Pengetahuan Struktur, Bentuk Dan Sintesa Protein _siti Julaiha

7/23/2019 Pengetahuan Struktur, Bentuk Dan Sintesa Protein _siti Julaiha

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Xol daeh xojx oamhrjkiea jbihr xaglxolt ir

bjmmlh j ~l~xihl daeh%Wole xwa katl jkiea

jbihr jtl ~|x xaglxoltxoly dlbakl j

~amy~l~xihl%

Xol athlt ie woibo jkiea jbihr jtl ~mjblh ie xol bojiehlxltkielr xol rxt|bx|tl ac xol ~taxlie%

Xol rxt|bx|tl ac xol ~taxlie hlxltkielr

xol c|ebxiae ac xol ~taxlie%


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^l~xihl daeh

Jkiea jbih

B+xltkie|rxltkiejxlr dy jbjtdaym gta|~

E+xltkie|rxltkiejxlr

dy je jkiea gta|~

J ~l~xihl0 ^ol+Rlt+Gm|+Myr /C+R+L+F)

Ctak jkiea jbihr xa ~taxlie0
http://c/Users/iyul/Protein%20Engineering/Protein%20(Structur)/peptide_bonding%20[SearchToll].swf


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Xol Roj~l ac ~taxlier0

Abb|trR~aexjela|rmy

Ejxisl baecatkjxiae

hlxltkielh dy hiccltlexMlslmr ac rxt|bx|tl


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Eae basjmlexiexltjbxiaer iesamslh

ie xol roj~l ac~taxlier


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^taxlie baecatkjxiae0 karx ac xol ~taxlier camhiexa aemy ael rxjdml baecatkjxiae at ejxisl

baecatkjxiae

Katl xoje jkiea jbihr dlbaklr j ~taxlie


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^taxlie baecatkjxiae0 karx ac xol ~taxlier camhiexa aemy ael rxjdml baecatkjxiae at ejxisl

baecatkjxiae

Katl xoje jkiea jbihr dlbaklr j ~taxlie


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RLBAEHJTY RXT\BX\TL

Rxjdimiplh dy oyhtagle daehr

O+ daehr jtl dlxwlleBA jehEO gta|~r ac~l~xihl djbfdael

O+daehr jtl lixolt iextj+ at iexlt+ kamlb|mjt 2 xy~lr 0 j+olmi- d+rollx jeh xti~ml+olmi

j Olmi0j olmi baecatkjxiae wjr hirbasltlh yljtr jga ie j fltjxieljd|ehjex ie ojit ejimr- jeh oater

Rollx0hirbasltlh wixoie j yljt ac xol hirbaslty ac j olmi% Ca|eh ie~taxlie cidtaie xol kj`at baerxix|jex ac rimf


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Xol j olmi0tlr|mx ctak oyhtagle daehieg- halr eax iesamsl xol rihl bojie ac xol jkieajbih


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drollx0tlr|mx ctak oyhtagle daehieg- halr eax iesamsl xol rihl bojie ac xol jkiea jbih


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Xti~ml olmi ac Bammjgle

Mikixlh xa xta~abammjgle kamlb|ml

Rlz|lebl kaxic ac/Gmy+_+^ta!Oy~ta)e+

2 mlcx+ojehlh olmiblr wa|eh xaglxolt xa gisl jtigox+ojehlh r|~ltolmi

Rxjdml r|~ltolmi 0 gmybielr mabjxlh ae xolblextjm jir /rkjmm T gta|~) ac xti~ml olmi

Ael iexltbojie O+daeh cat ljbo xti~mlx ac jjr dlxwlle EO ac Gmy jeh BA ac _ /at ^tamiel)ie xol jh`jblex bojie

XTI^ML OLMI_


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Oyhta~oimi

b

Xol taml ac rihl bojie ie xol roj~l ac ~taxlier

Oyhta~oadib


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J baimlh+baim0Rxt|bx|tl abb|tr wole xol 4 jolmi ojsl karx ac xolit eae~amjt/oyhta~oadib) rihl bojier ae aelrihl- ra xojx xoly bje xwirx jta|eh

ljbo axolt wixo xolrl rihl bojiecjbieg iewjthr


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Z|jxlteltyrxt|bx|tl0

Ic ~taxlie ir catklh jr jbak~ml ac katl xoje ael

~taxlie bojie- xol bak~mlxlrxt|bx|tl ir hlrigelh jrz|jxltelty rxt|bx|tl0

Gleltjmmy catklh dy eae+basjmlex iexltjbxiaerdlxwlle r|d|eixr

Lixolt jr oaka+ at

olxlta+k|mxikltr


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^tikjty rxt|bx|tl

Rlbaehjty rxt|bx|tl

Xltxijty rxt|bx|tl

Z|jxltejty rxt|bx|tl


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^taxlie hakjier

Byxabotakl d


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^taxlie Camhiegir xol ~oyribjm ~tablrr dy woibo j ~amy~l~xihl camhr iexa ixr bojtjbxltirxib jeh

c|ebxiaejm xotll+hikleriaejm rxt|bx|tl ctak tjehak baim%V:[ Ljbo ~taxlie lirxr jr

je |ecamhlh ~amy~l~xihl at tjehak baim wole xtjermjxlh ctak j rlz|leblackTEJ xa j mieljt bojie ac jkiea jbihr%Xoir ~amy~l~xihl mjbfr jey hlslma~lh xotll+hikleriaejm rxt|bx|tl%Jkiea jbihr iexltjbx wixo ljbo axolt xa ~tah|bl j wlmm+hlcielh xotll hikleriaejmrxt|bx|tl- xol camhlh ~taxlie- feawe jr xol ejxisl rxjxl% Xol tlr|mxieg xotll+hikleriaejm rxt|bx|tl ir hlxltkielh dy xol jkiea jbih rlz|lebl%

Cat kjey ~taxlier xol battlbx xotll hikleriaejm rxt|bx|tl ir lrrlexijm xac|ebxiae% Cjim|tl xa camh iexa xol iexlehlh roj~l |r|jmmy ~tah|blr iejbxisl~taxlier wixo hiccltlex ~ta~ltxilr iebm|hieg xaib ~tiaer%Rlsltjm el|tahlgleltjxisl jeh axolt hirljrlr jtl dlmilslh xa tlr|mx ctak xol

jbb|k|mjxiae ac kircamhlh/iebattlbxmy camhlh) ~taxlier%

Kjey jmmltgilr jtl bj|rlh dy xol camhieg ac xol ~taxlier- cat xol ikk|el ryrxlkhalr eax ~tah|bl jexidahilr cat bltxjie ~taxlie rxt|bx|tlr%

C xi c x i
http://en.wikipedia.org/wiki/Polypeptidehttp://en.wikipedia.org/wiki/Protein_structurehttp://en.wikipedia.org/wiki/Random_coilhttp://en.wikipedia.org/wiki/Proteinhttp://en.wikipedia.org/wiki/Polypeptidehttp://en.wikipedia.org/wiki/Random_coilhttp://en.wikipedia.org/wiki/MRNAhttp://en.wikipedia.org/wiki/Amino_acidhttp://en.wikipedia.org/wiki/Native_statehttp://en.wikipedia.org/wiki/Prionhttp://en.wikipedia.org/wiki/Neurodegenerativehttp://en.wikipedia.org/wiki/Diseasehttp://en.wikipedia.org/wiki/Protein_allergyhttp://en.wikipedia.org/wiki/Protein_allergyhttp://en.wikipedia.org/wiki/Diseasehttp://en.wikipedia.org/wiki/Neurodegenerativehttp://en.wikipedia.org/wiki/Prionhttp://en.wikipedia.org/wiki/Native_statehttp://en.wikipedia.org/wiki/Amino_acidhttp://en.wikipedia.org/wiki/MRNAhttp://en.wikipedia.org/wiki/Random_coilhttp://en.wikipedia.org/wiki/Polypeptidehttp://en.wikipedia.org/wiki/Proteinhttp://en.wikipedia.org/wiki/Random_coilhttp://en.wikipedia.org/wiki/Protein_structurehttp://en.wikipedia.org/wiki/Protein_structurehttp://en.wikipedia.org/wiki/Protein_structurehttp://en.wikipedia.org/wiki/Polypeptidehttp://c/Users/iyul/Protein%20Engineering/Protein%20Folding/protein_folding.swf


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C|ebxiae ac ~taxlier

Lepykjxib bjxjmyrir

Xtjer~atx jeh rxatjgl /xol ~taxlie olkagmadie- jmd|kier)

Baathiejxlh kaxiae /jbxie jeh kyarie)%

Klbojeibjm r|~~atx/bammjgle)%

Ikk|el ~taxlbxiae/jexidahilr)

Gleltjxiae jeh xtjerkirriae ac eltsl ik~|mrlr+ rakl

jkiea jbihr jbx jr el|taxtjerkixxltr- tlbl~xatr catel|taxtjerkixxltr- ht|gr- lxb% jtl ~taxlie ie ejx|tl% /xol

jblxymboamiel tlbl~xat)-

Baextam ac gtawxo jeh hiccltlexijxiae+ xtjerbti~xiae cjbxatr

Oatkaelr gtawxo cjbxatr / ier|mie at xoytaih rxik|mjxiegoatkael)


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Lepyklr

Lepyklr jtl ~taxlier xojx bjxjmypl /i%l% r~llh |~)bolkibjm tljbxiaer% Lepyklr jtl bjxjmyrxr%

Lepyklr watf ae xoiegr bjmmlh R|drxtjxlr

Ljbo lepykl ir r~lbicib cat ixr r|drxtjxlJmkarx jmm ~tablrrlr ie j blmm ellh lepyklr ie athlt xa

abb|t jx rigeicibjex tjxlr%

Lepyklr jtl eax |rlh |~ dy xol tljbxiae%Jcxlt xoly ojsl hael xolit watf xoly tlmljrl xol ~tah|bxr

jeh jtl eax bojeglh Ljbo lepykl bje watf ae kjey kamlb|mlr ac xol r|drxtjxl


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Mabf jeh Fly Kahlm Xol klxoah ie woibo lepyklr watf ir bjmmlh xol mabf

jeh fly kahlm


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Xtjer~atx jeh rxatjgl+rkjmm kamlb|mlr jtl acxle bjttilh dy ~taxlierie xol ~oyriamagibjm rlxxieg /cat ljk~ml- xol ~taxlie olkagmadie ir tlr~aeridmlcat xol xtjer~atx ac aygle xa xirr|lr)% Kjey ht|g kamlb|mlr jtl ~jtxijmmy da|ehxa rlt|k jmd|kier ie xol ~mjrkj%

2+hikleriaejm rxt|bx|tl ac olkagmadie%Xol ca|t r|d|eixr jtl roawe ie tlh jehylmmaw- jeh xol olkl gta|~r ie gtlle%

Xol diehieg ac aygle ir jcclbxlh dy kamlb|mlr r|bo jrbjtdae kaeaihl /BA) /cat ljk~ml ctak xadjbbarkafieg- bjtr jeh c|tejblr)%

BA bak~lxlr wixo aygle jx xol olkl diehieg rixl%Olkagmadie diehieg jccieixy cat BA ir 4>> xiklr gtljxltxoje ixr jccieixy cat aygle- kljeieg xojx rkjmm jka|exrac BA htjkjxibjmmy tlh|blr olkagmadie'r jdimixy xaxtjer~atx aygle% Wole olkagmadie bakdielr wixoBA- ix catkr j slty dtigox tlh bak~a|eh bjmmlhbjtdayolkagmadie%

Wole ier~itlh jit baexjier BA mlslmr jr maw jr >%>4,-oljhjbol jeh ej|rlj abb|t6 ic xol BA baeblextjxiae iriebtljrlh xa >%:,- |ebaerbia|relrr wimm cammaw% Ieoljsy rkafltr- |~ xa 4>, ac xol aygle+jbxisl rixlrbje dl dmabflh dy BA%

B


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Baathiejxlh kaxiae+ k|rbml ir karxmy ~taxlie- jeh k|rbml baextjbxiae irklhijxlh dy xol rmihieg kaxiae ac xwa ~taxlie cimjklexr- jbxie jeh kyarie%

^mjxlmlx dlcatl jbxisjxiae Jbxisjxlh ~mjxlmlxJbxisjxlh ~mjxlmlxjx j mjxlt rxjgl xoje B)

^mjxlmlx jbxisjxiae ir j baextammlhrlz|lebl ac jbxie cimjklex0

Rlsltieg\ebj~~iegLmaegjxiegBtarr miefieg

Xojx btljxlr j htjkjxib roj~lbojegl ie xol ~mjxlmlx


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Ikk|el ~taxlbxiae+ jexidahilr jtl ~taxlie rxt|bx|tlr xojx jtl

tlr~aeridml cat tljbxieg wixo r~lbicib catlige r|drxjeblr ie xol dahy%


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Gleltjxiae jeh xtjerkirriae ac eltsl ik~|mrlr

GJDJ0gjkkj Jkiea d|xytib jbihRyexolrirlh ctak gm|xjkjxl

GJDJ jbxr jx ieoidixaty ryej~rlr ie xoldtjie% GJDJ jbxr dy diehieg xa r~lbicibtlbl~xatr ie xol ~mjrkj klkdtjel ac daxo~tl+ jeh ~arxryej~xib el|taer%

El|taxtjerklxxlt

Rakl jkiea jbihr jbx jr el|taxtjerkixxltr- woibo xtjerkix lmlbxtibjm

rigejmr ctak ael eltsl blmm xa jeaxolt% Ie jhhixiae- tlbl~xatr catel|taxtjerkixxltr- ht|gr- lxb% jtl ~taxlie ie ejx|tl%

Je ljk~ml ac xoir ir xol jblxymboamiel tlbl~xat- woibo ir j ~taxlierxt|bx|tl xojx ir lkdlhhlh ie ~arxryej~xib el|taer%

Baextam ac gtawxo jeh hiccltlexijxiae +


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~taxlier bje dl btixibjm xa xol baextam ac gtawxo- blmm hiccltlexijxiae jeh l~tlrriae acHEJ%

Cat ljk~ml- tl~tlrrat ~taxlier kjy dieh xa r~lbicib rlgklexr ac HEJ-~tlslexieg l~tlrriae jeh xo|r xol catkjxiae ac xol ~tah|bx ac xojx HEJrlgklex%

Jmra- kjey oatkaelr jeh gtawxo cjbxatr xojx tlg|mjxl blmm c|ebxiae- r|bo jr

ier|mie at xoytaih rxik|mjxieg oatkael jtl ~taxlier%

Baextam ac gtawxo jeh hiccltlexijxiae


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Botakarakl

R|~ltbaimr

Baimr

E|bmlarakl

Oirxaelr

HEJ

ha|dml

olmi


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Eixtaglea|r Djrlr Xwa xy~lr0

^|tielr /xwa tiegr)

^ytikihielr /ael tieg)

^|tielr Jhleiel jeh G|jeiel

^ytikihielr

Xoykiel jeh Byxariel


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^|tielr ^ytikihielr

Jhleiel G|jeiel Byxariel Xoykiel

^oar~ojxlgta|~

Hlaytidarl


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Daehieg

J B G G X J

XLK^MJXL RXTJEH

X XG B B J

Wljf OYHTAGLE daehr catk

dlxwlle xol Eixtagle Djrl ^jitr%


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Bojtgjccr t|mlr0 Djrl ~jitieg t|ml ir J+X jeh G+B

Xoykiel ir tl~mjblh dy \tjbim ie TEJ

Djrlr jtl daehlh xa ljbo axolt dy Oyhtagle daehr Hirbasltlh dlbj|rl ac xol tlmjxisl ~ltblex ac ljbo

djrl6 /eaxibl xojx J+X ir rikimjt jeh B+G jtl rikimjt)

HEJ Rxt|bx|tl


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Xol djbfdael ac ix jmm

J B G G X J

XLK^MJXL RXTJEH

X XG B B J

Xol djbfdael ir kjhl ac jmxltejxieg

r|gjtr jeh ~oar~ojxlr%+ Tlklkdlt0 R|gjtJMWJYRjxxjbolr xa xol Eixtagle djrl


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Glelxib Bahl

Glelxib bahl xol mjeg|jgl ac kTEJierxt|bxiaer /dm|l~tiexr)

Tljh ie xotll mlxxltr jx j xikl

Ljbo mlxxlt tl~tlrlexr ael ac xol eixtaglea|rdjrlr0 J- \- B- G

Bahaeca|eh ae kTEJ6 baerirxr ac xotll djrlr/ael tigox jcxlt xol axolt)

38 bahaer cat 4> jkiea jbihr

Bahae /baexh)


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Bahae /baex h)

Cat ljk~ml- baerihlt xol cammawieg TEJ

rlz|lebl0\BGBJBGG\

Xol rlz|lebl wa|mh dl tljh xotll djrl ~jitr jx j

xikl0\BG BJB GG\

Xol bahaer tl~tlrlex xol jkiea jbihr0

Rltiel Oirxihiel GmybielJ\G rxjtx bahae at Klxoiaeiel

\JJ- \JG- \GJ rxa~ bahaer6 bahl cat eaxoieg6

mifl xol ~ltiah jx xol leh ac j rlexlebl


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Xol glel+lepykl tlmjxiaeroi~ ojr dlle

tlsirlh xa xol ael+glel- ael+~amy~l~xihltlmjxiaeroi~%

Ljk~ml0 Ie olkagmadie- ljbo ~amy~l~xihlbojie ir r~lbicilh dy j rl~jtjxl glel%

Axolt glelr bahl cat TEJ xojx ir eax

xtjermjxlh xa ~amy~l~xihlr6 rakl glelr jtliesamslh ie baextammieg axolt glelr%


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HEJ # TEJ


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Rxl~r ac HEJ Tl~mibjxiae

:) HEJ k|rx |ewieh jeh dtljf xol oyhtagle daehr

4) Ljbo rxtjeh ir |rlh jr j xlk~mjxl /dm|l~tiex)

2) Xwa elw rxtjehr ac HEJ jtl catklh ctak xolatigiejm rxtjeh dy xol lepykl HEJ ^amykltjrl


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HEJ

Xtjerbti~xiae

H|tieg tl~mibjxiae- je lepykl bjmmlh olmibjrl |epi~r xol


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HEJ kamlb|ml jmaeg xol djrl ~jitieg- rxtjigox hawe xolkihhml%Jeaxolt lepykl- bjmmlh HEJ ~amykltjrl- kaslr jmaeg xoldjrlr ae ljbo ac xol |epi~~lh ojmslr jeh baeelbxrbak~mlklexjty e|bmlaxihlr%

Ctak Glel xa ^taxlie
http://c/Users/iyul/Transcription%20[www.keepvid.com].mp4


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Ryexolrir ac HEJctak TEJ irtlsltrlxtjerbti~xiae%

Sit|rlr xojx haxoir jtl

Tlxtasit|rlr%
http://c/Users/iyul/Protein%20Engineering/Reverse%20Transcription%20FORM%20CDNA/cDNA%20Complementary%20DNA%20[SearchToll].swf


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Ljbo glel ojr ix awe ~takaxatLjbo glel ir wihlmy r~jbilhXol iecatkjxiae ir ctjgklexlhLae ; l~tlrrlh gleIextae ; iexltsleieg ~jtx

R~mibieg

Jmxltejxisl r~mibieg0 J tlg|mjxaty klbojeirk dy woibosjtijxiaer ie xol iebat~atjxiae ac j glelr laer- at bahiegtlgiaer- iexa klrrleglt TEJ mljh xa xol ~tah|bxiae ac katl

xoje ael tlmjxlh ~taxlie- at iracatk%Jmxltejxisl r~mibieg ir j ra|tbl ac glelxib hisltrixy iel|fjtyaxlr%R~mibieg ojr dlle |rlh xa jbba|ex cat xol tlmjxislmy rkjmme|kdlt ac glelr ie xol o|kje gleakl%

kTEJ R~mibieg


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~ g

Xol lexitl glel ir xtjerbti~xlh iexa j klrrjgl% Rakl ac

xol klrrjgl ir@|ef /iextaer) jeh ir tlkaslh dlcatl lixieg xol e|bml|r%

J r~miblarakl ir j bak~ml ac r~lbijmiplh TEJ jeh ~taxlie

xojx tlkaslr iextaer ctak j ~tl+kTEJ Xoir ~tablrr irgleltjmmy tlclttlh xa jr r~mibieg%

Iextaerxy~ibjmmy ojsl j G\ e|bmlaxihl rlz|lebl jx xol


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G|xxkjbolt jeh Bammier - EL@K- 287 /:9)0 :>4


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Xtjermjxiae+ xol \mxikjxl Gajm*


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Xtjermjxiae xol \mxikjxl Gajm*Gaieg ctak kTEJ xa xol ciejm ~tah|bx

Xtjerbti~xiae+ oaw TEJ ir kjhl


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Xtjerbti~xiae oaw TEJ ir kjhl@|rx jr HEJ ~amykltjrl kjflr elw HEJ- j rikimjtlepykl bjmmlh TEJ ~amykltjrl kjflr elw TEJ%

TEJ ~amykltjrl xlk~atjtimy rl~jtjxlr xol rxtjehr ac jrkjmm rlbxiae ac xol HEJ kamlb|ml% Xoir l~arlr rakl acxol djrlr ac xol HEJ kamlb|ml%

Jmaeg ael rxtjeh- xol TEJ ~amykltjrl diehrbak~mlklexjty TEJ e|bmlaxihlr xa xol l~arlh HEJdjrlr%

Je l~arlh xoykiel ae xol HEJ rxtjeh oaafr |~ wixo

je TEJ e|bmlaxihl wixo je jhleiel6 je l~arlh byxarielae xol HEJ oaafr |~ wixo je TEJ e|bmlaxihl wixo jg|jeiel djrl6 je l~arlh jhleiel HEJ djrl wimm oaaf |~

wixo \TJBIM*

Jr xol TEJ ~amykltjrl kaslr jmaeg ix kjflr j


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Jr xol TEJ ~amykltjrl kaslr jmaeg- ix kjflr jrxtjeh acklrrleglt TEJ /kTEJ)%

Ix ir bjmmlh klrrleglt TEJ dlbj|rl ix bjttilr HEJrklrrjgl a|x ac xol e|bml|r jeh iexa xol byxa~mjrk%

kTEJ ir RIEGML RXTJEHLH*

Wole xol TEJ ~amykltjrl ir hael tljhieg xol glel

ie xol HEJ- ix mljslr% Xol rl~jtjxlh HEJ rxtjehr tlbaeelbx- tljhy xa dltljh jgjie wole elblrrjty%

kTEJ kaslr a|x ac xol e|bml|r jeh ciehr j tidarakl Ae xol tidarakl- jkiea jbihr jtl jrrlkdmlh xa catk~taxlier ie xol ~tablrr bjmmlh xtjermjxiae%

Xtjermjxiae0 ^taxlie Ryexolrir


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Xtjermjxiae0 ^taxlie Ryexolrir:)kTEJ ir xtjerbtidlh ie xol e|bml|r jeh mljslr

xol e|bml|r xa xol byxa~mjrk4) kTEJ jxxjbolr xa xol tidarakl

2)xTEJ bjttilr xol jexibahae woibo ~jitr |~

wixo xol bahae ae xol kTEJ8) xTEJ dtiegr xol battlbx jkiea jbih dy tljhiegxol glelxib bahl


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Xtjermjxiae

G\J \B\ G\\ JBB G\JkTEJ

kTEJ bjttilr xol rjkl klrrjgl jr HEJ d|xtlwtixxle wixo hiccltlex eixtagle djrlr%

Xoir klrrjgl bahlr cat j r~lbicib rlz|lebl acjkiea jbihr

Tlsilw%%Jkiea jbihr jtl xol d|imhieg dmabfrac

^TAXLIER


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RA0Rjy xol kTEJ rxtjeh tljhr0

kTEJ /bahae) J\GGJBBJG+\GJ xTEJ /jexibahae) \JB+B\G+G\B+JB\

xTEJ wa|mh dtieg xol jkiea jbihr0Klxoiaeiel+Jr~jtxib jbih+Gm|xjkiel+rxa~

Xtjermjxiae


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G\J \B\ G\\ JBB G\J

Xtjermjxiae

Bahae0 j rlz|lebl ac 2 eixtagle djrlr aekTEJ xojx bahl cat : jkiea jbih

Ixr j XTI^MLX bahl

Ljk~ml0 Xoir rxtjeh ac kTEJ ojr jkiea jbihr ae ljtxo%


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Xol glelxib bahl0 r~lbicilr woibo jkieajbihr wimm dl |rlh xa d|imh j ~taxlie

Bahae0 j rlz|lebl ac xotll djrlr% Ljbo

bahae r~lbicilr j ~jtxib|mjt jkiea jbih%Rxjtx bahae0 J\Gieixijxiae rigejm catxtjermjxiae

Rxa~ bahaer0 rxa~r xtjermjxiae jeh~amy~l~xihl ir tlmljrlh


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Bahaer kjxbo|~ wixo

jexibahaer xabtljxl j

~taxlie

Cig|tl :4%3 Xol Glelxib Bahl


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Xtjermjxiae


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kTEJ

G\J \B\ G\\ JBB G\J

Xol kTEJ kamlb|ml xtjslmr xa xol tidaraklrwoltl xol kTEJ bahlr jtl tljh dy xol

tidaraklrTidaraklr oamh xol kTEJ ra jeaxolt xy~lac TEJ- xtjerclt TEJ /xTEJ) bje jxxjbo xa xolkTEJ

Xtjermjxiae

Tidarakl

Xtjermjxiae


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kTEJ

Xtjermjxiae

G\J \B\ G\\ JBB G\J

B \JJG J

Tidarakl

Xtjermjxiae


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G\J \B\ G\\ JBB G\JkTEJ

B \J JG J BJ J

Xtjermjxiae

Lmlklexr ac xtjermjxiae


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Tidaraklr

tTEJ

Mjtgl jeh rkjmm r|d|eixr

Bahaer

Ieixijxat at rxjtx bahae

Klxoiaeiel /J\G)

Rxa~ bahaer

xTEJ

Ieixijxiae

Bojie Lmaegjxiae^l~xihl daehr

Bojie xltkiejxiae

^amyrakl

Lmlklexr ac xtjermjxiae


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TEJ

Tidae|bmlib jbih

Riegml+rxtjehlh olmiR|gjt ir tidarl

Xoykiel ir tl~mjblh dy \TJBIM

Kj`at TEJr


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kTEJklrrleglt TEJ bjttilr xol glelxib iecatkjxiae xojx wimm dl

l~tlrrlh |mxikjxlmy jr ~taxlier% /bjttilr iecatkjxiae ctakHEJ xa tidarakl)

xTEJxtjerclt TEJ ir xol jhj~xlt kamlb|ml% Ix tlbageiplr xol bahaerac xol kTEJ ae xol ael ojeh- jeh ix bje dl basjmlexmy daehlhxa xol j~~ta~tijxl jkiea jbih- ae xol axolt% /Bjttilr jkieajbihr)

tTEJtidarakjm TEJ ir ca|eh ie xol tidaraklr /Kjflr |~

tidaraklr)

TEJ+Bahieg Glelr


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J% Tidarakjm TEJ /tTEJ) glelr

D% Xtjerclt TEJ /xTEJ) glelr

B% Rkjmm E|bmljt TEJ /reTEJ) glelr

H% Rkjmm E|bmlamjt TEJ /reaTEJ) glelr

L% Tlg|mjxaty TEJ glelr

C% _IRX TEJ+Bahieg Glelr

G% KibtaTEJ /kiTEJ) glelr

O% Jexirlerl TEJ glelr

I% Tidarwixbo glelr

TEJ


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ctak xa xa kjfl |~

jmra bjmmlh woibo c|ebxiaer xa jmra bjmmlh jmra bjmmlhwoibo c|ebxiaer xa

bje dl

KlrrlegltTEJ

TidarakjmTEJ

XtjercltTEJ

kTEJ Bjttyierxt|bxiaer

tTEJBakdiel

wixo ~taxlier xTEJ

Dtiegjkiea

jbihr xatidarakl

HEJ Tidarakl Tidaraklr


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^tablrrieg xol TEJ xtjerbti~x iexa kTEJ


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:% Kaea+birxtaeib4% Kjx|tjxiae

j) TEJ bj~~ieg

d) TEJ ~amyjhleymjxiae

b) TEJ r~mibieg

^tablrrieg xol TEJ xtjerbti~x iexa kTEJ

Birxtae ; Glel

Kjx|tjxiae ac L|fjxtiaxib kTEJ


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Iextae0 eax ca|ehlh ie byxa~mjrkBj~0 7+Klxoym+G|jeariel bj~- ~taxlbx kTEJctak hlgtjhjxiae jeh rltsl jr j tidarakldiehieg rixl^amy+J xjim0 JJ\JJJ /4>> Jr) xa ~taxlbx xolklrrjgl ctak hlgtjhjxiaeR~mibieg0 tlkasl ac iextaerMjtijx rxt|bx|tlr0 iextaer tlkaslh ctak oeTEJ/olxltaglel|r e|bmljt TEJ) jtl hlgtjhlh iee|bml|r


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Xtjerclt TEJ


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Xol baecatkjxiae/xotll+hikleriaejm

roj~l) ac xTEJ tlr|mxr ctak djrl~jitieg /O daehr) wixoie xol kamlb|ml%

2' leh ir xol jkiea jbih jxxjboklexrixldiehr basjmlexmy% Jmwjyr BBJ%

Jexibahae0 rixl ac djrl ~jitieg wixokTEJ% \eiz|l cat ljbo r~lbilr acxTEJ%


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Oyhtagle daehr catk dlxwlle xol

jexibahae ac xTEJ jeh xol bahae ackTEJ%

Rkjmm r|d|eix tTEJ sjmihjxlr xolkjxboic oyhtagle daehr ojsl eaxcatklh dlxwlle jmm xotll djrl ~jitr-ix k|rx dl je iebattlbx kjxbo- jehxol xTEJ ir tl`lbxlh%


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Ljk~ml0

HEJ bahae cat jtgieiel0 2'+GBB+


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Waddml0 r~lbicibixy cat xol djrl jx xol 2'

leh ac xol bahae ir eax jmwjyradrltslh%

Ljk~ml0 bahaer cat jmjeielGBJ-

GBB- jeh GB\jtl tlbageiplh dy xolrjkl xTEJ%


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^taxlie catkjxiae


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Jkiea jbihr miefxaglxolt xa catk j~taxlie

Xol elw ~taxlie

ba|mh dlbakl blmm~jtx- je lepykl- joatkael lxb%


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Tidarakib TEJ


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^tafjtyaxib tidaraklr

ojsl 2 tTEJkamlb|mlr042R- :3R jeh R

L|fjtyaxib tidaraklrojsl 8 tTEJ

kamlb|mlr04?R- :?R- R

8>R

3>R

2>R

R


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Tidarakl0 xol watfdlebooamhr kTEJ jeh

xTEJ ie xol battlbx ~arixiaer xa jmmawjrrlkdmy ac ~amy~l~xihl bojie%

Tidaraklr jtl eax r~lbicib- xoly bje kjfl jey

xy~l ac ~taxlie%


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^tafjtyaxlrRkjmm R|d|eix 2>r Mjtgl r|d|eix r

:3r R Mjtgl 3>R


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R|d|eixr jtl olmh xaglxolt dy iaeib jeh

oyhta~oadib catblr /eax basjmlexdaehr)%

Wole eax jbxisl ie xtjermjxiae- xolr|d|eixr lirx rl~jtjxlmy%

Cig|tl :4%:> Tidarakl Rxt|bx|tl


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Mjtgl r|d|eix ojr xotll xTEJ diehieg

rixlr0

J rixl diehr wixo jexibahae acbojtglh xTEJ%

^ rixl ir woltl xTEJ jhhr ixr jkieajbih xa xol gtawieg bojie%

L rixl ir woltl xTEJ rixr dlcatldlieg tlmljrlh%


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TEJ ~amykltjrlr

bjxjmypl ryexolrir acTEJ%

TEJ ~amykltjrlr jtl~tablrrislj riegmllepykl+xlk~mjxldiehieg tlr|mxr ie

~amykltipjxiae aco|ehtlhr ac TEJdjrlr%

Cig|tl :4%8 TEJ ^amykltjrl


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Wojx jtl xol daehr bjmmlh xojxcatk dlxwlle tidarl djrlr1


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Xtjerbti~xiae abb|tr ie xotll ~ojrlr0

Ieixijxiae

Lmaegjxiae

Xltkiejxiae

oxx~0!!sblmm%ehr|%lh|!jeikjxiaer!xtjerbti~xiae!kasil%oxk
http://vcell.ndsu.edu/animations/transcription/movie.htmhttp://vcell.ndsu.edu/animations/transcription/movie.htm


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Ieixijxiae tlz|itlr j ~takaxltj r~lbijm

rlz|lebl ac HEJ%

TEJ ~amykltjrl diehr xa xol ~takaxlt%

^takaxlt xlmmr TEJ ~amykltjrl woltl xa rxjtx-woibo hitlbxiae xa ga ie- jeh woibo rxtjeh acHEJ xa xtjerbtidl%

^jtx ac ljbo ~takaxlt ir xol ieixijxiae rixl%


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HEJ Ir Xtjerbtidlh xa Catk TEJ /J)


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oxx~0!!www%diarx|hia%bak!hlkaQctllkjeQ~taxlieQryexolrir%oxk
http://www.biostudio.com/demo_freeman_protein_synthesis.htmhttp://www.biostudio.com/demo_freeman_protein_synthesis.htmhttp://www.biostudio.com/demo_freeman_protein_synthesis.htmhttp://www.biostudio.com/demo_freeman_protein_synthesis.htm


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RXL^ :

Rxl~ 4


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Rxjtx bahae ir J\G6 citrx jkiea jbih ir

jmwjyr klxoiaeiel- woibo kjy dltlkaslh jcxlt xtjermjxiae%

Xol mjtgl r|d|eix `aier xol bak~ml- xolbojtglh xTEJ ir eaw ie xol ^ rixl ac xolmjtgl r|d|eix%


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Lmaegjxiae0 TEJ ~amykltjrl |ewiehr

HEJ jda|x :> djrl ~jitr jx j xikl6tljhr xlk~mjxl ie 2' xa


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Lmaegjxiae0 xol rlbaeh bojtglh xTEJ

lexltr xol J rixl%

Mjtgl r|d|eix bjxjmyplr xwa tljbxiaer0

:% Dtljfr daeh dlxwlle xTEJ ie ^ rixljeh ixr jkiea jbih%

4% ^l~xihl daeh catkr dlxwlle xojxjkiea jbih jeh xol jkiea jbih ae xTEJie xol J rixl%


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Xltkiejxiae0 xtjermjxiae lehr wole j

rxa~ bahae lexltr xol J rixl%

Rxa~ bahae diehr j ~taxlie tlmljrlcjbxatjmmawr oyhtamyrir ac daehdlxwlle ~amy~l~xihl bojie jeh xTEJ aexol ^ rixl%

^amy~l~xihl bojieB xltkie|r ir xol mjrxjkiea jbih jhhlh%


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Xjdml :4%:


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Rlsltjm tidaraklr bje watf xaglxolt xa

xtjermjxl xol rjkl kTEJ- ~tah|biegk|mxi~ml ba~ilr ac xol ~amy~l~xihl%

J rxtjeh ac kTEJ wixo jrrabijxlhtidaraklr ir bjmmlh j ~amytidarakl at~amyrakl%


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Cig|tl :4%:8 J ^amyrakl /^jtx :)


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Cig|tl :4%:8 J ^amyrakl /^jtx 4)


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http://c/Users/iyul/Translation%20[www.keepvid.com].mp4http://c/Users/iyul/Protein%20Synthesis_%20Translation%20Process%20[www.keepvid.com].mp4http://c/Users/iyul/Transcription%20[www.keepvid.com].mp4


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^ m i m c i o i

Rxjdimipieg xol klrrjgl


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^arxxtjermjxiaejmjr~lbxr ac ~taxlie ryexolrir0

Oaw ir j klrrjgl/kTEJ) rxjdimiplhxa glx lea|go

~taxliejx xoltigox xikl1

:%


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4% ^amyjhleymjxiae ir xol ryexolrir ac j ~amy/J) xjim- j rxtlxbo

ac jhleielr jx xol leh ac xol kTEJ kamlb|ml%

Jx xol leh ac xtjerbti~xiae xol mjrx 2 dix ac xol elwmy kjhl

TEJ ir bmljslh acc dy j rlx jac lepyklr% Xol lepyklr xoleryexolripl xol ~amy/J) xjim jx xol TEJ'r 2' leh%

Xol ~amy/J) xjim ir ik~atxjex cat xol e|bmljt l~atx- xtjermjxiaejeh rxjdimixy ac kTEJ% Xol xjim ir roatxlelh aslt xikl jehwole ix ir roatx lea|go- xol kTEJ ir hlgtjhlh%

Ie j clw blmm xy~lr- kTEJr wixo roatx ~amy/J) xjimr jtl rxatlhcat mjxlt jbxisjxiae


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^tablrrieg xol ~taxlie /~tah|bx)

2% XJTGLXIEG0

^amy~l~xihl kjy dl kaslh ctak ryexolrir rixl xa jeatgjelmml- at a|x ac xol blmm%

Jkiea jbih rlz|lebl jmra baexjier j rigejm rlz|leblje jhhtlrr mjdlm%

i%l% ~taxlier xjtglxlh xa LT oyhta~oadib jkiea jbihrae xol E+xltkie|r%

Hlrxiejxiaer cat Elwmy Xtjermjxlh ^amy~l~xihlr ie j L|fjtyaxib Blmm
http://en.wikipedia.org/wiki/N-terminal_endhttp://en.wikipedia.org/wiki/N-terminal_endhttp://en.wikipedia.org/wiki/N-terminal_endhttp://en.wikipedia.org/wiki/N-terminal_end


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J Rigejm Rlz|lebl Kaslr j ^amy~l~xihl iexa xol LT /^jtx :)


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Cig|tl :4%:3 J Rigejm Rlz|lebl Kaslr j ^amy~l~xihl iexa xol LT /^jtx 4)

Camhieg boj~ltaelr /~taxlier)


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ie TLT camh ~taxlier j~~ta~tijxlmy%

Kir+camhieg hirljrlr0

Jmxpolikltr

Btl|xpclmh@jfad hirljrl /B@H) /~tiae hirljrl)

^


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Jmm ~taxlier ierltxlh iexa at jrrabijxlh wixoxol blmm klkdtjel ojsl r|gjtr jxxjbolh xaxolk% Xoly jih ie tlbageixiae ac axoltkamlb|mlr%

Wojx wa|mh dl rakl baerlz|leblr aciebattlbx gmybarymjxiae jx xol blmm

klkdtjel1

Wojx Oj~~ler xa ^amy~l~xihlr jcxlt Xtjermjxiae1


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^taxlie kahicibjxiaer0


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Documents

Pengetahuan Struktur, Bentuk Dan Sintesa Protein _siti Julaiha