ASSOCIATION FOR ACADEMIC SURGERY AND SOCIETY OF UNIVERSITY SURGEONS—ABSTRACTS196

8.17. IsThyroidectomy inPatientsWithHashimoto’s Thyroid-itis More Risky? C. M. McManus, J. Luo, R. Sippel, H. Chen;University of Wisconsin, Madison, WI

8.18. TheNatural Flavinoid, Chrysin, in the Treatment ofMed-ullary Thyroid Cancer. B. Zarebczan, M. Kunnimalaiyaan, H.Chen; University of Wisconsin, Madison, WI

8.19. Evidence of a Stabilizing Mutation of-Catenin Encodedby CTNNB1 Exon 3 in a Large Series of Sporadic Para-thyroid Adenomas. L. F. Starker,1,2 A. Fonseca,1 G.Akerstrom,2 P. Bjorklund,2 G. Westin,2 T. Carling1; 1YaleUniversity School of Medicine, New Haven, CT; 2UppsalaUniversity Department of Surgical Sciences, Uppsala, Uppsala

8.20. Down-Regulation of Notch1 Expression in PapillaryThyroid Carcinoma Correlates With Advanced Age andTumor Aggressiveness. X. Yu, H. Chen, R. S. Sippel;University of Wisconsin School of Medicine and PublicHealth, Madison, WI

PEDIATRICS AND DEVELOPMENTALBIOLOGY 1: MECHANISMS & MODELS

9.1. Inhibition of Focal Adhesion Kinase (FAK) Leads to De-creased Cell Survival in Malignant Renal Rhabdoid Tu-mor Cells. M. Megison, L. Gillory, J. E. Stewart, H. Nabers,E. A. Beierle; University of Alabama - Birmingham,Birmingham, AL

9.2. Genetically Engineered Herpes Simplex Virus Express-ing IL-12 Suppresses Murine Neuroblastoma TumorGrowth. L. A. Gillory,1 M. C. Haas,2 G. K. Friedman,2 M. L.Megison,1 J. E. Stewart,1 J. N. Parker,4 J. M. Markert,3 G. Y.Gillespie,6 E. A. Beierle5; 1University of Alabama -Birmingham, Birmingham, AL; 2Department of Pediatrics,Children’s Hospital of Alabama, University of Alabama atBirmingham, Birmingham, AL; 3Division of Neurosurgery,Children’s Hospital of Alabama and University of Alabama atBirmingham, Birmingham, AL; 4Department of Pediatrics,Children’s Hospital of Alabama and University of Alabama atBirmingham, Birmingham, AL; 5Department of Surgery,Division of Pediatric Surgery, University of Alabama atBirmingham, Birmingham, AL; 6Division of Neurosurgery,University of Alabama at Birmingham, Birmingham, AL

9.3. Notch1 Signaling in Neuroblastoma. J. F. Burke,1,2 Q.Khan,1 S. Kunnimalaiyaan,1 M. Roy,1 M. Kunnimalaiyaan1;1Endocrine Surgery Research Laboratory, Department ofSurgery, University of Wisconsin–Madison, Madison, WI;2Department of General Surgery, University ofWisconsin–Madison, Madison, WI

9.4. Single Lgr5+ Intestinal Stem Cells Co-Cultured With In-testinal Subepithelial Myofibroblasts (ISEMF) Differenti-ate into Absorptive and Secretory Cell Lineages WithoutExogenous Growth Factors. E. R. Barthel, X. Hou, J. A.Matthews, A. L. Speer, F. G. Sala, T. C. Grikscheit; Children’sHospital Los Angeles, Los Angeles, CA

9.5. Withdrawn

9.6. Formation of Intestinal Atresias in the Fgfr2IIIb-/- MouseModel is not Associated with Defects in NotochordDevelopment or Alterations in SHH Expression. A. L.Reeder, R. A. Botham, M. Franco, K. Zaremba, P. F. Nichol;University of Wisconsin School of Medicine and Public Health,Madison, WI

9.7. Selective Laser Photocoagulation Manipulates BloodFlow Dynamics in Microcirculation. G. S. Lee,1 R. M.Webber,5 M. Lin,1 D. C. Simpson,1 B. C. Gibney,1 N.Filipovic,2,4 A. Tsuda,2 M. A. Konerding,3 S. J. Mentzer1;1Brigham & Women’s Hospital, Boston, MA; 2Harvard Schoolof Public Health, Boston, MA; 3Johannes Gutenberg University- Mainz, Mainz, Germany; 4University of Kragujevac,Kragujevac, Kragujevac; 5Harvard Medical School, Boston, MA

9.8. Reduction of Bioavailable Vascular Endothelial GrowthFactor (VEGF) Alters Terminal Differentiation of the Ab-sorptive andSecretoryLineages inNeonatalMouse Intes-tine. S. M. Norgaard,2 J. A. Matthews,1 X. Hou,1 F. G. Sala,1

A. L. Speer,1 E. R. Barthel,1 T. C. Grikscheit1; 1ChildrensHospital Los Angeles, Los Angeles, CA; 2University ofSouthern California Keck School of Medicine, Los Angeles, CA

9.9. Pharmacokinetics and End Organ Effect of PDE5 Inhibi-tors in the Fetal Lamb Model of Congenital Diaphrag-matic Hernia. E. H. Shue,1,2 S. Schecter,1,2 W. Ferrier,2 D. N.Miniati1,2; 1University of California - San Francisco, SanFrancisco, CA; 2University of California Davis Medical Center,Sacramento, CA

9.10. Human Cholangiocyte Susceptibility to Infection WithRotavirus -Parallels to theMurineModel of BiliaryAtre-sia.A. C. Coots,1 B. M. Donnelly,1 S. K. Mohanty,1 M.McNeal,1

K. Sestak,2 G. M. Tiao1; 1Cincinnati Children’s HospitalMedical Center, Cincinnati, OH; 2Tulane National PrimateResearch Center, Covington, LA

9.11. A Multi-scale Agent-based Model of Necrotizing Entero-colitis Integrating Oxidative Stress, Inflammation, andMicrovascular Thrombosis. M. Kim, S. Christley, J.Alverdy, D. Liu, G. An; University of Chicago, Chicago, IL

9.12. Site-specific Impaired Mucosal Immunity in the MurineNeural Crest-Specific Deletion of Endothelin Receptor-B Model of Hirschsprung’s Disease. A. Gosain, A.Heneghan, J. Pierre, A. Gosain; University of WisconsinSchool of Medicine and Public Health - Department ofSurgery, Madison, WI

9.13. Diverse Early Intestinal Microbiota as a ContributingFactor in Necrotizing Enterocolitis. M. L. Williams, H. O.Humes, A. J. Fried, B. B. Bell, S. Castle, A. Grishin, H. R.Ford; Childrens Hospital Los Angeles, Los Angeles, CA