1
111 which will enable us to split up and analyse more complex pictures. Such common dreams as anxiety about passing an examination, which in reality we passed 30 to 40 years ago, or of forgetting an appoint- ment, or of leaving things behind, may likewise have a simple, though in their case a psychical, basis. The flying dreams seem to me to have their cause in a partial awareness of respiration. The flight is usually up and down, and not in the same horizontal plane. Again, it is difficult sometimes to move a limb when just beginning to be aroused from sleep, and that might be the basis of the dream with cloying feet. A friend tells me that whenever he goes to sleep with a feeling of nausea he is likely to dream of being on a ship at sea or to see waves passing rhythmically before his eyes. For this the explana- tion seems simple, though not romantic. But enough of these reflections, or the writer will be out of his rather shallow depth. * * * A South African experience compelled me to share a room with a bricklayer, and a more perfect bedroom companion I have never met. There was no egotistic scramble for the minor comforts of life, but the self sacrifice and courtesy of a Spanish Grandee, which soon became mutual. Pondering why this man, whose education had been elementary, was such a pleasant companion, while others we encounter, who may have been to Eton and Cambridge, are not always so pleasant, the answer seemed to be that this one had been trained in the best school of all- adversity-an advantage not shared by everyone. Shakespeare and others have told us of the uses of adversity, and most doctors could tell how they have seen characters tempered and improved by adversity and suffering. Not all natures will react favourably to difficulties but fortunately the great majority do so react. * * * The value of quotation in speech and writing has much diminished. The Victorians enriched their heavy orations with long Latin or Greek quotations which would bore hearers to-day, and indeed did little more, even then, than advertise the classical erudition of the speaker. To-day many speakers still interpolate poetry or prose quotations, suggesting again the erudition of the speaker, but often without clarifying the subject under consideration. In the past I have made another use of quotation ; if a trite aphorism or bright idea came to my mind I would produce it as a quotation from some distant author. It seemed that an audience paid more attention to my ideas if attributed to Dante or Milton, of whose pages I am, in fact, profoundly ignorant. To-day, with the passage of years, I rarely use quotations, but endeavour to express myself clearly and give no one else credit for my ideas. If such a step belittles my learning it were just as well belittled. Such ideas have no doubt occurred to others in the distant past, but there is no harm in restating them to-day. CORRESPONDENCE HÆMORRHAGE IN GASTRIC AND DUODENAL ULCER To the Editor of THE LANCET SIR,-In your last issue Hurst and Ryle state that the danger of haemorrhage from peptic ulcers has been grossly exaggerated in papers recently appearing in British journals. I cannot help feeling that this statement calls for examination. Hurst, from figures collected by Babey/ says that the mortality-rate for cases of peptic ulcer admitted under his care to Guy’s Hospital on account of recent haemorrhage, and in which death was directly attributable to haemorrhage, is 4’8 per cent. Compared with this Babey sets out a table "showing mortality rates of haemorrhage from ulcer given by various authors " some of which are over 20 per cent. This table is misleading because no mention is made of the different criteria adopted by the various authors when compil- ing their statistics. For example, Conybeare 2 arguing from the number of post-mortems of all cases admitted to Guy’s Hospital for haematemesis or melaena from 1911 to 1920 (inclusive) showed a mortality of about 4-3 per cent. Burger and Hartfall3 3 found the mortality from severe haematemesis at the same hospital from 1921 to 1930 (inclusive) to be 22-6 per cent. The last figure includes deaths from complica- tions and there seems no useful reason why they should be omitted whether from cardiac failure or even following surgical intervention. It seems quite clear therefore from a study of the available statistics that, omitting cases of melsena, the death-rate in hospitals from severe hsematemesis has not been 1 Babey, A. M., and Hurst, A. F. (1936) Guy’s Hosp. Rep. 86, 129. 2 Conybeare, J. J., Quoted by Hurst, A. F. (1923-24) Proc. R. Soc. Med. 17, 20 ; (1924) Lancet, 1, 1095. 3 Burger, G., and Hartfall, J. (1934) Guy’s Hosp. Rep. 84, 167. exaggerated and is still disturbingly high. Another evident fact not stressed by Hurst and Ryle is that repeated haemorrhage is the most serious prognostic sign. A single bleeding, however severe, is rarely fatal. The mortality in Hurst’s cases at Guy’s which had further gross bleeding in the wards was 27 per cent. With regard to blood transfusion, another important point dealt with by these authors, we found when examining a series of cases (Cullinan and Price 4) and by subsequent experience that when it is considered necessary to transfuse because of severe anaemia it is wise to wait until several hours after the gross bleeding has ceased. Not only does trans- fusion of itself fail to arrest haemorrhage but it may even cause further bleeding if performed immediately. To this rule there is one exception : in cases with severe anaemia when gradual bleeding has been going on for several days transfusion may be a life- saving measure. We also thought that the giving of enemata before the sixth day after a severe haematemesis carried a risk of further bleeding. I do not wish to imply in any way that because the mortality in hospitals from severe haematemesis is high that this is any reason for more frequent surgical intervention. For the reasons Hurst and Ryle so clearly state immediate operation is very seldom desirable. Their plea for the avoidance, whenever possible, of disturbing therapeusis and for treatment with quiet and rest in the widest sense is unassailable. Courage lies not in action but in confident inaction. I am, Sir, yours faithfully, EDWARD R. CULLINAN. 4 Cullinan, E. R., and Price, R. K. (1932) St. Bart’s Hosp. Rep. 65, 185.

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Page 1: HÆMORRHAGE IN GASTRIC AND DUODENAL ULCER

111

which will enable us to split up and analyse morecomplex pictures. Such common dreams as anxietyabout passing an examination, which in reality wepassed 30 to 40 years ago, or of forgetting an appoint-ment, or of leaving things behind, may likewise havea simple, though in their case a psychical, basis.The flying dreams seem to me to have their cause

in a partial awareness of respiration. The flight is

usually up and down, and not in the same horizontalplane. Again, it is difficult sometimes to move alimb when just beginning to be aroused from sleep,and that might be the basis of the dream with cloyingfeet. A friend tells me that whenever he goes tosleep with a feeling of nausea he is likely to dream ofbeing on a ship at sea or to see waves passingrhythmically before his eyes. For this the explana-tion seems simple, though not romantic.But enough of these reflections, or the writer will

be out of his rather shallow depth.* * *

A South African experience compelled me to sharea room with a bricklayer, and a more perfect bedroomcompanion I have never met. There was no egotisticscramble for the minor comforts of life, but the selfsacrifice and courtesy of a Spanish Grandee, whichsoon became mutual. Pondering why this man,whose education had been elementary, was such apleasant companion, while others we encounter,who may have been to Eton and Cambridge, are notalways so pleasant, the answer seemed to be that

this one had been trained in the best school of all-adversity-an advantage not shared by everyone.Shakespeare and others have told us of the uses ofadversity, and most doctors could tell how they haveseen characters tempered and improved by adversityand suffering. Not all natures will react favourablyto difficulties but fortunately the great majority doso react.

* * *

The value of quotation in speech and writing hasmuch diminished. The Victorians enriched their

heavy orations with long Latin or Greek quotationswhich would bore hearers to-day, and indeed didlittle more, even then, than advertise the classicalerudition of the speaker. To-day many speakersstill interpolate poetry or prose quotations, suggestingagain the erudition of the speaker, but often withoutclarifying the subject under consideration. In thepast I have made another use of quotation ; if atrite aphorism or bright idea came to my mindI would produce it as a quotation from some distantauthor. It seemed that an audience paid moreattention to my ideas if attributed to Dante or

Milton, of whose pages I am, in fact, profoundlyignorant. To-day, with the passage of years, I

rarely use quotations, but endeavour to expressmyself clearly and give no one else credit for myideas. If such a step belittles my learning it werejust as well belittled. Such ideas have no doubtoccurred to others in the distant past, but there isno harm in restating them to-day.

CORRESPONDENCE

HÆMORRHAGE IN GASTRIC AND DUODENALULCER

To the Editor of THE LANCET

SIR,-In your last issue Hurst and Ryle state thatthe danger of haemorrhage from peptic ulcers has beengrossly exaggerated in papers recently appearingin British journals. I cannot help feeling that thisstatement calls for examination. Hurst, from figurescollected by Babey/ says that the mortality-ratefor cases of peptic ulcer admitted under his care

to Guy’s Hospital on account of recent haemorrhage,and in which death was directly attributable to

haemorrhage, is 4’8 per cent. Compared with thisBabey sets out a table "showing mortality ratesof haemorrhage from ulcer given by various authors "some of which are over 20 per cent. This table is

misleading because no mention is made of the differentcriteria adopted by the various authors when compil-ing their statistics. For example, Conybeare 2 arguingfrom the number of post-mortems of all cases admittedto Guy’s Hospital for haematemesis or melaena from1911 to 1920 (inclusive) showed a mortality of about4-3 per cent. Burger and Hartfall3 3 found the

mortality from severe haematemesis at the same

hospital from 1921 to 1930 (inclusive) to be 22-6 percent. The last figure includes deaths from complica-tions and there seems no useful reason why theyshould be omitted whether from cardiac failure oreven following surgical intervention. It seems quiteclear therefore from a study of the available statisticsthat, omitting cases of melsena, the death-rate inhospitals from severe hsematemesis has not been

1 Babey, A. M., and Hurst, A. F. (1936) Guy’s Hosp. Rep.86, 129.

2 Conybeare, J. J., Quoted by Hurst, A. F. (1923-24) Proc.R. Soc. Med. 17, 20 ; (1924) Lancet, 1, 1095.

3 Burger, G., and Hartfall, J. (1934) Guy’s Hosp. Rep. 84, 167.

exaggerated and is still disturbingly high. Anotherevident fact not stressed by Hurst and Ryle is thatrepeated haemorrhage is the most serious prognosticsign. A single bleeding, however severe, is rarelyfatal. The mortality in Hurst’s cases at Guy’s whichhad further gross bleeding in the wards was 27 percent.With regard to blood transfusion, another important

point dealt with by these authors, we found whenexamining a series of cases (Cullinan and Price 4)and by subsequent experience that when it isconsidered necessary to transfuse because of severeanaemia it is wise to wait until several hours afterthe gross bleeding has ceased. Not only does trans-fusion of itself fail to arrest haemorrhage but it mayeven cause further bleeding if performed immediately.To this rule there is one exception : in cases withsevere anaemia when gradual bleeding has beengoing on for several days transfusion may be a life-saving measure. We also thought that the givingof enemata before the sixth day after a severe

haematemesis carried a risk of further bleeding.I do not wish to imply in any way that because

the mortality in hospitals from severe haematemesisis high that this is any reason for more frequentsurgical intervention. For the reasons Hurst and

Ryle so clearly state immediate operation is veryseldom desirable. Their plea for the avoidance,whenever possible, of disturbing therapeusis and fortreatment with quiet and rest in the widest sense isunassailable. Courage lies not in action but inconfident inaction.

I am, Sir, yours faithfully,EDWARD R. CULLINAN.

4 Cullinan, E. R., and Price, R. K. (1932) St. Bart’s Hosp.Rep. 65, 185.