Special Guests:

Manjula Lusti-Narasimhan (WHO)

Ina Park (CDPH)

Bethany Young Holt (CAMI/IMPT)

Women’s Health in Women’s Hands:The Promise of MPTs

2 July 2014 Felicia Stewart Center at UCSF ANSIRH Oakland, California, USA

Women’s Health in Women’s Hands: The Promise of MPTs2 July 2014 – Oakland, California

Multipurpose Prevention TechnologiesMPTs prevent a combination of unintended pregnancy, STIs, HIV/AIDS

Should be safe & easily available

Are designed with key input from women for their specific needs & preferences

Women’s Health in Women’s Hands: The Promise of MPTs2 July 2014 – Oakland, California

Women’s Health in Women’s Hands: The Promise of MPTs2 July 2014 – Oakland, California

What’s in the pipeline?

Small Organic Molecules

Broad Spectrum Natural Products

Proteins/Peptides

Non-Hormonal Contraceptives

Women’s Health in Women’s Hands: The Promise of MPTs2 July 2014 – Oakland, California

WHO Global Reproductive Health Strategy

Promote and strengthen SRH services through:

improving antenatal, delivery, postpartum and newborn care;

providing family planning, including infertility services;

eliminating unsafe abortion; combating STIs, including HIV,

RTIs, cervical cancer and other gynaecological morbidities;

promoting sexual health.

Women’s Health in Women’s Hands: The Promise of MPTs2 July 2014 – Oakland, California

Global Need 222 million women have an unmet

need for modern contraception.

Each day, close to 800 women in developing countries die from complications related to pregnancy and childbirth.

Each year 1.7 million people die from AIDS related causes and 2.5 million become newly infected with HIV.

1 million people contract a sexually transmitted infection every day.

Women’s Health in Women’s Hands: The Promise of MPTs2 July 2014 – Oakland, California

WHO/RHR/HRP Core Functions

Identifying gaps and priorities and shaping the global SRH research agenda

Providing leadership on matters critical to improving SRH through knowledge generation, synthesis and management

Supporting national research, technical capacity strengthening and engaging in relevant partnerships

Articulating ethical and evidence-based options for policy formulation and programme development to improve SRH, in collaboration with regional and country offices

Monitoring and evaluation of SRH situations and trends, advocacy, catalysing change and supporting intervention delivery

Developing of WHO guidelines: clinical standards, norms and related policy and technical guidance documents

Developing pre-qualification of products

Women’s Health in Women’s Hands: The Promise of MPTs2 July 2014 – Oakland, California

Case Study: Kajiata• Age 33, married• Lives in region with high rates

of HIV and HSV-1• Already has 6 children• Currently gets the Depo

injection• Husband spends a significant

amount of time out of the village and she accepts he is unfaithful

• Husband will not wear a condom

Women’s Health in Women’s Hands: The Promise of MPTs2 July 2014 – Oakland, California

Case Study: Angie

• Age 19• Lives in region of the US with

high incidence of chlamydia• Currently using long acting

reversible contraception • No longer in a committed

relationship• Doesn’t always use a condom

Women’s Health in Women’s Hands: The Promise of MPTs2 July 2014 – Oakland, California

Consequences of STIs STIs enhance the biological risk for HIV infection

and transmission and can impact how the disease progresses.

Long-term health consequences of STIs include:

Cervical cancer

Pelvic inflammatory disease

Infertility

Tubal or ectopic pregnancy

Infants born to infected mothers can suffer from perinatal or congenital infections.

Women’s Health in Women’s Hands: The Promise of MPTs2 July 2014 – Oakland, California

In the United States Nearly half of all

pregnancies among American women are unintended.

STIs are the most commonly reported communicable diseases in the US.

There are18.9 million new cases of STIs each year in the US, half of them among 15-24 year olds.

Source: Guttmacher Institute

Women’s Health in Women’s Hands: The Promise of MPTs2 July 2014 – Oakland, California

Chlamydia, Gonorrhea, and Primary & Secondary SyphilisCalifornia Rates, 1990–2012

0

100

200

300

400

500

1990 '92 '94 '96 '98 2000 '02 '04 '06 '08 2010 '12

Year

Ra

te p

er

10

0,0

00

po

pu

lati

on

Chlamydia

Gonorrhea

P&S Syphilis 7.8(N=2,936)

89.3(N=33,780)

448.9(N=169,797)

>206,000 cases of bacterial STIs reported in California

Selected STIs in California

Women’s Health in Women’s Hands: The Promise of MPTs2 July 2014 – Oakland, California

Mistimed or Unwanted PregnancyMIHA 2011

Nearly 1/3 of pregnancies in CA are unplanned

Women’s Health in Women’s Hands: The Promise of MPTs2 July 2014 – Oakland, California

Chlamydia Among Females, 2012 Ages 15-24, By County

Women’s Health in Women’s Hands: The Promise of MPTs2 July 2014 – Oakland, California

Chlamydia among females (2012) vs Unplanned Pregnancy (2011)

1) LA County2) Southeastern

CA3) San Joaquin

Valley

Women’s Health in Women’s Hands: The Promise of MPTs2 July 2014 – Oakland, California

Genital Herpes—Initial Visits to Physicians’ Offices, 1966–2012

NOTE: The relative standard errors for genital herpes estimates of more than 100,000 range from 18% to 30%. SOURCE: IMS Health, Integrated Promotional Services ™. IMS Health Report, 1966–2012.

2012-Fig 48. SR, Pg 45

Women’s Health in Women’s Hands: The Promise of MPTs2 July 2014 – Oakland, California

STIs in Women

Women are disproportionately affected by genital herpes

1 in 9 men1 in 5 women

Source: CDC MMWR April 23, 2010 / 59(15);456-459

Women’s Health in Women’s Hands: The Promise of MPTs2 July 2014 – Oakland, California

What you can do?SHARE

Spread the news about life saving MPTs with your colleagues and networks. Visit our website to access factsheets, PowerPoint presentations, MPT meeting reports and other resources.

COLLABORATEJoin the IMPT and help move the research, policy, funding and education efforts forward to save lives – learn more on our website.

CONTRIBUTEYour financial and in-kind support can accelerate MPT education, research and introduction.

Visit www.cami-health.org or www.MPTs101.org to learn more!

Women’s Health in Women’s Hands: The Promise of MPTs2 July 2014 – Oakland, California

Collaboration, advocacy & research to advance MPTs

Women’s Health in Women’s Hands: The Promise of MPTs2 July 2014 – Oakland, California

Collective Impact Approach

Women’s Health in Women’s Hands: The Promise of MPTs2 July 2014 – Oakland, California

Questions?

Women’s Health in Women’s Hands: The Promise of MPTs2 July 2014 – Oakland, California

Acknowledgements Bill & Melinda Gates Foundation Mary Wohlford Foundation USAID World Health Organization The generous support from individual

donors like you!

Women’s Health in Women’s Hands: The Promise of MPTs2 July 2014 – Oakland, California

Support for this project is made possible by the generous support of the American people through the United States Agency for International Development (USAID)

under the terms of the HealthTech Cooperative Agreement #AID-OAA-A-11-00051, managed by PATH. The contents are the responsibility of CAMI/PHI and its partners

and do not necessarily reflect the views of USAID or the US Government.

Thank You!