Klinik und Poliklinik für Augenheilkunde

All authors have no financial interest in the subject matter of this poster.

R. Khoramnia, J. P. Salgado, C.P. Lohmann, C. Winkler von Mohrenfels

ASCRS 2011

Comparison Between Central Corneal Thickness Measurements in Healthy Eyes Using a New Device and 2 Other Methods

Purpose

Klinik und Poliklinik für Augenheilkunde

The TMS-5 (Tomey) is a new device for the examination of the anterior eye

segment combining Placido- and Scheimpflug-Technology. The purpose of this

study was to compare central corneal thickness (CCT) measurements using

TMS-5, LenStar/Allegro Biograph (Haag-Streit/WaveLight), and the gold

standard ultrasonic pachymetry (Pachymeter SP-3000, Tomey).

TMS-5

Foto: www.ophthalworld.de

Allegro Biograph/LenStar

Foto: www.wavelight.com

SP-3000

Foto: www.eyenovation.de

Material and methods

Klinik und Poliklinik für Augenheilkunde

48 eyes of 24 healthy volunteers were included in this comparative study. In all

eyes, CCT was measured with the TMS-5 (Tomey, Nagoya, Japan), LenStar

(Haag-Streit AG, Koeniz, Switzerland)/Allegro Biograph (WaveLight AG,

Erlangen, Germany), and ultrasonic pachymetry (Pachymeter SP-3000, Tomey,

Nagoya, Japan). The values obtained from the different devices were compared

using Bland-Altman plots and linear regression.

Results I

Klinik und Poliklinik für Augenheilkunde

The mean CCT readings with the TMS-5, LenStar/Allegro Biograph, and

ultrasound were 516.6 µm, 535.7 µm, and 543.6 µm, respectively.

Regression analysis showed a high correlation between the values

obtained with the TMS-5 and the LenStar/Allegro Biograph (r=0.950,

p<0.001) and the values obtained with the TMS-5 and ultrasound (r=0.918,

p<0.001).

Results II

Klinik und Poliklinik für Augenheilkunde

Compared to the LenStar/Allegro Biograph and ultrasound, the TMS-5

underestimated the CCT. The mean differences were -19.1 µm compared

to the LenStar/Allegro Biograph and -27.0 µm compared to ultrasound as

shown in the Bland-Altman plots.

Conclusion

Klinik und Poliklinik für Augenheilkunde

• Regression analysis showed a high correlation between the values obtained with

the TMS-5 and the LenStar/Allegro Biograph and the values obtained with the

TMS-5 and ultrasound.

• However, the TMS-5 underestimated the CCT compared to the LenStar/Allegro

Biograph and ultrasound.

Therefore, the TMS-5, LenStar/Allegro Biograph, and ultrasound should not

be used interchangeably for the measurement of CCT.

Name der KlinikKlinik und Poliklinik für Augenheilkunde

Contact:

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