1
737 former could be released at some date earlier than sixteen weeks—the time one little girl, whom I saw at Sbanmore, was occupied in her peeling. Strapping the feet with a plaster containing salicylic acid, or, as Dr. Jamieson suggests, resorcin, might help. Its known eflects on corns and warts look promising. I must apologise for occupying your space, but the hope of inciting others with more valuable experience to communicate their views must be my excuse. I am, Sirs, yours truly, , H. HOWARD MURPHY, M.D. GASTRO-ENTEROSTOMY FOLLOWED BY RECURRENCE OF SYMPTOMS. To the Editors of THE LANCET. SIRS,—I have read with much interest the report of I Mr. F. C. Larkin’s case of gastro-enterostomy, followed later by recurrence of symptoms for which jejunostomy was per- formed. In the remarks Mr. Larkin says : "There can be no doubt that the recurrence of symptoms was due to ’ closure of the preternatural orifice. This closure might have occurred from one of two causes: (1) Extension of the malignant growth around and over the orifice; (2) closure by cicatricial contraction." After carefully reading the case I am inclined to think that there may be a third cause for the recurrence of symptoms, which, I believe, will be "found to ba the correct one-viz , constriction of the jejunum at the aperture in the transverse meeo-colon or great omentum, through which he intestine was drawn. That the extension of the malignant growth over the orifice may be found to be the cause is possible, but I do not think so probable as that the intestine was constricted or kinked. The question as to the closure of the opening made between the stomach and jejunum in gastro-enterostomy is a most serious and important one. The only authentic case ,of closure of the opening by cicatricial contraction that has been reported, so far as I am aware, is Mr. Stansfield’s. The case reported by Mr. Kilner Clarke, in which the symptoms returned-and he inferred that the opening had closed-he unfortunately was unable to confirm, as a post-mortem examination of the patient was not permitted. Personally I have performed gastro enterostomy five times, three successfully ; and once I have performed pylorectomy combined with gastro-enterostomy successfully (the report - of this case will, with your permission, appear in your columns shortly), in none of these did any cicatricial contraction occur. Although one lived nine months after the operation, the two others are alive now, one eighteen months and the other eleven months since the operation of gastro-enterostomy. These patients take ordinary diet. The case of combined pylorec. tomy with gastro enterostomy has now been operated on seven weeks, and is being fed upon fish, minced meat, beef- tea, eggs, and milk. She suffers no pain or discomfort after taking food. Experimentally I have performed a large number of operations for gastro-enterostomy, ileo-ileostomy, .and ileo-colostomy ; in no case have I ever found any cicatricial contraction. I therefore think we must look further than the gastro-jejunal opening for the cause of the obstruction in Mr. Larkin’s case, and consider it will be found to be the result of one of the causes I have mentioned. One word as to the method employed by Mr. Larkin in ,performing so successfully the operation he has reported. I have advocated and practised a method of uniting the jejunum to the posterior wall of the stomach through an opening in the transverse meso-colon ; I have also made ’experiments in the same direction, but for reasons that ’would occupy too much of your space in this letter I have abandoned it in favour of the ordinary method of fixing the intestine to the anterior wall of the stomach. I consider in those cases in which the disease in the stomach is so exten- sive that it is difficult to find a suitable piece of healthy stomach to affix the intestine to, that jejunostomy per- formed.in the way I have suggested, and which Mr. Larkin , has so successfully performed in his case, is the only opera- tion that is at all likely to give the patient relief. I am, Sirs, yours very faithfully, FREDK. BOWREMAN JESSETT. CHLOROFORM SYNCOPE. To the Editors of THE LANCET. SIRS,-For those who do not require further proofs that :hloroform inhalation may cause syncope, cases like that ’f Dr. Rice in THE LANCET of Sept. 19th have an nterest of a different kind. This springs from our lesire to find out from such reports the modus operandi )f the anaesthetic in producing this dreadful result, and for this purpose a non-fatal case is as important as a fatal one. The report in this case, however, shows bhat there may be a radical difference of opinion as to the actual facts, which ought to be attended to and recorded. The report says not a word as to the moment when the administration was stopped. Was this done when the head was lowered and after the pupils had dilated, or was it done when the first observations on the pulse were made? If the latter, how much time elapsed while the several observations on the pulse were being made and before the pupil dilated ? Apart from any theory as to the cause of syncope, it is an undeniable fact that it has often occurred some time after the inhalation has been stopped ; and it is of the utmost importance to determine when such is the case, and when, if ever, the catastrophe may take place during the administration of a continuous atmosphere. It seems to follow as a necessary consequence from the terrible power of chloroform to cause syncope that the pulse must be watched. I beg to submit that this in- ference may be erroneous, and I utterly dissent from it. I believe that syncope is invariably the result of reaction from stopping the inhalation too soon, so that the chloroformist has only to go on with confidence, regardless of the pulse, the observation of which, indeed, may even give rise to a false alarm and drive him into the very danger he seeks to avoid. We may also ask if there were no interrup- tions to the administration in the above case before the dangerous symptoms set in ? It is surely remarkable that three drachms of chloroform were expended without anaesthetising the patient, and it is deserving of notice that the same thing is recorded in the last death from methylene and Junker’s inhaler, and in which it is expressly stated that the inhaler was removed from time to time. We are told that anaesthesia may be maintained for an hour, and longer, with six drachms of methylene given by this inhaler, and that one drachm of chloroform is sufficient for an operation lasting ten minutes. If so, it would seem probable that breaks were allowed in the inhalation in the above case; and at least I would beg to draw attention to the point as one which I believe to be of vital importance. I am. Sirs. vours &c.. ROBERT KIRK, M.D. CAP MARTIN: A NEW HEALTH STATION ON THE RIVIERA. To the Editors of THE LANCET. SIRS,-At this time of the year, when so many people are forming plans for the winter, I should like to draw the attention of the profession to Cap Martin. As its name implies it is a small cape, running out into the Mediterranean Sea between Mentone on the east and Monte Carlo on the west. It faces full south, and is far enough removed from the range of Maritime Alps behind to avoid those sweeping draughts which come down the valleys, and which are such serious drawbacks to Mentone and Nice. The whole estate is covered with pines, under which is a rich growth of underwood, consisting chiefly of myrtle and rosemary, making the air most fragrant and pleasant. When the estate is fully developed it will somewhat resemble the East Cliff at Bournemouth, only it will be set off with brilliant blues and greens instead of the almost uniform depressing grey of Bournemouth in the winter. For cases requiring a still atmosphere Cap Martin will be very suit- able, as under these trees even duringaalf a gale the move- ment felt in the air is so slight that phthisical patients with a hæmorrhagic tendency and cardiac cases are able to go out and get their exercise in safety. Another important feature in Cap Martin is that it is level, thus differing from most other Mediterranean health stations. The history of the place is this. About two or three years ago a Scotchman, Mr. Colvin White, bought the whole estate of about 200 acres. It was then a dense wood, used

GASTRO-ENTEROSTOMY FOLLOWED BY RECURRENCE OF SYMPTOMS

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737

former could be released at some date earlier than sixteenweeks—the time one little girl, whom I saw at Sbanmore,was occupied in her peeling. Strapping the feet with aplaster containing salicylic acid, or, as Dr. Jamieson

suggests, resorcin, might help. Its known eflects on cornsand warts look promising. I must apologise for occupyingyour space, but the hope of inciting others with morevaluable experience to communicate their views must be myexcuse. I am, Sirs, yours truly, ,

H. HOWARD MURPHY, M.D.

GASTRO-ENTEROSTOMY FOLLOWED BYRECURRENCE OF SYMPTOMS.

To the Editors of THE LANCET.

SIRS,—I have read with much interest the report of IMr. F. C. Larkin’s case of gastro-enterostomy, followed later by recurrence of symptoms for which jejunostomy was per- formed. In the remarks Mr. Larkin says : "There can be no doubt that the recurrence of symptoms was due to ’closure of the preternatural orifice. This closure mighthave occurred from one of two causes: (1) Extension of themalignant growth around and over the orifice; (2) closureby cicatricial contraction." After carefully reading thecase I am inclined to think that there may be a third causefor the recurrence of symptoms, which, I believe, will be"found to ba the correct one-viz , constriction of the jejunumat the aperture in the transverse meeo-colon or greatomentum, through which he intestine was drawn. Thatthe extension of the malignant growth over the orificemay be found to be the cause is possible, but I do notthink so probable as that the intestine was constricted orkinked.The question as to the closure of the opening made between

the stomach and jejunum in gastro-enterostomy is a mostserious and important one. The only authentic case

,of closure of the opening by cicatricial contraction that hasbeen reported, so far as I am aware, is Mr. Stansfield’s.The case reported by Mr. Kilner Clarke, in which thesymptoms returned-and he inferred that the opening hadclosed-he unfortunately was unable to confirm, as a

post-mortem examination of the patient was not permitted.Personally I have performed gastro enterostomy five times,three successfully ; and once I have performed pylorectomycombined with gastro-enterostomy successfully (the report- of this case will, with your permission, appear in yourcolumns shortly), in none of these did any cicatricialcontraction occur. Although one lived nine monthsafter the operation, the two others are alive now,one eighteen months and the other eleven monthssince the operation of gastro-enterostomy. These patientstake ordinary diet. The case of combined pylorec.tomy with gastro enterostomy has now been operated on seven weeks, and is being fed upon fish, minced meat, beef-tea, eggs, and milk. She suffers no pain or discomfort aftertaking food. Experimentally I have performed a largenumber of operations for gastro-enterostomy, ileo-ileostomy,.and ileo-colostomy ; in no case have I ever found anycicatricial contraction. I therefore think we must lookfurther than the gastro-jejunal opening for the cause of theobstruction in Mr. Larkin’s case, and consider it will befound to be the result of one of the causes I havementioned.One word as to the method employed by Mr. Larkin in

,performing so successfully the operation he has reported. Ihave advocated and practised a method of uniting thejejunum to the posterior wall of the stomach through anopening in the transverse meso-colon ; I have also made’experiments in the same direction, but for reasons that’would occupy too much of your space in this letter I haveabandoned it in favour of the ordinary method of fixing theintestine to the anterior wall of the stomach. I consider inthose cases in which the disease in the stomach is so exten-sive that it is difficult to find a suitable piece of healthystomach to affix the intestine to, that jejunostomy per-formed.in the way I have suggested, and which Mr. Larkin

, has so successfully performed in his case, is the only opera-tion that is at all likely to give the patient relief.

I am, Sirs, yours very faithfully,FREDK. BOWREMAN JESSETT.

CHLOROFORM SYNCOPE.To the Editors of THE LANCET.

SIRS,-For those who do not require further proofs that:hloroform inhalation may cause syncope, cases like that’f Dr. Rice in THE LANCET of Sept. 19th have an

nterest of a different kind. This springs from our

lesire to find out from such reports the modus operandi)f the anaesthetic in producing this dreadful result,and for this purpose a non-fatal case is as importantas a fatal one. The report in this case, however, showsbhat there may be a radical difference of opinion as to theactual facts, which ought to be attended to and recorded.The report says not a word as to the moment when theadministration was stopped. Was this done when thehead was lowered and after the pupils had dilated,or was it done when the first observations on thepulse were made? If the latter, how much time elapsedwhile the several observations on the pulse were being madeand before the pupil dilated ? Apart from any theory as tothe cause of syncope, it is an undeniable fact that it hasoften occurred some time after the inhalation has beenstopped ; and it is of the utmost importance to determinewhen such is the case, and when, if ever, the catastrophemay take place during the administration of a continuousatmosphere. It seems to follow as a necessary consequencefrom the terrible power of chloroform to cause syncope thatthe pulse must be watched. I beg to submit that this in-ference may be erroneous, and I utterly dissent from it. Ibelieve that syncope is invariably the result of reaction fromstopping the inhalation too soon, so that the chloroformisthas only to go on with confidence, regardless of the pulse,the observation of which, indeed, may even give rise to afalse alarm and drive him into the very danger he seeks toavoid. We may also ask if there were no interrup-tions to the administration in the above case beforethe dangerous symptoms set in ? It is surely remarkablethat three drachms of chloroform were expended withoutanaesthetising the patient, and it is deserving of notice thatthe same thing is recorded in the last death from methyleneand Junker’s inhaler, and in which it is expressly statedthat the inhaler was removed from time to time. We aretold that anaesthesia may be maintained for an hour, andlonger, with six drachms of methylene given by this inhaler,and that one drachm of chloroform is sufficient for anoperation lasting ten minutes. If so, it would seem probablethat breaks were allowed in the inhalation in the abovecase; and at least I would beg to draw attention to thepoint as one which I believe to be of vital importance.

I am. Sirs. vours &c..ROBERT KIRK, M.D.

CAP MARTIN: A NEW HEALTH STATIONON THE RIVIERA.

To the Editors of THE LANCET.SIRS,-At this time of the year, when so many people

are forming plans for the winter, I should like to draw theattention of the profession to Cap Martin. As its nameimplies it is a small cape, running out into the MediterraneanSea between Mentone on the east and Monte Carlo on thewest. It faces full south, and is far enough removed fromthe range of Maritime Alps behind to avoid those sweepingdraughts which come down the valleys, and which are suchserious drawbacks to Mentone and Nice. The whole estateis covered with pines, under which is a rich growth ofunderwood, consisting chiefly of myrtle and rosemary,making the air most fragrant and pleasant. When theestate is fully developed it will somewhat resemble theEast Cliff at Bournemouth, only it will be set off withbrilliant blues and greens instead of the almost uniformdepressing grey of Bournemouth in the winter. For casesrequiring a still atmosphere Cap Martin will be very suit-able, as under these trees even duringaalf a gale the move-ment felt in the air is so slight that phthisical patients witha hæmorrhagic tendency and cardiac cases are able to goout and get their exercise in safety. Another importantfeature in Cap Martin is that it is level, thus differing frommost other Mediterranean health stations.The history of the place is this. About two or three

years ago a Scotchman, Mr. Colvin White, bought the wholeestate of about 200 acres. It was then a dense wood, used