Predispozitie genetica HLA B 8, DRw 2, 3, 4, 5 Deficiente de complement Clr, Cls, C4, C2, C3F, C5, C8 Infectii virale si bacteriene Antigene X Medicamente Factori endocrini Ultraviolete Denaturare de ADN cutanat Activarea limfocitelor B Deficite in cooperarea T si B Autoantic orpi Piele, rinichi, seroase, articulatii, cord, SNC Prostaglandine Kinine Amine vasoactive Inflamati e Limfotoxine Limfokine Autoanticorpi Reactie de tip II, IV sau limfocitotox dependenta de anticorpi Reactie de tip III Complexe imune ETIOPATOGENIA BOLILOR AUTOIMUNE
Predispozitie geneticaHLA B 8, DRw 2, 3, 4, 5Deficiente de
complementClr, Cls, C4, C2, C3F, C5, C8Infectii virale si
bacterieneAntigene XMedicamenteFactori
endocriniUltravioleteDenaturare de ADN cutanatActivarea
limfocitelor BDeficite in cooperarea T si BAutoanticorpiPiele,
rinichi, seroase, articulatii, cord, SNCProstaglandineKinineAmine
vasoactiveInflamatieLimfotoxineLimfokineAutoanticorpiReactie de tip
II, IV sau limfocitotoxica dependenta de anticorpiReactie de tip
IIIComplexe imuneETIOPATOGENIA BOLILOR AUTOIMUNE
