The ESFRI Research Infrastructures in the innovation chain ... · innovation chain: diversity of their industrial interactions ESFRI RIs of pan-European interest Definition and types

TTO CIRCLE Network Workshop | Gothenburg | 30 Nov.-01 Dec. 2017 1

The ESFRI Research Infrastructures in the innovation chain: diversity of their

industrial interactions

JEAN MOULIN


The ESFRI Research Infrastructures in the innovation chain: diversity of their

industrial interactions

ESFRI RIs of pan-European interest Definition and types | The Roadmap 2016

RIs in the innovation chain Industry as a supplier, a user and a partner of RIs Recommendations of the ESFRI WG on Innovation

Current practices of ESFRI RIs Industrial access to ESFRI Landmarks Biomedicine & Pharmacy | Analytical facilities | HPC

Concluding remarks


Facilities, resources or services of a unique nature identified by European research commu-nities to conduct top-level research activities and foster innovation in their fields

Where relevant, they may be used beyond research, e.g. for education or public services

Single-sited, virtual, mobile or distributed

Major scientific equipment (or sets of instruments)

Knowledge-based resources (collections, archives or scientific data)

e-Infrastructures (data and computing systems; communication networks)

Any other infrastructure of a unique nature essential to achieve excellence in research and innovation

ESFRI identifies RIs of pan-European interest meeting the long-term needs of Europe’s research communities across all scientific areas


RIs contribute to making Europe 2020 Strategy and its Innovation Union Flagship Initiative a reality

RIs should increase their socio-economic and societal impact:

Contribute to realise the potential of the regions

Identify and promote their innovation and industrial capabilities

Continue their opening to, and partnership with, industrial researchers and industry / services to help to address societal challenges and to support EU competitiveness

Identify the specific requirements for hosting industry users

Increase their international cooperation

Full exploitation of the RIs’ potential as innovation hubs does strengthen their Long-Term Sustainability

RIs are a key instrument in bringing together researchers, funding agencies, policy makers and industry to act together


Social &

Cultural

Innovation

(5L + 1P)

Health and Food

(6L + 8P)

Environmental Sciences

(5L + 5P)

Energy

(1L + 4P)

Analytical

Facilities

(5L)

Physical

Sciences

and Engineering

(6L + 3P)

e-Infra-

Struc-

tures

(1L)

CESSDA BBMRI EMBRC EMSO ACTRIS JHR EMFL E-ELT CTA PRACE

CLARIN EATRIS EMPHASIS EURO-

ARGO DANUBIUS-

RI ECCSEL

ESRF

Upgrades ELI EST

DARIAH ECRIN ERINHA IAGOS EISCAT_3D EU-

SOLARIS European

XFEL FAIR KM3Net

European

Social

Survey

ELIXIR EU-OPEN-

SCREEN ICOS EPOS MYRRHA ESS HL-LHC

SHARE INFRA

FRONTIER

EuroBio-

Imaging LifeWatch SIOS

WIND-

SCANNER ILL20/20

Upgrade SKA

E-RIHS INSTRUCT ISBE SPIRAL

2

ANAEE MIRRI

Roadmap 2016

29 Landmarks (L)

21 Projects (P) Landmarks are successfully implemented ESFRI projects that are delivering science services or effectively advancing in their

construction


RIs are privileged places where research meets innovation & industry (in the form of industrial applications, technologies and business): - they bring together highly skilled scientists, engineers,

technicians and managers, funding agencies, public authorities, policy decision-makers and industry (including SMEs);

- they are characterised by their scientific and technical multi- and cross-disciplinarity and a mix of a very broad range of interactions with their economic and societal surrounding environments

RIs provide a critical mass of instrumentation available or the capability to develop new one and are able, under certain conditions, to mobilise rapidly (with very short delays) their capacities in order to find solutions to the industrial demand

RIs(*) in the innovation chain (1)

(*) Not only the ESFRI RIs !


RIs are major drivers of (industrial) innovation: - in their construction and major upgrade phases

(design, engineering, commissioning), with high opportunities for TT, as sources of (pre-) commercial procurements and purchasers of new high-tech components, instruments and related services;

- in their operation phases, as facilities serving industrial research and innovation, offering opportunities to remove technological barriers leading to further innovation and to generate KT

RIs serve S&T but also policy-making and society. Most of the ESFRI RIs in the Environmental, Health and Food and SSH sectors were built for their mixed scientific, social and societal impact, providing new knowledge, data and services to increase the security, well-being and prosperity of a society faced with a series of Grand Challenges

RIs in the innovation chain (2)

Industry as a supplier

Industry as a user


RIs can offer industrial companies to be immersed in active ecosystems of innovation based on their complementary broad range of competences and skills: - they are most often located in S&T areas (scientific campuses,

technology parks, etc.) that include a wide variety of state of the art enabling technologies and support services (and often several RIs, e.g. as in Hamburg, Lund, Grenoble, Didcot, etc.)

- such an environment enables the creation of a unique ecosystem around RIs well suited for innovation where research teams, standards and metrology services, small high-tech enterprises, spin-off and start-up companies, detached labs of big companies, TTOs and ILOs staffs all together can exploit the "business at walking distance" advantage in working together on common issues in the same place (co-creation)


Industry as a partner


Diversity of forms of RI-Industry interactions

New knowledge production and dissemination: Publications | Access to data and tools for accessing them | Outreach

Access to infrastructures, including provision of specialist service and expertise: with appropriate access and charging mechanisms

Training and human resources development: Knowledge Transfer | Staff mobility

Contribution to economic activities: Design and co-design of instrumentation and equipment, incl. innovative public procurement (mainly for construction/upgrade) Joint research projects (with dedicated funding and interface) Contract R&D, incl. testing (provision of specialist services) Licensing of IP Spin-off creation, business incubation and acceleration services


Interactions between RIs and their surrounding techno-scientific, socio-economic and societal environment


Improving the relations between RIs and Industry and promoting the potential for innovation of RIs in all its aspects | Main recommendations related to “Industry as a user”

Awareness raising on industrial access and services: dissemination and stimulation actions should be carried out in close connection with sectorial industrial organisations and RTOs, with EU support

Installation of Industrial Liaison Officers / Industry Advisory Boards

Innovation Working Group (2016)

Provide companies (including SMEs) with new/more extended room near RIs dedicated to pre-competi-tive research programmes, where the possibility to exploit the RIs technological resources is more effective and where scientists and engineers can work together in the same place on common objectives (open innovation and co-creation)

Quality Chart on access | Remote control access and virtual use | Specific support and services dedicated to industry

Programme-based access Dedicated funding streams for KT and TT,

training and mobility Industry- and innovation-friendly data

policies | Transparent and efficient IPR policies | Appropriate managerial tools

Promotion of local innovation ecosystems


Current practices in industrial access Proportion of total access to the RI

Basic science: from 5% to 85% (100% for purely basic science facilities) Innovation related (involving industrial/civil services): from 10% to 100% (0% for purely basic science facilities). Analytical facilities: up to 30-40%; Health: up to 100%; SSH: up to 20%; Nuclear Energy: up to 70%

Access to the RI Excellence-driven (incl. industrial collaborative research with academic teams): from 80 to 100%. It includes “hidden" market-driven access (analytical facilities and nuclear energy: up to 30%; health: up to 25%) Market-driven "proprietary research" (i.e. purely commercial access): from 0 to 35%. Analytical facilities: up to 3-4%, health: up to 20%; nuclear energy: up to 35%

Access charging in place for industry Excellence-driven collaborative research: - free access for pre-competitive research; - institutions / industry may contribute (in kind) in return for share of novel IPR (e.g. EATRIS); - not for profit rates in the framework of specific agreements (e.g. agreement with a JTI); - PPPs for access in the framework of research programmes (e.g. ESRF+ILL) Proprietary research: full actual cost and industry keeps all IPRs

[From a survey of ESFRI Landmarks (2015) | No figures for environmental facilities]


Focused on supporting in bridging the gap to industry in medicine development where a great deal of capital-intensive applied research is necessary to bring a new drug to a point in which industry becomes interested Industry has access to highly capital intensive facilities and expertise that are otherwise out of reach for companies, especially SMEs Portfolio of research services focused on predicting the performance of a product (drug, medical device), selecting the right patient, and entering clinical development as safely and effectively as possible Product platforms (technology pipelines): Advanced Therapy Medicinal Products (ATMP) | Small Molecules | Vaccines | Imaging and Tracing | Biomarkers Regulatory support | Education and training opportunities

Distributed RI – 90 academic institutions in 12 countries – One single point of access Supports pharmaceutical and biotech industries and medicine development


Matching Europe’s top infrastructure and translational expertise to the best research projects | Facilitates public-private and public-public collaboration Supports the development of novel tools, technologies, and metho-dologies to improve early development of medicines and diagnostics Facilitates any type of project, ranging from one-on-one service agreements for a small-scale study, to multi-site, multi-year experimental medicine collaboration covering an entire portfolio in a therapeutic area | Risk-sharing agreements or services agreements Academic users can access EATRIS to get support in the advancement of their novel drug (target) or diagnostic, so that the IP can be matured to a point of being ready for transfer to industry

Access:

100% innovation related 20% proprietary research


The ESRF Business Development Office (BDO) offers industry a privileged and practical access both to its beamlines and expertise, enabling them to help solve process problems, reduce product-to-market times and enhance R&D programmes Proprietary research is carried out in a completely confidential manner (through the Non-Disclosure Agreement) Pharmaceuticals and Biotech [Pharmaceutical companies use the macromolecular crystallography beamlines for drug design (with possibility of

remote access)]| Health and Medtech | Agriculture and Food | Catalysis and Chemistry | Petrochemicals| Polymers | Aerospace and Automotive | Metallurgy | Engineering | Environment and Mining | Ceramics | Renewable Energy and Energy Storage | Electronics | Nanotech and High Tech Materials | Consumer products

Multidisciplinary analytical facility Centre of excellence for fundamental and innovation-driven research in condensed and living matter science Provides advanced materials characterisation beyond lab facilities


Partnerships with neighbouring institutes (including ILL + EMBL) that extend services to companies and research laboratories beyond the simple access to X-ray beamtime, e.g.: Partnership for Structural Biology | Partnership for Soft Condensed Matter PPP “Large-Scale Facilities Characterisation Platform” with IRT NanoElec (incl. French industry), ILL & CEA: enables the ESRF to work with European electronics’ industries and sets the scene for routine use of nanoscale X-ray beams for commercial R&I Off-line expertise in specialised support laboratories is also available to external clients: Long trace profiler | Crystal Laboratory | Multilayer Laboratory Scientific and engineering expertise: for any service that relates to synchrotron X-ray studies conducted at the ESRF

Access:

22% innovation related

30% of research with industrial partners 3% proprietary research 150 industrial partners


PRACE fosters collaboration and TT/KT between academia & industry. Through implementation projects supported by the EC, PRACE is proposing high-value services for code enabling, training, user support to industry, allowing companies to benefit from the expertise gathered by PRACE partners SHAPE (SME HPC Adoption Programme in Europe) Initiative: support to European SMEs in the use of HPC and advanced numerical simulation, in order to demonstrate that HPC enables SMEs to become more innovative and competitive Industrial Advisory Committee composed of high-level represen-tatives from major European industrial sectors: to advise PRACE in the development of new services towards larger usage of HPC and data services by industry

Distributed RI 5 host countries - 7 super-computers – HPC for basic science, engineering and industrial R&D


PRACE Open Research Model allows European companies access to world-class HPC resources and services in order to increase their competitiveness by reducing the time-to-market, improving reliability and safety of their products, and developing innovative industrial processes Free of charge peer-reviewed access; users do own the data produced by their simulations but they must publish results Welding | Turbines and turbomachinery | Metallurgy | Farming | Molecular dynamics for drug discovery | Nanodevices | Wind power | Etc.

Access: 15% innovation related 0% proprietary research


Other examples in ESFRI RIs Health (biotech, pharma, biomed, nutrition) BBMRI (biobanks + supply biomolecular resources): 15%

inno-related access | Expert centres with industry (PPPs) ECRIN (multinational clinical trials): 95% inno-related

access | Medicines, vaccines, devices, diagnostics INSTRUCT (structural & cell biology): 20% inno-related

access | Drug discovery pipeline, vaccines ELIXIR (data infrastructure): highly used by industry Analytical facilities: ILL and ESS (neutron sources) Nuclear facilities: JHR | FAIR | SPIRAL 2 Materials testing, nuclear medicine, radiobiology &

radiopharmaceuticals Energy RIs (projects): tests & demo for renewable energies


Concluding remarks

“Synergies with the ESFRI network” vs. “Increased accessibility of R&I infrastructure to industry”

Useful examples of good practices in ESFRI RIs: Innovation and industry-oriented strategies are developed and implemented | Potential of the distributed RI model | Multi-disciplinarity | Networking and clusters | Innovation ecosystems |Open innovation and co-creation

Increased cooperation of RIs and RTOs: Awareness raising | Efficient interfaces with industry | Complementarity | Networking


Thank you for your attention

Contact:

[email protected] BELSPO Honorary General advisor

REFERENCES

Report of the ESFRI WG on Innovation (2016) http://www.esfri.eu/esfri-publications-0

Ad hoc WG on Long-Term Sustainability of RIs | Main recommendation 4: “Fully exploit the potential of RIs as innovation hubs“ (2017) http://www.esfri.eu/sites/default/files/u4/ESFRI_SCRIPTA_VOL2_web.pdf

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The ESFRI Research Infrastructures in the innovation chain ... · innovation chain: diversity of their industrial interactions ESFRI RIs of pan-European interest Definition and types