Nodular fasciitis 1

Nodular fasciitis

Nodular fasciitisClassification and external resources

Micrograph of nodular fasciitis showing the haphazard arrangement of cells (tissue culture-like pattern). H&E stain.

ICD-10 M72.4 [1]

ICD-9 728.79 [2]

Nodular fasciitis, also known as nodular pseudosarcomatous fasciits, pseudosarcomatous fasciitis, andsubcutaneous pseudosarcomatous fibromatosis,[]:992 is a benign soft tissue lesion most commonly found in thesuperficial fascia. The lesion commonly occurs in the first three decades of life. Upper extremities and trunk are themost common affected anatomical sites. Previous history of trauma may be present. Clinically and histologically,nodular fasciitis may be mistaken for a sarcoma.

Etiology and clinical courseUntil recently, nodular fasciitis have been considered a reactive process of uncertain etiology.[3] However, recentfindings indicate that nodular fasciitis is a self-limited clonal neoplastic process (see below). Clinically, nodularfasciitis presents as a subcutaneous "growth" over a period of 3-6 weeks that eventually regresses. The lesion usuallyreaches a size of 2-3 cm. Larger lesions are unusual. Local recurrence has been described after simple surgicalexcision but it is rare.

Nodular fasciitis 2

Histology•• Histologically vast array of patterns.• Short S-shaped fascicles, inflammation, accelerated mitotic index with normal mitoses.•• Essentially spindle cell proliferation.•• Stroma is rich in collagen and/or myxoid ground substance.

Additional images

Low mag. Intermed. mag.

References[1] http:/ / apps. who. int/ classifications/ icd10/ browse/ 2010/ en#/ M72. 4[2] http:/ / www. icd9data. com/ getICD9Code. ashx?icd9=728. 79[3][3] Oliveira AM, Chou MM. USP6-induced neoplasms: the biologic spectrum of aneurysmal bone cyst and nodular fasciitis. Hum Pathol. 2013

Jun 11. doi:pii: S0046-8177(13)00116-0. 10.1016/j.humpath.2013.03.005. PubMed PMID: 23769422.

Article Sources and Contributors 3

Article Sources and ContributorsNodular fasciitis  Source: http://en.wikipedia.org/w/index.php?oldid=580007007  Contributors: Adavidb, Andreusp6, Arcadian, Bwpach, DarkArcher, Dortz, Edcolins, Gyre, Headbomb, MyCore Competency is Competency, Nephron, Oh Snap, Rich Farmbrough, Sadads, TheJJJunk, WhatamIdoing, Woohookitty, 6 ,55דוד anonymous edits

Image Sources, Licenses and ContributorsFile:Nodular_fasciitis_-_high_mag.jpg  Source: http://en.wikipedia.org/w/index.php?title=File:Nodular_fasciitis_-_high_mag.jpg  License: Creative Commons Attribution-Sharealike 3.0 Contributors: NephronImage:Nodular fasciitis - low mag.jpg  Source: http://en.wikipedia.org/w/index.php?title=File:Nodular_fasciitis_-_low_mag.jpg  License: Creative Commons Attribution-Sharealike 3.0 Contributors: NephronImage:Nodular fasciitis - intermed mag.jpg  Source: http://en.wikipedia.org/w/index.php?title=File:Nodular_fasciitis_-_intermed_mag.jpg  License: Creative Commons Attribution-Sharealike3.0  Contributors: Nephron

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