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7/23/2019 RADIO 250 [8] LEC 09 Musculoskeletal Radiology
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TOPIC OUTLINE
I. Bone TumorsA. ModalitiesB. Diagnostic Criteria
II. Summary
Transers Note:Dr. Galsim didnt give us a copy of his T so !e used the pictures
from the "#$% &uddy CD files and from the internet. 'appy studying( )*
Legend:+rom TMentioned by lecturer
I. BONE TUMORS
Seldom encountered by clinicians
Important to recognize them in future clinical practice
A. MODALITIES
Radiographic findings may not allow precise diagnosis
Provide reliable information on aggressiveness or rate of growth of
bone tumors
Aggressivemalignant; non-aggressivebenign; ecept!
o Aneurysmal bone cyst " osteomyelitis # aggressive but benign
o Ameloblastoma # non-aggressive but malignant
X-RAY
$onventional %& imaging modality
Sensitive techni'ue
Assesses the aggressivenessof the lesion( based on certain criteria
given )e* non-aggressive lesions are benign+
$annot provide a histological diagnosis
,. of bone matri must be destroyed to be observed
ULTRASOUND
/sed for 0oint diseases )e* effusion( edema+
1ot very useful unless with total destruction of the bone corte
2ften used in MS3 for assessment of muscles, tendons, & soft
tissue
CT
/sed for cortical lesions
&etermine calcifiedlesions )appear hyperdense+
/seful for determining the etent of the tumor( for its staging( and for
detecting metastasis )contiguous or distal+
MRI
/sed for marrow, medullary cavity lesions, & soft tissue
4ives superior soft tissue resolution
5i6e $7( useful for determining tumor etent( staging( and metastasis
BONE SCAN
Assesses bone metastasis
/nli6e plain radiographs( bone marrow destruction can be as low as ,
to %. to be detected &etermines level of metabolic activity
8ery sensitive but non-specific
o 9alse positive! degenerative( superimposed inflammatory process( or
from previous thoracotomy
PET
Able to assess functionality
:pensive( but when combined with CT/MRI(etent or status of the
lesion becomes easily defined
B. DIANOSTIC CRITERIA
AE
,ac- dei-en
o Bone radiologisto valuated /### malignant &one tumors0 !hich could &e d!agnosed
"orre"t#$ %&' o( t)e t!*e1ust &y using the patients age
Infant Metastat!" ne+ro,#asto*a
$stto "nddecade !ings tumor
"ndto 2rddecade 3steosarcoma
/# years old and a&ove Metastatic carcinoma0 multiplemyeloma0 and chondrosarcoma
Ta,#e . Most common &one tumors &ased on age groups.
LOCATION IN LON BONE
Parts of a long bone
o :piphysis # one end of the long bone
o
Metaphysis # growth plate regiono &iaphysis # shaft
o 2thers! epiphyseal plate( apophysis( articular cartilage
E!)$s!s 9our most common conditions!
Chondro&lastoma 4!ith calcification in matri5* 6
child
Giant cell tumors 6 adult
2steomyelitis # fungus( 7
Aneurysmal bone cysts
7/23/2019 RADIO 250 [8] LEC 09 Musculoskeletal Radiology
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Lec 09: Musculoskeleal Radiology
R,& 250
Page 4/ 4Avie & Yanyan
0!g+re 1.Metaphyseal tumor 4&ut e5tends to the diaphysis0 so more ofmetadiaphysealinvolvement*. ointed structures are osteosar"o*as0
e5amples of cloudy0 amorphous matrices.
0!g+re 2.D!a)$sea#involvement. E3!ngs sar"o*a in
young patient0 then *+#t!#e *$e#o*a6 older patients 4left*.En")ondro*a!ith pathologic fracture 4right*.
TUMOR MARINS
attern of &one destruction:;one of transition
Most relia&le plain film indicator for aggressive vs. nonarro! =3T 6 !ell
7/23/2019 RADIO 250 [8] LEC 09 Musculoskeletal Radiology
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Lec 09: Musculoskeleal Radiology
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Page 4/ 4Avie & Yanyan
0!g+re 7. ermeative &one lesion !ith a !ide =3T. 8o!er ;one appearsmore lucent than upper.
PERIOSTEAL NE8 BONE 0ORMATION
>hen there is a tumor or infection( the endosteum and periosteum reactand try to contain the lesion*
0!g+re &. Types of periosteal reaction from left to right) 4$* 8amellar0 4"*8aminated:8ayered0 42* Sun&urst0 and 4/* Codmans Triangle.
$. 8amellar
Most common form of bone formation
@ith single layer of ne! &one formation
niform thic-ness 4$mm* and density
'allmar- of a &enign lesion)no surgical intervention necessary+
o :* 1on-ossifying fibroma # benign( should not be touched
o :* $hronic osteomyelitis that?s healed
o @owever( osteoid osteoma is a benign lesion( but re'uires
interventione should 6now how to differentiate between osteoid and chondroid*
$. Chondroid
unctate0 popcorn
7/23/2019 RADIO 250 [8] LEC 09 Musculoskeletal Radiology
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Lec 09: Musculoskeleal Radiology
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Page 4/ 4Avie & Yanyan
0!g+re 4. Chondroid matri5. 'igh grade chondrosarcoma of the left iliac&one. Soft tissue e5tension seen on a5ial T"
0!g+re 5. Chondroid matri5.
". 3steoid
Cloudli-e or amorphous 4chal6-li6e appearance*
1o particular shape
May also present with calcifications
0!g+re 6. 3steoid matri5 in osteosarcoma 4left*. 3steoid osteoma 4right*.
0!g+re %. Intramedullary osteosarcoma of distal femur !ith large softtissue mass e5hi&iting classic osteoid matri5.
II. SUMMARY
Eno!ledge of the radiologic diagnostic criteria for &one tumors !ouldena&le a physician to accurately characteri;e the lesion0 determine itsaggressiveness0 and come up !ith a short list of differentialdiagnoses.
>hat determines how the lesions appear
>hen cells are activated( it can be either!o lastic # osteoblasts form more bone )e* osteosarcoma+
o 5ytic # osteoclasts stimulated
Matri of tumor
END O0 TRANSCRIPTION
REETINS9
A!e:
Than- you for ta-ing pictures0 Trish('ello0 Bloc- F( 8ets eat more of these please )
Yan$an:
'ey Bloc- F( 'urrah for our very first &loc- &onding activity last +riday( HAlso0 lets all attend the T7 practices( T@Th at Calderon 'all andStudent 8ounge( Eamon mamooon( 8TS @I> IT T'IS A7((( J)D: