PHOTOACOUSTIC IMAGING AND SPECTROSCOPY

Contents Preface ....... .. ... ·· ········································· ··················· ············ ··· ··· ·· ····· ··· ···· ··············.·.· ········· ···································· ... ...... .. ··. xiii Editor .. ....... ..... ....... .. ..... ............... ...... ... ......................... ... .. ........... ..... .. ............. ...... ........ .... .. ....... .............. ................ .......... .. ... xv Contributors ......... ................. ...... ... ... .. .... ..... .. .... ......... .... .... ... .... .... .... .. ...... .. .................... ...... ........ .... ..... .......... .... ... .... ........... xvii

PART I Fundamentals of Photoacoustics

Chapter 1 Photoacoustic Monopole Radiation: Waves from Objects with Symmetry in One, Two, and Three Dimensions ........... ...... .. .............. ...... ... ........ .... ..... .................... ...................... 3

Gerald. J. Diebold

Chapter 2 Photoacoustic Doppler Effect and Flow Sensing ............... ............ ...... ......... .... ... ....... ........... .... .................. ...... ... 19

Hui Fang and Lihong V. Wang

Chapter 3 Modeling Photoacoustic Propagation in Tissue Using k-Space Techniques ................... ........... ...... ..... ......... ....... 25

Ben Cox and Paul C. Beard

PART II Photoacoustic Image Reconstruction: Algorithm, Resolution, and View

Chapter 4 Universal Back-Projection Algorithm for Photoacoustic Tomography ................................................................. 37

Minghua Xu and Lihong V. Wang

Chapter 5 Analysis of Spatial Resolution in Photoacoustic Tomography ..... ................... ........ ..... .. ................. .. .................... 47

Minghua Xu and Lihong V. Wang

Chapter 6 Limited View Thermoacoustic Tomography .................................... .... ....... ...... ... ............. ........ ................ ........... 61

Yuan Xu, Lihong V. Wang, Gaik Ambartsoumian, and Peter Kuchment

PART Ill Photoacoustic Image Reconstruction: Mathematical Perspectives

Chapter 7 Recovering a Function from Its Spherical Mean Values in Two and Three Dimensions ..... .. ........ .. ..... .. .... .. ...... . 77

David Finch and Rakesh

Chapter 8 On Reconstruction Formulas and Algorithms for the Thermoacoustic Tomography ..... .......... ..... ........ ........ ..... .. 89

Mark Agranovsky, Peter Kuchment, and Leonid Kunyansky

Chapter 9 Photoacoustic and Thermoacoustic Tomography: Consistency Conditions and the Partial Scan Problem ............. .... ... ........ ........................................................... 103

Sarah K. Patch

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PART IV Photoacoustic Image Reconstruction: Advanced Algorithms

Chapter 10 Time Reversal iri Photoacoustic or Thermoacoustic Tomography ........... .......... ............................................. ... 117

Yuan Xu and Lihong V Wang

Chapter 11 Quantitative Photoacoustic Imaging: Measurement of Absolute Chromophore Concentrations for Physiological and Molecular Imaging ...................................... ................... 121

Paul C. Beard, Jan G. Laufer, Ben Cox, and Simon R. Arridge

Chapter 12 Image Reconstruction in Optoacoustic Tomography Accounting for Frequency-Dependent Attenuation ......... ......... ... .................................................................................. ............. 145

Patrick La Riviere, Jin Zhang, and Mark A. Anastasio

Chapter 13 Half-Time Image Reconstruction in Photoacoustic Tomography ............................. .. ........................... .. ......... 155

Mark A. Anastasio, Jin Zhang, Xiaochuan Pan, and Lihong V Wang

Chapter 14 Adaptive and Robust Methods for Thermoacoustic and Photoacoustic Tomography .................................... .. 165

Bin Guo and Jian Li

PART V Ultrasonic Detectors for Photoacoustic Tomography

Chapter 15 Photoacoustic Imaging with a Double-Ring Sensor ......................................................................................... 183

Roy G.M. Kolkman, Ton G. van Leeuwen, and Wiendelt Steenbergen

Chapter 16 Photoacoustic Tomography Based on Ring-Shaped Virtual Point Ultrasonic Detector.. ................................. 201

Xinmai Yang and Lihong V Wang

Chapter 17 3D Photoacoustic Scanner Based on an Optical Ultrasound-Mapping System for Imaging Superficial Vascular Anatomy In Vivo ..... .. .. ... ............ ... .. ..... .. ... ..... .... ... ..... ........... ... ... .... .. ................ 209

Paul C. Beard, Edward Z. Zhang, and Jan G. Laufer

Chapter 18 High-Frequency Optoacoustic Transducers for Ultrasonic and Photoacoustic Imaging ................................... ... .... ....... ....................................................................... ... ........... 223

Shai Ashkenazi, Yang Hou, Sheng-Wen Huang, Takashi Buma, and Matt O'Donnell

Chapter 19 Interferometry-Based Optoacoustic Tomography ...... .... ...... ......... ......... .......................... ..... .......... ............. ..... 239

Hagyong Kihm, Stefan A. Carp, and Vasan Venugopalan

Chapter 20 Photoacoustic Tomography with Integrating Area and Line Detectors ............................................................ 251

Gunther Paltauf, Robert Nuster, Markus Haltmeier, and Peter Burgholzer

Contents

PART VI Focused Scanning Photoacoustic Tomography with Laser Excitation

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Chapter 21 Dark-Field Confocal Photoacoustic Microscopy .............. .... ............................ .. .... ... ..................................... .. 267

Hao F. Zhang, Konstantin Maslov, and Lihong V Wang

Chapter 22 Deep-Penetrating Reflection-Mode Photoacoustic Imaging ... ... ........... ... ................ ... ................... ................... 281

Kwang Hyun Song and Lihong V Wang

PART VII Array-Based Photoacoustic Tomography with Laser Excitation

Chapter 23 Combined Ultrasound and Photoacoustic System for Real-Time High-Contrast Imaging Using a Linear Array Transducer ................ .. ........................ .. ................................... 289

Michael Jaeger and Martin Frenz

Chapter 24 Fast Photoacoustic Imaging System Based on 320-Element Linear Transducer Array ................................................................................. .................................................. 299

DaXing

Chapter 25 Design and Characterization of an Array-Based Photoacoustic Tomographic System for Small Animal Imaging ...... ...... ..... ..... ........ ... ..... .... ... .... .... .......... .......... ..... .. ...................... ............. 309

John Gamelin, Andres Aguirre, Anastasios Maurudis, Fei Huang, Diego Castillo, Lihong V Wang, and Quing Zhu

PART VIII Thermoacoustic Tomography with Microwave Excitation

Chapter 26 Thermoacoustic Computed Tomography of the Breast... ................................ ................................................... 331

Robert A. Kruger

Chapter 27 Microwave-Induced Acoustic (Thermoacoustic) Tomography ... ..... ... ......... ....... .......... .................. .. ..... ....... .. .. 339

Lihong V Wang

PART IX Functional and Molecular Photoacoustic Tomography

Chapter 28 Functional and Molecular Photoacoustic Tomography of Small-Animal Brains .............................................. 351

Xueding Wang and Lihong V Wang

Chapter 29 Photoacoustic Imaging of Gene Expression in Small Animals In Vivo ............ .... .... ....... ... .... ......................... 363

Roger J. Zemp, Li Li, and Lihong V Wang

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PART X Photoacoustic Tomography with Nanoparticles

Chapter 30 Gold and Silver Nanoparticles as Contrast Agents for Optoacoustic Tomography ......................... ... .. ......... ... 373

Alexander A. Oraevsky

Chapter 31 Photoacoustic Flow Measurements with Gold Nanoparticles ........................................... .. ...................... ..... .. . 387

Pai-Chi Li, Chen-Wei Wei, Sheng-Wen Huang, Chao-Kang Liao, and Churng-Ren Wang

Chapter 32 Photoacoustic Imaging and Therapy Utilizing Molecular Specific Plasmonic Nanoparticles ...... ............. ...... 399

Stanis/av Emelianov, Srivalleesha Mallidi, Timothy Larson, and Konstantin Sokolov

PART XI Photoacoustic Tomography of Breasts, Joints, and Vessels

Chapter 33 Optoacoustic Tomography of the Breast ............ ............................................................................................... .411

Alexander A. Oraevsky

Chapter 34 Photoacoustic Mammography with a Flat Detection Geometry ............................. ......................... .................. 431

Srirang Manohar, Ton G. van Leeuwen, Joost M. Klaase, Frank M. van den Engh, and Wiendelt Steenbergen

Chapter 35 Photoacoustic Tomography: A New Imaging Technology for Inflammatory Arthritis .......... ................. ......... 443

Xueding Wang, David L. Chamberland, Paul L. Carson, and J. Brian Fowlkes

Chapter 36 Intravascular Photoacoustic Imaging of Atherosclerosis ..... ............................................................. ................ 451

Shriram Sethuraman, Bo Wang, Richard Smalling, and Stanis/av Emelianov

Chapter 37 Photoacoustic Depth Determination and Imaging of Port Wine Stain Birthmarks ...................................... ... 463

John A. Viator, Roy G.M. Kolkman, and Wiendelt Steenbergen

PART XII Multimodal Imaging

Chapter 38 Thermoacoustic Reconstruction in Acoustically Heterogeneous Media with the Aid of Ultrasound Tomography ............. ........... ............. ......................... .......................... .................. 473

Xing Jin and Lihong V. Wang

Chapter 39 Role of Photoacoustic and Ultrasound Imaging in Photothermal Therapy .......... ..... ... ...... .. ................ ... ......... 481

Jignesh Shah, Suhyun Park, Salavat Aglyamov, and Stanis/av Emelianov

Index ..................................... ......... .... .... ..... ...... ...... ... ......... ......... ..... .. ................................. ...... ....................... ............... ..... .... 493