CURRICULUM VITAE Dr. Pradeep Kumar, 1`` !~ 1a CURRICULUM VITAE Dr. Pradeep Kumar, FNASc Name Dr. Pradeep Kumar Address Division of Organic Chemistry National Chemical Laboratory

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    1`` !~ 1a

    CURRICULUM VITAE Dr. Pradeep Kumar, FNASc

    Name Dr. Pradeep Kumar Address Division of Organic Chemistry

    National Chemical Laboratory Pune-411008, India Phone: 0091-20-25902050 Fax: 0091-20-25902629 E- Mail: pk.tripathi@ ncl.res.in http://www.ncl.org.in/pktripathi

    Date of Birth July 20, 1957 Marital Status Married Present Position Scientist G, NCL, Pune Academic background (all in India)

    Degree Year University Division

    B.Sc 1975 Gorakhpur University First

    M.Sc. 1977 Gorakhpur University First

    Ph.D. 1981 Banaras Hindu University Thesis

    Title of thesis

    " Studies in Heterocycles Using Imines and Oximes as Synthons"

    Supervisor : Prof. A. K. Mukerjee

    Research Experience

    Basic and Applied aspects of Synthetic Organic Chemistry Post- Doctoral Experience : 1. June 1988 to March 1990 as DAAD Fellow with Prof. H. J.

    Bestmann at institute of Organic Chemistry, University of Erlangen-Nurnberg, Germany.

    2. May 1996 to October 1997 as Alexander von Humboldt Fellow with Prof. R. R. Schmidt at Faculty of Chemistry, University of Konstanz, Germany.

    3. October 2003 to December 2003 as Alexander von Humboldt fellow with Professor Martin E. Maier at institute of Organic Chemistry, university of Tuebingen, Tuebingen, Germany

    4. September 2006 to November 2006 as Alexander von Humboldt Fellow with Professor J. Rademann at institute for Molecular Pharmacology (FMP), Berlin-Buch, Berlin, Germany

    5. March 2010 to May 2010 as Alexander von Humboldt Fellow with Professor J. Rademann at institute for Molecular Pharmacology (FMP), Berlin-Buch, Berlin, Germany

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    Research Interest Positions held

    Development of synthetic methodologies, Asymmetric synthesis, total synthesis of biologically active compounds, zeolites and solid acids induced organic transformations During my Ph. D programme at Banaras Hindu University, I was awarded fellowship from UGC and CSIR from 1977 to 1981. Recipient of DAAD Fellowship from June 1988 to March 1990 and Alexander von Humboldt Fellowship from May 1996 to October 1997, October to December 2003, September to November 2006, March to May 2010

    Professional Career Highlights Honours & Awards

    Lecturer at postgraduate college Barhalganj, Gorakhpur affiliated with Gorakhpur University, Nov. 1981 May 1982. Scientist B, 1983 1988 at NCL, Pune, Scientist C, 1988 1993 at NCL, Pune Scientist EI, 1993 1998 at NCL, Pune Scientist E-II, 1998- 2003 at NCL, Pune Scientist F, 2003- 2008 at NCL, Pune Scientist G, 2008 onwards at NCL, Pune Excellent training in organic chemistry as evidenced by solid publications (156 Nos.), Managerial instincts demonstrated by successfully running the research group (15 Ph.D. produced) at present comprising of 13 Ph. D. research scholars and also by serving as a member of divisional administrative council (DAC) of NCL. Delivered invited lectures in universities and institutions both in India and Abroad. Initiated several projects in basic research on methodology development and asymmetric synthesis of complex natural products. Over 25 years research experience and leadership in both applied and basic aspects of chemistry. Worked in the capacity as project leader on several projects sponsored by pharmaceutical industries and government funding agencies including NMITLI, a mega project of the Govt. of India (CSIR). 2009, Eli- Lilly Asia outstanding Ph.D. thesis award 2009 ( First Prize) to my student, Dr. Satyendra Kumar Pandey, Eli- Lilly Asia outstanding Ph.D. thesis award, 2010 (Second Prize) to my student, Dr. Nagendra Kondekar Member of the executive council of Maharashtra Academy of Sci. (2001-2003), DAC Member of Organic division of NCL (2010-contd) Fellow of Maharashtra Academy of Sciences 1999, ICICI Technology of the Year Award 1999 of the NCL research Foundation Indo-Taiwan delegation member (DST, New Delhi- National Science Council, Taiwan)2007, Prof. A.S.R. Anjaneyulu 60th Birthday Commemoration award- 2011, Scientist of the year award- 2012 of NCL Research Foundation Fellow of National Academy of Sciences (FNASc) (2007) CRSI- Bronze medal award (2009-10),OPPI Scientist award- 2012

    List of Publications Total No. of Publications 157, Patents 13 (including US patents 5)

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    Publications of Dr. Pradeep Kumar

    Total number of papers: 157 h-index: 28

    Account:

    1. Pradeep Kumar*, Rajiv Kumar and Bipin Pandey

    Oxidative organic transformations catalyzed by titanium- and vanadium silicate molecular sieves

    Synlett 1995, 289.

    2. 3.

    Pradeep Kumar*, Priti Gupta Pradeep Kumar*, Namrata Dwivedi

    Hydrolytic kinetic resolution as an emerging tool in the synthesis of bioactive molecules Proline catalyzed -aminoxylation reaction in the synthesis of biologically active compounds

    Synlett 2009, 1367 Accounts of Chemical Research 2013, 46, 289-99

    Review articles:

    4. Arya K. Mukerjee and Pradeep Kumar

    The chemistry of 4,5-dihydro-5-oxo-1,3-oxazoles

    Heterocycles 1981, 16, 1995.

    5.

    Pradeep Kumar, Rajiv Kumar and Bipin Pandey

    Oxidative organic transformations catalyzed by titanium silicate molecular sieves

    J. Ind. Inst. of Science, 1994, 293.

    6. Pradeep Kumar* Vasudeva Naidu and Priti Gupta

    Application of hydrolytic kinetic resolution (HKR) in the synthesis of bioactive compounds

    Tetrahedron 2007, 63, 2745

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    Research Papers:

    7. Pradeep Kumar, * A desymmetrization approach to the Advanced Synthesis

    Partha Sarathi Chowdhury enantiopure syn/anti-1,5-diols via & Catalysis 2013

    Menaka Pandey hydrolytic kinetic resolution (HKR) of

    functionalized meso bis-epoxides:

    Further elaboration to syn/syn-1,3,5- triols

    and application to the formal synthesis of

    cryptocarya diacetate

    8. A.Harbindu,B.Sharma Asymmetric routes topentadec-1-en-4-ol: Tetrahedron Asymm. Pradeep Kumar* application to the synthesis of aculeatins F 2013, 24, 305 &epiF, (R)-and(S)-5-hexadecanolide and a formal Synthesis of solenopsin

    9.S. Ramalingam, A.D. Bhise A concise synthesis of ( 5R,6S)-tert-butyl Arkivoc 2013 (ii) K. Show, P. Kumar * 5- acetoxy-6-(hydroxymethyl)-5,6- 220 Dihydropyridine -1(2H)-carboxylate (Invited article) 10 . U. Nookaraju, A. First total synthesis of seimatopolide B RSC advances Harbindu, A.D. Bhise, 2012, 2, 11231 B.M. Sharma, P. Kumar* 11. Pradeep Kumar,* Enantio- and Diastereocontrolled Organic& Biomol.Chem. A. Dubey, A. Harbindu conversion of chiral epoxides 2012, 10, 6987 to trans-cyclopropane carboxylates application to the synthesis of cascarillic acid, grenadamide and L-(-)-CCG-II 12. D. Tripathi, Pradeep Formal synthesis of Tetrahydrolipstatin Tetrahedron Asymm. Kumar * and Tetrahydroesterastatin 2012, 23, 884 13. Pradeep Kumar, * Organocatalytic stereoselective Organic& Biomol.Chem. M. Pandey,P. Gupta, synthesis of passifloricin A 2012, 10, 1820 D.D. Dhavale 14. N. Dwivedi, D. Tripathi An organocatalytic route to the Tet. Asymm. 2011,22 Pradeep Kumar* synthesis of 6S-5,6-dihydro-6[(2R) 1749. -2-hydroxy-6-phenylhexyl]-2H-pyran-2-one

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    15. Anand Harbindu, Organocatalytic enantioselective Synthesis 2011,1954 Pradeep Kumar* approach to the synthesis of (Invited article) Verbalactone and (R)-Massoialactone 16. Krishanu Show, Priti Stereoselecive synthesis of ophiocerin Tetrahedron Gupta, Pradeep Kumar* A and C Asymmetry 2011, 22, 1212 17. Krishanu Show, P.K. An asymmetric dihydroxylation route Tet. Asymm. Upadhyay, Pradeep to (-)-bulgecinine 2011, 22, 1234 Kumar* 18. Nagendra B. Kondekar Synthesis of (R)- selegiline Synth. Comm 2011, Pradeep Kumar* via hydrolytic kinetic resolution 41, 1301 19. Abhisek Dubey, Stereoselective synthesis of (-)- Synthesis 2011, 901 A.K. Harbindu, galantinic acid Pradeep Kumar* 20.

    Pradeep Kumar*, Menka Pandey, Priti Gupta, and Dilip Dhavale

    An organocatalytic route to the synthesis of lactone moiety of compactin and mevinolin

    Tetrahedron Lett. 2010, 51, 5838

    21. 22..

    Pradeep Kumar*, Abhishek Dubey, Vedavati G. Puranik Pradeep Kumar*, Menka Pandey, Priti Gupta, Vasudeva Naidu and Dilip Dhavale

    A general and concise asymmetric synthesis of sphingosine, safingol and phytosphingosine via tethered aminohydroxylation Enantio- and diastereocontrolled total synthesis of (+)- strictifolione

    Org. Bio.Chem. 2010, 8, 5074 Eur. J. Org.Chem. 2010, 6993

    23.

    Puspesh K. Upadhyay and Pradeep Kumar*

    A Short and Efficient Synthesis of (S)-(+)-2-(Hydroxymethyl)-6- piperidin-2-one

    Synthesis 2010, 2512

    24.

    Puspesh K. Upadhyay and Pradeep Kumar*

    A Concise Synthesis of(2S,3S,4S)- 2-(Hydroxymethyl)pyrrolidine- 3,4-diol(LAB1)

    Synthesis 2010, 3063

    25.

    Nagendra B. Kondekar, and Pradeep Kumar*

    Synthesis of (R)-Coniine and (S) -Coinicine via Organocatalytic -Aminoxylation of an Aldehyde

    Synthesis 2010, 3105

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    26.

    Vishwajeet Jha, Nagendra B. Kondekar, and Pradeep Kumar*

    Enantioselective Synthesis of syn/anti-1,3-Amino Alcohols via Proline-Catalyzed Sequential Aminoxylation/ - Amination and Horner-Wadsworth-Emmons Olefination of Aldehydes

    Organic Letters, 2010, 12, 2762

    27.

    A. Dubey, Shruti V. Kaulorkar and Pradeep Kumar*

    Synthesis of (-)- galantinic acid via iterative HKR and tethered aminohydroxylation

    Tetrahedron 2010, 66, 3159

    28.

    A. Harbindu, P. Kumar*

    Synthesis of aculeatins A and B via Iterative HKR

    Synthesis 2010, 1479

    29.

    Hassan Hazarkhani, P. Kumar, K.S. Kondiram, I. Gadwal

    Highly selective Claisen Schmidt condensation catalyzed by silica chloride under solvent- free reaction Conditions

    Synth. Commun. 2010, 40, 2887

    30.

    Abhisek Dubey, A.K. Upadhyay and Pradeep Kumar *

    Pivaloyl chloride/DMF: a new reagent for conversion of alcohols to chlorides

    Tetrahedron Lett. 2010, 51, 744

    31.

    Partha S. Chowdhary, P. Gupta and Pradeep Kumar *

    Enantioselective synthesis of Decarestrictine J

    Tetrahedron Lett. 2009, 50, 7188

    32.

    Partha S. Chowdhary, P. Gupta and Pradeep Kumar *

    First asymmetric total synthesis of aspinolide

    Tetrahedron Lett. 2009, 50, 7018

    33. Nagendra B.Kondekar, Iterative approach to enantiopure syn/anti Organic and Pradeep Kumar* 1,3-polyols via proline catalysed sequential Letters -aminoxylation and HWE olefination of 2009, 11, aldehydes 2611 34. Divya Tripathi,

    Satyendra Kumar Pandey and Pradeep Kumar*

    A general approach to medium-sized ring ethers via hydrolytic and oxidative kinetic resolutions: Stereoselective syntheses of (-)-cis-lauthisan and (+)-isolaurepan

    Tetrahedron 2009, 65, 2226

    35. S. Ramalingam and Pradeep Kumar*

    Yttria-zirconia based Lewis acid catalysis of the Biginelli reaction: An efficient one-pot synthesis of 3, 4-dihydropyrimidine-2-(1H)-ones

    Synth. Commun. 2009, 39 (7), 1299

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    36. Abhishek Dubey and Pradeep Kumar*

    Tethered amino hydroxylation route to phytosphingosine

    Tetrahedron Lett. 2009, 50, 3425

    37. Suman Sahoo, Pradeep Kumar, F. Lefebvre, S. B. Halligudi*

    Synthesis of chiral sulfoxides by enantioselective sulfide oxidation and subsequent oxidative kinetic resolution using immobilized Ti-binol complex

    Journal of catalysis 2009, 262, 111.

    38. Puspesh K. Upadhyay, Rajendra Prasad, Menaka Pandey, Pradeep Kumar*

    A facile synthesis of 5,6-dihydro-5-hydroxy-2(1H)-pyridone

    Tetrahedron Lett. 2009, 50, 2440

    39. Suman Sahoo, Pradeep Kumar, F. Lefebvre, S. B. Halligudi*

    Oxidative kinetic resolution of alcohols using chiral Mn-salen complex immobilized onto ionic liquid modified mesoporous silica

    Applied Catalysis A: General 2009, 354, 17

    40. Puspesh K. Upadhyay and Pradeep kumar*

    A novel synthesis of coumarins employing triphenyl(-carboxymethylene)triphenylphosphorane imidazolide as C-2 synthon

    Tetrahedron Lett. 2009, 50, 236

    41. Suman Sahoo, Pradeep Kumar, F. Lefebvre, S. B. Halligudi*

    A chiral Mn (III) salen complex immobilized onto ionic liquid modified mesoporous silica for oxidative kinetic resolution of secondary alcohols

    Tetrahedron Lett. 2008,49, 4865

    42. Divya Tripathi and Pradeep Kumar*

    A total synthesis of (+)-isolaurepan

    Tetrahedron Lett. 2008,49, 7012

    43. S. Ramalingam and Pradeep Kumar*

    Synthesis of -amino phosphonates by three component condensation of carbonyl compounds, amine and dialkyl phosphates using Yttria-Zirconia based Lewis acid catalyst

    Catalysis Letters 2008, 125, 315.

    44. S. Ramalingam and Pradeep Kumar*

    Multi-component carbon-carbon bond forming Mannich reaction catalyzed by Yttria-Zirconia based Lewis acid

    Catalysis communications 2008, 9, 2445

    45. Suman Sahoo, Pradeep Kumar, F. Lefebvre, S...

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