Report Empyema

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    Empyema

    An accumulation of thick,

    purulent fluid within thepleural space, often with

    fibrin development & aloculated (walled-off) area

    where infection is located

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    Causes/Risk Factors:

    Presence of bacterial pneumonia orlung abscess

    Penetrating chest trauma

    Hematogenous infection of thepleural space

    Nonbacterial infections

    Iatrogenic causes (after thoracic

    surgery or thoracentesis)

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    Assessments with

    PE & NHHSigns & Symptoms:

    FeverNight

    sweatsPleural pain

    CoughDyspnea

    AnorexiaWeight loss

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    Assessments with

    PE & NHHPhysical Exams:

    r or absent breathsounds over affected area

    dullness on chestpercussionr

    fremitus

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    Diagnostic & Lab Studies

    Computed Tomography(CT) scan reveals largeempyema collection with

    atelectic lobe andconsolidation

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    CT scan of chest showing empyemanecessitans (long arrow), a chronic

    untreated empyema that has eroded

    through the thoracic cage and formed a

    subcutaneous abscess (short arrow)

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    CT scan showing empyema with split pleura

    sign (enhancement of the thickened inner

    visceral and outer parietal pleura separated by

    a collection of pleural fluid)

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    Diagnostic & Lab Studies

    Diagnostic Thoracentesis,under ultrasound guidance

    extraction of a cloudy orfrankly purulent fluid; little

    or no offense odor (aerobicpus); foul smelling

    (anaerobic pus)

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    Diagnostic & Lab Studies

    Diagnostic Thoracentesis,under ultrasound guidance

    fluid analysispH < 7.2Glucose 1000

    IU/ml

    Total protein >3g/ml

    WBC > 15,000cells/mm3

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    Diagnostic

    Thoracentesis

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    Presence ofParapneumonic Effusion

    Release of inflammatory

    mediators

    Pathophysiology

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    permeability of thecapilliaries

    Attracts WBCs to the site

    Escape of albumin & otherprotein from the capillaries

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    Pleural fluid

    Presence of free-flowing,protein rich pleural fluid

    (Stage I)

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    Extensive purulentexudate production

    Initiation of fibroblastic

    activity(Stage II)

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    Adherence of the two

    pleural membranes(Stage III)

    Formation of a peel

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    Nursing Diagnosis

    Impaired Gas Exchange r/tcompressed lung

    Acute Pain r/t infection ofthe pleura

    Risk for Activity Intolerancer/t hypoxia secondary to

    empyema

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    Principles of Management

    Help the patient cope withthe condition

    Instruct patient in lung-expanding breathing exercises

    to restore normal respiratoryfunction

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    Pharmacology

    Antibiotic, cephalosporin (secondgeneration) for bacterialinfections;

    Cefuroxime (Zinacef) forstaphylococcal & streptococcal

    organisms; most often selectedinitial antibiotic (Adult: 750-1500mg IV q8h; Pedia:

    150mg/kg/d IV divided q8h)

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    Pharmacology

    Antibiotics, anaerobic infections an aspiration or likely anaerobicinfection is the cause of the

    pneumoniaClindamycin (Cleocin) for gram-

    positive organisms & anaerobes(Adult: 600-1200mg/d IV/IMdivided q6-8h; Pedia: 25-

    40mg/kg/d IV divided q6-8h)

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    Pharmacology

    Antibiotic, Miscellaneous whenmethicillin-resistant S.aureus issuspected.

    Vancomycin (Vancocin, Vancoled) a glycopeptide agent for gram-

    positive (Adult: 500mg IV q6h or1g IV q12h- not to exceed infusionrate of 10mg/min; Pedia:

    40mg/kg/d IV divided tid/qid)

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    Pharmacology

    Thrombolytic Agents convertplasminogen to plasmin, leading toclot lysis.

    Alteplase (Activase) binds tofibrin in a thrombus & converts

    the entrapped plasminogen toplasmin, initiating localfibrinolysis. (administered

    intrapleural via chest tube)

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    Surgery/Special Procedures

    Antibiotic Therapy prescribedin large doses based on the

    causative organismThoracentesis for small fluid

    volume w/c is not too purulentor thick

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    Surgery/Special Procedures

    Tube Thoracostomy forloculated or complicated pleuraleffusions

    Open Chest Drainage viaThoracotomy, including potential

    rib resection for thickenedpleura & removal of the underlyingdiseased pulmonary tissue

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    BioEthics

    Is open thoracotomy

    still a good treatmentoption for the

    management ofempyema in children?

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    Open thoracotomy remains an

    excellent option for managementof stage IIIII empyema inchildren. When openthoracotomy is performed in atimely manner there is low

    morbidity and it provides rapidresolution of symptoms with ashort hospital stay.

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    However, delayed referrals mayresult in advanced pulmonarysepsis and a protracted clinicalcourse. The late results are

    encouraging. Use of thoracoscopyor fibrinolysis should beconsidered on the basis of theirown merit, not on the assumptionof probable adverse outcomes

    after thoracotomy.

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    THATS ALL,

    THANK

    YOU!!!