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Endocrine function of hypothalamo-hypophyseal system Matilda Meinshausen Group 1 Academic Year 2015/2016 Charles University of Prague 2 nd Faculty of Medicine Physiology

Endocrine function of hypothalamo-hypophyseal systemphysiology.lf2.cuni.cz/teaching/prezentace studentu/Endocrine... · Endocrine function of hypothalamo-hypophyseal system Matilda

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Page 1: Endocrine function of hypothalamo-hypophyseal systemphysiology.lf2.cuni.cz/teaching/prezentace studentu/Endocrine... · Endocrine function of hypothalamo-hypophyseal system Matilda

Endocrine function of hypothalamo-hypophyseal

system

Matilda Meinshausen Group 1

Academic Year 2015/2016

Charles University of Prague 2nd Faculty of Medicine

Physiology

Page 2: Endocrine function of hypothalamo-hypophyseal systemphysiology.lf2.cuni.cz/teaching/prezentace studentu/Endocrine... · Endocrine function of hypothalamo-hypophyseal system Matilda

Hypothalamus and hypophysis

Page 3: Endocrine function of hypothalamo-hypophyseal systemphysiology.lf2.cuni.cz/teaching/prezentace studentu/Endocrine... · Endocrine function of hypothalamo-hypophyseal system Matilda

Hypothalamus and posterior pituitary

! Neural connections

! Hormones : ADH + oxytocin (neuropeptides)

!  ADH = primarily associated w/ supraoptic ncl

! Oxytocin = primarily associated w/ paraventricular ncl

Page 4: Endocrine function of hypothalamo-hypophyseal systemphysiology.lf2.cuni.cz/teaching/prezentace studentu/Endocrine... · Endocrine function of hypothalamo-hypophyseal system Matilda

Control of hormonal secretion

Page 5: Endocrine function of hypothalamo-hypophyseal systemphysiology.lf2.cuni.cz/teaching/prezentace studentu/Endocrine... · Endocrine function of hypothalamo-hypophyseal system Matilda

Hypothalamus and anterior pituitary !  Secretes 6 peptide

hormones:

! Hypothalamus and ant. pituitary linked directly by hypothalamic-hypophyseal portal system

•  TSH •  FSH •  LH •  Growth

hormone •  Prolactin •  ACTH

Page 6: Endocrine function of hypothalamo-hypophyseal systemphysiology.lf2.cuni.cz/teaching/prezentace studentu/Endocrine... · Endocrine function of hypothalamo-hypophyseal system Matilda

Anterior lobe hormones

Page 7: Endocrine function of hypothalamo-hypophyseal systemphysiology.lf2.cuni.cz/teaching/prezentace studentu/Endocrine... · Endocrine function of hypothalamo-hypophyseal system Matilda

Hormone functions

Hormones

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1. Hormones synthesized by cell

bodies in the hypothalamus

Paraventricular nucleus

Neural Connection

Vascular Connection

Hypothalamic hormone control

secretion

Inhibitory Factors

Releasing Factors

Conducted through: Hypothalamic-hypophyseal

portal vessels

2. To Target Glands

Supraoptic nucleus

2. To General Circulation

1. Hormones synthesized by cells

in hypophysis

Nerve Fibers: Hypothalamic-hypophyseal tract

Overview

Page 9: Endocrine function of hypothalamo-hypophyseal systemphysiology.lf2.cuni.cz/teaching/prezentace studentu/Endocrine... · Endocrine function of hypothalamo-hypophyseal system Matilda
Page 10: Endocrine function of hypothalamo-hypophyseal systemphysiology.lf2.cuni.cz/teaching/prezentace studentu/Endocrine... · Endocrine function of hypothalamo-hypophyseal system Matilda
Page 11: Endocrine function of hypothalamo-hypophyseal systemphysiology.lf2.cuni.cz/teaching/prezentace studentu/Endocrine... · Endocrine function of hypothalamo-hypophyseal system Matilda

References

!  Constanzo, Linda (2011): Physiology. 5th edition, Lippincott Williams & Wilkins.

!  Hall, John Edward, and Arthur C. Guyton. Guyton And Hall Textbook Of Medical Physiology. 12th ed. Philadelphia: W.B. Saunders Company, 2006. Print.

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Thank you for your attention!