1
S128 Poster presentations, Thursday 18 September 2014/European Geriatric Medicine 5S1 (2014) S83S158 Mean gait speed changed from 0.33 m/s (baseline) to 0.39 m/s (p = 0.047), from 0.29 m/s to 0.42 m/s (p = 0.024), and from 0.34 m/s to 0.36 m/s (p = 0.450) whereas mean grip strength changed from 4 kg (baseline) to 5 kg (p = 0.180), from 5.17 kg to 12.17 kg (p = 0.027) and from 2.6 kg to 2.2 kg (p = 0.713) in groups A, B and C respectively. Mean frailty score changed from 5.0 to 3.0 (p=0.131), from 4.67 to 2.67 (p = 0.034), and from 4.4 to 4.0 (p = 0.157) in groups A, B and C respectively. Conclusion: Frail elderly must receive both nutritional as well as exercise intervention for the alleviation of their frail status. Exercise intervention in the form of nordic walking can be an attractive op- tion for significant functional improvement in frail older patients. P144 The association of frailty with serum 25-hydroxyvitamin D in older men L. de Buyser, M. Petrovic, Y.E. Taes, K. Toye, J.M. Kaufman, S. Goemaere Ghent University, Ghent, Belgium Introduction: The aim of this study was to determine the association of frailty with serum 25-hydroxyvitamin D in a population-based sample of older men. Methods: Cross-sectional analyses were performed on data from a longitudinal study in 264 ambulatory men aged 72 to 87 years and registered in the community of Merelbeke (Ghent, Belgium) in 1997. Frailty status (robust vs. prefrail or frail) was assessed using the Study of Osteoporotic Fractures (SOF) index with the components of weight loss, inability to rise from a chair 5 times without using arms, and reduced energy level. Serum 25-hydroxyvitamin D was determined after extraction by radioimmunoassay. Low 25- hydroxyvitamin D level was defined as <30 ng/ml. Logistic regression models adjusted for age and body mass index examined the relationship between (low) 25-hydroxyvitamin D level and (pre)frailty. Results: Mean age was 76.7±3.9 years. According to the SOF index, 181 men (69%) were robust, 79 men (30%) were prefrail or frail. Serum 25-hydroxyvitamin D concentration was significantly associated with (pre)frailty (OR per ng/ml decrease = 1.05, 95%CI = 1.01–1.09, P=0.009). Older men with low 25-hydroxyvitamin D levels had 2.7 times more odds of being (pre)frail than older men with normal 25-hydroxyvitamin D levels (OR = 2.71, 95% CI = 1.38– 5.40, P = 0.005). Key conclusions: Our findings suggest that lower serum 25- hydroxyvitamin D levels are associated with (pre)frailty in older men. P145 Nutrition plays a gender-dependent role in disability in an elderly Sardinian population D. Concu, G.M. Pes University of Sassari, Italy Introduction: In the elderly population the disability rate is lower in men than in women, although in the latter life expectancy in generally higher. In Sardinia island a remarkable gender equality in mortality has been reported (Poulain et al., 2004), but it is not known if this also holds true for disability. We evaluated the disability level in a sample of elderly subjects and correlated it with lifestyle and socio-demographic variables. Subjects and Methods: One-hundred subjects (50% men, aged 78–93) recruited in the island’s main cities. A comprehensive assessment was carried out in each participant: ADL, IADL, Barthel index, MMSE, Exton-Smith and Tinetti scale, km/wk and MNA. The association of predictors with disability was performed by multiple linear regression analysis. Results: Among women the strongest predictors of disability, as reflected by IADL, were MNA (p = 0.0001), SPMSQ (p = 0.004) and Tinetti score (p = 0.001), whereas in males physical activity expressed as km/wk (p = 0.039), the Exton-Smith score (p = 0.0001) and MMSE (p = 0.001) were the most important predictors. Conclusion: These results suggest that IADL disability in males is mostly linked to cognitive and motor impairment, whereas in women is influenced also by a concomitant malnutrition. We suggest that physical activity is a protective factor for disability in men, while women lacking this protective mechanism are more vulnerable to a nutritional deficiency. P146-1 Frailty and health-related quality of life in ambulatory older men L. de Buyser, M. Petrovic, Y.E. Taes, K. Toye, J.M. Kaufman, S. Goemaere Ghent University, Ghent, Belgium Introduction: The aim of this study was to investigate the relationship between frailty status and health-related quality of life in a population-based sample of ambulatory older men. Methods: Cross-sectional analyses were performed on data from a longitudinal study in 260 ambulatory men aged 72 to 87 years and registered in the community of Merelbeke (Ghent, Belgium) in 1997. Frailty status (robust, prefrail, frail) was assessed using the Study of Osteoporotic Fractures (SOF) index with the components of weight loss, inability to rise from a chair 5 times without using arms, and reduced energy level. Health-related quality of life was assessed using the eight domains of the Short Form-36 questionnaire. Subjects in the lowest quartile of the distribution were classified as having ‘poor’ status for each domain. Logistic regression models adjusted for age examined the relationship between frailty status and poor status on the Short Form-36 domains. Results: Mean age was 76.7±3.9 years. According to the SOF index, 181 men (69%) were robust, 69 men (26%) were prefrail, and 10 men (4%) were frail. The distribution of the Short Form-36 domain scores differed significantly across frailty statuses (Table 1). Prefrailty and frailty were significantly associated with increased prevalence of poor status for all 8 Short-Form 36 domains. Key conclusions: Our findings suggest that both prefrailty and frailty are associated with poorer health-related quality of life in older men, independent of age. Table 1. Scores on the Short Form-36 domains according to frailty status All (N = 260) Robust (N = 181) Prefrail (N = 69) Frail (N = 10) P a Median IQR Median IQR Median IQR Median IQR General Health Perception 65 55, 75 70 60, 80 60 46, 70 48 44, 60 <0.001 Physical Function 80 65, 75 90 75, 95 70 51, 80 38 19, 81 <0.001 Role Physical 100 50, 100 100 75, 100 75 0, 100 75 19, 100 <0.001 Bodily Pain 90 67, 100 90 69, 100 79 56, 100 55 44, 92 0.003 General Mental Health 82 72, 92 84 72, 96 76 60, 87 60 52, 70 <0.001 Role Emotional 100 67, 100 100 100, 100 100 33, 100 0 0, 100 <0.001 Vitality 75 65, 85 80 70, 90 65 51, 80 40 34, 58 <0.001 Social Function 100 88, 100 100 88, 100 88 63, 100 63 34, 78 <0.001 a Independent Samples Kruskal–Wallis test. P146 Attitudes and perceptions of adults of 60 years and older towards in-home monitoring of the activities of daily living with contactless sensors: an explorative study V. Claes 1 , E. Devriendt 1 , J. Tournoy 2 , M.D. Deschodt 1 , K. Milisen 1 1 KU Leuven, Leuven, Belgium; 2 University Hospitals Leuven, Leuven, Belgium Introduction: Contactless monitoring is increasingly used to enhance qualitative and cost-effective care for older persons. Succesful implementation of this technology, depends on its acceptance by older people. The purpose was to explore attitudes and perceptions of adults aged ≥60 years towards contactless monitoring. Methods: A questionnaire was developed, validated and used in a cross-sectional survey with a convenience sample (n = 245). Descriptive and bivariate statistics were used for data analysis.

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Page 1: P144: The association of frailty with serum 25-hydroxyvitamin D in older men

S128 Poster presentations, Thursday 18 September 2014 / European Geriatric Medicine 5S1 (2014) S83–S158

Mean gait speed changed from 0.33m/s (baseline) to 0.39m/s

(p = 0.047), from 0.29m/s to 0.42m/s (p = 0.024), and from 0.34m/s

to 0.36m/s (p = 0.450) whereas mean grip strength changed from

4kg (baseline) to 5 kg (p =0.180), from 5.17 kg to 12.17 kg (p =0.027)

and from 2.6 kg to 2.2 kg (p =0.713) in groups A, B and C respectively.

Mean frailty score changed from 5.0 to 3.0 (p = 0.131), from 4.67 to

2.67 (p =0.034), and from 4.4 to 4.0 (p = 0.157) in groups A, B and C

respectively.

Conclusion: Frail elderly must receive both nutritional as well as

exercise intervention for the alleviation of their frail status. Exercise

intervention in the form of nordic walking can be an attractive op-

tion for significant functional improvement in frail older patients.

P144

The association of frailty with serum 25-hydroxyvitamin D

in older men

L. de Buyser, M. Petrovic, Y.E. Taes, K. Toye, J.M. Kaufman,

S. Goemaere

Ghent University, Ghent, Belgium

Introduction: The aim of this study was to determine the

association of frailty with serum 25-hydroxyvitamin D in a

population-based sample of older men.

Methods: Cross-sectional analyses were performed on data from a

longitudinal study in 264 ambulatory men aged 72 to 87 years and

registered in the community of Merelbeke (Ghent, Belgium) in 1997.

Frailty status (robust vs. prefrail or frail) was assessed using the

Study of Osteoporotic Fractures (SOF) index with the components

of weight loss, inability to rise from a chair 5 times without

using arms, and reduced energy level. Serum 25-hydroxyvitamin D

was determined after extraction by radioimmunoassay. Low 25-

hydroxyvitamin D level was defined as <30 ng/ml. Logistic

regression models adjusted for age and body mass index examined

the relationship between (low) 25-hydroxyvitamin D level and

(pre)frailty.

Results: Mean age was 76.7±3.9 years. According to the SOF

index, 181 men (69%) were robust, 79 men (30%) were prefrail or

frail. Serum 25-hydroxyvitamin D concentration was significantly

associated with (pre)frailty (OR per ng/ml decrease = 1.05, 95%CI =

1.01–1.09, P = 0.009). Older men with low 25-hydroxyvitamin D

levels had 2.7 times more odds of being (pre)frail than older men

with normal 25-hydroxyvitamin D levels (OR=2.71, 95%CI = 1.38–

5.40, P = 0.005).

Key conclusions: Our findings suggest that lower serum 25-

hydroxyvitamin D levels are associated with (pre)frailty in

older men.

P145

Nutrition plays a gender-dependent role in disability in an

elderly Sardinian population

D. Concu, G.M. Pes

University of Sassari, Italy

Introduction: In the elderly population the disability rate is lower

in men than in women, although in the latter life expectancy in

generally higher. In Sardinia island a remarkable gender equality

in mortality has been reported (Poulain et al., 2004), but it is

not known if this also holds true for disability. We evaluated the

disability level in a sample of elderly subjects and correlated it with

lifestyle and socio-demographic variables.

Subjects and Methods: One-hundred subjects (50% men, aged

78–93) recruited in the island’s main cities. A comprehensive

assessment was carried out in each participant: ADL, IADL, Barthel

index, MMSE, Exton-Smith and Tinetti scale, km/wk and MNA. The

association of predictors with disability was performed by multiple

linear regression analysis.

Results: Among women the strongest predictors of disability,

as reflected by IADL, were MNA (p=0.0001), SPMSQ (p =0.004)

and Tinetti score (p = 0.001), whereas in males physical activity

expressed as km/wk (p =0.039), the Exton-Smith score (p = 0.0001)

and MMSE (p =0.001) were the most important predictors.

Conclusion: These results suggest that IADL disability in males

is mostly linked to cognitive and motor impairment, whereas

in women is influenced also by a concomitant malnutrition. We

suggest that physical activity is a protective factor for disability in

men, while women lacking this protective mechanism are more

vulnerable to a nutritional deficiency.

P146-1

Frailty and health-related quality of life in ambulatory older

men

L. de Buyser, M. Petrovic, Y.E. Taes, K. Toye, J.M. Kaufman,

S. Goemaere

Ghent University, Ghent, Belgium

Introduction: The aim of this study was to investigate the

relationship between frailty status and health-related quality of

life in a population-based sample of ambulatory older men.

Methods: Cross-sectional analyses were performed on data from a

longitudinal study in 260 ambulatory men aged 72 to 87 years and

registered in the community of Merelbeke (Ghent, Belgium) in 1997.

Frailty status (robust, prefrail, frail) was assessed using the Study of

Osteoporotic Fractures (SOF) index with the components of weight

loss, inability to rise from a chair 5 times without using arms, and

reduced energy level. Health-related quality of life was assessed

using the eight domains of the Short Form-36 questionnaire.

Subjects in the lowest quartile of the distribution were classified

as having ‘poor’ status for each domain. Logistic regression models

adjusted for age examined the relationship between frailty status

and poor status on the Short Form-36 domains.

Results: Mean age was 76.7±3.9 years. According to the SOF index,

181 men (69%) were robust, 69 men (26%) were prefrail, and 10 men

(4%) were frail. The distribution of the Short Form-36 domain scores

differed significantly across frailty statuses (Table 1). Prefrailty and

frailty were significantly associated with increased prevalence of

poor status for all 8 Short-Form 36 domains.

Key conclusions: Our findings suggest that both prefrailty and

frailty are associated with poorer health-related quality of life in

older men, independent of age.

Table 1. Scores on the Short Form-36 domains according to frailty

statusAll (N = 260) Robust (N = 181) Prefrail (N = 69) Frail (N = 10) P a

Median IQR Median IQR Median IQR Median IQR

General Health Perception 65 55, 75 70 60, 80 60 46, 70 48 44, 60 <0.001Physical Function 80 65, 75 90 75, 95 70 51, 80 38 19, 81 <0.001Role Physical 100 50, 100 100 75, 100 75 0, 100 75 19, 100 <0.001Bodily Pain 90 67, 100 90 69, 100 79 56, 100 55 44, 92 0.003General Mental Health 82 72, 92 84 72, 96 76 60, 87 60 52, 70 <0.001Role Emotional 100 67, 100 100 100, 100 100 33, 100 0 0, 100 <0.001Vitality 75 65, 85 80 70, 90 65 51, 80 40 34, 58 <0.001Social Function 100 88, 100 100 88, 100 88 63, 100 63 34, 78 <0.001

a Independent Samples Kruskal–Wallis test.

P146

Attitudes and perceptions of adults of 60 years and older

towards in-home monitoring of the activities of daily living

with contactless sensors: an explorative study

V. Claes1, E. Devriendt1, J. Tournoy2, M.D. Deschodt1, K. Milisen1

1KU Leuven, Leuven, Belgium; 2University Hospitals Leuven, Leuven,

Belgium

Introduction: Contactless monitoring is increasingly used to

enhance qualitative and cost-effective care for older persons.

Succesful implementation of this technology, depends on its

acceptance by older people. The purpose was to explore attitudes

and perceptions of adults aged ≥60 years towards contactless

monitoring.

Methods: A questionnaire was developed, validated and used

in a cross-sectional survey with a convenience sample (n =245).

Descriptive and bivariate statistics were used for data analysis.