Physics, Pharmacy, and the FutureRichard P. McCall, Ph.D.

Professor of PhysicsChair, Department of Basic Sciences

St. Louis College of PharmacySt. Louis, Missouri

Reading glasses• Converging lens• Power• +1.00 D, +1.25 D, +1.50 D, +2.00 D, +2.50 D,

….• Hyperopia (farsightedness) or presbyopia• near point is farther from eye for comfortable

reading• person needs to see close objects clearly

• Example• near point at 40.0 cm, object at 20.0 cm• P = +2.50 D

Earplugs• Difference of two intensity levels related to ratio

of two intensities

• NRR - used to rate effectiveness of earplugs• Typical values range from 12 to 33 dB

Syringes and needles• Flow rate

• Flow rate equation

• Viscosity • Poiseuille’s law

• Dependence on radius to the 4th power: r4 • Needle is rate-limiting step in IV fluid flow

• Pressure difference along needle depends on• height (or depth) of fluid• pressure in vein

Tablets• Scoring surface makes breaking tablet easier• Torque, elastic limit

• Glynase PresTab Tablet • For Type II diabetes• Special shape allows tablet to be split using

one hand• Range of size: 45 to 55% in each piece

The Eye• Acts like a converging lens to produce a real image • Most refraction occurs at the cornea• Lens – small amount of refraction needed for

proper focus – accommodation• To see distant objects • ciliary muscle is relaxed, largest diameter• ligaments pull outward on lens – flatter shape

• To see close objects • ciliary muscle is tense, smaller diameter• ligaments lose tension on lens – fatter shape

• As a person ages• lens becomes denser and less flexible• does not relax to its fatter shape• difficulty seeing close objects (presbyopia)

The Middle Ear• Eardrum, ossicles, and Eustachian tube• Ossicles – malleus (hammer) is connected to the

eardrum; incus (anvil); stapes (stirrup) connected to oval window

• Create much larger force on oval window – needed for wave motion in fluid of inner ear

• This increased force is a result of two factors. • surface area of eardrum compared to stapes• lever system mechanical advantage

ABSTRACTTeaching at a college of pharmacy, I learned early on that it was important to point out the relevance of physics to students. I spent time looking for applications specifically in a pharmacy setting, as well as applications to other courses in the curriculum, including anatomy and physiology. Now in my 18th year of teaching an IPLS course at STLCOP, the College is looking to expand our physics offerings as we begin two new B.S. degree programs this fall. We are also planning a new physics laboratory, with new experiments and equipment. As a new department chair, I am looking for two new physics faculty to develop these courses, labs, and experiments, as well as to develop more advanced elective courses appropriate for life sciences students..

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THE FUTURE OF PHYSICS AT STLCOPTwo new integrated BS/PharmD programs starting Fall 2014

New physics courses being developedNew physics laboratory coming soon

BS in Health SciencesPhysics I and Physics I

BS in Health HumanitiesPrinciples of Physics

Need new faculty interested in developing IPLS courses

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PHYSICS AND PHYSIOLOGYPHYSICS IN THE PHARMACY

Pre-Prof & Prof Year 1 Curriculum for the Integrated BSHS/PharmD (129 credit hours)

FRESHMAN YEAR Fall Spring

Biology I 4 Biology II 4 Chemistry I 4 Chemistry II 4 College Writing I 3 College Writing II 3 Pre-Calculus/Calculus/Statistics 3 Pre-Calculus/Calculus/Statistics 3 Foundations of Learning 2 Introduction to Healthcare 2

TOTAL 16 TOTAL 16

SOPHOMORE YEAR Fall Spring

Anatomy 4 Physiology 4 Chemistry III 4 Chemistry IV 4 Humanities I 3 Humanities II 3 Statistics/Sociology/Psychology 3 Sociology/Psychology 3 Literature or Social Science 3 Literature or Social Science 3

TOTAL 17 TOTAL 17

JUNIOR YEAR Fall Spring

Microbiology or Biochemistry 4 Microbiology or Biochemistry 4 Physics I 4 Physics II 4 Humanities Selective 3 Scientific or Professional Writing Selective 3 Microeconomics w/Healthcare Emphasis or Healthcare Communication 3

Microeconomics w/Healthcare Emphasis or Healthcare Communication 3

Bio/Phys/Health Sci Elective or Open 3 or 0 Open or Bio/Phys/Health Sci Elective 0 or 3 TOTAL 17 or 14 TOTAL 14 or 17

PROFESSIONAL YEAR 1

Fall Spring Principles of Drug Action 4 Intro to Patient Care 4

(Intro, Wellness & Self Care, Derm) Pharmacy Calculations (students can take the proficiency test up to week 4 of the semester)

Innovative Applied Pharmaceutics I 2 (semester long course)

Skills Lab 1 (pre-lab lecture + 2-hr lab; coordinate w/all courses; calculations refresher)

Principles of Molecular Bio/ Genetics (w/lab) 3

Innovative Applied Pharmaceutics II 4 (coordinate w/ skills lab as appropriate)

Public Health Fundamentals 3 in Pharmacy

AND IPPE: Clin Prev/Pop Health 1

Basic Drug Info/Intro to EBM 2 & Informatics

AND Principles of Immunology 2

Medical Physiology 3 Other Elective 3 TOTAL 16 TOTAL 16

Pre-Prof & Prof Year 1 Curriculum for the Integrated BSHH/PharmD (128 credit hours)

FRESHMAN YEAR Fall Spring

Biology I 4 Biology II 4 Chemistry I 4 Chemistry II 4 College Writing I 3 College Writing II 3 Pre-Calculus/Calculus/Statistics 3 Pre-Calculus/Calculus/Statistics 3 Foundations of Learning 2 Introduction to Healthcare 2

TOTAL 16 TOTAL 16

SOPHOMORE YEAR Fall Spring

Anatomy 4 Physiology 4 Chemistry III 4 Chemistry IV 4 Humanities I 3 Humanities II 3 Statistics/Sociology/Psychology 3 Sociology/Psychology 3 Literature or Social Science 3 Literature or Social Science 3

TOTAL 17 TOTAL 17

JUNIOR YEAR Fall Spring

Microbiology or Biochemistry 4 Microbiology or Biochemistry 4 Principles of Physics 4 Health Humanities Selective (Option 1) 3 Humanities Selective 3 Scientific/Professional Writing Selective (Op 2) 3 Microeconomics w/Healthcare Emphasis OR Healthcare Communication 3

Microeconomics w/Healthcare Emphasis OR Healthcare Communication 3

Free elective 3 Health Humanities Selective (Option 3) 3 TOTAL 17 TOTAL 16

PROFESSIONAL YEAR 1

Fall Spring Principles of Drug Action 4 Intro to Patient Care 4

(Intro, Wellness & Self Care, Derm) Pharmacy Calculations (students can take the proficiency test up to week 4 of the semester)

Innovative Applied Pharmaceutics I 2 (semester long course)

Skills Lab 1 (pre-lab lecture + 2-hr lab; coordinate w/all courses; calculations refresher)

Principles of Molecular Bio/ Genetics (w/lab) 3 Innovative Applied Pharmaceutics II 4 (coordinate w/ skills lab as appropriate)

Public Health Fundamentals 3 in Pharmacy

AND IPPE: Clin Prev/Pop Health 1

Basic Drug Info/Intro to EBM 2 & Informatics

AND Principles of Immunology 2

Medical Physiology 3 (open) TOTAL 16 TOTAL 13

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