INNOVATIONS IN BIOMEDICAL MATERIALS 2016

Ceramic and Glass Materials for Implants, Medical Devices and Tissue Engineering

July 28-31, 2016, Rosemont Hyatt, Chicago, IL

ABSTRACTS DUE February 15, 2016: http://bio2016.abstractcentral.com

TRACKS • Orthopedic application • Dental and maxillofacial applications • Material needs medical devices • Advanced manufacturing technologies • Power Sources, energy harvesting, power transmission and telemetry • Implantable and wearable sensors

Endorsed by:

Program Chairs

Roger Narayan, Univ. of

North Carolina, USA

Alessandro Alan Porporati,

CeramTec GmbH, Germany

Markus Reiterer, Medtronic,

PLC, USA

Introduction

The Innovations in Biomedical Materials and Technologies 2016 Meeting, which will take place on July 28-31 at the Rosemont Hyatt (Chicago area), is the third in a series of biomaterial meetings organized by The American Ceramic Society. The meeting will emphasize collaboration between R&D, medical practitioners, and biomedical materials manufacturers/marketers to better develop emerging technologies into marketable products. Cutting-edge research and product developments related to novel materials for orthopedic, dental, and maxillofacial applications; advanced manufacturing technologies; power sources, energy harvesting, power transmission and telemetry; as well as implantable and wearable sensors will be featured. The meeting will highlight three keynote speakers immediately followed by an expert panel session where the audience can interact with renowned experts in the biomedical field. In addition, a robust technical program consisting of six tracks will provide a forum for scientists, engineers, medical professionals, and industrial researchers to discuss recent advances in the field of biomedical materials is planned. Abstracts are welcome until the February 15th deadline. This meeting is endorsed by the European Ceramic Society, the Orthopaedic Research Society, and the Society for Biomaterials.

Keynote and Panel Discussions

THE ROLE OF MATERIALS SCIENCE IN TREATMENT OF CHRONIC DISEASE

Disease of the motion apparatus (large joint, spine, dental)

Cardiovascular

Endocrinological (Diabetes)

Infection in Arthroplasty

Technical Tracks

Track 1: ORTHOPEDIC APPLICATION – WHERE ARE WE? WHERE DO WE NEED TO GO? Bioceramics are currently applied in high volume orthopedic applications such as bearing couples for total joint replacement, because of their high wear and scratch resistance coupled with high biocompatibility. The ceramic articulations have also shown to be a safe and proven technology. However, there is substantial room for improvement to reach their full potential and being introduced in other fields of orthopedics. Nevertheless, the design and engineering of these materials are already in progress with a focus on obtaining optimized properties which better respond to external, biologically compatible stimuli (physical, chemical, biological). Reaching this goal depends heavily on interdisciplinary contributions from material science, chemistry, physics, biology and medicine, which depend on mutually beneficial scientific exchange. The session is aimed to address the key challenges using a comprehensive approach that will embrace both bioinert and bioactive ceramics and will focus on the effect of biodegradation, engineering of material surfaces to promote osteointegration and osteosynthesis as well as mitigating bacteria biofilm formation.

The topics of the session include:

New materials and bioinspired structures

Biodegradation

Surface modification for better cell-material interaction

Bacteria anti-adhesion strategies

Novel ceramic applications in orthopedics

Biomechanics

Clinical outcomes of bioceramics

Mechanical properties of advanced bioceramics Track Chair: Alessandro Alan Porporati, CeramTec GmbH, Plochingen, Germany

Track 2: DENTAL AND MAXILLOFACIAL APPLICATIONS In recent years, there has been intensive research and clinical activity in the areas of biomedical ceramics and maxillofacial materials. A noteworthy feature of this track will be new biomedical ceramics for cell scaffolds. Sessions for both materials areas will be devoted to processing, including imaging, computerized planning and three-dimensional printing, along with the traditional areas of materials characterization and clinical results. An opening plenary session will have presentations from distinguished investigators in biomedical ceramics, maxillofacial materials, and other current biomedical materials areas. Both oral and poster sessions will be included, along with a panel discussion about current research and future directions. Abstracts on dental alloys and other polymeric dental materials will also be considered for this track, which will include current active areas of dental materials research.

Track Chairs: William A. Brantley, The Ohio State University College of Dentistry, Columbus, Ohio, USA and J. Robert Kelly, University of Connecticut School of Dental Medicine, Farmington, CT, USA

Track 3: MATERIAL NEEDS FOR MEDICAL DEVICES In the last two decades tremendous progress has been made in field of bioactive and biomimetic materials and in understanding natural/biologic materials. On the other hand, most of the medical devices that improve people’s lives such as pacemakers, cardiac stents, heart valves, and large joint replacements utilize a fairly small set of conventional materials subjected to traditional problems in materials science. Due to the extremely high reliability goals, the complex use conditions, and long implant durations, it is often very difficult accurately predict the product performance. This track includes topics covering the control and prediction of fatigue, corrosion, tribology, biostability, and biocompatibility of implants and complex medical devices. Contributions on metals, ceramics, polymers and multi-material systems are welcome. Track Chair: Markus Reiterer, Medtronic, PLC, USA

Track 4: ADVANCED MANUFACTURING TECHNOLOGIES Industrial and academic researchers have recently examined the use of novel manufacturing technologies to overcome the limitations associated with conventional manufacturing processes. For example, technologies that involve fabrication of three-dimensional structures through additive joining

of materials in a layer-by-layer manner have garnered significant interest from the biomedical manufacturing community. This track will consider recent developments in coating, surface modification, machining, and additive manufacturing of biomedical materials as well as other novel manufacturing processes. Use of these technologies for processing materials used to make implants, medical instruments, biosensors, drug delivery devices, tissue engineering scaffolds, and other medical devices will be considered.

Track Chair: Roger Narayan, University of North Carolina, Raleigh, NC, USA

Track 5: POWER SOURCES, ENERGY HARVESTING, POWER TRANSMISSION AND TELEMETRY Over the last few decades, medical component and device systems have evolved from simple data acquisition devices to complex multi-functional healthcare systems. A fundamental requirement for successful operation of these healthcare systems is adequate and reliable operation of power sources, power transmission and telemetry. Major advances, for example in the power source area, include the matured and dominant lithium batteries, as well as the emerging flexible batteries, energy harvesting and remote powering. The goal of the track is to create an open forum dedicated to bringing all interested parties to discuss the technical challenges and future directions in these areas. The interest of this track includes, but is not limited to, the following topics:

New materials and packaging for primary and secondary lithium batteries Flexible batteries and super-capacitors Energy harvesting and remote powering for wireless medical devices Wireless medical telemetry services Bluetooth low energy technology Medical sensor networks; multi-hop, relay and cooperative data transmission Real-time sensing, diagnosis, prognosis, and control of power sources

Track Chair: Chao Hu, Iowa State University, Ames, IA, USA

Track 6: IMPLANTABLE AND WEARABLE SENSORS With the adoption of cell-phones, wireless devices, and microelectronic technology by a significant percentage of humanity, there is a huge opportunity for associated biosensors to change the way that personal health is assessed and medical treatments are administered. Moreover, the need to reduce healthcare costs and to expand access to healthcare (especially in developing markets) creates a strong potential need for biosensors. For biosensors to be useful, they must be affordable, easy to use, reliable, and sufficiently accurate for their intended applications. While wearable activity trackers, blood glucose sensors, blood pressure cuffs, and pulse oximeters are visible examples of this technology, there are many other electrical, mechanical, and optical biosensors being developed in both industry and academia. One challenge for the adoption of biosensors is to optimize the materials used in their construction to minimize cost and maximize function. This track covers the application of metals, ceramics, polymers and multi-material composites in biosensors (non-invasive, minimally invasive, or implantable) to meet this challenge. Examples of the evaluation of material and sensor performance in bench, animal, and human experiments are also welcome. Track Chair: Shawn C. Kelley, Medtronic PLC, USA