and Sterility. S10 (suppl)

Türkish National Congress

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84- Kilic U, Uğur M, Yücel M, Eyüboğlu S, Büyükgüçlü G, Yılmaz B, Kilic E, VEGF tedavisinin

beyin felci sonrası beyin plastisitesi ve fonksiyonel iyileşmeye olan etkileri. 9. Ulusal

Sinirbilimleri Kongresi, 13-17 Nisan 2010, Istanbul

85- Kilic U, Uğur M, Uslu u, Cumbul A, Yılmaz B, Kilic E. Nogo-A proteinin reperfüzyon sonrası

hücre yaşamına olan etkileri. 9. Ulusal Sinirbilimleri Kongresi, 13-17 Nisan 2010, Istanbul

86- Eyüboğlu S, Büyükgüçlü G, Uğur M, Gençol T, Piranen E, Kilic U, Yılmaz B, Kilic E. NMDA

reseptör antagonisti memantinin beyin felci sonrası oluşan beyin hasarına ve rt-PA toksisitesine

olan etkileri. 9. Ulusal Sinirbilimleri Kongresi, 13-17 Nisan 2010, Istanbul

87- Uğur M, Kilic U, Yılmaz B, Büyükgüçlü G, Piranen E, Eyüboğlu S, Kilic E, Melatonin

reseptörlerinden MT1 ve MT2’nin beyin felci tedavisindeki rolleri. 9. Ulusal Sinirbilimleri

Kongresi, 13-17 Nisan 2010, Istanbul

88- E. Kilic , Ü. Kılıç, M. Uğur, B. Yılmaz, D. Hermann Nogo-A İbnhibisyonunun Beyin Hasarı Sonrası Hücre Yaşamına Olan Etki Ve Mekanizmaları. 35. ulusal Fizyoloji Kongresi, Gazi Universitesi, Ankara, 30 Eylül- 3 Ekim 2009

89- Ü. Kılıç, M. Uğur, M. Gassmann, E. Kilic Beyin Felci Sonrası Subakut Eritopoetin Uygulamasının Hücre Yaşamı Aksonal Plastisite Ve Fonksiyonel İyileşmeye Olan Etkileri35. ulusal Fizyoloji Kongresi, Gazi Universitesi, Ankara, 30 Eylül- 3 Ekim 2009

90- E. Kilic Entering new avenues for stroke treatment, Neuroscience Symposium, 09-13 April 2007, Zonguldak, Turkey

91- Yulug, B., Kilic, U., Kilic, E and Bahr M. Rifampisinin serebral iskemideki nöroprotektif etkisi. 39. National Neurology Congress, Antalya, Turkey

92- Kilic, E., G.P.H. Dietz, D. M. Hermann, and M. Bähr. (2001). Transduction of TAT-Bcl-XL

protein reduces infarct size after focal cerebral ischemia in mice. TUBITAK Beyin Arastirmalari Planlama ve Koordinasyon Komisyonu, Türkiye`de Nörobilimlerin Bugünü ve Gelecegi Toplantisi, Bursa

93- Kilic, E. Hermann D.M. (1999). An Experimental Model of Cerebral Thromboembolism and Reperfusion in Mice. 25th Congress of the Turkish Physiological Society, Elazig

94- Kilic, E. Hermann, D.M. and Hossmann, K-A. (1998). Erken Dönemde Uygulanan rekombinant doku plazminojen aktivatörü`nün Fokal serebral iskemi, reperfüzyon hasari ve beyin ödemi üzerine etkisi üzerin. Türk Nöroloji Dergisi. 4: 24

95- Kilic, E . Hermann, D.M. and Hossmann, K-A. (1998). Farelerde Tromboemboli Yoluyla Fokal Serebral Iskemi Modelinin Gelistirilmesi.34. National Neurology Congress, Bursa, Turkey. Türk Nöroloji Dergisi. 4: 18

96- Ozdemir, Y.G. Kilic, E. Bolay, H. Kelestimur, H. Dalkara T. (1998). Eksojen verilen ve endojen salinan melatoninin fokal serebral iskemide nöroprotektif etkisi. 34. National Neurology Congress, Bursa, Turkey. Türk Nöroloji Dergisi. 4: 83

97- Kelestimur, H. Sarsilmaz, M. Ilhan, N. Ustündag, B. Semercioz, A. Baltaci, A.K. Mogolkoc, R. Kilic, E. (1996). Akut böbrek iskemisi olusturulan ovariyektomili ve tek tarafli nefrektomize ratlarda ramipril`in böbrek üzerine etkisi. 13. National Pharmacology Congress, Antalya, Turkey.

98- Kelestimur, H. Semercioz, A. Ustündag, B. Baltaci, A.K. Mogolkoc, R. Kilic, E. Sarsilmaz, M. (1996). Akut böbrek iskemisinin ve ACE inhibitörleri (ramipril) ile tedavinin ovariyektomi

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uygulanan sicanlarda plazma renin aktivitesi üzerine etkileri. 22. National Physiology Congress, Antalya, Turkey.

Book Chapter

1. Cam E, Kilic E, Yulug B, Ritz M: Occlusion of the Middle Cerebral Artery in Rats. Poindron P, Piguet P (eds): New Animal Models of Human Neurological Diseases. BioValley Monogr. Basel, Karger, 2008, vol 2, pp 52-65

2. Mies G., Trapp T, Kilic E, Oláh L, Hata R, Hermann DM, Hossmann K-A Relationship between DNA fragmentation, energy state, and protein synthesis after transient focal cerebral ischemia in mice`` In: Maturation Phenomenon in Cerebral Ischemia IV, Bazan NG ed, Springer-Verlag, Berlin & Heidelberg, 2002.

Workshop

1. Redei E, Kilic E.Neurobehavioral and Psychiatric Disorders Models Workshop. Neuroendocrinology symposium & Workshop, Yeditepe University, 23- 25 April 2009

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