G1

S

G2

mitosis

Cytokinesis:

new protein and organelles made

DNA replicates

Proteins needed for cell division made

Nucleus divides

cytoplasm divides

The cell cycle

growth

Subject to copyright clearance a suitable image showing mitosis could be inserted here.

e.g. one similar to that found at:

http://www.microscopy-uk.org.uk/mag/imgaug99/whole.jpg

Cell at interphase•Protein synthesis

•Organelle synthesis•DNA replication

Subject to copyright clearance a suitable image showing interphase could be inserted here.

e.g. one similar to that found at:

http://www.fed.cuhk.edu.hk/~johnson/photomicrographs/mitosis/animal/animal_interphase.htm

A single chromosome at the beginning of mitosis

Has two chromatids

as the DNA replicates during interphase before mitosis

centromere

Early prophase

DNA coils and condensesChromosomes take up stain

centrioles

nucleolus

Centrioles move apart

Nucleolus fades

Chromosomes continue to condense

Nuclear membrane breaks down

prophase

Nucleolus disappears Chromosomes continue to condense

metaphase

Nuclear membrane broken down

Chromosomes aligned on the equator

Each chromosome attached to spindle fibre by the centromere

Centromeres divide and chromatids pulled apart

Anaphase

Anaphase

anaphase

AnaphaseSister chromatids are pulled to opposite poles of the cell

Subject to copyright clearance a suitable set of images showing the various stages of mitosis could be inserted here.