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1 Copyright © 2018 Pearson Education, Inc.
Fundamentals of Anatomy and Physiology, 11e (Martini)
Chapter 3 The Cellular Level of Organization
Multiple Choice Questions
1) What is an advantage of the electron microscope over the compound light microscope?
A) It can function in complete darkness.
B) It is older, more reliable technology.
C) It is less expensive.
D) It allows much greater magnification of a specimen.
E) It is portable.
Answer: D
Learning Outcome: 3-1
Bloom's Taxonomy: Understanding
2) The smallest living unit within the human body is
A) a protein.
B) a cell.
C) a tissue.
D) an organ.
E) an organ system.
Answer: B
Learning Outcome: 3-1
Bloom's Taxonomy: Remembering
3) The cell theory includes all of these concepts except
A) each cell maintains homeostasis at the cellular level.
B) cells are the smallest units that carry out the essential functions of life.
C) cells are the building blocks of all organisms.
D) all cells come from the division of preexisting cells.
E) every cell is capable of living on its own if isolated from the body.
Answer: E
Learning Outcome: 3-1
Bloom's Taxonomy: Understanding
4) The only kind of cell in the body that is not produced by the division of preexisting cells is
A) a gamete (sperm or egg cell).
B) a neuron (nerve cell).
C) an osteocyte (bone cell).
D) none, because every cell is produced by the division of another cell.
E) a liver cell.
Answer: D
Learning Outcome: 3-1
Bloom's Taxonomy: Understanding
2 Copyright © 2018 Pearson Education, Inc.
5) What would be an example of a cell maintaining homeostasis at the cellular level?
A) a cell of the intestine secretes digestive enzymes
B) a muscle cell contracts
C) a sperm fertilizes an egg
D) a cell takes up potassium to maintain the proper cytoplasmic potassium concentration
E) a cell divides to become two cells
Answer: D
Learning Outcome: 3-1
Bloom's Taxonomy: Understanding
6) Cytology is the study of
A) biological macromolecules.
B) causes and treatment of cancer.
C) the origins of life on Earth.
D) genes and their function.
E) the structure and function of cells.
Answer: E
Learning Outcome: 3-1
Bloom's Taxonomy: Remembering
7) ________ cells are all of the cells of the body except the reproductive cells (sperm and
oocytes).
A) Core
B) Somatic
C) Corpus
D) Main
E) Primary
Answer: B
Learning Outcome: 3-1
Bloom's Taxonomy: Remembering
8) Most cells have only one
A) nucleus.
B) ribosome.
C) peroxisome.
D) lysosome.
E) mitochondrion.
Answer: A
Learning Outcome: 3-1
Bloom's Taxonomy: Remembering
3 Copyright © 2018 Pearson Education, Inc.
9) The extracellular fluid in most tissues is called ________ fluid.
A) interstitial
B) cytosolic
C) cytoplasmic
D) outside
E) peripheral
Answer: A
Learning Outcome: 3-1
Bloom's Taxonomy: Remembering
10) What is a structure that separates the contents of a human cell from its surrounding medium?
A) cell wall
B) tissue
C) plasma membrane
D) skin
E) nucleus
Answer: C
Learning Outcome: 3-1
Bloom's Taxonomy: Remembering
11) If a hole is torn in a cell's plasma membrane, the cell will die because
A) it will not be able to maintain differences between the cytoplasm and extracellular fluid.
B) germs are attracted toward cytoplasm leaking from a cell.
C) it will not be able to undergo cell division.
D) its chromosomes will not be held in place.
E) cells can only make more plasma membrane during cell division.
Answer: A
Learning Outcome: 3-1
Bloom's Taxonomy: Understanding
12) What is the first part of the cell that is affected when the pH of extracellular fluid changes?
A) the nucleus
B) the nucleolus
C) the cytosol
D) the plasma membrane
E) the cytoskeleton
Answer: D
Learning Outcome: 3-1
Bloom's Taxonomy: Understanding
4 Copyright © 2018 Pearson Education, Inc.
13) How is the plasma membrane involved in structural support of body tissues?
A) It has specialized connections to other cells or extracellular materials.
B) It primarily consists of fibrous proteins.
C) It is inflated by cytoplasm at high pressure.
D) Tissues are largely composed of empty plasma membranes left by dead cells.
E) It is hydrophobic, so it repels extracellular fluid and attracts the membranes of other cells.
Answer: A
Learning Outcome: 3-1
Bloom's Taxonomy: Remembering
14) Functions of the plasma membrane include all of the following except
A) separation of the cytoplasm from the extracellular fluid.
B) regulation of exchange of materials with the extracellular environment.
C) sensitivity to chemical changes in the extracellular fluid.
D) thermal insulation.
E) structural support.
Answer: D
Learning Outcome: 3-1
Bloom's Taxonomy: Remembering
15) Which of the following is not a function of membrane proteins?
A) bind to ligands
B) regulate the passage of ions
C) act as carrier molecules for various solutes
D) act as anchors or stabilizers for the cell membrane
E) store cellular nutrients
Answer: E
Learning Outcome: 3-1
Bloom's Taxonomy: Remembering
16) Most of the surface area of a plasma membrane consists of
A) a protein bilayer.
B) a phospholipid bilayer.
C) carbohydrate molecules.
D) DNA.
E) cells.
Answer: B
Learning Outcome: 3-1
Bloom's Taxonomy: Remembering
5 Copyright © 2018 Pearson Education, Inc.
17) The tails of a phospholipid molecule in a plasma membrane are
A) hydrophilic.
B) composed of amino acids.
C) hydrophobic.
D) facing the cytosol.
E) interlocked to provide membrane strength.
Answer: C
Learning Outcome: 3-1
Bloom's Taxonomy: Remembering
18) The plasma membrane does not include
A) integral proteins.
B) glycolipids.
C) phospholipids.
D) cholesterol.
E) silk mesh.
Answer: E
Learning Outcome: 3-1
Bloom's Taxonomy: Remembering
19) Identify the role of cholesterol in the plasma membrane.
A) enables ions to pass
B) forms enzymes
C) reduces membrane fluidity and permeability
D) anchors the phospholipids
E) provides energy
Answer: C
Learning Outcome: 3-1
Bloom's Taxonomy: Understanding
6 Copyright © 2018 Pearson Education, Inc.
Figure 3-1 The Plasma membrane
Use Figure 3-1 to answer the following questions.
20) What part of the plasma membrane is hydrophobic?
A) 2
B) 3
C) 4
D) 5
E) 6
Answer: B
Learning Outcome: 3-1
Bloom's Taxonomy: Understanding
7 Copyright © 2018 Pearson Education, Inc.
21) Which structure is water most likely to pass through?
A) 1
B) 2
C) 3
D) 4
E) 8
Answer: B
Learning Outcome: 3-1
Bloom's Taxonomy: Understanding
22) Which structure has a "gate" to control transport?
A) 1
B) 2
C) 4
D) 7
E) 8
Answer: E
Learning Outcome: 3-1
Bloom's Taxonomy: Understanding
23) Microfilaments are labeled
A) 1.
B) 2.
C) 3.
D) 5.
E) 6.
Answer: D
Learning Outcome: 3-1
Bloom's Taxonomy: Remembering
24) Membrane proteins perform all of the following functions except
A) anchoring the cell to other structures.
B) binding to extracellular ligands.
C) transporting solutes across the membrane.
D) catalyzing chemical reactions.
E) metabolizing glucose to gain energy.
Answer: E
Learning Outcome: 3-1
Bloom's Taxonomy: Understanding
8 Copyright © 2018 Pearson Education, Inc.
25) Identify the mismatched pair.
A) receptor proteins—bind to extracellular ligands
B) channel proteins—provide passageway for ions
C) recognition glycoproteins and glycolipids—identify the cell as "self"
D) carrier proteins—allow a cell to move
E) enzymes—speed up chemical reactions
Answer: D
Learning Outcome: 3-1
Bloom's Taxonomy: Understanding
26) Proteins of the plasma membrane carry out all of the following functions except
A) binding to DNA to turn on genes.
B) sending and receiving signals to and from other cells.
C) transporting substances across the membrane.
D) anchoring the cell to external structures.
E) catalyzing chemical reactions at the inner or outer surface of the membrane.
Answer: A
Learning Outcome: 3-1
Bloom's Taxonomy: Understanding
27) Receptor molecules on the surface of cells bind specific molecules called, in general,
A) recognizers.
B) binders.
C) ligands.
D) bonders.
E) reactants.
Answer: C
Learning Outcome: 3-1
Bloom's Taxonomy: Remembering
28) Water and small hydrophilic solutes
A) may pass through the phospholipid bilayer of the plasma membrane.
B) cannot pass through a plasma membrane.
C) can dissolve holes in the plasma membrane.
D) may pass through channels in the plasma membrane.
E) do not mix with each other.
Answer: D
Learning Outcome: 3-1
Bloom's Taxonomy: Applying
9 Copyright © 2018 Pearson Education, Inc.
29) The watery component of the cytoplasm is called
A) cytosol.
B) protoplasm.
C) extracellular fluid.
D) interstitial fluid.
E) matrix.
Answer: A
Learning Outcome: 3-2
Bloom's Taxonomy: Remembering
30) Which of the following descriptors regarding cytoplasm is false?
A) contains less protein than extracellular fluid
B) the material that fills a cell
C) syrupy or gel-like consistency
D) includes cytoskeleton
E) includes cytosol
Answer: A
Learning Outcome: 3-2
Bloom's Taxonomy: Remembering
31) Many proteins in the cytosol are ________ that accelerate metabolic reactions.
A) carbohydrates
B) enzymes
C) lipids
D) messengers
E) ions
Answer: B
Learning Outcome: 3-2
Bloom's Taxonomy: Remembering
32) Compared to the extracellular fluid, cytosol contains
A) a higher concentration of potassium ions.
B) a lower concentration of dissolved proteins.
C) almost no glycogen.
D) a higher concentration of amino acids.
E) almost no lipids.
Answer: A
Learning Outcome: 3-2
Bloom's Taxonomy: Remembering
10 Copyright © 2018 Pearson Education, Inc.
33) The cytoplasm contains the fluid cytosol, insoluble inclusions, and the
A) microvilli.
B) nucleolus.
C) enzymes.
D) organelles.
E) cilia.
Answer: D
Learning Outcome: 3-2
Bloom's Taxonomy: Remembering
34) Masses of insoluble material that are sometimes found in cytosol are known as
A) colloids.
B) emulsifiers.
C) solutes.
D) crystals.
E) inclusions.
Answer: E
Learning Outcome: 3-2
Bloom's Taxonomy: Remembering
35) The endoplasmic reticulum is an example of a(n) ________ organelle.
A) filamentous
B) extracellular
C) interstitial
D) membranous
E) bound
Answer: D
Learning Outcome: 3-2
Bloom's Taxonomy: Remembering
36) ________ are compartments within the cell whose contents are isolated from the cytosol.
A) Cytoskeleton
B) Microvilli
C) Nonmembranous organelles
D) Membranous organelles
E) Ribosomes
Answer: D
Learning Outcome: 3-2
Bloom's Taxonomy: Understanding
11 Copyright © 2018 Pearson Education, Inc.
37) Each of the following is an example of a nonmembranous organelle except
A) lysosomes.
B) cilia.
C) centrioles.
D) ribosomes.
E) cytoskeleton.
Answer: A
Learning Outcome: 3-2
Bloom's Taxonomy: Remembering
38) Match the organelle (1-4) with the correct description (5-8).
1) mitochondrion 5) synthesizing molecules
2) centriole 6) liquid in cell
3) endoplasmic reticulum 7) provides cell with energy
4) cytosol 8) aids the formation of the spindle apparatus
A) 1 and 7, 2 and 6, 3 and 8, 4 and 5
B) 1 and 8, 2 and 5, 3 and 6, 4 and 7
C) 1 and 7, 2 and 8, 3 and 5, 4 and 6
D) 1 and 5, 2 and 6, 3 and 7, 4 and 8
E) 1 and 6, 2 and 8, 3 and 5, 4 and 7
Answer: C
Learning Outcome: 3-2
Bloom's Taxonomy: Remembering
39) Tubulin is to microtubules as actin is to
A) ribosomes.
B) microfilaments.
C) intermediate filaments.
D) flagella.
E) microvilli.
Answer: B
Learning Outcome: 3-2
Bloom's Taxonomy: Understanding
40) Microfilaments do not
A) anchor the cytoskeleton to membrane proteins.
B) help determine the consistency of cytoplasm.
C) produce cell movement, with myosin.
D) consist of the protein called actin.
E) distribute chromosomes to opposite ends of a dividing cell.
Answer: E
Learning Outcome: 3-2
Bloom's Taxonomy: Remembering
12 Copyright © 2018 Pearson Education, Inc.
41) Microfilaments
A) are usually composed of myosin.
B) are hollow, filamentous structures.
C) anchor the cytoskeleton to integral proteins of the cell membrane.
D) interact with filaments composed of tubulin to produce muscle contractions.
E) are found in the cytoplasm radiating away from the centrosome.
Answer: C
Learning Outcome: 3-2
Bloom's Taxonomy: Remembering
42) Which of the following cytoskeleton components moves the chromosomes during cell
division?
A) microfilaments
B) intermediate filaments
C) thick filaments
D) microtubules
E) basal bodies
Answer: D
Learning Outcome: 3-2
Bloom's Taxonomy: Remembering
43) Which of following properties of microtubules is correct?
A) made of myosin
B) made of actin
C) found only in the terminal web
D) another term for microfilaments
E) interact with dynein and kinesin
Answer: E
Learning Outcome: 3-2
Bloom's Taxonomy: Remembering
44) Which of following properties of the cytoskeleton is incorrect?
A) supports organelles
B) controls cell shape
C) provides cell strength
D) connects cells to each other
E) moves organelles
Answer: D
Learning Outcome: 3-2
Bloom's Taxonomy: Understanding
13 Copyright © 2018 Pearson Education, Inc.
Figure 3-2 The Anatomy of a Representative Cell
Use Figure 3-2 to answer the following questions:
45) The structure labeled "1" permits the cell to
A) attach to neighboring cells.
B) produce more cells.
C) increase its surface area for increased absorption.
D) swim in extracellular fluid.
E) trap bacteria.
Answer: C
Learning Outcome: 3-2
Bloom's Taxonomy: Understanding
14 Copyright © 2018 Pearson Education, Inc.
46) Which structure organizes the mitotic spindle during cell division?
A) 1
B) 2
C) 3
D) 5
E) 6
Answer: B
Learning Outcome: 3-2
Bloom's Taxonomy: Understanding
47) Synthesis of carbohydrates and lipids occurs in the structure labeled
A) 4.
B) 5.
C) 6.
D) 7.
E) 8.
Answer: D
Learning Outcome: 3-2
Bloom's Taxonomy: Understanding
48) Which organelle renews the cell membrane and modifies and packages proteins for
secretion?
A) 4
B) 5
C) 6
D) 7
E) 8
Answer: C
Learning Outcome: 3-2
Bloom's Taxonomy: Understanding
49) Which structure produces ATP for the cell?
A) 1
B) 2
C) 3
D) 5
E) 6
Answer: C
Learning Outcome: 3-2
Bloom's Taxonomy: Understanding
15 Copyright © 2018 Pearson Education, Inc.
50) Microvilli are found on cells of the inner surface of the small intestine, where they
A) slow the movement of food through the digestive tract.
B) increase the absorption of nutrients from digested food.
C) sense the presence of food in the digestive tract.
D) push food along the digestive tract.
E) protect the intestinal lining from irritants or toxins in the food.
Answer: B
Learning Outcome: 3-2
Bloom's Taxonomy: Applying
51) If an animal cell lacked centrioles, it would not be able to
A) move.
B) synthesize proteins.
C) produce DNA.
D) metabolize sugars.
E) divide.
Answer: E
Learning Outcome: 3-2
Bloom's Taxonomy: Understanding
52) The ________ is the microtubule organizing center of the cell.
A) flagellum
B) ribosome
C) nucleus
D) centrosome
E) plasma membrane
Answer: D
Learning Outcome: 3-2
Bloom's Taxonomy: Remembering
53) Centrioles form the basal bodies that anchor microtubules within cilia and
A) flagella.
B) microfilaments.
C) microvilli.
D) ribosomes.
E) chromosomes.
Answer: A
Learning Outcome: 3-2
Bloom's Taxonomy: Remembering
16 Copyright © 2018 Pearson Education, Inc.
54) Cilia and flagella contain nine pairs of ________ surrounding a central pair.
A) microvilli
B) microfilaments
C) microsomes
D) microtubules
E) intermediate filaments
Answer: D
Learning Outcome: 3-2
Bloom's Taxonomy: Remembering
55) Motile cilia move fluids across a cell's surface, while a flagellum
A) cools a cell.
B) is not motile.
C) fastens one cell to another.
D) propels a cell through fluid.
E) detects environmental stimuli.
Answer: D
Learning Outcome: 3-2
Bloom's Taxonomy: Understanding
56) ________ may be scattered in the cytoplasm or bound to endoplasmic reticulum.
A) Mitochondria
B) Ribosomes
C) Vesicles
D) Proteosomes
E) Nuclei
Answer: B
Learning Outcome: 3-2
Bloom's Taxonomy: Understanding
57) Ribosomes are composed of protein and
A) glycogen.
B) rRNA.
C) ATP.
D) DNA.
E) steroids.
Answer: B
Learning Outcome: 3-2
Bloom's Taxonomy: Remembering
17 Copyright © 2018 Pearson Education, Inc.
58) The "r" in rRNA stands for
A) regeneration.
B) recurrence.
C) rebuilding.
D) ribosomal.
E) radiation.
Answer: D
Learning Outcome: 3-2
Bloom's Taxonomy: Remembering
59) ________ are responsible for identifying and digesting damaged or denatured proteins.
A) Peroxisomes
B) Proteasomes
C) Lysosomes
D) Endosomes
E) Nucleosomes
Answer: B
Learning Outcome: 3-2
Bloom's Taxonomy: Remembering
60) Proteosomes ________ proteins that have been damaged or denatured.
A) tag for destruction by a different organelle
B) break down
C) expel from the cell
D) repair
E) duplicate
Answer: B
Learning Outcome: 3-2
Bloom's Taxonomy: Understanding
61) Synthesis of lipids and glycogen takes place at the
A) ribosomes.
B) rough ER.
C) smooth ER.
D) Golgi apparatus.
E) mitochondria.
Answer: C
Learning Outcome: 3-2
Bloom's Taxonomy: Remembering
18 Copyright © 2018 Pearson Education, Inc.
62) Which of the following consists of a network of intracellular membranes with attached
ribosomes?
A) rough endoplasmic reticulum
B) smooth endoplasmic reticulum
C) mitochondria
D) nucleoli
E) Golgi apparatus
Answer: A
Learning Outcome: 3-2
Bloom's Taxonomy: Remembering
63) Which form of endoplasmic reticulum modifies and packages newly synthesized proteins?
A) all forms of endoplasmic reticulum
B) simple endoplasmic reticulum
C) raised endoplasmic reticulum
D) smooth endoplasmic reticulum
E) rough endoplasmic reticulum
Answer: E
Learning Outcome: 3-2
Bloom's Taxonomy: Remembering
64) The endoplasmic reticulum is responsible for all of the following except
A) drug and toxin neutralization.
B) lipid synthesis.
C) modification of new proteins.
D) passing molecules to the Golgi apparatus.
E) housing the chromosomes.
Answer: E
Learning Outcome: 3-2
Bloom's Taxonomy: Remembering
65) Each of the following is a function of smooth endoplasmic reticulum except
A) storage and release of calcium ions.
B) synthesis of protein.
C) synthesis of steroid hormones.
D) synthesis of triglycerides.
E) detoxification of drugs.
Answer: B
Learning Outcome: 3-2
Bloom's Taxonomy: Understanding
19 Copyright © 2018 Pearson Education, Inc.
66) Examination of a sample of glandular cells reveals an extensive network of smooth
endoplasmic reticulum. Which of the following is the likeliest product of these cells?
A) digestive enzymes
B) steroid hormones
C) protein hormones
D) transport proteins
E) antibodies
Answer: B
Learning Outcome: 3-2
Bloom's Taxonomy: Applying
67) Which of the following statements about the Golgi apparatus is false?
A) It receives transport vesicles from the RER.
B) It sends transport vesicles to the RER.
C) It produces lysosomes.
D) It supplies new membrane components.
E) It produces secretory vesicles.
Answer: B
Learning Outcome: 3-2
Bloom's Taxonomy: Understanding
68) The following is a list of the steps involved in the process of secretion by the Golgi
apparatus. What is the proper order for these steps?
1. Cisternae move from the forming face toward the maturing face.
2. Exocytosis
3. Products from RER are packaged into transport vesicles.
4. Secretory vesicles are formed at the maturing face.
5. Vesicles arrive at the forming face.
6. Enzymes modify arriving proteins and glycoproteins.
A) 5, 6, 1, 4, 2, 3
B) 2, 3, 5, 6, 1, 4
C) 4, 3, 1, 6, 5, 2
D) 3, 5, 6, 1, 4, 2
E) 1, 3, 6, 4, 2, 5
Answer: D
Learning Outcome: 3-2
Bloom's Taxonomy: Understanding
69) The ________ typically consists of five or six flattened membranous discs called cisternae.
A) centrioles
B) rough endoplasmic reticulum
C) Golgi apparatus
D) smooth endoplasmic reticulum
E) mitochondria
Answer: C
Learning Outcome: 3-2
Bloom's Taxonomy: Remembering
20 Copyright © 2018 Pearson Education, Inc.
70) When activated, lysosomes function in
A) formation of new cell membranes.
B) synthesis of proteins.
C) digestion of materials.
D) synthesis of lipids.
E) cell division.
Answer: C
Learning Outcome: 3-2
Bloom's Taxonomy: Remembering
71) Macrophages are cells that engulf and consume germs or debris. What organelle must be
especially plentiful in these cells?
A) centrioles
B) lysosomes
C) mitochondria
D) ribosomes
E) nuclei
Answer: B
Learning Outcome: 3-2
Bloom's Taxonomy: Understanding
72) Peroxisomes
A) both generate and break down hydrogen peroxide.
B) pull the chromosomes toward the poles of a dividing cell.
C) manufacture proteins.
D) manufacture most of a cell's ATP.
E) contain the genetic information of a cell.
Answer: A
Learning Outcome: 3-2
Bloom's Taxonomy: Remembering
73) Organelles that break down fatty acids and hydrogen peroxide are
A) lysosomes.
B) peroxisomes.
C) endocytic vesicles.
D) nuclei.
E) toxisomes.
Answer: B
Learning Outcome: 3-2
Bloom's Taxonomy: Remembering
21 Copyright © 2018 Pearson Education, Inc.
74) What is the source of new material for the plasma membrane?
A) microtubules
B) mitochondria
C) rough endoplasmic reticulum
D) ribosomes
E) Golgi apparatus
Answer: E
Learning Outcome: 3-2
Bloom's Taxonomy: Understanding
75) In addition to secreting products from the cell, vesicles produced by the Golgi apparatus can
A) house chromosomes.
B) produce ATP.
C) synthesize proteins.
D) add new material to the plasma membrane.
E) transport materials to the endoplasmic reticulum.
Answer: D
Learning Outcome: 3-2
Bloom's Taxonomy: Understanding
76) Which of the following statements concerning mitochondria is false?
A) The cristae increase the inner surface area of the organelle.
B) The matrix contains metabolic enzymes involved in ATP synthesis.
C) Respiratory enzymes are attached to the surface of the cristae.
D) The mitochondria produce oxygen in the process of energy transformation.
E) The mitochondria produce most of a cell's ATP.
Answer: D
Learning Outcome: 3-2
Bloom's Taxonomy: Understanding
77) Some cells contain large numbers of mitochondria while others have relatively few or none.
This suggests that
A) cells with large numbers of mitochondria are short-lived.
B) cells with large numbers of mitochondria have a high energy demand.
C) cells with small numbers of mitochondria have a large ATP supply.
D) cells with large numbers of mitochondria have a low energy demand.
E) some cells are older than others.
Answer: B
Learning Outcome: 3-2
Bloom's Taxonomy: Applying
22 Copyright © 2018 Pearson Education, Inc.
78) Most of the ATP required to power cellular operations is produced in the
A) cytoplasm.
B) endoplasmic reticulum.
C) nucleus.
D) mitochondria.
E) cilia.
Answer: D
Learning Outcome: 3-2
Bloom's Taxonomy: Remembering
79) Most of a cell's DNA is located in its
A) ribosomes.
B) lysosomes.
C) Golgi apparatus.
D) nucleus.
E) nucleolus.
Answer: D
Learning Outcome: 3-3
Bloom's Taxonomy: Remembering
80) The control center for cellular operations is the
A) nucleus.
B) mitochondria.
C) Golgi apparatus.
D) endoplasmic reticulum.
E) ribosome.
Answer: A
Learning Outcome: 3-3
Bloom's Taxonomy: Remembering
81) A mature red blood cell lacks a nucleus; therefore, it
A) can repair itself readily.
B) is malformed.
C) can only divide once more.
D) will be a long-lived cell.
E) cannot make new proteins and will be worn out within a few months.
Answer: E
Learning Outcome: 3-3
Bloom's Taxonomy: Applying
23 Copyright © 2018 Pearson Education, Inc.
82) The nucleus is surrounded by the
A) plasma membrane.
B) membranous sac.
C) phospholipid bilayer.
D) nuclear envelope.
E) chromosome shield.
Answer: D
Learning Outcome: 3-3
Bloom's Taxonomy: Remembering
83) Which organelle is more prominent in cells that make large amounts of protein?
A) nucleus
B) nucleolus
C) chromosome
D) proteasome
E) mitochondria
Answer: B
Learning Outcome: 3-3
Bloom's Taxonomy: Understanding
84) The components of ribosomes are formed within
A) the endoplasmic reticulum.
B) Golgi complexes.
C) lysosomes.
D) mitochondria.
E) nucleoli.
Answer: E
Learning Outcome: 3-3
Bloom's Taxonomy: Remembering
85) Histones are found in
A) nucleosomes.
B) proteasomes.
C) lysosomes.
D) vesicles.
E) endosomes.
Answer: A
Learning Outcome: 3-3
Bloom's Taxonomy: Remembering
24 Copyright © 2018 Pearson Education, Inc.
86) Chromosomes consist of ________ and ________.
A) RNA; carbohydrates
B) DNA; lipids
C) DNA; proteins
D) water; RNA
E) RNA; proteins
Answer: C
Learning Outcome: 3-3
Bloom's Taxonomy: Remembering
87) In cells that are not dividing, chromosomes uncoil to form a tangle of fine fibers known as
A) histones.
B) histiocytes.
C) chromatin.
D) chromaffin.
E) genes.
Answer: C
Learning Outcome: 3-3
Bloom's Taxonomy: Remembering
88) How do chromosomes become visible under a light microscope as a cell prepares to divide?
A) The cell becomes flat and thin, and its internal structures become easier to see.
B) Thin strands of chromatin coil tightly and then coil again.
C) DNA is thicker after it has replicated.
D) Chromosomes become more intensely colored before cell division.
E) Chromosomes are created before cell division, and then broken down afterward.
Answer: B
Learning Outcome: 3-3
Bloom's Taxonomy: Understanding
89) Each triplet of bases in a gene corresponds to
A) one amino acid in a protein.
B) one DNA nucleotide.
C) one protein.
D) one mRNA.
E) one chromosome.
Answer: A
Learning Outcome: 3-3
Bloom's Taxonomy: Remembering
25 Copyright © 2018 Pearson Education, Inc.
90) The functional units of DNA that contain the instructions for making one or more proteins
are
A) chromosomes.
B) genes.
C) ribosomes.
D) codons.
E) RNA.
Answer: B
Learning Outcome: 3-3
Bloom's Taxonomy: Remembering
91) A gene is a set of specific instructions that
A) produces amino acids for proteins.
B) copies DNA strands for mitosis.
C) controls the process of mitosis.
D) indicates the sequence of amino acids in a protein molecule.
E) directs carbohydrate synthesis.
Answer: D
Learning Outcome: 3-3
Bloom's Taxonomy: Understanding
92) Which of the following is false about DNA fingerprinting?
A) determined by analyzing proteins
B) unique to each individual with the exception of identical twins
C) used extensively during crime scene investigations
D) may be obtained from blood, semen, hair, and other tissues
E) based on short tandem repeats (STRs) in the DNA
Answer: A
Learning Outcome: 3-3
Bloom's Taxonomy: Understanding
93) The "m" in mRNA stands for
A) messenger.
B) modifier.
C) metabolic.
D) molecular.
E) matching.
Answer: A
Learning Outcome: 3-4
Bloom's Taxonomy: Remembering
26 Copyright © 2018 Pearson Education, Inc.
94) The enzyme ________ is required for the synthesis of mRNA.
A) RNA polymerase
B) deoxyribase
C) phosphatase
D) RNA synthetase
E) ribase
Answer: A
Learning Outcome: 3-4
Bloom's Taxonomy: Remembering
95) The process of forming mRNA is called
A) replication.
B) transcription.
C) translation.
D) ribolation.
E) auscultation.
Answer: B
Learning Outcome: 3-4
Bloom's Taxonomy: Remembering
96) The start of each gene begins with a(n) ________ segment.
A) neocodon
B) intron
C) histone
D) promoter
E) boosting
Answer: D
Learning Outcome: 3-4
Bloom's Taxonomy: Remembering
97) Thymine is replaced by which nitrogen base in RNA?
A) ribose
B) uracil
C) guanine
D) thymine is not replaced in RNA
E) cytosine
Answer: B
Learning Outcome: 3-4
Bloom's Taxonomy: Understanding
27 Copyright © 2018 Pearson Education, Inc.
98) The mRNA sequence that is complementary to the sequence ATC on DNA is
A) ATC.
B) TAG.
C) UAG.
D) AUG.
E) AUC.
Answer: C
Learning Outcome: 3-4
Bloom's Taxonomy: Understanding
99) Before the mRNA transcribed from a gene can be used to translate into a protein, it must be
A) edited to remove introns.
B) edited to remove exons.
C) transported into the cytoplasm.
D) edited to remove introns and transported into the cytoplasm.
E) coated with phospholipids for transport out of the nucleus.
Answer: D
Learning Outcome: 3-4
Bloom's Taxonomy: Understanding
100) Transfer of mRNA from the nucleus to the cytosol occurs through
A) carrier proteins.
B) gap junctions.
C) nucleosides.
D) gap lines.
E) nuclear pores.
Answer: E
Learning Outcome: 3-4
Bloom's Taxonomy: Remembering
101) mRNA is needed to synthesize ________ in the cytoplasm.
A) carbohydrates
B) lipids
C) proteins
D) phospholipids
E) salts
Answer: C
Learning Outcome: 3-4
Bloom's Taxonomy: Remembering
28 Copyright © 2018 Pearson Education, Inc.
102) A molecule of ________ contains all the codons needed to produce a particular
polypeptide.
A) rRNA
B) mRNA
C) dRNA
D) tRNA
E) cRNA
Answer: B
Learning Outcome: 3-4
Bloom's Taxonomy: Remembering
103) The process of protein formation directed by mRNA is called
A) replication.
B) transcription.
C) translation.
D) mitosis.
E) auscultation.
Answer: C
Learning Outcome: 3-4
Bloom's Taxonomy: Remembering
104) The anticodon for the triplet UCA is
A) AGU.
B) AGC.
C) TCA.
D) TGT.
E) AGT.
Answer: A
Learning Outcome: 3-4
Bloom's Taxonomy: Understanding
105) During protein synthesis, amino acids are assembled in the proper sequence because each
tRNA has a(n) ________ that binds to the next codon in the mRNA.
A) enzyme
B) nucleotide
C) anticodon
D) promotor
E) transporter
Answer: C
Learning Outcome: 3-4
Bloom's Taxonomy: Remembering
29 Copyright © 2018 Pearson Education, Inc.
106) Amino acids are transferred to the ribosome to be incorporated into a growing polypeptide
chain by
A) aRNA.
B) mRNA.
C) rRNA.
D) tRNA.
E) pRNA.
Answer: D
Learning Outcome: 3-4
Bloom's Taxonomy: Remembering
107) The "t" in tRNA stands for
A) translate.
B) transport.
C) transfer.
D) transcribe.
E) transmit.
Answer: C
Learning Outcome: 3-4
Bloom's Taxonomy: Remembering
108) What is the correct order of occurrence for the steps of protein synthesis?
1. mRNA is produced in nucleus.
2. Ribosome moves along mRNA.
3. DNA uncoils for transcription.
4. Polypeptide is produced.
5. tRNA brings amino acids to ribosome.
6. mRNA moves to ribosome.
A) 3, 1, 6, 2, 5, 4
B) 2, 4, 6, 1, 3, 5
C) 2, 1, 5, 4, 3, 6
D) 3, 5, 1, 6, 2, 4
E) 1, 5, 3, 4, 2, 6
Answer: A
Learning Outcome: 3-4
Bloom's Taxonomy: Understanding
109) The duplication of DNA is called ________, the copying of DNA to mRNA is called
________, and the reading of the mRNA by the cell to make a protein is called ________.
A) replication; transcription; translation
B) interphase; replication; active transport
C) replication; translation; transcription
D) mitosis; duplication; protein synthesis
E) reproduction; duplication; initiation
Answer: A
Learning Outcome: 3-4
Bloom's Taxonomy: Understanding
30 Copyright © 2018 Pearson Education, Inc.
110) Permanent alterations in a cell's DNA that affect the nucleotide sequence of one or more
genes are called
A) interferons.
B) mutations.
C) reconstructions.
D) polymorphs.
E) changelings.
Answer: B
Learning Outcome: 3-4
Bloom's Taxonomy: Remembering
111) The ________ of a cell membrane indicates how easy it is for substances to cross.
A) thickness
B) pliability
C) density
D) permeability
E) charge
Answer: D
Learning Outcome: 3-5
Bloom's Taxonomy: Remembering
112) Cell membranes are said to be ________ because they allow some substances to pass but
not others.
A) impermeable
B) doubly amphipathic
C) hydrophilic
D) selectively permeable
E) hydrophobic
Answer: D
Learning Outcome: 3-5
Bloom's Taxonomy: Remembering
113) A cell can increase how fast a substance diffuses across its plasma membrane by inserting
channels, which modify the
A) distance across the membrane.
B) concentration gradient of the substance.
C) size and mobility of the substance.
D) membrane's permeability to the substance.
E) charge of the substance.
Answer: D
Learning Outcome: 3-5
Bloom's Taxonomy: Understanding
31 Copyright © 2018 Pearson Education, Inc.
114) The movement of oxygen from an area of high concentration to an area of low
concentration is an example of
A) osmosis.
B) active transport.
C) diffusion.
D) facilitated transport.
E) filtration.
Answer: C
Learning Outcome: 3-5
Bloom's Taxonomy: Remembering
115) Breathing faster and deeper eliminates more carbon dioxide from the body than normal
breathing. Under these circumstances, in the lungs
A) more carbon dioxide will diffuse out of the blood.
B) more carbon dioxide will diffuse into the blood.
C) less carbon dioxide will diffuse out of the blood.
D) less carbon dioxide will diffuse into the blood.
E) the amount of carbon dioxide diffusion will remain unchanged.
Answer: A
Learning Outcome: 3-5
Bloom's Taxonomy: Applying
116) Diffusion of a substance across the cell membrane may be influenced by all of the
following except
A) the availability of ATP.
B) the presence of membrane channels for the substance.
C) its charge of the substance.
D) its concentration gradient.
E) its lipid solubility.
Answer: A
Learning Outcome: 3-5
Bloom's Taxonomy: Understanding
117) There is a direct correlation between the potency of a general anesthetic such as ether and
its ability to
A) dissolve in water.
B) dissolve in lipids.
C) bind to proteins.
D) interact with carbohydrates.
E) bind to DNA.
Answer: B
Learning Outcome: 3-5
Bloom's Taxonomy: Understanding
32 Copyright © 2018 Pearson Education, Inc.
118) Water molecules and small ions enter a cell through
A) channels formed by integral membrane proteins.
B) peripheral proteins.
C) lipid channels.
D) peripheral carbohydrates.
E) defects in the lipid layer of the membrane.
Answer: A
Learning Outcome: 3-5
Bloom's Taxonomy: Remembering
119) Which of the following best describes osmosis?
A) active transport of water across the cell membrane
B) diffusion of water from a greater to a lesser water concentration
C) movement of water into a solute
D) diffusion of water from a greater to a lesser water concentration across a selectively
permeable membrane
E) random movement of water due to kinetic energy
Answer: D
Learning Outcome: 3-5
Bloom's Taxonomy: Understanding
120) Imagine a beaker divided down the center by a rigid membrane that is freely permeable to
water but impermeable to glucose. Side 1 contains a 10 percent glucose solution and side 2
contains the same volume of pure water. At equilibrium, what will be the situation?
A) Water will continue to move from side 1 to side 2.
B) Water will continue to move from side 2 to side 1.
C) The volume of liquid will be greater in side 1.
D) The volume of liquid will be greater in side 2.
E) The volume of liquid remain equal on both sides.
Answer: C
Learning Outcome: 3-5
Bloom's Taxonomy: Applying
121) A blood cell undergoes crenation when it is placed in a(n) ________ solution.
A) isotonic
B) hypertonic
C) hypotonic
D) merotonic
E) homotonic
Answer: B
Learning Outcome: 3-5
Bloom's Taxonomy: Understanding
33 Copyright © 2018 Pearson Education, Inc.
122) Hemolysis may occur when a blood cell is placed into a(n) ________ solution.
A) isotonic
B) hypertonic
C) hypotonic
D) merotonic
E) homotonic
Answer: C
Learning Outcome: 3-5
Bloom's Taxonomy: Understanding
123) If the amount of chloride ion in blood plasma increases, which of the following would
initially occur?
A) The blood osmotic pressure will increase.
B) The blood osmotic pressure will decrease.
C) The blood osmotic pressure will stay the same.
D) The blood hydrostatic pressure will increase.
E) The blood hydrostatic pressure will decrease.
Answer: A
Learning Outcome: 3-5
Bloom's Taxonomy: Understanding
124) If the concentration of sodium chloride in the interstitial fluid surrounding cells decreases
and the concentration of other solutes remains constant,
A) the cells will shrink.
B) the cells will swell.
C) the fluid outside of the cells will become isotonic.
D) the fluid outside of the cells will become hypertonic.
E) the cells will not change.
Answer: B
Learning Outcome: 3-5
Bloom's Taxonomy: Understanding
125) A solution that contains a lower osmotic pressure than the cytoplasm of a cell is called
A) merotonic.
B) hypertonic.
C) isotonic.
D) hypotonic.
E) homotonic.
Answer: D
Learning Outcome: 3-5
Bloom's Taxonomy: Remembering
34 Copyright © 2018 Pearson Education, Inc.
126) A patient suffers blood loss and is given IV fluids that contain an impermeable
carbohydrate called dextran, which serves to ________ leading to an increase in blood volume.
A) provide nutrition
B) increase the osmolarity of the blood
C) increase the oxygen-carrying capacity of the blood
D) decrease the osmolarity of the blood
E) reduce blood clotting
Answer: B
Learning Outcome: 3-5
Bloom's Taxonomy: Applying
127) In ________, one substance is transported into the cell and another is transported out.
A) cotransport
B) ditransport
C) countertransport
D) protransport
E) throughtransport
Answer: C
Learning Outcome: 3-6
Bloom's Taxonomy: Remembering
128) Assume that the import of a particular amino acid across the plasma membrane is observed
(1) to occur only down its concentration gradient and (2) to slow when a different but similar
amino acid is added to the extracellular fluid. The movement of the amino acid through the
membrane is most likely by
A) osmosis.
B) diffusion.
C) facilitated diffusion.
D) active transport.
E) pinocytosis.
Answer: C
Learning Outcome: 3-6
Bloom's Taxonomy: Applying
129) The process by which molecules such as glucose are moved into cells along their
concentration gradient with the help of membrane-bound carrier proteins is called
A) osmosis.
B) facilitated diffusion.
C) active transport.
D) endocytosis.
E) exocytosis.
Answer: B
Learning Outcome: 3-6
Bloom's Taxonomy: Remembering
35 Copyright © 2018 Pearson Education, Inc.
130) Facilitated diffusion differs from ordinary diffusion in that
A) facilitated diffusion consumes ATP.
B) facilitated diffusion moves molecules from an area of lower concentration to an area of higher
concentration.
C) the rate of facilitated diffusion is limited by the number of available carrier proteins.
D) facilitated diffusion never eliminates the concentration gradient.
E) facilitated diffusion does not rely on carrier proteins.
Answer: C
Learning Outcome: 3-6
Bloom's Taxonomy: Understanding
131) Membrane-bound proteins that use metabolic energy to move ions across the plasma
membrane are called ________ pumps.
A) channel
B) receptor
C) active
D) motor
E) ion
Answer: E
Learning Outcome: 3-6
Bloom's Taxonomy: Remembering
132) A process that requires cellular energy to move a substance against its concentration
gradient is called
A) active transport.
B) passive transport.
C) facilitated transport.
D) osmosis.
E) diffusion.
Answer: A
Learning Outcome: 3-6
Bloom's Taxonomy: Remembering
133) Secondary active transport
A) is not carried out by membrane proteins.
B) is not directly linked to the hydrolysis of ATP.
C) does not link the pumping of one substance to the concentration gradient of another.
D) does not require the cell to invest energy, either directly or indirectly.
E) cannot move a substance against its concentration gradient.
Answer: B
Learning Outcome: 3-6
Bloom's Taxonomy: Understanding
36 Copyright © 2018 Pearson Education, Inc.
134) An extracellular cation whose concentration gradient drives the secondary active transport
of many different solutes is
A) sodium.
B) calcium.
C) potassium.
D) chloride.
E) glucose.
Answer: A
Learning Outcome: 3-6
Bloom's Taxonomy: Understanding
135) In order to maintain cellular homeostasis, one abundant type of exchange pump ejects
________ ions from the cell and imports ________ ions.
A) potassium; calcium
B) sodium; calcium
C) potassium; sodium
D) sodium; potassium
E) calcium; sodium
Answer: D
Learning Outcome: 3-6
Bloom's Taxonomy: Remembering
136) All of the following membrane transport mechanisms are passive processes except
A) diffusion.
B) facilitated diffusion.
C) vesicular transport.
D) osmosis.
E) movement of water.
Answer: C
Learning Outcome: 3-6
Bloom's Taxonomy: Remembering
137) The intake of materials from the extracellular fluid using vesicles is called
A) osmosis.
B) exocytosis.
C) facilitated transport.
D) endocytosis.
E) an ion exchange pump.
Answer: D
Learning Outcome: 3-6
Bloom's Taxonomy: Remembering
37 Copyright © 2018 Pearson Education, Inc.
138) Endocytosis is a
A) method for transporting substances into the cell.
B) method for metabolizing within the cytosol.
C) form of anabolism.
D) viral infection.
E) method for packaging secretions.
Answer: A
Learning Outcome: 3-6
Bloom's Taxonomy: Understanding
139) Receptor-mediated endocytosis
A) is a type of secretion.
B) imports target molecules after they bind to membrane proteins.
C) does not require energy from the cell.
D) can only move a substance down its concentration gradient.
E) imports extracellular fluid, including all of its dissolved molecules.
Answer: B
Learning Outcome: 3-6
Bloom's Taxonomy: Understanding
140) A defense cell engulfing a bacterium illustrates
A) pinocytosis.
B) receptor-mediated exocytosis.
C) exocytosis.
D) phagocytosis.
E) receptor-mediated endocytosis.
Answer: D
Learning Outcome: 3-6
Bloom's Taxonomy: Understanding
141) The electric potential difference across the cell membrane is known as
A) the membrane potential.
B) the membrane difference.
C) the cellular potential.
D) the cellular difference.
E) the plasmalemma potential.
Answer: A
Learning Outcome: 3-7
Bloom's Taxonomy: Remembering
38 Copyright © 2018 Pearson Education, Inc.
142) The membrane potential in an undisturbed cell is called its
A) quiet potential.
B) inactive state.
C) passive state.
D) resting membrane potential.
E) interphase.
Answer: D
Learning Outcome: 3-7
Bloom's Taxonomy: Remembering
143) In a series of measurements of resting membrane potentials, the following values were
recorded. Which one is likeliest to be an error?
A) -10 mV
B) -20 mV
C) -40 mV
D) -70 mV
E) +100 mV
Answer: E
Learning Outcome: 3-7
Bloom's Taxonomy: Understanding
144) The potential difference across the cell membrane is due to the unequal distribution of
________ across the membrane.
A) carbohydrate molecules
B) water molecules
C) cations and anions
D) acids and bases
E) phospholipids and proteins
Answer: C
Learning Outcome: 3-7
Bloom's Taxonomy: Understanding
145) Which of these substances could be driven across a membrane by the resting membrane
potential?
A) H2O
B) O2
C) glucose
D) Na+
E) CO2
Answer: D
Learning Outcome: 3-7
Bloom's Taxonomy: Applying
39 Copyright © 2018 Pearson Education, Inc.
146) The genetically programmed death of cells is called
A) differentiation.
B) replication.
C) apoptosis.
D) metastasis.
E) mitosis.
Answer: C
Learning Outcome: 3-8
Bloom's Taxonomy: Remembering
147) If a cell lacked the enzyme DNA polymerase, it could not
A) maintain the integrity of the nuclear envelope.
B) form complementary strands of DNA during replication.
C) link segments of DNA together.
D) form spindle fibers.
E) form a new nuclear membrane during telophase.
Answer: B
Learning Outcome: 3-8
Bloom's Taxonomy: Understanding
148) In DNA replication,
A) 23 copies are made of each chromosome.
B) one new copy is made of each chromosome, and the original chromosome remains intact.
C) two new copies are made of each chromosome, and the original chromosome is destroyed.
D) two copies are made of each chromosome, and each copy contains one of the DNA strands
from the original chromosome.
E) the chromosome is copied to RNA, which is then copied to DNA for a new chromosome.
Answer: D
Learning Outcome: 3-8
Bloom's Taxonomy: Understanding
149) When is DNA replicated?
A) interphase
B) anaphase
C) metaphase
D) telophase
E) interkinesis
Answer: A
Learning Outcome: 3-8
Bloom's Taxonomy: Understanding
40 Copyright © 2018 Pearson Education, Inc.
150) The stage in a cell's life cycle in which the cell performs its normal functions and prepares
for division is called
A) prophase.
B) metaphase.
C) interphase.
D) telophase.
E) anaphase.
Answer: C
Learning Outcome: 3-8
Bloom's Taxonomy: Remembering
151) The process of duplicating chromosomes prior to cell division is called
A) replication.
B) repetition.
C) recurrence.
D) remodeling.
E) reassembling.
Answer: A
Learning Outcome: 3-8
Bloom's Taxonomy: Remembering
152) A cell duplicates its chromosomes during the ________ phase.
A) Go
B) G1
C) G2
D) Gm
E) S
Answer: E
Learning Outcome: 3-8
Bloom's Taxonomy: Remembering
153) Before a cell divides, its DNA must be replicated to
A) provide a backup copy of DNA in case the original DNA is damaged during mitosis.
B) replace the DNA lost during transcription.
C) supply each new cell with a full set of the genetic material.
D) replace genetic instructions used by the original cell.
E) use as an energy source during cytokinesis.
Answer: C
Learning Outcome: 3-8
Bloom's Taxonomy: Understanding
41 Copyright © 2018 Pearson Education, Inc.
154) The proper distribution of a somatic cell's genetic material to two daughter cells is
accomplished by the process of
A) cytosis.
B) mitosis.
C) cytokinesis.
D) phoresis.
E) meiosis.
Answer: B
Learning Outcome: 3-8
Bloom's Taxonomy: Remembering
155) During mitosis, chromatids separate into daughter chromosomes at the start of
A) prophase.
B) metaphase.
C) interphase.
D) telophase.
E) anaphase.
Answer: E
Learning Outcome: 3-8
Bloom's Taxonomy: Remembering
156) During this phase of cell division, the chromosomes uncoil, the nuclear membrane forms,
and cytokinesis occurs.
A) anaphase
B) prophase
C) interphase
D) telophase
E) metaphase
Answer: D
Learning Outcome: 3-8
Bloom's Taxonomy: Remembering
157) During mitosis, two daughter cells form, each of which has
A) a different number of chromosomes than the original cell.
B) twice as many chromosomes as the original cell.
C) the same number of chromosomes as the original cell.
D) a lesser number of chromosomes than the original cell.
E) half as many chromosomes as the original cell.
Answer: C
Learning Outcome: 3-8
Bloom's Taxonomy: Understanding
42 Copyright © 2018 Pearson Education, Inc.
158) The correct order of phases in the cell cycle is
A) prophase, interphase, anaphase, metaphase, and telophase.
B) telophase, anaphase, metaphase, interphase, and prophase.
C) interphase, prophase, anaphase, metaphase, and telophase.
D) interphase, prophase, metaphase, anaphase, and telophase.
E) metaphase, anaphase, interphase, prophase, and telophase.
Answer: D
Learning Outcome: 3-8
Bloom's Taxonomy: Understanding
159) If an animal cell has 18 chromosomes and undergoes mitosis, how many chromosomes
would each daughter cell have?
A) 9
B) 36
C) 23
D) 18
E) It varies, but the total number in the two daughter cells will always add up to 18.
Answer: D
Learning Outcome: 3-8
Bloom's Taxonomy: Understanding
160) Which phase of the cell cycle has the biggest extremes in duration?
A) S phase
B) G0 phase
C) G1 phase
D) G2 phase
E) V phase
Answer: B
Learning Outcome: 3-8
Bloom's Taxonomy: Understanding
161) Generally, cells with a very brief interphase and lacking a G0 phase
A) are stem cells.
B) do not exhibit cytokinesis.
C) have brief life spans.
D) are reproductive cells.
E) lack the enzyme DNA polymerase.
Answer: A
Learning Outcome: 3-8
Bloom's Taxonomy: Understanding
43 Copyright © 2018 Pearson Education, Inc.
162) Special cells called ________ cells maintain tissues by unending cycles of cell division.
A) cytogenic
B) mother
C) stem
D) root
E) omnipotent
Answer: C
Learning Outcome: 3-8
Bloom's Taxonomy: Remembering
163) The physical process by which a single animal cell separates into two cells is called
A) cytosis.
B) mitosis.
C) cytokinesis.
D) phoresis.
E) meiosis.
Answer: C
Learning Outcome: 3-8
Bloom's Taxonomy: Remembering
164) During growth, a tissue increases in size by
A) increasing the size of its cells.
B) increasing the osmolarity of its tissue fluid to draw in water.
C) increasing its rate of cell division.
D) dilating blood vessels to increase its blood supply.
E) recruiting cells from surrounding tissues.
Answer: C
Learning Outcome: 3-9
Bloom's Taxonomy: Understanding
165) A chemical from outside a cell that promotes cell division is called a
A) nutrient.
B) promoter.
C) mutagen.
D) telomere.
E) growth factor.
Answer: E
Learning Outcome: 3-9
Bloom's Taxonomy: Remembering
44 Copyright © 2018 Pearson Education, Inc.
166) Cyclin, a protein that becomes more abundant as the cell cycle proceeds,
A) delays cytokinesis.
B) activates repressor genes.
C) triggers DNA replication.
D) damages telomeres.
E) takes part in triggering mitosis.
Answer: E
Learning Outcome: 3-9
Bloom's Taxonomy: Understanding
167) When telomeres get too short after repeated cell divisions,
A) the cell dies.
B) the cell becomes cancerous.
C) the cell stops dividing.
D) the chromosomes uncoil.
E) the cell divides more frequently.
Answer: C
Learning Outcome: 3-9
Bloom's Taxonomy: Understanding
168) An alternate term for tumor is
A) neoplasm.
B) cytoplasm.
C) benign malignancy.
D) primary metastasis.
E) nucleoplasm.
Answer: A
Learning Outcome: 3-10
Bloom's Taxonomy: Remembering
169) Cancer cells
A) are indistinguishable from normal body cells.
B) have a slow mitotic rate.
C) may exhibit metastasis.
D) do not form neoplasms.
E) generally form benign tumors.
Answer: C
Learning Outcome: 3-10
Bloom's Taxonomy: Understanding
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170) A(n) ________ is a mutated regulatory gene that causes cancer.
A) neogene
B) plasmogene
C) toxogene
D) oncogene
E) monogene
Answer: D
Learning Outcome: 3-10
Bloom's Taxonomy: Remembering
171) ________, which is usually inactive in adult cells, is active in 90% of cancer cells.
A) Phagocytosis
B) Apoptosis
C) The p53 gene
D) Telomerase
E) DNA polymerase
Answer: D
Learning Outcome: 3-10
Bloom's Taxonomy: Understanding
172) The process by which cells become specialized is called
A) determination.
B) cytokinesis.
C) mutation.
D) differentiation.
E) distinction.
Answer: D
Learning Outcome: 3-11
Bloom's Taxonomy: Remembering
173) Different cell types in the body
A) produce exactly the same proteins.
B) have different genes.
C) are identical except for their superficial appearance.
D) have the same genes, but different sets of genes are inactivated.
E) have the ability to take on the characteristics of each other or any cell in the body.
Answer: D
Learning Outcome: 3-11
Bloom's Taxonomy: Understanding
46 Copyright © 2018 Pearson Education, Inc.
174) Embryonic stem cells might be used to replace neurons lost in Parkinson's Disease because
A) they are readily available.
B) they divide quickly.
C) they are young and vigorous.
D) they have not yet differentiated.
E) they are taken from the brain of the embryo.
Answer: D
Learning Outcome: 3-11
Bloom's Taxonomy: Understanding
In-Text Figure Based Questions
1) What are the three different components that make up the cytoskeleton in all body cells?
(Figure 3-3)
A) thick filaments, thin filaments, intermediate filaments
B) microfilaments, microvilli, villi
C) microfilaments, intermediate filaments, microtubules
D) thick filaments, thin filaments, microvilli
E) microtubules, macrotubules, tubules
Answer: C
Learning Outcome: 3-2
Bloom's Taxonomy: Remembering
2) What are the two reactants shown here that are necessary for energy production? What are the
three products shown here as a result of this reaction? (Figure 3-9)
A) oxygen and ATP; carbon dioxide, pyruvate, and water
B) oxygen and carbon dioxide; pyruvate, carbon dioxide, and water
C) water and pyruvate; oxygen, carbon dioxide, and ATP
D) oxygen and pyruvate; carbon dioxide, ATP, and water
E) carbon dioxide and pyruvate; oxygen, ATP, and water
Answer: D
Learning Outcome: 3-2
Bloom's Taxonomy: Remembering
3) How is DNA organized in the nucleus when the cell is prepared for division? How is DNA
organized in the nucleus when the cell is not dividing? (Figure 3-11)
A) tightly coiled as chromosomes; loosely coiled as chromatin
B) tightly coiled as chromatin; loosely coiled as chromosomes
C) loosely coiled as chromosomes; tightly coiled as chromatin
D) loosely coiled as chromatin; tightly coiled as chromosomes
E) loosely coiled as chromosomes; loosely coiled as chromatin
Answer: A
Learning Outcome: 3-3
Bloom's Taxonomy: Remembering
47 Copyright © 2018 Pearson Education, Inc.
4) How do small water-soluble molecules and ions diffuse across the plasma membrane? How do
lipid-soluble molecules diffuse across the plasma membrane? (Figure 3-15)
A) diffuse by osmosis; diffuse by carrier-mediated transport
B) diffuse by endocytosis; diffuse by pinocytosis
C) diffuse by carrier-mediated transport; diffuse by passive transport
D) diffuse directly through the plasma membrane; diffuse through membrane channels
E) diffuse through membrane channels; diffuse directly through the plasma membrane
Answer: E
Learning Outcome: 3-5
Bloom's Taxonomy: Remembering
5) Describe the concentration of the intracellular fluid relative to the extracellular fluid in parts b
and c. (Figure 3-17)
A) hypotonic to the extracellular fluid; hypertonic to the extracellular fluid
B) hypertonic to the extracellular fluid; hypotonic to the extracellular fluid
C) isotonic to the extracellular fluid; hypertonic to the extracellular fluid
D) isotonic to the extracellular fluid; hypotonic to the extracellular fluid
E) hypertonic to the extracellular fluid; isotonic to the extracellular fluid
Answer: B
Learning Outcome: 3-5
Bloom's Taxonomy: Remembering
6) In the facilitated diffusion of glucose, what determines the direction in which glucose
molecules will be transported? (Figure 3-18)
A) the amount of ATP available inside the cell versus outside the cell
B) the amount of sodium available to bind inside the cell versus outside the cell
C) the concentration gradient
D) the voltage of the membrane
E) the tonicity of the cell
Answer: C
Learning Outcome: 3-6
Bloom's Taxonomy: Understanding
7) What provides the energy for the sodium-potassium exchange pump? (Figure 3-19)
A) breaking the high energy bond of ADP
B) the concentration gradient of sodium
C) the concentration gradient of potassium
D) breaking the high energy bond of ATP
E) the voltage of the cell
Answer: D
Learning Outcome: 3-6
Bloom's Taxonomy: Remembering
48 Copyright © 2018 Pearson Education, Inc.
Essay Questions
1) Describe the ways that proteins of the plasma membrane allow a cell to control its internal
environment or interact with its external environment.
Answer: Carrier proteins and channels help control the cell's internal environment by allowing
specific materials to enter the cell. Anchoring proteins connect the cell's cytoskeleton to
extracellular proteins or to other cells. Recognition proteins allow immune cells to identify the
cell. Receptor proteins allow the cell to respond to external signals such as hormones. Finally,
enzymes can carry out chemical reactions inside or outside the cell, depending on which face of
the membrane they are attached to.
Learning Outcome: 3-1
Bloom's Taxonomy: Understanding
2) Which organelles are involved in membrane flow? Trace the route of a single integral
membrane protein from formation to incorporation into the plasma membrane.
Answer: All membranous organelles are involved in membrane flow. Those most directly
associated are the ER, Golgi apparatus, secretory vesicles, and plasma membrane. A membrane
protein would be synthesized in the RER, then flow through the cisternae to a transport vesicle.
There the protein will be moved to the forming face of the Golgi apparatus, where it will slowly
travel upward toward the maturing face, usually becoming modified along the way. Once
reaching the maturing face of the Golgi apparatus, the protein would be embedded in the
membrane of a secretory vesicle and transported to the plasma membrane. There the vesicle will
fuse with the membrane, inserting the protein in the cell membrane.
Learning Outcome: 3-2
Bloom's Taxonomy: Applying
3) What organelles would be enhanced in a cell that produces digestive enzymes and secretes
them into the intestine? Why?
Answer: Digestive enzymes are proteins, and they are produced at a high rate while a meal is
being digested. Organelles that would be enhanced include the nucleus, which would have larger
or more numerous nucleoli for making ribosomes; a larger number of ribosomes for making
proteins; increased rough ER, where proteins to be secreted are made; more numerous or larger
Golgi apparatus, where proteins are packaged for secretion; and more secretory vesicles to carry
the enzymes to the surface of the cell.
Learning Outcome: 3-2
Bloom's Taxonomy: Applying
4) Differentiate between transcription and translation.
Answer: In transcription, RNA polymerase uses the nucleotide sequence on DNA to construct a
complementary strand of mRNA. In translation, ribosomes use information carried by the mRNA
strand and tRNA to synthesize the corresponding polypeptide.
Learning Outcome: 3-4
Bloom's Taxonomy: Understanding
49 Copyright © 2018 Pearson Education, Inc.
5) When a person receives intravenous fluids to help build up blood volume, why is it important
for the fluid to be isotonic?
Answer: Intravenous fluids must be isotonic to prevent the cells from losing or gaining water. If
the solution was hypertonic, the cells of the body would lose water, shrink, and possibly be
harmed. On the other hand, the introduction of hypotonic fluid would cause the cells to swell and
tissues to rupture.
Learning Outcome: 3-5
Bloom's Taxonomy: Applying
6) Define osmosis and tell in what direction it occurs.
Answer: Osmosis is the transfer of water across a semipermeable membrane due to a difference
in concentration of impermeant solutes. Water moves from lower to higher solute concentration
(or from higher to lower water concentration, or from lower to higher osmolarity, or from lower
to higher tonicity).
Learning Outcome: 3-5
Bloom's Taxonomy: Understanding
7) During kidney dialysis, a person's blood is passed through a bath that contains several ions
and molecules. The blood is separated from the dialysis fluid by a membrane that allows water,
small ions, and small molecules to pass, but does not allow large proteins or blood cells to pass.
What should the composition of dialysis fluid be for it to remove urea (a small molecule without
changing the blood volume (removing water from the blood)?
Answer: For the dialysis fluid to remove urea without removing water, it should not contain
urea. Because urea is a small molecule, it will diffuse through the dialysis membrane from an
area of high concentration (the blood to an area of low concentration (the dialysis fluid). To
prevent an associated osmotic water movement, the dialysis fluid should have an osmotic
concentration similar to that of blood plasma, but with higher concentrations of solutes such as
bicarbonate ions or glucose. As urea diffuses into the dialysis fluid, glucose and bicarbonate
diffuse into the blood; as a result, the solute concentrations remain in balance and no osmotic
water movement occurs.
Learning Outcome: 3-5
Bloom's Taxonomy: Applying
8) A) What are the similarities between facilitated diffusion and active transport? B) What are
the differences?
Answer: A) Both processes use carrier proteins and exhibit saturation. B) Facilitated diffusion is
driven by a concentration gradient, does not consume ATP, and so is "passive," whereas active
transport is active, consumes ATP, and moves a substance up its concentration gradient.
Learning Outcome: 3-6
Bloom's Taxonomy: Understanding
50 Copyright © 2018 Pearson Education, Inc.
9) Tell how a carcinogen can cause cancer, and describe the progression of cancer.
Answer: Some carcinogens directly cause rapid cell division and others are mutagens that may
mutate a gene that regulates cell growth, differentiation, or division. Cancer begins with
increased cell division to produce a cluster of cells called a tumor or neoplasm. These cells
change their appearance, lose their response to certain inhibitory signals, and may acquire other
mutations. Malignancy occurs as cells from the tumor invade surrounding tissues. Metastasis
occurs when these cells enter the circulatory system and start tumors in distant regions of the
body. Angiogenesis is the growth of blood vessels into the region of the tumor. Tumors can
disrupt normal function by failing to carry out their regular functions, physically interfering with
normal tissue, outcompeting normal tissues for nutrients, or overproducing their normal
products, such as hormones.
Learning Outcome: 3-10
Bloom's Taxonomy: Understanding