1
tive intervention. Urol Clin North Am, 25: 331, 1998 3. Hoenig, D. M., Shalhav, A. L., Elbahnasy, A. M., McDougall, E. M., Smith, D. and Clayman, R. V.: Impact of etiology of secondary ureteropelvic junction obstruction on outcome of endopyelotomy. J Endourol, 12: 131, 1998 4. Davis, D. M.: Intubated ureterotomy: a new operation for ureteral and ureteropelvic stricture. Surg Gynecol Obstet, 76: 513, 1943 5. Goldfischer, E. R., Jabbour, M. E., Stravodimos, K. G., Klima, W. J. and Smith, A. D.: Techniques of endopyelotomy. Br J Urol, 82: 1, 1998 6. Bernardo, N. O. and Smith, A. D.: Percutaneous endopyelotomy. Urology, 56: 322, 2000 7. Shalhav, A. L., Giusti, G., Elbahnasy, A. M., Hoenig, D. M., McDougall, E. M., Smith, D. S. et al: Adult endopyelotomy: impact of etiology and antegrade versus retrograde approach on outcome. J Urol, 160: 685, 1998 8. Goldfischer, E. R. and Smith, A. D.: Endopyelotomy revisited. Urology, 51: 855, 1998 9. Motola, J. A., Fried, R., Badlani, G. H. and Smith, A. D.: Failed endopyelotomy: implications for future surgery on the uretero- pelvic junction. J Urol, 150: 821, 1993 10. Sigwart, U., Puel, J., Mirkovitch, B., Joffre, F. and Kappenberger, L.: Intravascular stents to prevent occlusion and restenosis after transluminal angioplasty. N Engl J Med, 316: 701, 1987 11. Coons, H. G.: Self-expanding stainless steel biliary stents. Radiology, 170: 979, 1989 12. Kirby, R. S., Heard, S. R., Miller, P., Eardley, I., Holmes, S., Vale, J. et al: Use of the ASI titanium stent in the manage- ment of bladder outflow obstruction due to benign prostatic hyperplasia. J Urol, 148: 1195, 1992 13. Barbalias, G. A., Siablis, D., Liatsikos, E. N., Karnabatidis, D., Yarmenitis, S., Bouropoulos, K. et al: Metal stents: a new treat- ment of malignant ureteral obstruction. J Urol, 158: 54, 1997 14. Barbalias, G. A., Liatsikos, E. N., Kalogeropoulou, C., Karnabatidis, D. and Siablis, D.: Metallic stents in gynecologic cancer: an approach to treat extrinsic ureteral obstruction. Eur Urol, 38: 35, 2000 15. Barbalias, G. A., Liatsikos, E. N., Karnabatidis, D., Yarmenitis, S. and Siablis, D.: Ureteroileal anastomotic strictures: an innova- tive approach with metallic stents. J Urol, 160: 1270, 1998 16. Kagadis, G. C., Patrinou, V., Kalogeropoulou, C. P., Karnabatidis, D., Petsas, T., Nikiforidis, G. C. et al: Virtual endoscopy in the diagnosis of an adult double tracheal bronchi case. Eur J Radiol, 40: 50, 2001 17. Robb, R. A.: Virtual endoscopy: development and evaluation using the Visible Human datasets. Comput Med Imaging Graph, 24: 133, 2000 18. Janetschek, G., Peschel, R., Frauscher, F. and Franscher, F.: Laparoscopic pyeloplasty. Urol Clin North Am, 27: 695, 2000 19. Lo ´pez-Martı ´nez, R. A., Singireddy, S. and Lang, E. K.: The use of metallic stents to bypass ureteral strictures secondary to met- astatic prostate cancer: experience with 8 patients. J Urol, 158: 50, 1997 20. Pauer, W. and Eckerstorfer, G. M.: Use of self-expanding perma- nent endoluminal stents for benign ureteral strictures: mid- term results. J Urol, 162: 319, 1999 21. Antimisiaris, S. G., Siablis, D., Liatsikos, E., Kalogeropoulou, C., Tsota, I., Tsotas, V. et al: Liposome-coated metal stents: an in vitro evaluation of controlled-release modality in the ureter. J Endourol, 14: 743, 2000 EDITORIAL COMMENTS These authors report the use of metal stent for benign ureteropel- vic junction obstruction as an alternative to standard pyeloplasty and a plethora of minimally invasive procedures, such as percutane- ous and ureteroscopic endopyelotomy, Acucise and laparoscopic re- pair. This small experience does not provide a clear advantage over these techniques. There is a need for improved stenting on a long- term basis in long ureteral strictures of the upper ureter, malignant strictures and ureterointestinal strictures. Unlike the successful use of UroLume (American Medical Systems, Minnetonka, Minnesota) for bladder outflow obstruction, in which ex- posure to urine only occurs during voiding, a wide lumen precludes obstruction secondary to hyperplastic tissue response. The use of metal stents in the ureter on a long-term basis has been plagued with these problems. It would be interesting to see if a Wallstent in the upper ureter would be better than in the lower ureter and/or different from other stent designs at longer term followup. Virtual endoscopy provides excellent images of the stent and lu- men. However, it is unable to provide key information, such as epithelialization and function across the stent. Gopal Badlani Department of Urology Long Island Jewish Medical Center New Hyde Park, New York This innovative article describes the first use of a permanent metal stent to treat recurrent ureteropelvic junction obstruction after failed open dismembered pyeloplasty in 4 patients. The followup assessments combine standard imaging with 3-D CT reconstructions of the region of interest, further enhanced by virtual endoscopy with “fly through” sequences within the stent. This new technique joins the ever expanding list of alternative treatments available for ureteropelvic junction obstruction. This fact in itself perhaps reflects our failure to understand the pathophysi- ology of the original condition and more importantly why the so called gold standard treatment of open dismembered pyeloplasty fails. Use of the Wallstent throughout the genitourinary tract has met with mixed success, and the problems with encrustation and exuberant urothelial ingrowth within the interstices and the ends of the stent have limited its uptake. Of the 4 stents reported 3 remain patent but 1 failed at 2 months. One wonders whether this technique is effectively a temporizing method and not a permanent solution for the patients. 3-D CT reconstruction and virtual endoscopy hold great promise. The images in the article are remarkable and are of a quality that we could only dream about until recently. The speed of advances in CT data acquisition and manipulation is extraordinary and it is likely that these types of images will be available from most machines in the near future. The exact role of this technology in the urological imaging armamentarium will need to be discussed at length, partic- ularly with the concerns about the amount of radiation exposure required. Presently 3-D reconstructive techniques are used exten- sively for preoperative planning of open and laparoscopic renal pa- renchymal surgery. Virtual endoscopy is likely to be just as valuable as a preoperative planning tool for renoscopy and perhaps will form the basis of the surgical simulators of the near future. Ken Anson and Roger Kirby Department of Urology St George’s Hospital London, United Kingdom URETEROPELVIC JUNCTION OBSTRUCTION AND METALLIC STENTS 2386

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tive intervention. Urol Clin North Am, 25: 331, 19983. Hoenig, D. M., Shalhav, A. L., Elbahnasy, A. M., McDougall,

E. M., Smith, D. and Clayman, R. V.: Impact of etiology ofsecondary ureteropelvic junction obstruction on outcome ofendopyelotomy. J Endourol, 12: 131, 1998

4. Davis, D. M.: Intubated ureterotomy: a new operation for ureteraland ureteropelvic stricture. Surg Gynecol Obstet, 76: 513, 1943

5. Goldfischer, E. R., Jabbour, M. E., Stravodimos, K. G., Klima,W. J. and Smith, A. D.: Techniques of endopyelotomy. Br JUrol, 82: 1, 1998

6. Bernardo, N. O. and Smith, A. D.: Percutaneous endopyelotomy.Urology, 56: 322, 2000

7. Shalhav, A. L., Giusti, G., Elbahnasy, A. M., Hoenig, D. M.,McDougall, E. M., Smith, D. S. et al: Adult endopyelotomy:impact of etiology and antegrade versus retrograde approachon outcome. J Urol, 160: 685, 1998

8. Goldfischer, E. R. and Smith, A. D.: Endopyelotomy revisited.Urology, 51: 855, 1998

9. Motola, J. A., Fried, R., Badlani, G. H. and Smith, A. D.: Failedendopyelotomy: implications for future surgery on the uretero-pelvic junction. J Urol, 150: 821, 1993

10. Sigwart, U., Puel, J., Mirkovitch, B., Joffre, F. andKappenberger, L.: Intravascular stents to prevent occlusionand restenosis after transluminal angioplasty. N Engl J Med,316: 701, 1987

11. Coons, H. G.: Self-expanding stainless steel biliary stents.Radiology, 170: 979, 1989

12. Kirby, R. S., Heard, S. R., Miller, P., Eardley, I., Holmes, S.,Vale, J. et al: Use of the ASI titanium stent in the manage-ment of bladder outflow obstruction due to benign prostatichyperplasia. J Urol, 148: 1195, 1992

13. Barbalias, G. A., Siablis, D., Liatsikos, E. N., Karnabatidis, D.,Yarmenitis, S., Bouropoulos, K. et al: Metal stents: a new treat-ment of malignant ureteral obstruction. J Urol, 158: 54, 1997

14. Barbalias, G. A., Liatsikos, E. N., Kalogeropoulou, C.,Karnabatidis, D. and Siablis, D.: Metallic stents in gynecologiccancer: an approach to treat extrinsic ureteral obstruction.Eur Urol, 38: 35, 2000

15. Barbalias, G. A., Liatsikos, E. N., Karnabatidis, D., Yarmenitis, S.and Siablis, D.: Ureteroileal anastomotic strictures: an innova-tive approach with metallic stents. J Urol, 160: 1270, 1998

16. Kagadis, G. C., Patrinou, V., Kalogeropoulou, C. P.,Karnabatidis, D., Petsas, T., Nikiforidis, G. C. et al: Virtualendoscopy in the diagnosis of an adult double tracheal bronchicase. Eur J Radiol, 40: 50, 2001

17. Robb, R. A.: Virtual endoscopy: development and evaluationusing the Visible Human datasets. Comput Med ImagingGraph, 24: 133, 2000

18. Janetschek, G., Peschel, R., Frauscher, F. and Franscher, F.:Laparoscopic pyeloplasty. Urol Clin North Am, 27: 695, 2000

19. Lopez-Martınez, R. A., Singireddy, S. and Lang, E. K.: The use ofmetallic stents to bypass ureteral strictures secondary to met-astatic prostate cancer: experience with 8 patients. J Urol,158: 50, 1997

20. Pauer, W. and Eckerstorfer, G. M.: Use of self-expanding perma-nent endoluminal stents for benign ureteral strictures: mid-term results. J Urol, 162: 319, 1999

21. Antimisiaris, S. G., Siablis, D., Liatsikos, E., Kalogeropoulou, C.,Tsota, I., Tsotas, V. et al: Liposome-coated metal stents: an invitro evaluation of controlled-release modality in the ureter.J Endourol, 14: 743, 2000

EDITORIAL COMMENTS

These authors report the use of metal stent for benign ureteropel-vic junction obstruction as an alternative to standard pyeloplastyand a plethora of minimally invasive procedures, such as percutane-ous and ureteroscopic endopyelotomy, Acucise and laparoscopic re-pair. This small experience does not provide a clear advantage overthese techniques. There is a need for improved stenting on a long-term basis in long ureteral strictures of the upper ureter, malignantstrictures and ureterointestinal strictures.

Unlike the successful use of UroLume (American Medical Systems,Minnetonka, Minnesota) for bladder outflow obstruction, in which ex-posure to urine only occurs during voiding, a wide lumen precludesobstruction secondary to hyperplastic tissue response. The use of metalstents in the ureter on a long-term basis has been plagued with theseproblems. It would be interesting to see if a Wallstent in the upperureter would be better than in the lower ureter and/or different fromother stent designs at longer term followup.

Virtual endoscopy provides excellent images of the stent and lu-men. However, it is unable to provide key information, such asepithelialization and function across the stent.

Gopal BadlaniDepartment of UrologyLong Island Jewish Medical CenterNew Hyde Park, New York

This innovative article describes the first use of a permanent metalstent to treat recurrent ureteropelvic junction obstruction afterfailed open dismembered pyeloplasty in 4 patients. The followupassessments combine standard imaging with 3-D CT reconstructionsof the region of interest, further enhanced by virtual endoscopy with“fly through” sequences within the stent.

This new technique joins the ever expanding list of alternativetreatments available for ureteropelvic junction obstruction. This factin itself perhaps reflects our failure to understand the pathophysi-ology of the original condition and more importantly why the socalled gold standard treatment of open dismembered pyeloplastyfails. Use of the Wallstent throughout the genitourinary tract hasmet with mixed success, and the problems with encrustation andexuberant urothelial ingrowth within the interstices and the ends ofthe stent have limited its uptake. Of the 4 stents reported 3 remainpatent but 1 failed at 2 months. One wonders whether this techniqueis effectively a temporizing method and not a permanent solution forthe patients.

3-D CT reconstruction and virtual endoscopy hold great promise.The images in the article are remarkable and are of a quality that wecould only dream about until recently. The speed of advances in CTdata acquisition and manipulation is extraordinary and it is likelythat these types of images will be available from most machines inthe near future. The exact role of this technology in the urologicalimaging armamentarium will need to be discussed at length, partic-ularly with the concerns about the amount of radiation exposurerequired. Presently 3-D reconstructive techniques are used exten-sively for preoperative planning of open and laparoscopic renal pa-renchymal surgery. Virtual endoscopy is likely to be just as valuableas a preoperative planning tool for renoscopy and perhaps will formthe basis of the surgical simulators of the near future.

Ken Anson and Roger KirbyDepartment of UrologySt George’s HospitalLondon, United Kingdom

URETEROPELVIC JUNCTION OBSTRUCTION AND METALLIC STENTS2386