Sleepiness and Driving Accidents

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  • 8/4/2019 Sleepiness and Driving Accidents

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    doi: 10.1111/j.1365-2869.2009.00818.x

    Sleepiness, near-misses and driving accidents among a

    representative population of French drivers

    P A T R I C I A S A G A S P E 1 , 2 , J A C Q U E S T A I L L A R D 2 , 3 , V I R G I N I E B A Y O N 4 ,

    E M M A N U E L L A G A R D E 5 , N I C H O L A S M O O R E 6 , J A C Q U E S B O U S S U G E 7 ,G U I L L A U M E C H A U M E T 2 , B E R N A R D B I O U L A C 3 and P I E R R E P H I L I P 2 , 3

    1INRETS-LCPC, LEPSIS, Paris, 2GENPPHASS, CHU Bordeaux, Bordeaux, 3CNRS UMR-5227, Universite Bordeaux 2, Bordeaux, 4Hopital

    Hotel-Dieu, Paris, 5INSERM U897, ISPED, Universite Bordeaux 2, Bordeaux, 6INSERM U657, Universite Bordeaux 2, Bordeaux and 7ASFA,

    Paris, France

    Accepted in revised form 28 October 2009; received 12 August 2009

    S U M M A R Y Study objectives were to determine the prevalence of sleepy driving accidents and to

    explore the factors associated with near-miss driving accidents and actual drivingaccidents in France. An epidemiological survey based on telephone interviews was

    conducted on a representative sample of French drivers. The questionnaire included

    sociodemographics, driving and sleep disorder items, and the Epworth sleepiness scale.

    Of 4774 drivers (response rate: 86%), 28% experienced at least one episode of severe

    sleepiness at the wheel (i.e. requiring to stop driving) in the previous year; 11% of

    drivers reported at least one near-miss accident in the previous year (46% sleep-related);

    5.8% of drivers reported at least one accident, 5.2% of these being sleep related (an

    estimate of 90 000 sleep-related accidents per year in France). Sleepy driving accidents

    occurred more often in the city (53.8%), during short trips (84.6%) and during the day

    (84.6%). Using logistic regression, the best predictive factor for near-misses was the

    occurrence of at least one episode of severe sleepiness at the wheel in the past year [odds

    ratio (OR) 6.50, 95% confidence interval (CI), 5.208.12, P < 0.001]. The bestpredictive factors for accidents were being young (1830 years; OR 2.13, 95% CI, 1.51

    3.00, P < 0.001) and experiencing at least one episode of severe sleepiness at the wheel

    (OR 2.03, 95% CI, 1.572.64, P < 0.001). Sleepiness at the wheel is a risk factor as

    important as age for traffic accidents. Near-misses are highly correlated to sleepiness at

    the wheel and should be considered as strong warning signals for future accidents.

    keyword s accidents, age, epidemiology, french drivers, near-misses, sleepiness

    I N T R O D U C T I O N

    Daytime sleepiness is widespread and has a negative impact on

    everyday life (Ohayon et al., 1997). Sleepiness can be defined

    as difficulty in remaining awake even while carrying out

    activities (Dement and Carskadon, 1982).

    Epidemiological studies from the 1990s showed that fatigue

    and sleep-related accidents represent up to 20% of all traffic

    accidents in industrial societies (Connor et al., 2002; Horne

    and Reyner, 1995; Philip et al., 2001). Traffic accidents at work

    or during the trip from work to home are a major cause of

    injury and death among workers (Barger et al., 2005; Harrison

    et al., 1993; Personick and Mushinski, 1997). Though drows-

    iness has been identified as the reason behind fatal road

    crashes and many industrial accidents (Connor et al., 2001b;

    Hakkanen and Summala, 2000, 2001; Mitler et al., 1988,

    1997), many people drive when their alertness is at its lowest

    level and seem not to be concerned by public health campaigns

    alerting drivers about the risk of sleepiness at the wheel

    (Fletcher et al., 2005; Nabi et al., 2006).

    Experimental studies have been conducted to assess the

    impact of sleepiness at the wheel on driving performance. It has

    Correspondence: Pierre Philip, MD, PhD, Universite Bordeaux 2,

    CNRS UMR-5227, GENPPHASS et Clinique du Sommeil (CHU

    Pellegrin), Place Ame lie Raba-Le on, 33076 Bordeaux Cedex, France.

    Tel.: 33 5 57 82 01 73; fax: 33 5 57 82 00 38; e-mail: [email protected]

    J. Sleep Res. (2010) 19, 578584 Sleep and driving

    578 2010 European Sleep Research Society

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    been demonstratedthat healthy subjects driving in themiddle of

    the night present major driving impairment related to circadian

    and homeostatic pressure (Philip et al., 2006),and that extended

    driving impairs nocturnal driving performances (Sagaspe et al.,

    2008). Many drivers are also patients affected by sleep disorders

    and have to manage deteriorated driving skills (Sagaspe et al.,

    2007). A recent 100-car naturalistic driving study using ques-

    tionnaires about driver sleep habits and instrumented vehicles

    with video-recording for 1 year found that 12% of crashes (and10% of near-crashes) were related to drowsiness (Dingus et al.,

    2006). Drowsy driving crashes tend to occur late at night when

    thecircadian physiological sleep pressure is at its highest (Mitler

    et al., 1997). They also tend to occur on major highways at

    higher speeds leading to greater morbidity and they dispropor-

    tionately involve young men (as do motor vehicle crashes in

    general; Horne and Reyner, 1995; Pack et al., 1995).

    In France, fatigue has been studied as a road traffic crash

    risk factor (Philip et al., 2001), but data on the role of

    sleepiness in the burden of road accidents in this country are

    missing.

    France has decreased drastically its accidental rate from

    8000 deaths per year in 2000 to 4800 in 2008 (Observatoire

    National Interministe riel de Se curite Routie` re (ONISR),

    2008). Behavioral factors like sleepiness start being considered

    as future targets to reduce death and injuries on French roads.

    Following a national campaign directed by the French

    Ministry of Transport on the risk of sleep-related accidents,

    the French Highway Association (Association des Socie te s

    Francaise dAutoroute, ASFA), a not-for-profit foundation

    whose mission is to provide information about highway

    accidents and prevent them, commissioned our team to

    conduct a study on sleepiness at the wheel in order to inform

    and educate drivers via public campaigns.

    We investigated driving accidents and near-miss accidentsusing data extracted from a self-reported telephone-based

    survey of a representative sample of French drivers (n = 5000)

    in order to: (1) evaluate the prevalence of daytime sleepiness

    and prevalence of self-reported sleepy driving accidents; and

    (2) test the associations of demographic, driving, behaviors

    and sleep disorders variables with both self-reported near-miss

    accidents and actual driving accidents.

    M A T E R I A L S A N D M E T H O D S

    Sample

    Association des Socie te s Francaise dAutoroute provided our

    research team with access to a telephone database of citizens

    representative of the population of French drivers.

    Out of 18 million telephone numbers (French homes base)

    of the society Pages Jaunes Marketing Service, 20 846

    telephone numbers were randomly selected according to some

    defined quotas representative of the national statistics on

    French drivers of personal vehicles: department, age, gender,

    type of home and socio-professional status. From October to

    November 2007, 5000 interviews were obtained by telephone

    from this selected base (5555 drivers were contacted and 5000

    accepted to be interviewed). We eliminated an extra 226

    questionnaires with missing or inappropriate responses, and

    we ran our analyses on a sample of 4774 drivers (response rate:

    86%).

    Our team prepared a specific telephone questionnaire

    designed to collect information from this large cohort of

    French drivers about the prevalence of daytime sleepiness and

    prevalence of self-reported sleepy driving accidents, andcontribution of demographic, driving, behaviors and sleep

    disorders variables in near-misses and accidents. A near-miss

    driving accident was defined as an event that had not caused

    any harm and therefore had limited immediate impact (e.g.

    inappropriate line crossing). A driving accident was defined

    only if material damage or physical injury occurred.

    A questionnaire took a mean of 10 min to be completed.

    The questionnaires were completed by 30 interviewers operat-

    ing for an independent company specializing in phone-based

    medical studies. To minimize potential bias, these interviewers

    were overseen by supervisors and a psychologist specially

    trained by a sleep specialist of our team working on sleepiness

    at the wheel. We, for instance, clearly explained to the

    interviewers the difference between fatigue and sleepiness at

    the wheel. The rationale of the study and the proper strategy

    were particularly emphasized.

    Volunteers had to respond to the following.

    1. Thirty-one questions covering information on gender, age,

    body mass index (BMI), marital status, profession and

    driving habits.

    2. Two questions exploring the occurrence of near-misses and

    driving accidents.

    3. A set of 10 questions previously used in an epidemiological

    survey (Philip et al., 1999) exploring frequency and condi-

    tions where sleepiness at the wheel affected drivers. Sixquestions explored the consumption of alcohol, coffee and

    caffeinated beverages. The potential effects on alertness of

    coffee and taking a nap were also investigated to explore

    countermeasures to sleepiness.

    4. Specific questions from the Basic Nordic Sleep Question-

    naire (Partinen and Gislason, 1995) to explore the snoring

    frequency.

    5. The Epworth Sleepiness Scale (ESS; Johns, 1991) to explore

    excessive daytime somnolence. The ESS is an eight-item

    questionnaire designed to evaluate the subjects likelihood of

    falling asleep in common situations.

    6. Patients were also asked if they had ever been diagnosed and

    treated for sleep disorders [obstructive sleep apnoea syn-

    drome (OSAS), restless legs syndrome (RLS), insomnia,

    narcolepsy hypersomnia] or psychiatric disorders (anxiety

    or depression).

    Statistical analyses

    Quantitative variables were expressed as mean and standard

    deviation (SD), and qualitative variables were expressed as

    relative frequency.

    Sleepiness, near-misses and driving accidents in France 579

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    For regression analyses, all variables associated with driving

    accidents and near-miss driving accidents were initially exam-

    ined separately using univariate models.

    Time since drivers licence (years), gender, age, BMI

    (kg m)2), marital status, professional driver, ESS scores,

    pathologies, stimulant effect of coffee, tea or cola, stimulant

    effect of nap, severe sleepiness at the wheel needing to stop and

    near-miss accidents during the previous year were submitted as

    independent variables. Years of detention of a driving licencewere categorized by period of 10 years of driving; age was

    classified into 1830, 3150, 5165 and >65 years; BMI was

    analysed as a continuous variable; marital status was catego-

    rized as single, married, separated and divorced or widowed;

    professional driver was dichotomized into yes or no; ESS

    scores were classified into 010 or >11; pathologies were

    classified into OSAS, RLS, insomnia, anxietydepression,

    narcolepsy hypersomnia, multi-pathologies and without sleep

    pathology; stimulant effect of coffee, tea or cola was dichot-

    omized into yes or no; stimulant effect of nap was dichoto-

    mized into yes or no; severe sleepiness at the wheel requiring to

    stop was dichotomized into yes or no; and near-miss accident

    during the previous year was dichotomized into yes or no.

    Multivariate logistic regression analyses were performed for

    all variables that showed a significant association in univariate

    models (P < 0.05) to control confounding factors and to

    determine the main correlates. The referent group for each

    factor was selected as drivers supposed to be at the lowest risk

    for near-misses or accidents.

    A significant association was found between driving acci-

    dents and the following variables: licence, age, marital status,

    professional driver, ESS scores, pathologies, stimulant effect of

    coffee, tea or cola, and severe sleepiness at the wheel needing to

    stop. As near-miss driving accidents is a well-known predictive

    variable for driving accidents (Powell et al., 2007) and in orderto reduce co-linearity with severe sleepiness episodes at the

    wheel, we decided to not include in the model this specific

    variable.

    A significant association was found between near-miss

    driving accidents and the following variables: licence, gender,

    age, BMI, marital status, professional driver, ESS scores,

    pathologies, stimulant effect of coffee, tea or cola, stimulant

    effect of nap and severe sleepiness at the wheel needing to stop.

    Statistical tests of the regression estimates odds ratio (ORs)

    were based on Wald statistics. Odds ratio and their 95%

    confidence intervals (CIs) are presented to show the associa-

    tion.

    All analyses were performed using spss statistical software

    package (SPSS, version12.0, Chicago, IL, USA).

    R E S U L T S

    Sample

    Table 1 summarizes the demographic characteristics of the

    sample. Half of the responders were females (54.3%). The

    mean age was 48.5 15.5 years. The BMI ranged from 14 to

    61 kg m)2. Most of the subjects were married (72.1%), 59.5%

    of the subjects declared to have a job and 11.5 self-considered

    themselves as a professional driver.

    Table 1 Demographic characteristics of the 4774 respondents

    Characteristics

    Percent or

    Mean SD

    Age (years) (%)

    1830 12.7

    3150 43.8

    5165 27.7

    >65 15.8

    Female (%) 54.3BMI (kg m)2) 24.4 4.2

    Marital status (%)

    Married 72.1

    Single 14.6

    Separated or divorced 11.9

    Missing 1.4

    Number of children 1.8 1.3

    Professional status (%)

    Farmers 1.9

    Artisans 3.1

    Senior executive 8.5

    Middle management 15.0

    Employees 19.5

    Working class 16.4

    Retired 26.0

    Non-worker 9.6

    With a job (%) 59.5

    Work (%)

    Diurnal work 87.4

    Nocturnal work 2.8

    Shift work 9.8

    Missing 0

    Time of work per week (h) 37.5 10.6

    Main reasons for driving on road (%)

    Homework 52.3

    Professional reason 7.4

    Hobbies 30.6

    Shopping 7.9

    Weekend 0.6

    Holidays 0.4

    None 0.8

    Licence (years) 26.2 14.0

    Frequency of driving a car (%)

    Once or more per day 70.0

    Once or more per week 27.9

    Once or more per month 1.2

    Once or more per year 0.3

    Missing 0.6

    Kilometers driven per year (%)

    05000 15.1

    500010 000 20.5

    10 00015 000 21.7

    15 00025 000 24.5

    25 00040 000 11.8

    >40 000 5.6

    Missing 0.8

    Percentage of driving between 00:00

    and 06:00 hours

    11.8 7.6

    Self-considered as professional drivers (%) 11.5

    BMI, body mass index.

    580 P. Sagaspe et al.

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    Prevalence of sleep complaints

    The mean score for the ESS was 5.7 3.8. The prevalence of

    excessive daytime sleepiness in our population was 11.8% (ESS

    score 11), 1% reported an ESS score >16.

    Sleepiness at the wheel

    Over one-quarter of the respondents (28.2%) declared they

    experienced at least one episode of severe sleepiness at the

    wheel (i.e. requiring to stop driving) in the previous year

    (Table 2).

    Near-miss driving accidents

    One-tenth of the drivers (10.7%; 510 of 4774) reported at least

    one near-miss accident during the previous year, 46% of these

    being reportedly sleep-related (4.9% of drivers; 233 of 4774).

    Near-miss sleepy accidents principally occurred on a highway

    (77.6%), during a long trip (63.8%), and occurred more often

    during the night (40.9%) than the day (29.4%). Young drivers

    (1830 years) were the most exposed group to both all near-misses (1830 years: 19.6%; 117 of 597; 3150 years old:

    11.8%; 2502115; 5165 years old: 7.8%; 102 of 1312; and

    >65 years old: 5.5%; 41750) and to sleep-related near-misses

    (1830 years: 10.1%; 60 of 597; 3150 years old: 5.7%;

    1202115; 5165 years old: 3.4%; 45 of 1312; and >65 years

    old: 1.1%; 8 750).

    Driving accidents

    In the past year, 5.8% of drivers (278 of 4774) reported at least

    one driving accident, and 5.2% of these were sleep related (13

    of 4774). Sleepy driving accidents occurred more often in the

    city (53.8%). They concerned more often short trips (84.6%),

    and most of them occurred during the day (84.6%).

    Young drivers were the most exposed group to accidents

    (1830 years: 12.9%; 77 of 597; 3150 years old: 6.1%;

    1302115; 5165 years old: 3.4%; 45 of 1312; and >65 years

    old: 3.5%; 26750).

    Factors associated with near-miss driving accidents and actual

    driving accidents

    Table 3 describes the risk factors associated with near-miss

    accidents.

    Males had 1.51 (95% CI, 1.221.87, P < 0.001) morechances to be involved in a near-miss accident than females.

    Compared with our reference group (3150-year-old drivers),

    5165-year-old drivers near-miss accidental risk was associ-

    ated with a reduction to 0.75 (95% CI, 0.570.98, P < 0.05),

    whereas 1830-year-old drivers near-miss accidental risk was

    associated with an increase to 1.86 (95% CI, 1.412.44,

    P < 0.001). Being sleepy (ESS score 11) was associated with

    a risk of near-miss driving accidents (OR 1.67, 95% CI, 1.29

    2.15, P < 0.001). Interestingly, we found that

    Table 2 Sleepiness at the wheel, near-misses and traffic accidents

    Characteristics

    Percent or

    Mean SD

    ESS 5.7 3.8

    Severe sleepiness at the wheel needing to stop (%)

    Never 71.8

    Less than once per month 24.4

    At least once per month 3.1

    At least once per week 0.7Sleepy during (%)

    Nocturnal driving 46.8

    Diurnal driving 39.4

    Both 13.8

    Near-miss driving accidents during

    previous year (at least once) (%)

    10.7

    Near-miss sleepy driving accidents

    during previous year (at least once) (%)

    4.9

    Number of near-miss sleepy

    driving accidents during

    previous year

    4.4 14.5

    Location of near-miss sleepy

    driving accidents (%)

    City 2.2

    Road 35.1

    Highway 59.3

    All types of roads 3.4

    Type of trip for near-miss sleepy

    driving accidents (%)

    Short trip 40.3

    Long trip 57.6

    All type of trips 2.1

    Time of day for near-miss sleepy

    driving accidents (%)

    Day 44.6

    Night 45

    Day and night 10.4

    Driving accidents during previous

    year (at least once) (%)

    5.8

    Sleepy driving accidents during previous

    year (at least once) (%)

    0.3

    Number of sleepy driving accidents

    during previous year

    1.1 0.3

    Location of sleepy driving

    accidents (%)

    City 53.8

    Road 38.5

    Highway 7.7

    Type of trip for sleepy driving

    accidents (%)

    Short trip 84.6

    Long trip 15.4

    Time of day for sleepy driving accidents (%)

    Day 84.6

    Night 15.4

    Anticipatory measures before departure (%) 55.6

    Type of preparation (%)

    Normal sleep duration 68.6

    Earlier departure in order to plan breaks 12.7

    Plan to sleep during breaks 5.5

    Take stimulant drinks 3.7

    Second rested driver 6.8

    Nothing 2.7

    ESS, Epworth Sleepiness Scale.

    Sleepiness, near-misses and driving accidents in France 581

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    anxietydepression was also predictive for accidental risk (OR

    1.82, 95% CI, 1.272.62, P < 0.001). Subjectively, caffeine-

    sensitive drivers accidental risk was 1.20 (95% CI, 0.971.47,P = 0.09) compared with insensitive drivers. Finally, experi-

    encing at least one episode of severe sleepiness at the wheel in

    the previous year was associated with a 6.50-fold increase

    (95% CI, 5.208.12, P < 0.001) in the near-miss accident

    rate.

    Table 4 contains information about the risk factors associ-

    ated with driving accidents.

    Unmarried drivers had 1.40 (95% CI, 0.991.96, P < 0.05)

    more chances to be involved in an accident than married

    drivers. Compared with our reference group (3150-year-old

    drivers), 5165-year-old drivers accidental risk was associated

    with a reduction to 0.63 (95% CI, 0.440.90, P < 0.01),

    whereas 1830-year-old drivers accidental risk was associated

    with an increase to 2.13 (95% CI, 1.513.00, P < 0.001).

    Professional drivers were at higher risk of driving accidents

    than non-professionals (OR 1.52, 95% CI, 1.082.13,

    P < 0.05). Subjectively, caffeine-sensitive drivers accidental

    risk was 1.43 (95% CI, 1.111.85, P < 0.01) compared with

    insensitive drivers. Finally, experiencing at least one episode of

    severe sleepiness at the wheel in the previous year was

    associated with a 2.03-fold increase (95% CI, 1.572.64,

    P < 0.001) in the accident rate.

    D I S C U S S I O N

    Our study is the first one to focus on sleepiness, near-missesand accidental risk among a population of regular French

    drivers. Our sample matches the general population of drivers

    in France, and therefore our results should be applicable to the

    French population.

    Our data show that one-third of French drivers experienced

    at least one episode of severe sleepiness at the wheel (i.e.

    requiring to stop driving) in the previous year. This ratio

    matches with that of a French study (Nabi et al., 2006)

    investigating workers of the GAZEL cohort. This episode of

    sleepiness at the wheel is a major contributing factor to the

    occurrence of near-miss accidents or actual accidents. This

    result corroborates Connor et al.s study (Connor et al., 2002)

    showing that acute sleepiness in car drivers significantly

    increases the risk of a crash.

    In our sample, 11.8% complained of excessive chronic

    daytime somnolence (ESS 11). We have shown an association

    between pathological ESS scores and near-miss driving acci-

    dents but, contrary to the Powell study (Powell et al., 2007),

    we did not found such an association between ESS scores and

    accidents. In the Powell study, near-miss accidents and

    accidents were reported over a 3-year period, increasing the

    statistical power and not only in the previous year like we did

    Table 3 Multivariate logistic regression results for prediction of near-miss driving accidents

    Total (n)

    Near-miss driving accident

    OR (95% CI) P-valueYes (n) %

    Gender

    Male 2178 288 13.2 1.51 (1.221.87) 0.001

    Female 2596 222 8.6 Referent

    Age (years)

    3150 2115 250 11.8 Referent1830 597 117 19.6 1.86 (1.412.44) 0.001

    5165 1312 102 7.8 0.75 (0.570.98) 0.05

    >65 750 41 5.5 NS

    ESS

    010 4134 384 9.3 Referent 0.001

    11 565 117 20.7 1.67 (1.292.15)

    Pathologies

    Controls 3310 316 9.5 Referent

    OSAS 105 13 12.4 NS

    RLS 93 14 15.1 NS

    Insomnia 424 46 10.8 NS

    Anxietydepression 348 54 15.5 1.82 (1.272.62) 0.001

    Narcolepsy hypersomnia 7 1 14.3 NS

    Multi-pathologies 487 66 13.6 NS

    Stimulant effect of coffee, tea or colaNo 2964 277 9.3 Referent

    Yes 1750 230 13.1 1.20 (0.971.47) 0.090

    Severe sleepiness at the wheel needing to stop

    No 3363 147 4.4 Referent

    Yes 1411 363 25.7 6.50 (5.208.12) 0.001

    CI, confidence intervals; ESS, Epworth Sleepiness Scale; OR, odds ratio; OSAS, obstructive sleep apnoea syndrome; RLS, restless legs

    syndrome.

    582 P. Sagaspe et al.

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    in our study. Moreover, only 1% of our sample reports an ESS

    score over 16. This relatively low frequency (Baldwin et al.,

    2004) could be explained by the fact that our sample of drivers

    is active and healthy (Connor et al., 2001a). However, our

    result is in line with the one of Connor et al. (2002), indicating

    no increase of severe accidental risk (i.e. injured drivers)

    associated with measures of chronic sleepiness. Possibly falling

    asleep in common situations (up to a certain degree of severity,

    i.e. 11 < ESS score < 15) does not necessarily accurately

    predict an accident risk. Another possible explanation could

    be that sleepiness while driving has a major statistical weightcompared with chronic daytime sleepiness (ESS score), and

    thereforewe removed thisvariablefrom our model. We observed

    no relationship between snoring and sleep-related accidents.

    Our survey shows that sleepiness at the wheel is a risk factor

    as important as age for traffic accidents. Young drivers (18

    30 years old) are at particular risk for accidents because they

    present a high propensity to risk taking, alcohol or substance

    consumption (Calafat et al., 2009; Zakletskaia et al., 2009).

    We show that being subjectively sensitive to caffeinated

    products (coffee, tea or cola) is a risk factor for near-misses

    and traffic accidents. Our results go in line with a study (Retey

    et al., 2006) demonstrating that subjects with the largest

    impairment from one night of sleep deprivation (i.e. vulnerable

    subjects) show the largest benefit from caffeine (i.e. caffeine-

    sensitive subjects). Caffeine is an adenosine receptor antago-

    nist, and adenosinergic mechanisms could therefore be a good

    candidate to explain inter-individual differences to vulnerabil-

    ity to sleep loss.

    Near-miss accidents are more frequent than actual driving

    accidents. A study (Powell et al., 2007) has shown that driving

    near-miss sleepy accidents are dangerous precursors to actual

    driving accidents. Near-misses are known to be highly corre-

    lated to sleepiness at the wheel and should be considered as

    strong warning signals for future accidents.

    Interestingly, in our study, sleep-related near-miss accidents

    occurred preferentially on the highway irrespective of duration

    or timing of the trip. Sleep-related accidents occurred prefer-

    entially in the city or on the open road, on a short trip and

    during the day. Driving in a city or on an open road during the

    day exposes the drivers to cross a higher number of vehicles or

    obstacles, which could explain the occurrence of these accidents.

    Our drivers report a higher rate of accidents (six accidents per

    100 drivers) than the official police force statistics (threeaccidents per 1000 drivers; Observatoire National Interministe -

    riel de Se curite Routie` re (ONISR), 2008). This high number is

    probably due to the lower severity of our accidents. Many of

    these probably did not result in traffic disruption or physical

    injury, but simply in vehicle damage. Obviously we missed fatal

    accidents, and probably the severely injured that could not

    respond to a telephone survey. Even if the number of severely

    injured drivers is probably low in our sample, the very high

    number of total accidents represents a major cost for society.

    Another interesting point is the fact that sleep-related

    accidents represent a low proportion of total accidents in our

    sample compared with national highway data (30% of total

    accidents in the previous year; ASFA, 2008) or other epide-

    miological studies conducted in developed countries (Connor

    et al., 2002). Previous studies (National Transportation Safety

    Board, 1990, 1995) showed that sleep-related accidents are

    more severe than non-sleep-related accidents, and we suspect

    that hospitalized victims of accidents were underrepresented in

    our sample of responders. Even so, extrapolated to the French

    general population (30 million drivers), sleepiness could

    account for 90 000 accidents per year, a massive financial

    burden for the French society.

    Table 4 Multivariate logistic regression results for prediction of driving accidents

    Total (n)

    Driving accident

    OR (95% CI) P-valueYes (n) %

    Age (years)

    3150 2115 130 6.1 Referent

    1830 597 77 12.9 2.13 (1.513.00) 0.001

    5165 1312 45 3.4 0.63 (0.440.90) 0.01

    >65 750 26 3.5 NSMarital status

    Married 3456 170 4.9 Referent

    Single 687 69 10 1.40 (0.991.96) 0.05

    Separated or divorced or widowed 562 38 6.8 1.78 (1.212.61) 0.01

    Professional driver

    No 4146 225 5.4 Referent

    Yes 535 48 9.0 1.52 (1.082.13) 0.05

    Stimulant effect of coffee, tea or cola

    No 2964 147 5.0 Referent

    Yes 1750 127 7.3 1.43 (1.111.85) 0.01

    Severe sleepiness at the wheel needing to stop

    No 3363 140 4.2 Referent

    Yes 1411 138 9.8 2.03 (1.572.64) 0.001

    CI, confidence intervals; OR, odds ratio.

    Sleepiness, near-misses and driving accidents in France 583

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    7/7

    Some methodological issues have to be considered. Near-

    miss driving accidents and driving accidents were self-reported,

    and we did not ask the nature, severity or circumstances of

    material damage and injury. Still our findings are quite

    consistent with other studies (Connor et al., 2002; Powell

    et al., 2007) and we believe that they reflect the reality.

    To conclude, our study shows that sleepiness plays a

    significant role in urban and diurnal minor traffic accidents

    in an active and healthy population (i.e. drivers). Thesefindings are quite new and extend significantly the field of

    accidental risk for sleepiness at the wheel for long distance or

    middle of the night travels to more classical and frequent urban

    trips. Our next step should be to conduct a study similar to

    Connor et al. (2002) in hospitalized French drivers to confirm

    the prevalence of sleep-related accidents in severely injured

    drivers. This new study should give us a full vision of accidental

    risk on French roads in relation to sleepiness at the wheel.

    A C K N O W L E D G E M E N T S

    We thank Sandy Leproust for statistical support.

    D I S C L O S U R E S T A T E M E N T

    No financial conflict of interest.

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