NCM MEDICINE

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NCM MEDICINE M.AMBAGA, A.TUMEN-ULZII

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Socrates: there is only one good: knowledge and the only evil: ignorance.

INTRODUCTION

It is time to solve all problems of medicine, relating to the normal existence, disturbance of normal

existence of human body, their diagnosis and treatmen by using fully membered equition 8 which include

a G knowledge + X knowledge + S - knowledge + s-NCM knowledge.

Definition of NCM-newly coded medicine.

NCM-newly coded medicine is triple medical system, composedof Traditional Medicine (TM) in the full

form, also Modern medicine (MM) in the full form and in addition s-NCM new knowledge based

medicine (NKBM), implemented a every day diagnostic and treatment functions by using a three kind

approaches as TM, MM, NKBM together, and their scientific-theoretical basis is strongly connected with

s-NCM new knowledge as new definition of living cells, completely explaining the essence of normal

existence of living cells and simultaneously revealing and discovering the essence of basic theoretical

aspects of Traditional Medicine and Modern medicine, not allowing the mixing and neutralizing

theoretical aspects of both medicine, preserving the unique specificity of their theoretico-practical aspects

and therminological specifics, meanwhile not separating each other.

In recent years, a renewed interest and attention by many scientists of our and foreign countries aredirected towards the establishment of scientific essence of theoretical problems of Tibetan-Mongolian

Traditional Medicine /TMTM/ in strong connection with theory of Contemporary Biology and Medicine

by proposing the new knowledge based model of living cells.

A number of these theoretical problems belongs the theory of five element and the theory rlung, Mkhris,

Badgan.

In this connection a question rises what interorganism's microstructure related morpho-functional unit i.e.

new knowledge based model of living cells plays the role of real material, objective substance, which

leads to the appearance of universal theory of five elements and rlung, mkhris badgan. i.e. the external

properties formed in which morpho-functional unit, structure, revealed by new knowledge, had

perceived and summarized as general characteristics of rlung, mkhris, badgan (so named X- knowledge),

so named 20 external patterns (so named G- knowledge) in traditional medicine 3000 years ago.

And so, recently scientists from many countries are remained, not able to find this whole organisms

unique functional - structural bioequivalents, to propose the new model of living cells, which was

reflected in the theory of rlung, Mkhris, Badgan, which in three forms of existence can be show all the

external signs as hot, cold, heavy, mobile summarized and abstractized by wind like rlung, fire-sun like

mkhris and water-moon like Badgan thermin.

There are reasons to say that the appearing of abstract theory of Rlung, Mkhris, Badgan in Tradititional

medicine 3 thousand years ago - follow from the functioning of membrane -redoxy potentials three state

line systems in the first compartment with close relationship with fourth and second, third compartments

in human body, revealed by s-NCM new knowledge based model of living cells.

To decide a main logical cognitive key points of research works, directed to find the scientifico-methodological basis of Newly Coded Medicine (NCM) was planned to conduct the our study in such

interconnectable ways:

1. The first principally important step of our works was a detection of evolutionary very important-

constantly developed general characteristics of living cells, which may be reflected in the theory of

rlung, mkhris, badgan of Tibetan Mongolian Traditional medicine.

2. The second principally important step of our works was a revealing the functional and structural unit of

living cells, which may be reflected in the theory of Tibetian - Mongolian Traditional medicine in the

following philosophical context as wind - like mobile, unoilly, light nature-external characteristics of

human body, symbolized by rlung abstract thermin, sun-like hot, hot oilly nature-external characteristics


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of human body, symbolized by mkhris abstract thermin, moon-like cool, heavy, cold oily nature-external

characteristics of human body, symbolized by badgan abstract thermin.

3. The next principally important step of our works was establish a scientific basis of new enriched

definition of living cells, which are included the functional and structural unit of living cells of human

body, which may be expressed in the theory of Tibetan Mongolian Traditional medicine by abstract

thermins as rlung, mkhris, badgan.

Considering the above mentioned general line of wide scale investigations and difficulties in the studying

of theory of Traditional Medicine, we are setting the following concrete goals:

- To reveal this material substances, which existed inside of human body and conditioned all external

signs of "rlung, Mkhris, Badgan" according to theory of Traditional Medicine /TM/, revealed by s-NCM

new knowledge based model of living cells

To establish scientific matter of abstract notion of (rlung, Mkhris, Badgan), regarding to the age,

season, diets, signs and causes of disease, 'specificity of solid organs and individuals in close connection

with the functional properties, which formed on the level of "such material substances", revealed by s-

NCM new knowledge based model of living cells.

To elaborate the new principles of prevention and treatment of obesity, ageing and cancer within

s-NCM new knowledge based model of living cells, which are existed as "central cognitive-knowledgebridge" between theoretical, diagnostic and treatment aspects of Traditional and Modern medicine.

Results of investigation

1. Fluid alpha state of membrane structures with high level of oxidation potential with high level of

heat energy formation, with high level of proton leak, proton conductance, with middle intensity of

high energy phosphate - ATP generation, of high energy electrons - NADPH generation.

:

By using comparative analytical methods, we demonstrated in 1990 for the first time and eventually

confirmed that whole body's membrane-redoxy potentials 3 state line system, which existed in the three

basic states as:

2. Solid betta - state of membrane structures with high level of reduction potential with middle level

of heat energy formation, with low level of proton leak, proton conductance, with high intensity of

high energy phosphate-ATP generation, of high energy electrons - NADPH generation.

3. Intermediate gamma state of membrane structures with low level of oxidation-reduction potential

with low level of proton gradient generation, low level of heat energy formation, with low intensity of

high energy phosphate - ATP generation, with low intensity of high energy electrons - NADPH

generation could play the role of such a biological substance, relating to theory of 5 element and theory

of rlung, mkhris, badgan.

A. Fluid - alpha state of membrane structures with high level of oxidation potential with high level of

heat energy formation, with high level of proton leak, proton conductance, with middle intensity of

high energy phosphate - ATP generation, of high energy electrons - NADPH generation, it's hot, hot oil,

acute external functional properties corresponds to the fire element related - sun like mkhris abstract

notion.B. Solid betta - state of membrane structures with high level of reduction potential with high middle

level of heat energy formation, with low level of proton leak, proton conductance, with high intensity

of high energy phosphate - ATP generation, of high energy electrons - NADPH generation, it's cool,

cold oil, heavy, stupid external functional properties summarized under the water-earth elements

related-moon like badgan abstract notionof badgan.

C. Intermediate gamma state of membrane structures with low level of oxidation-reduction potential

with low level of proton gradient generation, low level of heat energy formation, with low intensity of

high energy phosphate - ATP generation, of high energy electrons - NADPH generation and heat


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energy, its mobile, unoilly, light external functional properties is symbolized under the wind element

related - wind like rlung abstract notion.

Scientic essence of our new suggestion lies in discovering "those material subjects" and revealing this

secrets of theory of Rlung-Mkhris-Badgan, why under only similar thermin of rlung-Mkhris-Badgan in

Oriental and Mongolian traditional medicine had expressed more different things, including the whole

organism's regulatory function, seasonal, age and daily changes, specific appearance of R.M.B in

individuals and five sold organs, signs of disease, causes of disease, provocation's and dietary factors.

Abovementioned discovery summarized within s-NCM new knowledge was the scientifico-

methodological basis to laid foundation of new integrated triple medical system-NCM medicine.

What is specificity of new integrated triple medical system-NCM which at first developed by us:

a. Consisted of of traditional (X and G - knowledge based) and modern medical system (S-knowledge

based) integrated through s-NCM new knowledge.

b. Decided all diagnostic and treatment problems using triple approaches as tradinal (X and G-

knowledge based) and modern medical system (S-knowledge based) integrated through s-NCM new

knowledge. What is specificity of membrane - redoxy potentials three state line systems, which at

first revealed by us:

Consisted of H,e donators as foods and H,e acceptors as oxygensa.Ensured normal flow of protons and electrons from donators to acceptors with generation of high

energy phosphate-ATP, high energy electrons NADPH and heat energy

b.Functioned with using a glycolysis, Krebs cycle, oxidative deamination and betta oxidation reaction to

generate normal flow of protons and electrons.

c.Provided the normal maintainance of living processes.

d. Existed in three interconvertible states:

- fluid alpha state, consisting of mainly unsaturated fatty acids, conditioning a high levels of oxy

potentials and with high levels of proton, electrons conductance and high levels of heat energy release,

middle degree of energy accumulation and middle degree of high energy phosphate-ATP, high energy

electrons NADPH, with middle ratio of donators : accceptors.

- solid betta state, consisting of mainly saturated fatty acids, conditioning a high levels of red potentials

and with slow levels of proton, electrons conductance and low levels of heat energy release, high

degree of energy accumulation and high degree of high energy phosphate -ATP, high energy electrons

NADPH, with increased ratio of donators : acceptors - gamma state, consisting of decreased contents of

saturated-unsaturated fatty acids, conditioning a decreased levels of redoxy potentials and with slow

levels of proton, electrons conductance and low levels of heat energy release and energy accumulation

and low degree of high energy phosphate - ATP, high energy electrons NADPH, with decreased contents

of donators: accceptors, increased significance of proton, electrons prior to generation of proton

gradients, prevailed slip mecchanism.

D. What is specificity of abstract theory of Rlung, Mkhris, Badgan:

a. Described a general pattern of maintainance of normal living processes with participation ofmembrane-redoxy potentials three state line systems, ensuring normal flow of protons and electrons from

donators to acceptors with generation of high energy phosphate - ATP, high energy electrons NADPH

and heat energy through carbohydrate glycolysis, Krebs cycle, oxidative deamination of aminoacids and

betta oxidation of fatty acids .

b. Described a general pattern of normal functioning of living system with participation of 5 membrane

structures-5 function systems, ensuring normal genetic-cell devision, information -response,

biosynthetical, bioenergetical, biotransformation functions by using of high energy phosphate-ATP, high

energy electrons NADPH and heat energy, generated in membrane-redoxy potentials three state line

systems.


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E.What is coincidence between abstract theory of Rlung, Mkhris, Badgan and membrane - redoxy

potentials three state line systems in the first compartment, which at first revealed by us:

a. Fluid alpha states, consisting of unsaturated fatty acids with high levels of oxy potentials and with

high levels of proton, electrons conductance and high levels heat energy release, middle degree of energy

accumulation and middle degree of high energy phosphate-ATP, high energy electrons NADPH, with

middle ratio of donators: accceptors are associated with abstract theory of Mkhris, which is distinguished

by hot, hot oil, acute external characteristics.

b. Solid betta state, consisting of mainly saturated fatty acids, conditioning a high levels of red

potentials and with slow levels of proton, electrons conductance and low levels of heat energy release,

high degree of energy accumulation and high degree of high energy phosphate-ATP, high energy

electrons NADPH, with increased ratio of donators : accceptors are associated with abstract theory of

Badgan, which is distinguished by cool, cold oil, stupid external characteristics.

c. Gamma state, consisting of decreased contents of saturated - unsaturated fatty acids,

conditioning a decreased levels of redoxy potentials and with slow levels of proton, electrons

conductance and low levels of heat energy release and energy accumulation and low degree of high

energy phosphate-ATP, high energy electrons NADPH, with decreased contents of donators: accceptors,

increased significance of proton, electrons prior to generation of proton gradients, prevailed slipmecchanism are associated with abstract theory of rlung, which is distinguished by light, mobile , nonoil,

cool external characteristics.

The scientifico-methodological basis of newly coded medicine (NCM) is characterized by following

novelty:

1. In the result of proposing the new enriched definition of living cells within s-NCM new knowledge,

which clarified that main key regulating mechanism of living cells are a three states of membrane-

redoxy potentials, providing a normal flow of protons and electrons, by us has been established that

between the quantative proportion of abstractized first compartment related rlung, mkhris, badgan

code and some parameters of cell membrane redoxy potentials, located intercellularly in first

compartment are existed the more strong correlation as: the elevated quantative proportion of

abstractized by mkhris diagnostic parameters is associated with high oxy potentials (first

compartment), the increased quantative proportion of abstractized by rlung diagnostic parameters is

accompanied with slow redoxy potentials (first compartnent), the elevated quantative proportion of

abstractized by badgan diagnostic parameters is associated with high red potentials (first compartnent)

in the healthy persons

2. It has been revealed that between the quantative proportion ofof abstractized second compartment

related rlung, mkhris, badgan code and some parameters of of cell membrane redoxy potentials, located

extracellularly in second compartment are existed the more strong correlation as: a.the elevated

quantative proportion of abstractized by rlung code, located outside of cells is associated with low redoxy

potentials (second compartment), expressed as a low internal and external adipocyte tissues, Rid formula,urine and serum oxidase enzyme activity, urine ph, resistance of membrane structures, high concentration

of deprotonizid products in the membrane structures, low level of serum cholesterol, triglycerids in the

Healthy persons. An all above mentioned code correlation as abstract thermins as rlung, mkhris, badgan

- a three states of membrane- redoxy potentials of living cells serves the main scientifico-methodological

basis of Newly Coded Medicine (NCM), which originated in the integration of traditional and recent

medicine, but principally distinguished from traditional and recent medicine, taken separately.


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Picture 1

Betta state

ABSTRACTION IN THE FORM OF APPEARANCE OF THEORY

OF RLUNG, MKHRIS, BADGAN (YANG-YIN)

FIRE ELEMENT RLUNG ELEMENT WATER, EARTH ELEMENT

Acute, hot Unoill characreistics Cold, heav characteristics

The intensification of the

thermogenesis and

activation of whole

organisms functional

level

The prevalence of

gamma state of MS

with low redoxy

potentials

The relatively limitation of the

thermogenesis, intensification of

energy accumulation, decrease of

functional activity of human body

Whole organisms level

Organs level

Tissues level

Al ha Gamma

The basic three states of membrane redoxy potential 3 state system


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New integrated triple medical system (NCM) Picture 2

A.What is specificity of new cognitive steps as: Really existed substance - revealing of external

patterns - intelectually transformation of these to the first variant of abstraction as 5 elements,

transformation of these to the second variant of abstraction as Rlung, Mkhris, Badgan.

According to the new cognitive steps, formulated by us as: Really existed substance (S) - revealing of

20 external patterns (EP) - abstractized transformation of these to the first variant of abstraction as 5

elements (A-1), abstractized transformation of these to the second variant of abstraction as Rlung,Mkhris, Badgan (A-2) when within membrane - redoxy potentials 3 state line system, that provide the

normal existence of all cells by ensuring normal flow of electrons, protons with generating the proton

gradient have been prevailed :

1. The fluid alpha state of membrane structures with high oxidation potential, high level of proton

conductance and high level of proton leak play role of Really existed substance (S), because of this

among 20 external patterns (EP) prevailed 7 patterns as hot, hot oil, acute et all, which at first were

abstractized by hot - fire element among 5 elements (A-1), at second were abstractized by fire element

related moon like mkhris (A-2).

2. The solid betta state of membrane structures with high reduction potential, middle level of proton

conductance and middle level of proton leak play role of Really existed substance (S), because of this

among 20 external patterns (EP) dominated 7 patterns as cold, cold oil, heavy, stupid et all, which at first

were abstractized by cold-heavy earth, water elements among 5 elements (A-1), at second were

abstractized by earth, water element related moon like badgan (A-2).




were abstractized by light, mobole wind element among 5 elements (A-1), at second were abstractized

by wind element related rlung (A-2).

B. What is specificity of s-NCM new knowledge, which at first proposed by us:

a. Described a living cells and living organism as complex system, consisting of 4 basic compartments.

b.1. First compartment, named as membrane-redoxy potentials three state line systems, ensuring normalflow of protons and electrons from donators to acceptors with generation of high energy phosphate-ATP,

high energy electrons NADPH and heat energy through glycolysis reaction, Krebs cycle, oxidative

deamination and betta oxidation reactions.

b. 2. Fourth compartment, named as 5 membrane structures-5 function systems, ensuring normal

genetic-cell division, information-response, biosynthetical, bioenergetical, biotransformation functions by

using of high energy phosphate-ATP, high energy electrons NADPH and heat energy, generated in

membrane-redoxy potentials three state line systems.

c. Second compartment consists of serum and extracellular system, where donators, acceptors and some

metabolites formed in the result of functioning of 5 of membrane structures-5 function systems,


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including biosynthetic, bioenergy, biotransformation functions, also products of AO-SPOL system

temporarely existed.

d. Third compartment consists visceral and under skin fatty acids, where donators, acceptors, products of

AO-SPOL system are existed relatively constant.

Developing by us the new knowledge as s-NCM new knowledge gives the possibility a integration of

traditional and modern medicicne through it.

C. What is specificity of membrane - redoxy potentials three state line systems, which at first

revealed by us:

Consisted of H,e donators as foods and H,e acceptors as oxygens

a.Ensured normal flow of protons and electrons from donators to acceptors with generation of high

energy phosphate-ATP, high energy electrons NADPH and heat energy

b.Functioned with using a glycolysis, Krebs cycle, oxidative deamination and betta oxidation reaction to

generate normal flow of protons and electrons.

c.Provided the normal maintainance of living processes.

d. Existed in three interconvertible states:

- fluid alpha state, consisting of mainly unsaturated fatty acids, conditioning a high levels of oxy

potentials and with high levels of proton, electrons conductance and high levels of heat energy release,middle degree of energy accumulation and middle degree of high energy phosphate-ATP, high energy

electrons NADPH, with middle ratio of donators : accceptors.

- solid betta state, consisting of mainly saturated fatty acids, conditioning a high levels of red potentials

and with slow levels of proton, electrons conductance and low levels of heat energy release, high

degree of energy accumulation and high degree of high energy phosphate -ATP, high energy electrons

NADPH, with increased ratio of donators : acceptors - gamma state, consisting of decreased contents of

saturated-unsaturated fatty acids, conditioning a decreased levels of redoxy potentials and with slow

levels of proton, electrons conductance and low levels of heat energy release and energy accumulation

and low degree of high energy phosphate - ATP, high energy electrons NADPH, with decreased contents

of donators: accceptors, increased significance of proton, electrons prior to generation of proton

gradients, prevailed slip mecchanism.

D. What is specificity of abstract theory of Rlung, Mkhris, Badgan:

a. Described a general pattern of maintainance of normal living processes with participation of

membrane-redoxy potentials three state line systems, ensuring normal flow of protons and electrons from

donators to acceptors with generation of high energy phosphate - ATP, high energy electrons NADPH

and heat energy through carbohydrate glycolysis, Krebs cycle, oxidative deamination of aminoacids and

betta oxidation of fatty acids .

b. Described a general pattern of normal functioning of living system with participation of 5 membrane

structures-5 function systems, ensuring normal genetic-cell devision, information -response,

biosynthetical, bioenergetical, biotransformation functions by using of high energy phosphate-ATP, high

energy electrons NADPH and heat energy, generated in membrane-redoxy potentials three state linesystems.

E.What is coincidence between abstract theory of Rlung, Mkhris, Badgan and membrane - redoxy

potentials three state line systems in the first compartment, which at first revealed by us:

a. Fluid alpha states, consisting of unsaturated fatty acids with high levels of oxy potentials and with

high levels of proton, electrons conductance and high levels heat energy release, middle degree of energy

accumulation and middle degree of high energy phosphate-ATP, high energy electrons NADPH, with

middle ratio of donators: accceptors are associated with abstract theory of Mkhris, which is distinguished

by hot, hot oil, acute external characteristics.


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b. Solid betta state, consisting of mainly saturated fatty acids, conditioning a high levels of red

potentials and with slow levels of proton, electrons conductance and low levels of heat energy release,

high degree of energy accumulation and high degree of high energy phosphate-ATP, high energy

electrons NADPH, with increased ratio of donators : accceptors are associated with abstract theory of

Badgan, which is distinguished by cool, cold oil, stupid external characteristics.

c. Gamma state, consisting of decreased contents of saturated - unsaturated fatty acids,

conditioning a decreased levels of redoxy potentials and with slow levels of proton, electrons

conductance and low levels of heat energy release and energy accumulation and low degree of high

energy phosphate-ATP, high energy electrons NADPH, with decreased contents of donators: accceptors,

increased significance of proton, electrons prior to generation of proton gradients, prevailed slip

mecchanism are associated with abstract theory of rlung, which is distinguished by light, mobile , nonoil,

cool external characteristics.

I. What is coincidence between abstract theory of Rlung, Mkhris, Badgan and Fourth

compartments parameters, which at first revealed by us:

a. Change of fourth compartment parameters, named as 5 membrane structures-5 function systems,

ensuring normal genetic-cell division, information-response, biosynthetical, bioenergetical,

biotransformation functions by using of high energy phosphate - ATP, high energy electrons NADPH andheat energy, generated in membrane - redoxy potentials three state line systems in the form of decrease of

synthetic, bioenergy, biotransformation functions and of unregulated disturbance of information-

response functions are coded by abstract Rlung code in the Tibetian Mongolian Traditional medicine.

b. Change of fourth compartment parameters, named as 5 membrane structures - 5 function systems,


biotransformation functions by using of high energy phosphate-ATP, high energy electrons NADPH and

heat energy, generated in membrane-redoxy potentials three state line systems in the form of unregulated

intensification of information-response functions are coded by abstract Mkhris code.

c. Change of fourth compartment parameters, named as 5 membrane structures-5 function systems,


biotransformation functions by using of high energy phosphate-ATP, high energy electrons NADPH and

heat energy, generated in membrane-redoxy potentials three state line systems in the form of slowing of

information-response functions are coded by abstract Mkhris code in the Tibetian Mongolian Traditional

medicine.

L.What is coincidence between abstract theory of Rlung, Mkhris, Badgan and second compartments

parameters, which at first revealed by us:

a. Change of second compartment parameters, consisting of serum and extracellular system, where

donators, acceptors and some metabolites formed in the result of functioning of 5 membrane structures -

5 function systems, ensuring normal genetic - cell division, information - response, biosynthetical,

bioenergetical, biotransformation functions in the form of decrease of contents of donators, acceptors and

some metabolites formed in the result of functioning of 5 of membrane structures-5 function systems,including synthetic, bioenergy, biotransformation functions are coded by abstract Rlung code in the

Tibetian Mongolian Traditional medicine.

b. Change of second compartment parameters consisting of serum and extracellular system, where

donators, acceptors and some metabolites formed in the result of functioning of 5 membrane structures-5

function systems, ensuring normal genetic-cell division, information-response, biosynthetical,

bioenergetical, biotransformation functions in the form of increase of contents of donators, decrease of

acceptors and increase of AO - decrease of SPOL system are coded by abstract Badgan code in the



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c. Change of second compartment parameters consisting of serum and extracellular system, where

donators, acceptors and some metabolites formed in the result of functioning of 5 membrane structures-5

function systems, ensuring normal genetic-cell division, information-response, biosynthetical,

bioenergetical, biotransformation functions in the form of decrease of contents of donators, increase of

acceptors and decrease of AO - increase of SPOL system are coded by abstract Badgan code in the


L. What is coincidence between abstract theory of Rlung, Mkhris, Badgan and Third

compartments parameters, which at first revealed by us:

a. Change of Third compartment parameters in the form of decrease of visceral and external under skin

fatty acids, also donators, acceptors are coded by abstract Rlung code in the Tibetian Mongolian

Traditional medicine.

b. Change of Third compartment parameters in the form of increase of saturated class of visceral and

external under skin fatty acids, also increase of donators, decrease of acceptors are coded by abstract

Badgan code in the Tibetian Mongolian Traditional medicine.

c. Change of Third compartment parameters in the form of increase of unsaturated class of visceral and

external under skin fatty acids, also decrease of donators, increase of acceptors are coded by abstract

Mkhris code in the Tibetian Mongolian Traditional medicine.In such way we should recognize that appearing of abstract theory of Rlung, Mkhris, Badgan in

Tradititional medicine 3 thousand years ago - follow from the functioning of membrane-redoxy

potentials three state line systems in the first compartment with close relationship with fourth and second,

third compartments in human body

M. What is life process according to new integrated triple medical system - NCM which at first

developed by us:

Life is specific process, occurred in living cells, appeared as normal conductance of electrons and protons

with participation of electrons and protons donators (food intake) - acceptors (breathihg-oxygens),

which needs membrane-redoxy potentials three state line systems, which leads to formation of ATP,

NADPH, heat energy, which creates the basis to formation of action potential-nervous impulse

generation-propagation and cell division, bioenergetical, biotransformation functions.

N. What is lifekeeping rlung according to new integrated triple medical system - NCM which at

first developed by us:

Life keeping rlung is specific notion of theory of Traditional medicine formed in result of imagination of

ancient philosophers indicating a how human body works and regulate, ensure the normal conductance

of electrons and protons with participation of electrons and protons donators (food intake) -acceptors

(breathihg-oxygens), which needs membrane-redoxy potentials three state line systems inside of living

cells, which leads to formation of ATP, NADPH, heat energy, which would create the basis to formation

of action potential-nervous impulse generation-propogation and cell division, bioenergetical,

biotransformation functions.

O. New definition of living cells according to new integrated triple medical system - NCM which atfirst developed by us:

Living cells are functional - structural unit of human body, consisting from membrane - redoxy potentials

three state line systems, which ensure constant flow of electrons and protons between Donators and

Acceptors with producing high energy phosphate - ATP, high energy electrons - NADPH, heat energy,

thereby able to maintain normal occuring of information - response function in plasmic membrane,

genetic - cell division function in nucleus membrane, biotransformation function in microsomal

membrane and biosynthetic - rebiosynthetic function in ribosomo-microsomal and lisosomo-pereoxisamal

membrane, bioenergetical function in mitochondrial membrane, beside all their important molecules have

general nucleoside + phosphate structures.


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U. What is x, g, S, s-NCM stage of developing of medical thinking of humanity according to new

integrated triple medical system - NCM which at first developed by us:

In the framework of NCM medicine we also untroduce the therminology as x, g, S, s-NCM period time -

stage of developing of medical thinking of humanity, which made of chronology of appearing a more

important time interval of developing and foundation of traditional and modern, also NCM medicine

much clearer than it have been before.

G-period is time of appearing of theory of 20 external patterns of Traditional medicine, X- period is time

of appearing of theory of 5 elements and abstract theory of Rlung, Mkhris, Badgan of Traditional

medicine, when yet not formed knowledge as s - NCM knowledge, also Modern medical knowledge as

S.

S-period is time of appearing and developing of Modern medicine, which are not used knowledge as X

and G knowledge.

S-NCM period is time of developing and establishing of NCM medicine, which used Tradiditional

medical knowledge as X, G, Modern medical knowledge as S and new s - NCM knowledge all together,

through it have been integrated all medical knowledge, formed during all time of developing of medical

systems.

U. What is definition of Traditional medicine.Owing to foundation of NCM medicine became clear that such very important regulations as gene in the

one side, Rlung, Mkhris, Badgan in the another side, also such scientific knowledge as genetics and

Traditional medicine existed in the one unseparable cognitive chains, consisting of whole 6 steps, started

by gene regulation in the 1 step - ended by Rlung, Mkhris, Badgan coding in the therminal 6 step.

Traditional medicine is medical system originated by abstractizing and transforming a different external

patterns, appeared in outside of human body because of variety of enzyme - substrates relationship in the

living cell level, manufactured under information - instruction - signalling functions of corresponding

genes, in the first case by 5 elements as fire, water, earth, wind, in the second case by moon like badgan

coding, sun like Mkhris coding, wind like Rlung coding.

Picture 2

In the frame work of new conception of the "rlung, Mkhris, Badgan-membrane structure-redoxy

potentials 3 states "we have managed to explain the membrane-redoxy potential based mechanism of

The theoryrlung, Mkhris, Badgan

A

Generalcharacteristics

Solid organs

Season

Age

Constitution

type ofindividuals

Dietary factors

Medicaments

B

The all recent

informations,

regarding to

regulation function

of membrane

redoxy potential 3

state regulation of

human body


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theory of TMTM in relation to taste and power, property of old medicaments and pulse diagnostic

methods.

According to the new cognitive steps, formulated by us as: Really existed substance (S) - revealing of

20 external patterns (EP) - intelectually transformation of these to the first variant of abstraction as 5

elements (A-1), transformation of these to the second variant of abstraction as Rlung, Mkhris, Badgan(A-

2) when within membrane - redoxy potentials 3 state line system, that provided the normal existence of

all cells by ensuring normal flow of electrons, protons with generating the proton gradient have been

prevailed :

1. The fluid alpha state of membrane structures with high oxidation potential, high level of proton

conductance and high level of proton leak play role of Really existed substance (S), because of this

among 20 external patterns (EP) prevailed 7 patterns as hot, hot oil, acute et all, which at first were

abstractized by fire element among 5 elements (A-1), at second were abstractized by mkhris (A-2).




were abstractized by earth, water elements among 5 elements (A-1), at second were abstractized by

badgan (A-2).3. The solid betta state of membrane structures with high reduction potential, middle level of proton



were abstractized by wind element among 5 elements (A-1), at second were abstractized by rlung (A-

2).

Besides, the new conception "rlung, Mkhris, Badgan membrane - redoxy potentials 3 state line

system "allows the possibility to explain following general notions of TMTM in accordance to suggested

by us new conception:

1. General characteristics of rlung, Mkhris, Badgan as hot, cold, acute, stupid, motile, light

2. Division of Human Constitution specificity to Mkhris. rlung. Badgan

3. Classification of five solid organs in relation to

.

4. Classification of Diet factors in relation to

rlung. Mkhris. Badgan

5. Classification of Medicines in relation to



6. Seasonal changes of functional activity of Solid organs.

(increasing and decreasing)


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12

MEMBRANE - REDOXY POTENTIAL 3 STATE MECHANISM OF THEORY OF TRADITIONAL

MEDICINE ABOUT INTERRELATIONSHIP AND INTEROPPOSITION OF RLUNG, MKHRIS,

BADGAN

Picture 3

The intermediate gamma state of membrane structure with low redoxy potentials

The increase

of induction of

the action

potential

Decrease of

generation of

ATP, NADPH,

heat energy

from proton

gradients

The

intensification

of nerve

impulse

conduction

(conductivity)

The decrease

of ATP,

protein,

NADPH,

lipoproteid

synthesis

The low level

of thermo

genesis

Mobile Light Thin (narrow) Rough Cool

l.General characteristics of rlung, Mkhris. Badgan their unterrelation, interopposition andproperty of membrane-redoxy potentials 3 state line system.

According to theory of Traditional medicine the general characteristics of Mkhris, Badgan, Rlung

are as follows: "... Mkhris is characteristically hot, oily, acrid (acute-), light ... Badgan is

characteristically cool, oily, stupid, heavy ... Rlung is characteristically motile, unoilly, rough,

light

More quantity of unsaturated fatty acids (UFA) as main part of fluid alpha state of membrane

structures with high level of oxidation potential with high level of heat energy formation, middle intensity

of high energy phosphate - ATP generation, of high energy electrons - NADPH generation have T-

smelting + 15- + 18C i.e possessed the most "hot" property and easily undergoes to structural changes,

..."


13/103


13

coupling with formation of "thermogenic, protonophore phore" (Ya.Musil 1984) which are accompanied

by dispersion of many quantity "heat energy" (V.P.Skulacher 1972).

As regards to "acute" characteristic of Mkhris may be connected with very high reactivity of UFA (oc-

state) of membrane structures (Yu.A.Vladimirov et all 1972). Addition of "one unsaturated bind" leads to

11-fold increase of "coefficient of reactivity", while 4-6 unsaturated binds resulted to 1739-3478 fold

increase of reactivity (A.N.Detsina et all 1990, V.N.Ushkalova 1986). In close connection with this in

solid organs, where predominated a-state ofmembrane-redoxy potentials 3 state line system extent of

damage and disturbances of membrane structures following the onset of disease proceeds in more

intensive range (Ya.A.Vladimirov et all 1972) while (3-state of MS (badgan) showed slow reactivity

(Ya.M.lopukhin et all 1983), which coincided with "stupid" characteristic of "Badgan".

In such way in framework of the new conception we are explaining that "hot", "acute", "oily"

characteristics of "Mkhris" has connected with "thermogenic", "protonophore". "activatining"

The gamma state of membrane structure with low redoxy potentials

action of a-

state (unsaturated fatty acids) of MS

MEMBRANE REDOXY POTENTIAL 3 STATE MECHANISM OF APPEARANCE OF THEORY

OF TRADITIONAL MEDICINE ABOUT INTERRELATIONSHIP AND INTEROPPOSITION OF

RLUNG, MKHRIS, BADGANPicture 4

The increase

of induction of

the action

potential

Decrease of

generation of

ATP, NADPH,

heat energy

from proton

gradients

The

intensification

of nerve

impulse

conduction

(conductivity)

The decrease

of ATP,

protein,

NADPH,

lipoproteid

synthesis

The low level of

thermo genesis

Mobile Light Thin (narrow) Rough Cool

The fluid alpha state of Membrane structure with high oxy potentialsTheprevalence of

unsaturated fatty

acids in MS

(cisconfiguration)

which easily

subjected to

melting

The high

thermogenic

activity by

uncoupling

mechanism

O/P

The

intensification

of activity of

membrane

binding

enzymes and

receptors

The increase of activity of

adrenoreceptors and reception

activity of action of Medicaments

hormones, external factors

Hot-oily Hot Light Acute

The solid betta state of membrane structure with high red potentials

The prevalence

of saturated

fatty acids in

MS (trans-

configuration),

which easily

subjected to

freezing

The limitation

of thermo

genesis by O/P

mechanism

The decrease

of activity of

membrane

binding

enzymes,

receptors and

the increase of

ATP-synthesis

The decrease

of reception

activity of

action of

Medicaments,

hormones

external

factors

The increase of

activity of

cholinoreceptors

and the decrease

of cholinesterase

activity

Cool-oily Cold Heavy, strong Stupid Mucous (mucus)


14/103


14

While "cold", "heavy", "stupid" characteristics of "Badgan" has coincided with "energy accumulating",

heat limiting, "stabilizing" effects of (betta - state - saturated fatty acids) of MS i.e solid betta - state of

membrane structures with high level of reduction potential with high middle level of heat energy

formation, high intensity of high energy phosphate - ATP generation, of high energy electrons -

NADPH generation, containing more quantity of cholesterol, and saturated fatty acids (SFA), which

according to our new suggestion conditioned the abstraction notion "Badgan" also possessed "cold"

property, having T-of smelting + 53 - + 69C (Ua.Kagava 1985, U.Strier 1984).

Apart from this solid betta - state of membrane structures with high level of reduction potential with

high middle level of heat energy formation, high intensity of high energy phosphate - ATP generation,

of high energy electrons - NADPH generation (cholesterol, and SFA) possessed more resistence to action

of various "protonophore" factors (Yu.M.Lopukhin et all 1983, G.I.Klebanov et all 1986), which is

conditioned less thermogenic activity (V.P.Skulachev 1971) and resulted to limitation of thermogenesis.

Also, "motile", "light" characteristics of rlung are due to nerve impulse generating and impulse

conducting activity of intermediate gamma state of membrane structures with low level of oxidation-

reduction potential of excitable membranes (excitable cells), which for their normal functioning are

required a high level of proton gradient generation, high level of intensity of high energy phosphate -

ATP generation, high level of high energy electrons - NADPH generation, but the intermediate gammastate of membrane structures with low level of oxidation-reduction potential can not provide this in the

sufficient level.

In case of shortage of proton gradient generation and deficiency of high energy phosphate - ATP

generation, high level of high energy electrons - NADPH generation, which more easily provocated when

dominated the intermediate gamma state of membrane structures with low level of oxidation-reduction

potential are resulted to appearance of "motile", "light" characteristics, coded by abstract rlung thermin.

At normal condition, basic 3 states of MS existed in mutual transition and mutual oppression which

connected with theory of TMTM about interrelation-interposition property of rlung, Mkhris, Badgan.

Theory of Mongolian traditional medicine considered that ". . . cool character of Badgan decreases hot

character of Mkhris . . , Hot-oilness of Mkhris prevents excessively increase of cold (cool)-oilness of

Badgan i.e Mkhris and Badgan existed in interrelations and interopposition ... ".


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15

THE BASIC PERIOD OF APPEARENCE OF THE THEORY OF FIVE ELEMENTS AND THEORY

OF RLUNG, MKHRIS, BADGAN, YANG-YIN

Picture 5

By our opinion, above mentioned theoretical expression of Traditional Medicine had been appeared in the

result of reflection "transitional processes", which take place as follows :

1. The intermediate gamma state of membrane structures with low level of oxidation - reduction

potential with low level of proton gradient generation, low level of heat energy formation, low intensity

of high energy phosphate - ATP generation, low intensity of of high energy electrons - NADPH

generation supressed the excess prevalence of solid betta - state of membrane structures with high level

of reduction potential with middle level of heat energy formation, high intensity of high energy

phosphate-ATP generation, of high energy electrons-NADPH generation.

2. The fluid - alpha state of membrane structures with high level of oxidation potential with high level

of heat energy formation,middle intensity of high energy phosphate-ATP generation, of high energy

electrons - NADPH generation supressed the excess prevalence of solid betta -state of membrane

structures with high level of reduction potential with middle level of heat energy formation, high

intensity of high energy phosphate - ATP generation, of high energy electrons - NADPH generation.

3. The solid betta - state of membrane structures with high level of reduction potential with middle levelof heat energy formation, high intensity of high energy phosphate - ATP generation, of high energy

electrons - NADPH generation supressed the excess prevalence of the fluid alpha state of membrane

structures with high level of oxidation potential with high level of heat energy formation, middle intensity

of high energy phosphate - ATP generation, of high energy electrons - NADPH generation.

4. The intermediate gamma state of membrane structures with low level of oxidation-reduction potential

with low level of proton gradient generation, low level of heat energy formation, low intensity of high

energy phosphate - ATP generation, low intensity of of high energy electrons - NADPH generation

supressed the excess prevalence of the fluid - alpha state of membrane structures with high level of

THE

SUBSTAN

EXTERN

AL SIGNS

ABSTRACTI

ON

The three states of

MS with 3 state of

redoxypotentials

Substance

Fire, water, earth,

rlung, space, wood,

iron elements

The step of cognition by the

direct sensation

The step of abstract

cognition

Hot

Acute

Heav

Light

Fluid

Motile

Stupid

Cold

Hot

Acute

Fluid

Cold

Heavy

Stupid

UnoillyLi

g

Motile

}

}

}

}

Fire

element

Water

element

Earth

element

Rlung

element

}

}

}

Mkhris

(yang)

Badgan

(yin)

Rlung


16/103


16

oxidation potential with high level of heat energy formation, middle intensity of high energy phosphate -

ATP generation, of high energy electrons - NADPH generation

5. The fluid - alpha state of membrane structures with high level of oxidation potential with high level of

heat energy formation, middle intensity of high energy phosphate - ATP generation, of high energy

electrons - NADPH generation supressed the excess prevalence of the intermediate gamma state of

membrane structures with low level of oxidation - reduction potential with low level of proton gradient

generation, low level of heat energy formation, low intensity of high energy phosphate - ATP

generation, low intensity of of high energy electrons - NADPH generation

6. The solid betta - state of membrane structures with high level of reduction potential with middle level

of heat energy formation, high intensity of high energy phosphate - ATP generation, of high energy

electrons - NADPH generation supressed the excess prevalence of the intermediate gamma state of

membrane structures with low level of oxidation - reduction potential with low level of proton gradient

generation, low level of heat energy formation, low intensity of high energy phosphate - ATP generation,

low intensity of of high energy electrons - NADPH generation

Besides this, the solid betta - state of membrane structures with high level of reduction potential with

middle level of heat energy formation, high intensity of high energy phosphate - ATP generation, of high

energy electrons - NADPH generation served the role of precondition of normal existence and normalformation and reformation of the intermediate gamma state of membrane structures with low level of

oxidation-reduction potential with low level of proton gradient generation, low level of heat energy

formation, low intensity of high energy phosphate - ATP generation, low intensity of of high energy

electrons - NADPH generation, meanwhile the fluid - alpha state of membrane structures with high

level of oxidation potential with high level of heat energy formation, middle intensity of high energy

phosphate - ATP generation, of high energy electrons - NADPH generation served the role of

precondition of normal existence and normal formation and reformation of the intermediate gamma state

of membrane structures with low level of oxidation - reduction potential with low level of proton

gradient generation, low level of heat energy formation, low intensity of high energy electrons - NADPH

generation.

The fluid - alpha state of membrane structures with high level of oxidation potential with high level of

heat energy formation, middle intensity of high energy phosphate - ATP generation, of high energy

electrons - NADPH generation served the role of precondition of normal existence and normal formation

and reformation of thesolid betta - state of membrane structures with high level of reduction potential

with middle level of heat energy formation, high intensity of high energy phosphate - ATP generation,

of high energy electrons - NADPH generation i.e in favour of this suggestion recently has been

established that unsaturated fatty acids of alpha state (fluidity) of membrane structures prevents excessive

increase of saturated fatty acids of betta state of MS (solid), while betta state of MS (solid) decreases and

maintaines the normal alpha - state of MS /L.Strier 1985, E.Kreps 1981, Ya,Kagava 1985/ (Picture N 4)

One simple example of such processes is addition of one unsaturated bind of a-state of MS to p-state of

MS accompanied with decrease of T of smelting from + 39.5-to + 14C, which may be serve as one ofthe proofs of Traditional medicine's conception: ". . . hot of Mkhris decreases cold of Badgan. . . "

(Picture N 4).

2. Whole organism's regulatory function of Rlung. Mkhris. Badgan. their thermodinamical basis and

participation of membrane-redoxy potentials 3 state line system.

In old sutars of Traditional medicine it was stressed that ". . . If mkhris existed in adequate equal forms,

which forms the "heat energy" of organism, it provides the nutrition and substrates, necessary to function

of all organism ... If badgan is existed in equal balanced state, which adds the weight and fat, protects the

losses of nutrient substrates, ensuring the longevity of life . . . ".


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17

In basis of theory of Traditional Medicine we came to conclusion, that such formulation on whole

organism's regulatory function of rlung, mkris, badgan is closely connected with thermodynamical

process, which constantly takes place within living organism (M.Ambaga, B.Sarantsetseg 1990),

including membrane-redoxy potentials 3 state line system.

Fluidity alpha state of membrane structures with high level of oxidation potential with high level of heat

energy formation, middle intensity of high energy phosphate - ATP generation, of high energy electrons -

NADPH generation, having more cis - configuration (L.Strier 1985) is created unorderly thermodynamic

state, in same system of MS (E.A.Borodin et all 1981, 1985) unavoidly increased the probability of

transition all usefull energy (U) to useless unreversible heat energy (Q) with more lossess of free energy

(F).

In such way, in thermodynamical system, where is prevailed alpha state of membrane structures with high

oxidation potential of membrane-redoxy potentials 3 state line system, when created the condition of

transferring of proton gradient to heat energy, not to generation of of high energy phosphate - ATP, of

high energy electrons - NADPH "thermodynamic process is going in direction to more losses of useful

free energy (F), and to more dispersion of useless "heat" energy (Q) i.e thermodynamic process of

transition F-TS is directed to decrease of F, and gradually increase of Q, TS, which probably may serve

the guidelines of right interpretation of theory of Traditional medicine "... mkhris forms "heat" andprovides the necessary energy to normal function of organism . . . But excessively increase of mkhris

burnes the all the energy and the nutritients of all organism . . . ".

While betta state of membrane structures with high reduction potential of organism creates more stabile

"thermodynamic" system, in such system due to trans - configuration of saturated fatty acids and

cholesterol (L.Strier 1985), when created the condition of transferring of proton gradient not to heat

energy, to generation of of high energy phosphate - ATP, of high energy electrons - NADPH,

thermodynamic processes accompanied with more reservation of free energy (F) and less dispersion of

heat (Q, TS) energy i.e thermodynamic reaction proceeds in direction: to gradually increase of F, and to

decrease of Q, which are expressed in Traditional Medicine as ". . . Badgan addes the weight of organism,

protectes the nutrient from burning and gives possibility to long life ... ".

As regads to intermediate gamma state, when created the condition of less generation of proton gradient,

thereby formation of heat energy, and generation of high energy phosphate -ATP, of high energy

electrons - NADPH became diminished "which by our openion, conditioned the all external patterns of

rlung abstract theoretical expression is unstable "thermodynamic system" where "thermodynamic reaction

is proceeded in minimum level of free energy /F/ and maximum level of enthropy /TS/ ".

Apart from this there can be reasons to say that theory of MTM on whole organism's regulatiory role of

"rlung, Mkhris, Badgan" has close connection with action of symphatic /SNS/ and parasymphatic /PNS/

nervous system, because of recruitment the fluid state of MS with high oxidation potential created

precondition of activation of SNS, while recruitment betta - state of MS with high reduction potential and

high viscosity created precondition of activation of PNS, while formation of betta - state of MS leads to

activation of PNS, external signs of which has more similarity with appearance of cold, stupid, heavymucus characteristics Badgan /M.Ambaga 1991/.


18/103


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Picture 6

We, by using the new methodological approach Substance external properties abstraction, taking in

attention the such principle that . . . five elements such as fire, water, earth, rlung, are not the really

existed elements . . . five elements are abstracted symbols, which appeared in order to make easy to

understand to people and in the result of perceiving the following external forms, colours . . . came to

conclusion that:

The comparative theoretical analysis of philosophical basis of fiveelements theory of Oriental

Medicine

In connection with this principle that theory of five elements of Oriental medicine expressed by thermins

as fire, water , earth , rlung, cosmos, wood iron had been formed as abstracted, not really

existing elements, it would be more interesting, if clarify these following guestions:

When, how had appeared the theory of five elements in the result of revealing which thing and

identifying it with what thihgs.

In appearing the theory of five elements what thing had been played the role of material, really

substance, existing in side of human body.

1. The theory of five elements in Oriental medicine had formed in the basis of common philosophical

views i.e. it had differentiated each other by that, what thermins had been used, and had not differentiated

what thing to be symbolized, abstracted.

2. Between five elements theory Traditional Medicine did not existed such sharp differences, butamong researchers existed many controversial views in this regard.

3. The reason, why in Oriental Chinese medicine used thermins as "wood", "iron" and in Traditional

medicine used such thermins as "water", "rlung", "fire" may be explained by this circumstances, that

thinkers of this time had resort to identify own recognized things with such things, with which had been

encountered (faced with) in every day life.

By using the methodological approach and new conception as "substance - external properties -

abstraction", "rlung, Mkhris, Badgan abstract thermin - membrane - redoxy potentials 3 state line system

"we are managed to reveal that the role of "material substance" leading to appearance of abstracted five

elements theory in Oriental Medicine and which had been secretly existed behind such external signs-

T

The occurrence of solidization and

fluidization process in MSF - the melting fluid alpha state of

MS (K-III)

F+S-the intermediate gamma state(M-D)

S-Solid betta state (D-L)

Q-L, L-1, L-2- the boundary of

transforming the fluid alpha state tosolid betta state.

L-Q, Q1, Q2 -the boundary of

transforming the solid betta state tofluid alpha state

Q-the point of fluidization of MS

L-the point of solidization in MSM-the alpha part of gamma - state of

MS

40

30

20

10

F

F+S

S

Unsaturated Saturated

Fatty acids ratio (%)

Q-2

Q-1

Q

M

K

D

L

L-1

L-2


19/103


19

patterns as: hot, cold, cool, sharp, fullness, emptiness, activated, slow, dampness may be played the

membrane-redoxy potentials 3 state line system of human body and their 3 basic states: fluid alpha state

of membrane structures with high oxidation potential, solid betta state of membrane structures with high

reduction potential, gamma state of membrane structures with slow redoxy potentials i.e. behind hot,

sharp, acrid, activated external properties of abstracted elements "fire", "wood" had existed the

thermogenic, "enzyme-receptor" activated fluid alpha state with high oxidation potential, belonging to

membrane-redoxy potentials 3 state line system, while, behind cold, cool, heavy, passive, slow, dampness

external signs of abstracted elements "water", "earth", "wood" had been existed the ATP - syntethizing

energyaccumulating, thermolimited solid betta state with high reduction potential belonging to

membrane-redoxy potentials 3 state line system of human body (Picture N 5).

To questions of explaining the identity and difference of theory Yang-Yin and theory rlung.

Mkhris. Badgan in the framework of new conception "rlung. Mkhris, Badgan membrane -

redoxy potentials 3 state line system "

During comparative theoretical investigation, which has been conducted by using the new methodological

approach "External patterns - theory of five elements", "Substance - external patterns - abstraction" we

came to conclusion that the theory of Yang - Yin and the theory of rlung, Mkhris, Badgan in Mongolianand Korean Traditional Medicine had formed in the result of converting the theory of five elements to

specific object of thinking i.e. theory of five elements and theory Yang -Yin, rlung - Mkhris, Badgan are

two unseparately steps of recognition of one things-one substance. The this our conclusion has been

confirmed by theoretical expressions, written in the "The yellow emperor's classic of Medicine" (1995)

as, ". . . The elements of fire and water are categorized into yang and yin, the fire being yang and the

water being yin".

Also, we had revealed such close relationship, which can be expressed as: Yang-Mkhris- fluid alpha state

of membrane structures with high oxidation potential, Yin Badgan - solid betta state of membrane

structures with high reduction potential.

In order to confirm this close relationship we are drawing the below evidence:

A.Theoretical expression on whole organism's regulatory role of Yang-Yin and rlung. Mkhris.

Badgan and their membrane - redoxy potentials 3 state line system.

What about membrane mechanism and thermodynamic equivalents of theoretical expressions of KMTM

on the whole organisms regulatory role of Yang - Yin, and rlung, Mkhris, badgan we are concluded that

the prevalence of fluid alpha state of membrane structures with high oxidation potential in

energysynthetizing membrane structure leads to increase of bind energy - enthropy /TS/, decrease of free

energy /F/ by O/ P mechanism (oxydation : phosphorylation), accompanying with more heat energy

equivalents

The whole organisms regulatory role of Yang, Yin and Mkhris, Badgan had expressed in theory of

CKTM (The yellow emperor's classic of medicine, 1995), as: ". . . energy requirement of human body

compensated by increasing of Yang, while energy preservation had ensured by increasing of Yin. . .Yang

is the energy, the vital force, the potential, while yin is the substance, the foundation, the mother that

gives rise to all this potential. . . ", in theory of MTM as: ". . . If Mkhris existed in equal forms, which

forms the "heat" of human body, provides the energy, nutrition and substrates, necessary to function of all

organism ... If badgan is existed in equal state, which adds the weight and fat, protects the losses of

substrates, ensuring the longevity of life. . . " i.e. it was became appearant that the theoretical expression

of MKTM on the whole organisms regulatory role of Yang - Yin and Mkhris, Badgan had moresimilarity, in otherwise, by abstract thermins of Yang, Mkhris in MKTM considered the situation, how in

human body has been occurred the process of energy consumption, while by abstract notion of Yin, and

Badgan in MKTM has been showed the general feature of energy preservation process inside of human

body.


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20

formation and external signs of these above mentioned membrane based process summarized in the

theory of KMTM as "hot", "sharp", "activating" external properties of Yang, Mkhris and as increase of

Yang, Mkhris hot, thi decreaie of Yin, Badgan cool and increase of body heat.

In other case, the predominance of solid betta state of membrane structures with high reduction

potential in the energy - synthetizing membrane structure of human body, associated with excessive

formation of free energy - ATP and less formation of bind, heat energy /TS/, and this membrane based

process conditioned the more energy preservation and limitation of heat energy formation, which may be

expressed in the theory of KMTM as increase of Yin cold and Badgan cool characteristics.

The results of all above mentioned theoretical comparative analysis has been showed that the membrane

redoxy mechanism of theory of KMTM on whole organism's regulatory role of Yang -Yin, rlung,

Badgan, Mkhris can be explained by following close relationship as: "Yang, Mkhris - fluid, alpha state of

MS with high oxidation potential - decrease of ATP synthesis - increase of heat energy formation -

decrease of energypreservation - appearance of "hot", "sharp" external patterns of Yang, Mkhris", and

"Badgan, Yin - solid betta state of membrane structure with high reduction potential - increase of ATP

synthesis - increase of energy preservation decrease of energy losses and thermogenesis - appearance of

"cold", "cool" external patterns of Yin, Badgan" and so the first way of increase of solid betta - state of all

membrane structures with high reduction potential in winter gives the possibility to discover the matte rof theory of Traditional Medicine ". . . in winter, under action of cold badgan to be stored, but concealed

by cold.. . " (BJigmed 1988).

The second way of increase of betta state of membrane structure with high reduction potential directly

connected with the thermin of Traditional medicine ". . . warmth of the sun in spring causes "Badgan" to

arise . . ".

But if excessively increase of betta - state (trans - configuration) in spring potentiated by low temperature

and saturated fatty acids, cholesterol (Y.A.Vladimirov 1983) leads to "cold - depending phasic transition

of membranes with high reduction potential" with following abruptly losses of activity of membrane

binding enzymes and receptors (M.E.Kreps 1981), which had expressed in MTM by following notion: ". .

. if in spring heavy and oily qualities combined with coolness stored, arises "Badgan" ailment . . .".

And so measurements of prevention from disease due to "cold-depending phasic transition" must be

directed to establishment of proper membrane states by rationale use of foods and clothes in spring and

autumn.

B.The similarity og theoretical expressions of KMTM on general characteristics of Yang-Yin and rlung.

Mkhris. Badgan and membrane structures.

During our comparative investigation we had revealed that hot, sharp, hot-oil, fullness, activated, light

external characteristics of Yang-Mkhris are closely connected with hot, sharp, hot oil, fullness, activated,

light external properties of abstracted elements "fire", "wood", and behind such general characteristics of

Yang, Mkhris, abstracted elements "fire", "wood" had existed the process of intensification of heat energy

formation and activation of "enzyme - substrates", "hormone-receptor" interaction, which had been

carried out in the background of predominating the fluid-alpha state of membrane structure with highoxidation potential .

Also, it can be say that "cold", "cool", "passive", "slow", "dampness" general properties of Yin, Badgan

had existed in close relationship with "cold", "cool", "passive", "slow", "dampness" general

characteristics of abstracted elements "water", "earth", "iron", the molecular, membrane mechanism of

appearance of such general characteristics of Yang, Badgan and abstracted elements "water", "earth",

"iron" would be explained by activation of ATP-energy synthesis, energy accumulation limitation of heat

energy formation and inhibition of activity of membrane binding enzymes and receptors, owing to

prevailing of solid betta state of membrane structures with high reduction potential (Picture N5).


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21

In such way the results of our comparative investigation allows to conclude that theoretical expressions of

KMTM on external signs of Yang - Yin and Mkhris, Badgan did not distinguished by philosophical basis

and inner substance level i.e. the unique role of inner substance in regarding lo externally distinguished

general characteristics of Yang-Yin, Mkhris - Badgau played the solid betta state of membrane

structures with high reduction potential and offluid alpha state of membrane structures with high

oxidation potential.

The appearance of such pathological signs: as high temperature, thirst, acute intensive pain, acute attacks

of disease during excessive pathological increase of general characteristics of Yang, Mkhris are

associated with intensive release of pyrogenic prostaglandin Fl, presentation of "antigen" in the

membrane surface of macrophages and lymphocytes, activation "antigen-antibody" interaction and

release of many inflammation mediators in background of excessive increase of fluid alpha state of

membrane structures with high oxidation potential.While decrease of Body heat, feeling of cold, slow

indigestion, more sleeping , chronic duration of disease which had been observed during excessivepathological increase of general characteristics of Badgan, Yin are explained by inhibition of heat energy

formation /by O/P mechanism/, chronic shortage of heat energy, decrease of H+-gcneration and HCL-

synthesis , inactivation of "antigen" presentation on macrophage membrane structure

anddecrease of-excitability of excitable membranes in the background of solid betta state of membrane

structures with high reduction potential.

G General characteristics of human body

regulation,when established the normal status

coded by abstract Mkhris thermin



coded by abstract Yang thermin

Mkhris Yan 1.Hot l. Hot

2.Sharp 2. Fullness3.Hot oily 3.Quickly4.Li ht 4. Hi h functionalactivit5.Bad smelling Ac6. ualit 5.Powerfull7.Moist 6.Li ht mobile

7.Positive8.Transparent

G General characteristics of human

body regulation, when established the

normal status coded by abstract Badgan



coded by abstract Yin thermin

Bad an Yinl.Cool l. Cold2.Heavy 2. Heavy3.Cool oil 3.Passive4.stupid 4.Low functional5. Gen tie a6. Firm 5.Slow7.Sticky 6.Negative

7. Sticky8.Dark


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A. Ge neral characteristics of human body

regulation, when established pathological

status coded by abstract Mkhris thermin

1. High temperature

2. Great thirst

3. Shooting pains

4. Quicly subjects to treatment

5. Yellowing of the Urine

6. Much vapor

7. Yellowing of tongue

8. Sees white objects as yellow

9. Fast pulse

10. Attaction to cold

11. Bitter taste in the mouth

Illness is strongest at noon

Ge gneral characteristics of human body

regulation, when established pathological status

coded by

abstract Yang thermin

1. High temperature

2. Thirst

3. S Sharp attack of disease

4. Feeling of heat

5. Darkening of urine

6. Attaction to cold

7. Talkativeness

8. Bitter taste in the mouth

9. Yellowing of tongue

10. Quicly undergoes to treatment

A. General characteristics of human bodyregulation, when established the pathological

status coded by abstract Badgan thermin

1. Diminishing of Bodily warmth

2. Inability to digest food

3. Bodily heaviness

4. Abundance of Saliva and Mucus

5. Much sleep, loss resistance to cold

6. Frequent chronisation of Disease

7. Poor appetite

8. Less odour and vapor of Urine

9. Attaction to warmth, wants hot place

10. Weak, slow pulse

11 Diarrhea

12. Pale tongue

Gen General characteristics of human bodyregulation, when Esta established the

pathological status coded by abstract

Badganthermin

1. Constant coldness of body

2. Cold feeling

3. Wants to hot place, food

4. Frequent urination

5. Loss resistance to cold

6. Loss of appetite

7. Physical and Mental heaviness

8. Weak digestion

9. Swelling of Body

10. Slow, weak pulse

The theory of Tibetan - Mongolian, Korean Traditional Medicine in regarding to healthy existing

condition of human body had more similarity i.e. in the theory of KTM this question is expressed as ". . .

precondition of healthy existing of human organism is preservation of normal balance between Yang andYin . . . ", in the theory of MTM as: " . . . precondition of healthy existing of human organism is equality

which established between rlung, mkhris, badgan . . . ". It can be say the membrane-redoxy mechanism

of above mentioned theoretical expression may be explained by establishing the normal balance between

three basic st at es as fluid alpha state of membrane structures with high level of oxidation potential

with high level of heat energy formation, middle intensity of high energy phosphate - ATP generation, of

high energy electrons - NADPH generation and solid betta - state of membrane structures with high level

of reduction potential with high middle level of heat energy formation, high intensity of high energy

phosphate - ATP generation, of high energy electrons - NADPH generation, as well as intermediate

The theory of Yang-Yin and rlung. Mkhris. Badgan in regarding to healthy existing of human body and

membrane-redoxy potentials 3 state line system.


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gamma state of membrane structures with low level of oxidation - reduction potential with low level of

proton gradient generation, low level of heat energy formation, low intensity of high energy phosphate

- ATP generation, low intensity of of high energy electrons - NADPH generation under various

unpleasant actions, environmental influence, resulting to gain useful adaptation reactions.

C.Theory of Yang-Yin and rlung, Mkhris, Badgan about reason, provocating the disease and

membrane-redoxy potentials 3 state line system

According to the theory of KTM ". . . Every disease has been provocated in the basis of disturbance of

balance between Yang and Yin . . . ", while according to theory of TMTM ". . . The reason of disease is

losses of balance (disbalance) between rlung, mkhris, badgan . . . ". The membrane mechanism of such

similarity of theoretical formulations of KMTM in regarding to main reason of disease is associated with

disturbance of balanced equality between basic three st ates as fluid -alpha state of membrane structures

with high level of oxidation potential with high level of heat energy formation, middle intensity of high

energy phosphate - ATP generation, of high energy electrons - NADPH generation, solid betta - state of

membrane structures with high level of reduction potential with high middle level of heat energy

formation, high intensity of high energy phosphate - ATP generation, of high energy electrons - NADPH

generation, intermediate gamma state of membrane structures with low level of oxidation - reduction

potential with low level of proton gradient generation, low level of heat energy formation, low intensityof high energy phosphate-ATP generation, low intensity of of high energy electrons - NADPH

generation under action of pathogenic environmental factors, which at last, leads to unability of human

organism to conduct the normal adaptive reaction.

Basing on above mentioned experimental data we came to conclusion that decrease of immune reaction

intensity in connection with prevalence of betta state of MS with high reduction potential on

The principle "Fullness and emptiness" of Korean-Chinese traditional medicine and membrane-

redoxy potentials 3 state line system

Two of eight diagnostic and Treatment principle of Korean Chinese Traditional Medicine are principle

"fullness and emptiness" (Shin. Min Kyu 1995).

It can be say that, the principle "fullness and emptiness" shows the intensity of response of human body to

pathogenic factors and to action of medicinal preparations. When in human organism prevails the

"emptiness" it is demonstrated the signs of slowing of response reaction to pathogenic factors and to

action of Medicinal preparations, while increase of "fullness" is accompanied with stimulating the over

response reactions.

During comparative investigation we are revealed that "fullness" of Korean Traditional Medicine

corresponds to "sharp" characteristic of Mkhris, while "emptiness" is existed in close relationship with

"stupid" characteristic of "Badgan", because according to theory of Tibetan Mongolian Traditional

Medicine the "sharp" characteristic of Mkhris leads to suddenly attack of disease, shooting pains in all

parts of a body, high sensitivity to pathogenic factors and fast end of disease, the "stupid" characteristic of

badgan is contributed to frequent chronisation of disease, slow response reaction to Medical treatment,

Disease often got hidden, atypical forms.

In the result of comparative analysis we have find such close relationship, which can describe as follows:

"fullness - sharp characteristic of Mkhris - fluid alpha state of membrane structures with high oxidationpotential of immunocytes, accompanied with over response reactions" "emptiness -stupid characteristics

of badgan - solid betta state of MS with high reduction potentials of immunocytes, accompanied with

suppressed response reactions". ur experimental data has been demonstrated that increase of solid betta

state of membrane structure with high reduction potential on immunocytes after administration of

cholesterol in dose 250 mg/kg in mices leads to decrease quantity of immunocytes in 1.27 fold, antibody

titer -1.38 fold, immunostimulator effects of medicinal preparations in 1.2-1.42 fold (P


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immunocytes leads to an appearance of external patterns, which in Korean traditional Medicine is

described under thermin "emptiness", in Mongolian traditional Medicine under thermin "stupid"

characteristic of badgan.

The intensification of immune reaction intensity is due to increase of fluid alpha state of MS with high

oxidation potential on immunocytes accompanied with appearance of some external patterns, which is

expressed in theory of KTM by thermin "fullness", in theory of Mongolian Traditional Medicine by

thermin "sharp" characteristics of Mkhris.

Our new suggestion /M.Ambaga, Kim Ki Chang 1996/ relating to close coincidence of "emptiness" and

"stupid" characteristics with "betta state of MS with high reduction potential -dependent immune

deficiency state" has confirmed by the results of investigation of other authors /Li Song Hyo 1991, Kim

Chang Gol 1991, Ching Tae Uong 1991, Rak Uong Hun 1991/ during which they had established that the

appearance of "emptiness" is connected with decrease of immunocytes and antibody synthesis, also

Rehmannice glutinosae Epimedium sagitatum, Glycyrrhiazae uralensis, which used for treatment of

"emptiness" - like disease had possessed the immunostimulator effects in the form of increasing the cell

- mediated and humoral immunity.

Such interpretation of principle "emptiness and fullness" gives us possibility to increase immune reaction

of a human body by using medicaments, which is used in traditional Medicine for converting emptiness tofullness, "stupid" characteristic of Badganto "sharp" characteristic of Mkhris.

The principle "exterior" and interior of Korean Traditional Medicine and membrane-redoxy

potentials 3 state line system.

Our studies have been showed that the principle "exterior and interior" of Korean - Chinese Traditional

Medicine corresponds to philosophic category "external patterns and inner essence". If considered the

principle "exterior and interior" in accordance with new conception "Substance - external patterns -

abstract notion " proposed by professor M.Ambaga (1994) the principle "interior" corresponds to

substances-inner material secretive objects, while "exterior" is connected with external properties of

Ying, Yin. Judging by theory of Korean-Chinese Traditional Medicine in majority case exterior and

interior had identical origin i.e. interior hot-exterior hot, interior cold-exterior cold, in this case

establishment of right Diagnosis is very easy. But there are such cases, when exterior is not

corresponded to interior, in this case establishment of right Diagnosis would become more difficulty

/Kim Ki Chang 1996/.

We are attempted to explain the scientific essence of accordance and unaccordance of "interior" and

"exterior" In Korean Traditional Medicine by using the new conception "Substance External patterns-

Abstract notion" and "rlung, Mkhris, Badgan abstract theory and membrane-redoxy potentials 3 state

line system.

"In the result of conducting the comparative analysis we are revealed that the principle of accordance of

exterior with interior corresponds to this situation, when external patterns of human normal existence and

disease are coincided with to this process, which are initiated (occurred) in membrane-redoxy potentials

3 state line system level (3 morpho-functional states of MS) i.e. hot, sharp, light characteristics "Mkhris"and alpha state of MS with high oxidation potential. But there are situations when external characteristics

- outwardly manifested signs of mkhris, badgan and Yin, Yang did not corresponded to this process,

which is inwardly initiated in membrane-redoxy potentials 3 state line system

Such scientific interpretation of "Exterior and Interior" principle of Korean Traditional Medicine shows

that in case of appearance of unaccordance of "Exterior and Interior", the medical treatment should be

directed to correct of Disturbances, occurred in basic morpho-functional states of

level i.e. externally hot,

light, sharp characteristics of Mkhris and internally solid betta state of MS with high reduction

potential. Such uncorrespondance of external patterns with inner substances are described in Korean

Traditional Medicine as exterior cold-interior hot, Exterior hot-Interior cold.

membrane-redoxy


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potentials 3 state line system. Classification of five solid organs in relation to rlung, Mkhris,Badgan

and their membrane-redoxy potentials 3 state line system specifics.

According to theory of MTM ". . . solid organ liver-is the Mkhris dominated organ, because it locates in

the residence of general Mkhris becoming the path of movement of normal and form changed Mkhris.

Results of our comparative investigation has been showed, that in membrane-redoxy potentials 3 state

line system of liver is accumulated the products of FROL more intensively under direct action of high

temperature (37C, 47C, 57C, 67C, 77C, 87C,) than other solid organs (4.2-7.5 fold P


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Replaccmanl of alpha-state of MS of liver cells by

Documents

NCM MEDICINE