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DDICC Overview: biomedical and healthCAre Data Discovery Index Ecosystem Lucila Ohno-Machado, MD, PhD UCSD Biomedical Informatics NIH BD2K Joint Kick-off Meeting Rockville, MD, Nov 3-4, 2014

DDICC Overview: biomedical and healthCAre Data Discovery Index Ecosystem Lucila Ohno-Machado, MD, PhD UCSD Biomedical Informatics NIH BD2K Joint Kick-off

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Page 1: DDICC Overview: biomedical and healthCAre Data Discovery Index Ecosystem Lucila Ohno-Machado, MD, PhD UCSD Biomedical Informatics NIH BD2K Joint Kick-off

DDICC Overview:

biomedical and healthCAre Data Discovery Index Ecosystem

Lucila Ohno-Machado, MD, PhD

UCSD Biomedical InformaticsNIH BD2K Joint Kick-off Meeting

Rockville, MD, Nov 3-4, 2014

Page 2: DDICC Overview: biomedical and healthCAre Data Discovery Index Ecosystem Lucila Ohno-Machado, MD, PhD UCSD Biomedical Informatics NIH BD2K Joint Kick-off

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Aims Task Forces

Pilot Project$

• Call for Collaborators to Work on Pilot Projects• Yearly RFA for New Pilots

Administrative Supplements Organization

Page 3: DDICC Overview: biomedical and healthCAre Data Discovery Index Ecosystem Lucila Ohno-Machado, MD, PhD UCSD Biomedical Informatics NIH BD2K Joint Kick-off

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Aims

1. Help users find accessible data By disease, data modality, demographics, etc.

2. Assist data producers on how to publish data for maximal discoverability

Assess of impact of disseminated data

3. Train data producers and data users Tools related to biomedical data sharing

PubMed of Data = DataMed

Page 4: DDICC Overview: biomedical and healthCAre Data Discovery Index Ecosystem Lucila Ohno-Machado, MD, PhD UCSD Biomedical Informatics NIH BD2K Joint Kick-off

Steering CommitteeChair: Ohno-Machado

NIH: Ian Fore, Jennie Larkin, Ron MargolisDawei Lin, Alison Yao (program officers)

Task Force and Community Engagement leaders

Taskforce 1: Data Shop UT Houston: Xu

Pilot Projects

Ontologies and Standards

Taskforce 2: Data Showcase

U Michigan: Alter

Pilot Projects

Visualization and User Needs

Taskforce 3: Data Market

Oxford U: Sansone

Pilot Projects

Incentives and Publishing

Supplements

Collaborating PIs

NIH-funded projects

Data and Expert Knowledge

Management

UCSD: Mahera (general)Farcas (technical)

Community Engagement

UCSD: Martone

Page 5: DDICC Overview: biomedical and healthCAre Data Discovery Index Ecosystem Lucila Ohno-Machado, MD, PhD UCSD Biomedical Informatics NIH BD2K Joint Kick-off

Data Shop

Linking Data to the Literature

Ontology-Based

Discovery Tools

Data Showca

se

Meeting User Needs

Intelligent Search and Visualizatio

n

Data Market

Publishing for Reuse

Citation Networks

and Incentives

1 2 3

Task Forces

Page 6: DDICC Overview: biomedical and healthCAre Data Discovery Index Ecosystem Lucila Ohno-Machado, MD, PhD UCSD Biomedical Informatics NIH BD2K Joint Kick-off

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Administrative SupplementsCOHEN, TREVOR

UNIVERSITY OF TEXAS HOUSTON

Using Biomedical Knowledge to Identify Plausible Signals for Pharmacovigillance

KLEINSTEIN, STEVEN H. YALE UNIVERSITY

Computational Tools for the Analysis of High-throughput Immunoglobulin Sequencing

WAGER,TOR D.

UNIVERSITY OF COLORADO fMRI-based Biomarkers for Multiple Components of Pain

WINSLOW, RAIMOND L

JOHNS HOPKINS UNIVERSITY The Cardiovascular Research Grid

LIU, HONGFANG MAYO CLINIC NLP for Clinical and Translational Research

MATTINGLY, CAROLYN J

NORTH CAROLINA STATE UNIVERSITY

Generation of a Centralized and Integrated Resource for Exposure Data

O'MALLEY, BERT W

BAYLOR COLLEGE OF MEDICINE A Hub for the Nuclear Receptor Signaling Atlas

HRIPCSAK, GEORGE M.

COLUMBIA UNIVERSITY Discovering and Applying Knowledge in Clinical Databases

Page 7: DDICC Overview: biomedical and healthCAre Data Discovery Index Ecosystem Lucila Ohno-Machado, MD, PhD UCSD Biomedical Informatics NIH BD2K Joint Kick-off

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Data Shop Pilots Year 1

Linking Publications and Underlying Data Using NLPHua Xu, UT Houston

Rating Relationship in Imaging Reports: Machine vs. Crowdsourcing ApproachesRicky Taira, UCLA

Page 8: DDICC Overview: biomedical and healthCAre Data Discovery Index Ecosystem Lucila Ohno-Machado, MD, PhD UCSD Biomedical Informatics NIH BD2K Joint Kick-off

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Data Showcase Pilots Year 1

Recommendation System: Machine Learning and CrowdsourcingXiaoqian Jiang, UCSD

Intelligent Search and Visualization of DataTodd Johnson, UT Houston

Page 9: DDICC Overview: biomedical and healthCAre Data Discovery Index Ecosystem Lucila Ohno-Machado, MD, PhD UCSD Biomedical Informatics NIH BD2K Joint Kick-off

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Data Market Pilot Year 1

Citation and Data Access Metrics for a Molecular Data Bank and Related ResourcesPeter Rose, UCSDChun-nan Hsu, UCSD

Page 10: DDICC Overview: biomedical and healthCAre Data Discovery Index Ecosystem Lucila Ohno-Machado, MD, PhD UCSD Biomedical Informatics NIH BD2K Joint Kick-off

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Timeline

Page 11: DDICC Overview: biomedical and healthCAre Data Discovery Index Ecosystem Lucila Ohno-Machado, MD, PhD UCSD Biomedical Informatics NIH BD2K Joint Kick-off

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Thank you!

Questions?